Muscles, exercise and obesity: skeletal muscle as a secretory organ

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Items 101–176 of 176

1. Growth and differentiation factor 15 is secreted by skeletal muscle during exercise and promotes lipolysis in humans
   Laurens, Claire, Parmar, Anisha, Murphy, Enda, Carper, Deborah, Lair, Benjamin, Maes, Pauline, Vion, Julie, Boulet, Nathalie, Fontaine, Coralie, Marquès, Marie et al. · 2020 · JCI Insight
2. Passive and active roles of fat-free mass in the control of energy intake and body composition regulation
   Dulloo, A G, Jacquet, J, Miles-Chan, J L, Schutz, Y · 2017 · European Journal of Clinical Nutrition
3. Systemic Nutrient and Stress Signaling via Myokines and Myometabolites
   Rai, Mamta, Demontis, Fabio · 2016 · Annual Review of Physiology
4. Cytokine response of primary human myotubes in an in vitro exercise model
   Scheler, Mika, Irmler, Martin, Lehr, Stefan, Hartwig, Sonja, Staiger, Harald, Al-Hasani, Hadi, Beckers, Johannes, Hrabé de Angelis, Martin, Häring, Hans-Ulrich, Weigert, Cora · 2013 · American Journal of Physiology-Cell Physiology
5. Understanding the variation in exercise responses to guide personalized physical activity prescriptions
   Noone, John, Mucinski, Justine M., DeLany, James P., Sparks, Lauren M., Goodpaster, Bret H. · 2024 · Cell Metabolism
6. Exercise-Induced Myokines can Explain the Importance of Physical Activity in the Elderly: An Overview
   Kwon, Jenny Hyosun, Moon, Kyoung Min, Min, Kyueng-Whan · 2020 · Healthcare
7. Irisin and myonectin regulation in the insulin resistant muscle: implications to adipose tissue: muscle crosstalk
   Gamas, Luis, Matafome, Paulo, Seiça, Raquel · 2015 · Journal of Diabetes Research
8. Loss of <i>Pgc-1α</i> expression in aging mouse muscle potentiates glucose intolerance and systemic inflammation
   Sczelecki, Sarah, Besse-Patin, Aurèle, Abboud, Alexandra, Kleiner, Sandra, Laznik-Bogoslavski, Dina, Wrann, Christiane D., Ruas, Jorge L., Haibe-Kains, Benjamin, Estall, Jennifer L. · 2014 · American Journal of Physiology-Endocrinology and Metabolism
9. Therapies for Musculoskeletal Disease: Can we Treat Two Birds with One Stone?
   Girgis, Christian M., Mokbel, Nancy, DiGirolamo, Douglas J. · 2014 · Current Osteoporosis Reports
10. Exercise induces white adipose tissue browning across the weight spectrum in humans
    Otero-Díaz, Berenice, Rodríguez-Flores, Marcela, Sánchez-Muñoz, Verónica, Monraz-Preciado, Fernando, Ordoñez-Ortega, Samuel, Becerril-Elias, Vicente, Baay-Guzmán, Guillermina, Obando-Monge, Rodolfo, García-García, Eduardo, Palacios-González, Berenice et al. · 2018 · Frontiers in Physiology
11. Body composition and energy expenditure predict ad-libitum food and macronutrient intake in humans
    Weise, C M, Hohenadel, M G, Krakoff, J, Votruba, S B · 2014 · International Journal of Obesity
12. Home-based resistance training for older adults: a systematic review.
    Thiebaud, Robert S, Funk, Merrill D, Abe, Takashi · 2014 · Geriatrics &amp; Gerontology International
