The Effect of Retarded Growth Upon the Length of Life Span and Upon the Ultimate Body Size

THE RESUMPTION OF GROWTH AFTER LONG CONTINUED FAILURE TO GROW

Osborne, T. B., Mendel, L. B., Ferry, E. L., et al. (1915) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)87585-8 · Cited by 108

Cellulose in the Diet of Rats and Mice

McCay, C. M., Ku, C. C., Woodward, J. C., et al. (1934) · Journal of Nutrition · doi:10.1093/jn/8.4.435 · Cited by 23

The Interrelations of Various Probability Tables and a Modification of Student's Probability Table for the Argument “t”1

Livermore, J. R. (1934) · Agronomy Journal · doi:10.2134/agronj1934.00021962002600080006x · Cited by 4

Reactive Oxygen Species, Toxicity, Oxidative Stress, and Antioxidants: Chronic Diseases and Aging

Jomova, K., Raptova, R., Alomar, S. Y., Alwasel, S. H., Nepovimova, E., Kuca, K., & Valko, M. (2023) · Archives of Toxicology · doi:10.1007/s00204-023-03562-9 · Cited by 2,638

Caloric Restriction Delays Disease Onset and Mortality in Rhesus Monkeys

Colman, R. J., Anderson, R. M., Johnson, S. C., Kastman, E. K., Kosmatka, K. J., Beasley, T. M., Allison, D. B., Cruzen, C., Simmons, H. A., Kemnitz, J. W., et al. (2009) · Science · doi:10.1126/science.1173635 · Cited by 2,277

Ageing as a Risk Factor for Disease

Niccoli, T., & Partridge, L. (2012) · Current Biology · doi:10.1016/j.cub.2012.07.024 · Cited by 1,831

The intersection between aging and cardiovascular disease

North, B. J., & Sinclair, D. A. (2012) · Circulation Research · doi:10.1161/circresaha.111.246876 · Cited by 1,585

Calorie Restriction-like Effects of 30 Days of Resveratrol Supplementation on Energy Metabolism and Metabolic Profile in Obese Humans

Timmers, S., Konings, E., Bilet, L., Houtkooper, R. H., van de Weijer, T., Goossens, G. H., Hoeks, J., van der Krieken, S., Ryu, D., Kersten, S., et al. (2011) · Cell Metabolism · doi:10.1016/j.cmet.2011.10.002 · Cited by 1,320

Sestrin2 is a leucine sensor for the mTORC1 pathway

Wolfson, R. L., Chantranupong, L., Saxton, R. A., Shen, K., Scaria, S. M., Cantor, J. R., & Sabatini, D. M. (2016) · Science · doi:10.1126/science.aab2674 · Cited by 1,306

Mammalian sirtuins—emerging roles in physiology, aging, and calorie restriction

Haigis, M. C., & Guarente, L. P. (2006) · Genes & Development · doi:10.1101/gad.1467506 · Cited by 1,295

Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span

Pearson, K. J., Baur, J. A., Lewis, K. N., Peshkin, L., Price, N. L., Labinskyy, N., Swindell, W. R., Kamara, D., Minor, R. K., Perez, E., et al. (2008) · Cell Metabolism · doi:10.1016/j.cmet.2008.06.011 · Cited by 1,162

Epigenetic mechanisms of longevity and aging

Sen, P., Shah, P. P., Nativio, R., & Berger, S. L. (2016) · Cell · doi:10.1016/j.cell.2016.07.050 · Cited by 956

Effect of 6-Month Calorie Restriction on Biomarkers of Longevity, Metabolic Adaptation, and Oxidative Stress in Overweight Individuals: A Randomized Controlled Trial

Heilbronn, L. K., de Jonge, L., Frisard, M. I., DeLany, J. P., Larson-Meyer, D. E., Rood, J., Nguyen, T., Martin, C. K., Volaufova, J., Most, M. M., et al. (2006) · JAMA · doi:10.1001/jama.295.13.1539 · Cited by 969