13. Health benefits of exercise — more than meets the eye!
    Febbraio, Mark A. · 2017 · Nature Reviews Endocrinology
14. Protein-dependent regulation of feeding and metabolism
    Morrison, Christopher D., Laeger, Thomas · 2015 · Trends in Endocrinology &amp; Metabolism
15. Mapping the molecular signatures of diet-induced NASH and its regulation by the hepatokine Tsukushi
    Xiong, Xuelian, Wang, Qiuyu, Wang, Shuai, Zhang, Jinglong, Liu, Tongyu, Guo, Liang, Yu, Yonghao, Lin, Jiandie D. · 2019 · Molecular Metabolism
16. IL-15 activates the Jak3/STAT3 signaling pathway to mediate glucose uptake in skeletal muscle cells
    Krolopp, James E., Thornton, Shantaé M., Abbott, Marcia J. · 2016 · Frontiers in Physiology
17. Fibronectin type III domain containing 5 expression in skeletal muscle in chronic heart failure-relevance of inflammatory cytokines
    Matsuo, Yae, Gleitsmann, Konstanze, Mangner, Norman, Werner, Sarah, Fischer, Tina, Bowen, T Scott, Kricke, Angela, Matsumoto, Yasuharu, Kurabayashi, Masahiko, Schuler, Gerhard et al. · 2015 · Journal of Cachexia Sarcopenia and Muscle
18. Thrombospondin 1 Mediates High-Fat Diet-Induced Muscle Fibrosis and Insulin Resistance in Male Mice
    Inoue, Mayumi, Jiang, Yibin, Barnes, Richard H., Tokunaga, Masakuni, Martinez-Santibañez, Gabriel, Geletka, Lynn, Lumeng, Carey N., Buchner, David A., Chun, Tae-Hwa · 2013 · Endocrinology
19. Myokines, physical activity, insulin resistance and autoimmune diseases
    Díaz, Buenaventura Brito, González, Delia Almeida, Gannar, Fadoua, Pérez, M. Cristo Rodríguez, de León, Antonio Cabrera · 2018 · Immunology Letters
20. Myostatin in relation to physical activity and dysglycaemia and its effect on energy metabolism in human skeletal muscle cells
    Hjorth, M., Pourteymour, S., Görgens, S. W., Langleite, T. M., Lee, S., Holen, T., Gulseth, H. L., Birkeland, K. I., Jensen, J., Drevon, C. A. et al. · 2016 · Acta Physiologica
21. Sarcopenic obesity: Myokines as potential diagnostic biomarkers and therapeutic targets?
    Guo, Ai, Li, Kai, Xiao, Qian · 2020 · Experimental Gerontology
22. Irisin ameliorates hepatic glucose/lipid metabolism and enhances cell survival in insulin-resistant human HepG2 cells through adenosine monophosphate-activated protein kinase signaling
    So, Wing Yan, Leung, Po Sing · 2016 · The International Journal of Biochemistry &amp; Cell Biology
23. Interleukin-15 as a myokine: Mechanistic insight into its effect on skeletal muscle metabolism
    Nadeau, Lucien, Aguer, Céline · 2019 · Applied Physiology Nutrition and Metabolism
24. Exercise training mode effects on myokine expression in healthy adults: A systematic review with meta-analysis
    Bettariga, Francesco, Taaffe, Dennis R., Galvão, Daniel A., Lopez, Pedro, Bishop, Chris, Markarian, Anna Maria, Natalucci, Valentina, Kim, Jin-Soo, Newton, Robert U. · 2024 · Journal of Sport and Health Science