Slowing ageing by design: the rise of NAD+ and sirtuin-activating compounds

Bonkowski, M. S., & Sinclair, D. A. (2016) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm.2016.93 · Cited by 834

Calorie restriction–the SIR2 connection

Guarente, L., & Picard, F. (2005) · Cell · doi:10.1016/j.cell.2005.01.029 · Cited by 793

How increased oxidative stress promotes longevity and metabolic health: The concept of mitochondrial hormesis (mitohormesis)

Ristow, M., & Zarse, K. (2010) · Experimental Gerontology · doi:10.1016/j.exger.2010.03.014 · Cited by 789

Oxidative damage, mitochondrial oxidant generation and antioxidant defenses during aging and in response to food restriction in the mouse

Sohal, R. S., Ku, H.-H., Agarwal, S., Forster, M. J., & Lal, H. (1994) · Mechanisms of Ageing and Development · doi:10.1016/0047-6374(94)90104-x · Cited by 788

Nicotinic Acid, Nicotinamide, and Nicotinamide Riboside: A Molecular Evaluation of NAD + Precursor Vitamins in Human Nutrition

Bogan, K. L., & Brenner, C. (2008) · Annual Review of Nutrition · doi:10.1146/annurev.nutr.28.061807.155443 · Cited by 707

Sirt1 Regulates Insulin Secretion by Repressing UCP2 in Pancreatic β Cells

Bordone, L., Motta, M. C., Picard, F., Robinson, A., Jhala, U. S., Apfeld, J., McDonagh, T., Lemieux, M., McBurney, M., Szilvasi, A., et al. (2005) · PLoS Biology · doi:10.1371/journal.pbio.0040031 · Cited by 715

Calorie restriction and aging: review of the literature and implications for studies in humans

Heilbronn, L. K., & Ravussin, E. (2003) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/78.3.361 · Cited by 701

Caloric restriction and aging: an update

Masoro, E. J. (2000) · Experimental Gerontology · doi:10.1016/s0531-5565(00)00084-x · Cited by 615

The GH/IGF-1 axis in ageing and longevity

Junnila, R. K., List, E. O., Berryman, D. E., Murrey, J. W., & Kopchick, J. J. (2013) · Nature Reviews Endocrinology · doi:10.1038/nrendo.2013.67 · Cited by 574

Sexual Differentiation, Pregnancy, Calorie Restriction, and Aging Affect the Adipocyte-Specific Secretory Protein Adiponectin

Combs, T. P., Berg, A. H., Rajala, M. W., Klebanov, S., Iyengar, P., Jimenez-Chillaron, J. C., Patti, M. E., Klein, S. L., Weinstein, R. S., & Scherer, P. E. (2003) · Diabetes · doi:10.2337/diabetes.52.2.268 · Cited by 544

Aging, adiposity, and calorie restriction

Fontana, L. (2007) · JAMA · doi:10.1001/jama.297.9.986 · Cited by 526

Mitohormesis: Promoting Health and Lifespan by Increased Levels of Reactive Oxygen Species (ROS)

Ristow, M., & Schmeisser, K. (2014) · Dose-Response · doi:10.2203/dose-response.13-035.ristow · Cited by 534

Genetic variation in the murine lifespan response to dietary restriction: from life extension to life shortening

Liao, C., Rikke, B. A., Johnson, T. E., Diaz, V., & Nelson, J. F. (2010) · Aging Cell · doi:10.1111/j.1474-9726.2009.00533.x · Cited by 501

The molecular targets of resveratrol

Kulkarni, S. S., & Cantó, C. (2015) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2014.10.005 · Cited by 477

Calorie restriction and sirtuins revisited

Guarente, L. (2013) · Genes & Development · doi:10.1101/gad.227439.113 · Cited by 464

Tumours with PI3K activation are resistant to dietary restriction

Kalaany, N. Y., & Sabatini, D. M. (2009) · Nature · doi:10.1038/nature07782 · Cited by 468