25. Myostatin – The Holy Grail for Muscle, Bone, and Fat?
    Buehring, B., Binkley, N. · 2013 · Current Osteoporosis Reports
26. Myonectin deletion promotes adipose fat storage and reduces liver steatosis
    Little, Hannah C., Rodriguez, Susana, Lei, Xia, Tan, Stefanie Y., Stewart, Ashley N., Sahagun, Ageline, Sarver, Dylan C., William Wong, G. · 2019 · The FASEB Journal
27. Exercise-Induced Mitohormesis for the Maintenance of Skeletal Muscle and Healthspan Extension
    Musci, Robert, Hamilton, Karyn, Linden, Melissa · 2019 · Sports
28. Moderate‐intensity treadmill running promotes expansion of the satellite cell pool in young and old mice
    Shefer, Gabi, Rauner, Gat, Stuelsatz, Pascal, Benayahu, Dafna, Yablonka‐Reuveni, Zipora · 2013 · The FEBS Journal
29. Muscle Irisin Response to Aerobic vs HIIT in Overweight Female Adolescents
    Archundia-Herrera, Carolina, Macias-Cervantes, Maciste, Ruiz-Muñoz, Bernardo, Vargas-Ortiz, Katya, Kornhauser, Carlos, Perez-Vazquez, Victoriano · 2017 · Diabetology &amp; Metabolic Syndrome
30. Adiponectin and Its Mimics on Skeletal Muscle: Insulin Sensitizers, Fat Burners, Exercise Mimickers, Muscling Pills … or Everything Together?
    Abou-Samra, Michel, Selvais, Camille M., Dubuisson, Nicolas, Brichard, Sonia M. · 2020 · International Journal of Molecular Sciences
31. Beneficial metabolic activities of inflammatory cytokine interleukin 15 in obesity and type 2 diabetes
    Ye, Jianping · 2015 · Frontiers of Medicine
32. The hepatokine Tsukushi gates energy expenditure via brown fat sympathetic innervation
    Wang, Qiuyu, Sharma, Vishal P., Shen, Hong, Xiao, Yuanyuan, Zhu, Qi, Xiong, Xuelian, Guo, Liang, Jiang, Lin, Ohta, Kunimasa, Li, Siming et al. · 2019 · Nature Metabolism
33. Implication of hepatokines in metabolic disorders and cardiovascular diseases
    Jung, Tae Woo, Yoo, Hye Jin, Choi, Kyung Mook · 2016 · BBA Clinical
34. Strength training reduces circulating interleukin-6 but not brain-derived neurotrophic factor in community-dwelling elderly individuals
    Forti, Louis Nuvagah, Njemini, Rose, Beyer, Ingo, Eelbode, Elke, Meeusen, Romain, Mets, Tony, Bautmans, Ivan · 2014 · AGE
35. A Single Bout of High-intensity Interval Exercise Increases Corticospinal Excitability, Brain-derived Neurotrophic Factor, and Uncarboxylated Osteolcalcin in Sedentary, Healthy Males
    Nicolini, Chiara, Michalski, Bernadeta, Toepp, Stephen L., Turco, Claudia V., D'Hoine, Tarra, Harasym, Diana, Gibala, Martin J., Fahnestock, Margaret, Nelson, Aimee J. · 2020 · Neuroscience
36. Exercise and Self-Reported Limitations in Patients with Inflammatory Bowel Disease
    DeFilippis, Ersilia M., Tabani, Saniya, Warren, Ryan U., Christos, Paul J., Bosworth, Brian P., Scherl, Ellen J. · 2016 · Digestive Diseases and Sciences
37. Adipose–Muscle Crosstalk in Age-Related Metabolic Disorders: The Emerging Roles of Adipo-Myokines
    Fang, Penghua, She, Yuqing, Yu, Mei, Min, Wen, Shang, Wenbin, Zhang, Zhenwen · 2023 · Ageing Research Reviews
38. Myokines as possible therapeutic targets in cancer cachexia
    Manole, Emilia, Ceafalan, Laura C., Popescu, Bogdan O., Dumitru, Carmen, Bastian, Alexandra E. · 2018 · Journal of Immunology Research
39. Acute and chronic increases of circulating FSTL1 normalize energy substrate metabolism in pacing-induced heart failure
    Seki, Mitsuru, Powers, Jeffery C., Maruyama, Sonomi, Zuriaga, Maria A., Wu, Chia-Ling, Kurishima, Clara, Kim, Lydia, Johnson, Jesse, Poidomani, Anthony, Wang, Tao et al. · 2018 · Circulation Heart Failure