Effects of Sex, Strain, and Energy Intake on Hallmarks of Aging in Mice

Mitchell, S. J., Madrigal-Matute, J., Scheibye-Knudsen, M., Fang, E., Aon, M., González-Reyes, J. A., Cortassa, S., Kaushik, S., Gonzalez-Freire, M., Patel, B., et al. (2016) · Cell Metabolism · doi:10.1016/j.cmet.2016.05.027 · Cited by 451

Ageing and rejuvenation of tissue stem cells and their niches

Brunet, A., Goodell, M. A., & Rando, T. A. (2023) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-022-00510-w · Cited by 407

Caloric restriction, SIRT1 and longevity

Cantó, C., & Auwerx, J. (2009) · Trends in Endocrinology & Metabolism · doi:10.1016/j.tem.2009.03.008 · Cited by 395

Transgenic Mice with a Reduced Core Body Temperature Have an Increased Life Span

Conti, B., Sanchez-Alavez, M., Winsky-Sommerer, R., Morale, M. C., Lucero, J., Brownell, S., Fabre, V., Huitron-Resendiz, S., Henriksen, S., Zorrilla, E. P., et al. (2006) · Science · doi:10.1126/science.1132191 · Cited by 392

Progeria syndromes and ageing: what is the connection?

Burtner, C. R., & Kennedy, B. K. (2010) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2944 · Cited by 386

Caloric Restriction, the Traditional Okinawan Diet, and Healthy Aging: The Diet of the World's Longest‐Lived People and Its Potential Impact on Morbidity and Life Span

WILLCOX, B. J., WILLCOX, D. C., TODORIKI, H., FUJIYOSHI, A., YANO, K., HE, Q., CURB, J. D., & SUZUKI, M. (2007) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1396.037 · Cited by 370

DNA damage and ageing: new-age ideas for an age-old problem

Garinis, G. A., van der Horst, G. T. J., Vijg, J., & H.J. Hoeijmakers, J. (2008) · Nature Cell Biology · doi:10.1038/ncb1108-1241 · Cited by 366

Retarded Growth, Life Span, Ultimate Body Size and Age Changes in the Albino Rat after Feeding Diets Restricted in Calories

McCay, C. M., Maynard, L. A., Sperling, G., & Barnes, L. L. (1939) · The Journal of Nutrition · doi:10.1093/jn/18.1.1 · Cited by 362

“Control” laboratory rodents are metabolically morbid: Why it matters

Martin, B., Ji, S., Maudsley, S., & Mattson, M. P. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0912955107 · Cited by 354

Caloric Restriction Reprograms the Single-Cell Transcriptional Landscape of Rattus Norvegicus Aging

Ma, S., Sun, S., Geng, L., Song, M., Wang, W., Ye, Y., Ji, Q., Zou, Z., Wang, S., He, X., et al. (2020) · Cell · doi:10.1016/j.cell.2020.02.008 · Cited by 349

Animal models of aging research: implications for human aging and age-related diseases

Mitchell, S. J., Scheibye-Knudsen, M., Longo, D. L., & de Cabo, R. (2015) · Annual Review of Animal Biosciences · doi:10.1146/annurev-animal-022114-110829 · Cited by 328

Of mice and men: the benefits of caloric restriction, exercise, and mimetics

Mercken, E. M., Carboneau, B. A., Krzysik-Walker, S. M., & de Cabo, R. (2012) · Ageing Research Reviews · doi:10.1016/j.arr.2011.11.005 · Cited by 318

Systematic review and meta‐analysis of clinical trials of the effects of low carbohydrate diets on cardiovascular risk factors

Santos, F. L., Esteves, S. S., da Costa Pereira, A., Yancy Jr, W. S., & Nunes, J. P. L. (2012) · Obesity Reviews · doi:10.1111/j.1467-789x.2012.01021.x · Cited by 318

SIRT6 protects against pathological damage caused by diet‐induced obesity

Kanfi, Y., Peshti, V., Gil, R., Naiman, S., Nahum, L., Levin, E., Kronfeld‐Schor, N., & Cohen, H. Y. (2010) · Aging Cell · doi:10.1111/j.1474-9726.2009.00544.x · Cited by 311