40. Myokine/Adipokine response to “Aerobic” exercise: Is it just a matter of exercise load?
    He, Zihong, Tian, Ye, Valenzuela, Pedro L., Huang, Chuanye, Zhao, Jiexiu, Hong, Ping, He, Zilin, Yin, Shuhui, Lucia, Alejandro · 2019 · Frontiers in Physiology
41. Myokines: Metabolic regulation in obesity and type 2 diabetes
    Chen, Zhi-Tian, Weng, Zhi-Xuan, Lin, Jiandie D, Meng, Zhuo-Xian · 2024 · Life Metabolism
42. Role of exercise-induced hepatokines in metabolic disorders
    Ennequin, Gaël, Sirvent, Pascal, Whitham, Martin · 2019 · American Journal of Physiology-Endocrinology and Metabolism
43. The role of myokines and adipokines in hypertension and hypertension-related complications
    Chen, Ken, Zhou, Mengdi, Wang, Xiaomei, Li, Shuang, Yang, Dachun · 2019 · Hypertension Research
44. Regulation of angiopoietin-like protein 4 production during and after exercise
    Norheim, Frode, Hjorth, Marit, Langleite, Torgrim M., Lee, Sindre, Holen, Torgeir, Bindesbøll, Christian, Stadheim, Hans K., Gulseth, Hanne L., Birkeland, Kåre I., Kielland, Anders et al. · 2014 · Physiological Reports
45. Association between sarcopenia and atherosclerosis in elderly patients with ischemic heart disease
    Uchida, Shota, Kamiya, Kentaro, Hamazaki, Nobuaki, Matsuzawa, Ryota, Nozaki, Kohei, Ichikawa, Takafumi, Suzuki, Yuta, Nakamura, Takeshi, Yamashita, Masashi, Kariya, Hidenori et al. · 2020 · Heart and Vessels
46. Physiology of activins/follistatins: Associations with metabolic and anthropometric variables and response to exercise
    Perakakis, Nikolaos, Mougios, Vassilis, Fatouros, Ioannis, Siopi, Aikaterina, Draganidis, Dimitrios, Peradze, Natia, Ghaly, Wael, Mantzoros, Christos S · 2018 · The Journal of Clinical Endocrinology &amp; Metabolism
47. Validity of multi-frequency bioelectric impedance methods to measure body composition in obese patients: a systematic review.
    Becroft, Louise, Ooi, Geraldine, Forsyth, Adrienne, King, Susannah, Tierney, Audrey · 2019 · International Journal of Obesity
48. Exercise biology and medicine: innovative research to improve global health.
    Bamman, Marcas M., Cooper, Dan M., Booth, Frank W., Chin, Eva R., Neufer, P. Darrell, Trappe, Scott, Lightfoot, J. Timothy, Kraus, William E., Joyner, Michael J. · 2014 · Mayo Clinic Proceedings
49. Mitochondrial fat oxidation is essential for lipid-induced inflammation in skeletal muscle in mice
    Warfel, Jaycob D., Bermudez, Estrellita M., Mendoza, Tamra M., Ghosh, Sujoy, Zhang, Jingying, Elks, Carrie M., Mynatt, Randall, Vandanmagsar, Bolormaa · 2016 · Scientific Reports
50. The impact of duration on effectiveness of exercise, the implication for periodization of training and goal setting for individuals who are overfat, a meta-analysis
    Clark, James · 2016 · Biology of Sport
51. Roles of exosome-like vesicles released from inflammatory C2C12 myotubes: regulation of myocyte differentiation and myokine expression
    Kim, Sujin, Lee, Min-Jae, Choi, Ji-Young, Park, Dong-Ho, Kwak, Hyo-Bum, Moon, Sohee, Koh, Je-Woo, Shin, Hun-Kyu, Ryu, Ji-Kan, Park, Chang-Shin et al. · 2018 · Cellular Physiology and Biochemistry
52. Metabolic adaptations after bariatric surgery: Adipokines, myokines and hepatokines
    Faramia, Justine, Ostinelli, Giada, Drolet-Labelle, Virginie, Picard, Frédéric, Tchernof, André · 2020 · Current Opinion in Pharmacology
53. Hydrodynamic delivery of interleukin 15 gene promotes resistance to high fat diet-induced obesity, fatty liver and improves glucose homeostasis
    Sun, H, Liu, D · 2015 · Gene Therapy
54. Exercise-Induced Muscle–Fat Crosstalk: Molecular Mediators and Their Pharmacological Modulation for the Maintenance of Metabolic Flexibility in Aging
    Tero-Vescan, Amelia, Degens, Hans, Matsakas, Antonios, Ștefănescu, Ruxandra, Ősz, Bianca Eugenia, Slevin, Mark · 2025 · Pharmaceuticals
55. Targeting inflammation through a physical active lifestyle and pharmaceuticals for the treatment of type 2 diabetes
    Knudsen, Sine Haugaard, Pedersen, Bente Klarlund · 2015 · Current Diabetes Reports
56. Transcriptional network analysis in muscle reveals AP-1 as a partner of PGC-1α in the regulation of the hypoxic gene program
    Baresic, Mario, Salatino, Silvia, Kupr, Barbara, van Nimwegen, Erik, Handschin, Christoph · 2014 · Molecular and Cellular Biology
57. Who would have thought—Myokines two decades on
    Febbraio, Mark A., Pedersen, Bente K. · 2020 · Nature Reviews Endocrinology
58. PGC-1α–FNDC5–BDNF signaling pathway in skeletal muscle confers resilience to stress in mice subjected to chronic social defeat
    Zhan, Gaofeng, Huang, Niannian, Li, Shan, Hua, Dongyu, Zhang, Jie, Fang, Xi, Yang, Ning, Luo, Ailin, Yang, Chun · 2018 · Psychopharmacology
59. Research progress on sarcopenia in the musculoskeletal system
    Mao, Xinning, Lv, Ke, Qi, Weihui, Cheng, Wenqiang, Li, Tenghui, Sun, Yueli, Jin, Hongting, Pan, Hao, Wang, Dong · 2025 · Bone Research
60. Apelin/APJ system: A novel therapeutic target for locomotor system diseases
    Luo, Jingshun, Liu, Wei, Feng, Fen, Chen, Linxi · 2021 · European Journal of Pharmacology
61. The Effect of 12 Weeks of Different Exercise Training Modalities or Nutritional Guidance on Cardiometabolic Risk Factors, Vascular Parameters, and Physical Fitness in Overweight Adults: Cardiometabolic High-Intensity Interval Training-Resistance Training Randomized Controlled Study
    Ramírez-Vélez, Robinson, Castro-Astudillo, Karem, Correa-Bautista, Jorge Enrique, González-Ruíz, Katherine, Izquierdo, Mikel, García-Hermoso, Antonio, Álvarez, Cristian, Ramírez-Campillo, Rodrigo, Correa-Rodríguez, María · 2020 · Journal of Strength and Conditioning Research
62. Exercise-induced benefits on glucose handling in a model of diet-induced obesity are reduced by concurrent nicotinamide mononucleotide
    Yu, Josephine, Laybutt, David Ross, Kim, Lynn-Jee, Quek, Lake-Ee, Wu, Lindsay E., Morris, Margaret J., Youngson, Neil A. · 2021 · American Journal of Physiology-Endocrinology and Metabolism
63. The emerging role of skeletal muscle as a modulator of lipid profile the role of exercise and nutrition
    Nomikos, Tzortzis, Methenitis, Spyridon, Panagiotakos, Demosthenes B · 2022 · Lipids in Health and Disease