Molecular mechanisms linking calorie restriction and longevity

Merry, B. J. (2002) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/s1357-2725(02)00038-9 · Cited by 304

Revenge of the “Sit”: How lifestyle impacts neuronal and cognitive health through molecular systems that interface energy metabolism with neuronal plasticity

Vaynman, S., & Gomez‐Pinilla, F. (2006) · Journal of Neuroscience Research · doi:10.1002/jnr.20979 · Cited by 299

Calorie restriction and prevention of age‐associated chronic disease

Omodei, D., & Fontana, L. (2011) · FEBS Letters · doi:10.1016/j.febslet.2011.03.015 · Cited by 293

Effects of intermittent feeding upon body weight and lifespan in inbred mice: interaction of genotype and age

Goodrick, C. L., Ingram, D. K., Reynolds, M. A., Freeman, J. R., & Cider, N. (1990) · Mechanisms of Ageing and Development · doi:10.1016/0047-6374(90)90107-q · Cited by 279

Caloric Restriction and Aging: Studies in Mice and Monkeys

Anderson, R. M., Shanmuganayagam, D., & Weindruch, R. (2009) · Toxicologic Pathology · doi:10.1177/0192623308329476 · Cited by 276

Aging Hallmarks and Progression and Age-Related Diseases: A Landscape View of Research Advancement

Tenchov, R., Sasso, J. M., Wang, X., & Zhou, Q. A. (2024) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.3c00531 · Cited by 276

Obesity May Accelerate the Aging Process

Salvestrini, V., Sell, C., & Lorenzini, A. (2019) · Frontiers in Endocrinology · doi:10.3389/fendo.2019.00266 · Cited by 260

Macronutrient balance, reproductive function, and lifespan in aging mice

Solon-Biet, S. M., Walters, K. A., Simanainen, U. K., McMahon, A. C., Ruohonen, K., Ballard, J. W. O., Raubenheimer, D., Handelsman, D. J., Le Couteur, D. G., & Simpson, S. J. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1422041112 · Cited by 243

Radical medicine: treating ageing to cure disease

Finkel, T. (2005) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1763 · Cited by 234

SIRT1 promotes the central adaptive response to diet restriction through activation of the dorsomedial and lateral nuclei of the hypothalamus

Satoh, A., Brace, C. S., Ben-Josef, G., West, T., Wozniak, D. F., Holtzman, D. M., Herzog, E. D., & Imai, S.-I. (2010) · The Journal of Neuroscience · doi:10.1523/jneurosci.1385-10.2010 · Cited by 237

The impact of low-protein high-carbohydrate diets on aging and lifespan

Le Couteur, D. G., Solon-Biet, S., Cogger, V. C., Mitchell, S. J., Senior, A., de Cabo, R., Raubenheimer, D., & Simpson, S. J. (2016) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-015-2120-y · Cited by 209

Dietary Protein to Carbohydrate Ratio and Caloric Restriction: Comparing Metabolic Outcomes in Mice

Solon-Biet, S. M., Mitchell, S. J., Coogan, S. C. P., Cogger, V. C., Gokarn, R., McMahon, A. C., Raubenheimer, D., de Cabo, R., Simpson, S. J., & Le Couteur, D. G. (2015) · Cell Reports · doi:10.1016/j.celrep.2015.05.007 · Cited by 207

The coordination of nuclear and mitochondrial communication during aging and calorie restriction

Finley, L. W. S., & Haigis, M. C. (2009) · Ageing Research Reviews · doi:10.1016/j.arr.2009.03.003 · Cited by 207

The dorsal raphe nucleus and serotonin: implications for neuroplasticity linked to major depression and Alzheimer's disease

MICHELSEN, K., PRICKAERTS, J., & STEINBUSCH, H. (2008) · Progress in Brain Research · doi:10.1016/s0079-6123(08)00912-6 · Cited by 196

Resveratrol as a calorie restriction mimetic: therapeutic implications

Chung, J. H., Manganiello, V., & Dyck, J. R. B. (2012) · Trends in Cell Biology · doi:10.1016/j.tcb.2012.07.004 · Cited by 192