64. Beta-Aminoisobutyric Acid Inhibits Hypothalamic Inflammation by Reversing Microglia Activation
    Park, Byong Seo, Tu, Thai Hien, Lee, Hannah, Jeong, Da Yeon, Yang, Sunggu, Lee, Byung Ju, Kim, Jae Geun · 2019 · Cells
65. Plasma apelin levels in overweight/obese adults following a single bout of exhaustive exercise: A preliminary cross-sectional study
    Son, Jun Seok, Chae, Song Ah, Park, Byung Ik, Du, Min, Song, Wook · 2019 · Endocrinología, Diabetes y Nutrición
66. The role of the androgen receptor in the pathogenesis of obesity and its utility as a target for obesity treatments
    Venkatesh, Varun S., Grossmann, Mathis, Zajac, Jeffrey D., Davey, Rachel A. · 2022 · Obesity Reviews
67. Moderators of resistance training effects in overweight and obese adults: a systematic review and meta-analysis
    LOPEZ, PEDRO, RADAELLI, RÉGIS, TAAFFE, DENNIS R., GALVÃO, DANIEL A., NEWTON, ROBERT U., NONEMACHER, ELISA R., WENDT, VICTÓRIA M., BASSANESI, RENATA N., TURELLA, DOUGLAS J. P., RECH, ANDERSON · 2022 · Medicine &amp; Science in Sports &amp; Exercise
68. Adiponectin in Myopathies
    Gamberi, Tania, Magherini, Francesca, Fiaschi, Tania · 2019 · International Journal of Molecular Sciences
69. Beneficial effect of exercise on cognitive function during peripheral arterial disease: potential involvement of myokines and microglial anti-inflammatory phenotype enhancement
    Leardini-Tristao, Marina, Charles, Anne-Laure, Lejay, Anne, Pizzimenti, Mégane, Meyer, Alain, Estato, Vanessa, Tibiriçá, Eduardo, Andres, Emmanuel, Geny, Bernard · 2019 · Journal of Clinical Medicine
70. Efficacy of Power Training on Sarcopenic Obesity in Community-Dwelling Older Women: A 32-Week Randomized Clinical Trial
    Polo-Ferrero, Luis, Martin, Maria J., Puente-González, Ana Silvia, Barbero-Iglesias, Fausto J., González-Manzano, Susana, Méndez-Sánchez, Roberto · 2025 · Nutrients
71. Small peptides: Could they have a big role in metabolism and the response to exercise?
    Atakan, Muhammed M., Türkel, İbrahim, Özerkliğ, Berkay, Koşar, Şükran N., Taylor, Dale F., Yan, Xu, Bishop, David J. · 2024 · The Journal of Physiology
72. Involvement of oxidative stress in atherosclerosis development in subjects with sarcopenic obesity: Oxidative stress with sarcopenic obesity
    Nakano, R., Takebe, N., Ono, M., Hangai, M., Nakagawa, R., Yashiro, S., Murai, T., Nagasawa, K., Takahashi, Y., Satoh, J. et al. · 2017 · Obesity Science &amp; Practice
73. Improving Obesity and Insulin Resistance by Targeting Skeletal Muscle MKP-1
    2020 · Journal of Cellular Signaling
74. Effects of Myostatin Gene Knockout on White Fat Browning and Related Gene Expression in Type 2 Diabetic Mice
    Cheng, Jingwei, Lee, Jaewoo, Liu, Yangqing, Wang, Yanfang, Duan, Mingtao, Zeng, Zhen · 2023 · Advances in Clinical and Experimental Medicine
75. Exercise-Induced Myokines in Obesity-Related Metabolic Disorders and Cardiovascular Protection: A Narrative Review
    Zhang, Yuxuan, Qiu, Yajun · 2026 · Sports
76. Ribosome Biogenesis as a Putative Bottleneck to Skeletal Muscle Hypertrophy: Mechanisms, Human Evidence, and Practical Modulators
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