NAD + metabolism: A therapeutic target for age-related metabolic disease

Mouchiroud, L., Houtkooper, R. H., & Auwerx, J. (2013) · Critical Reviews in Biochemistry and Molecular Biology · doi:10.3109/10409238.2013.789479 · Cited by 193

SIRT3 regulates mitochondrial protein acetylation and intermediary metabolism

Hirschey, M. D., Shimazu, T., Huang, J. Y., Schwer, B., & Verdin, E. (2011) · Cold Spring Harbor Symposia on Quantitative Biology · doi:10.1101/sqb.2011.76.010850 · Cited by 180

Dietary protein, aging and nutritional geometry

Simpson, S. J., Le Couteur, D. G., Raubenheimer, D., Solon-Biet, S. M., Cooney, G. J., Cogger, V. C., & Fontana, L. (2017) · Ageing Research Reviews · doi:10.1016/j.arr.2017.03.001 · Cited by 169

Long-term caloric restriction increases UCP3 content but decreases proton leak and reactive oxygen species production in rat skeletal muscle mitochondria

Bevilacqua, L., Ramsey, J. J., Hagopian, K., Weindruch, R., & Harper, M.-E. (2005) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00435.2004 · Cited by 172

Molecular mechanisms of brain aging and neurodegenerative disorders: Lessons from dietary restriction

Prolla, T. A., & Mattson, M. P. (2001) · Trends in Neurosciences · doi:10.1016/s0166-2236(00)01957-3 · Cited by 159

Metformin Supplementation and Life Span in Fischer-344 Rats

Smith, D. L., Elam, C. F., Mattison, J. A., Lane, M. A., Roth, G. S., Ingram, D. K., & Allison, D. B. (2010) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/glq033 · Cited by 153

Calcium signaling alterations, oxidative stress, and autophagy in aging

Ureshino, R. P., Rocha, K. K., Lopes, G. S., Bincoletto, C., & Smaili, S. S. (2014) · Antioxidants & Redox Signaling · doi:10.1089/ars.2013.5777 · Cited by 143

Aging and Caloric Restriction Research: A Biological Perspective with Translational Potential

Balasubramanian, P., Howell, P. R., & Anderson, R. M. (2017) · EBioMedicine · doi:10.1016/j.ebiom.2017.06.015 · Cited by 148

Heart rate, lifespan, and mortality risk

Zhang, G. Q., & Zhang, W. (2009) · Ageing Research Reviews · doi:10.1016/j.arr.2008.10.001 · Cited by 139

Genetic differences in effects of food restriction on aging in mice

Harrison, D. E., & Archer, J. R. (1987) · The Journal of Nutrition · doi:10.1093/jn/117.2.376 · Cited by 133

Calories or protein? The effect of dietary restriction on lifespan in rodents is explained by calories alone

Speakman, J. R., Mitchell, S. E., & Mazidi, M. (2016) · Experimental Gerontology · doi:10.1016/j.exger.2016.03.011 · Cited by 131

Fat maintenance is a predictor of the murine lifespan response to dietary restriction

Liao, C., Rikke, B. A., Johnson, T. E., Gelfond, J. A. L., Diaz, V., & Nelson, J. F. (2011) · Aging Cell · doi:10.1111/j.1474-9726.2011.00702.x · Cited by 120

Mouse Models to Disentangle the Hallmarks of Human Aging

Folgueras, A. R., Freitas-Rodríguez, S., Velasco, G., & López-Otín, C. (2018) · Circulation Research · doi:10.1161/circresaha.118.312204 · Cited by 113

Caloric restriction: Beneficial effects on brain aging and Alzheimer’s disease

Van Cauwenberghe, C., Vandendriessche, C., Libert, C., & Vandenbroucke, R. E. (2016) · Mammalian Genome · doi:10.1007/s00335-016-9647-6 · Cited by 121

Caloric restriction and its mimetics

Lee, S.-H., & Min, K.-J. (2013) · BMB Reports · doi:10.5483/bmbrep.2013.46.4.033 · Cited by 119

The role of estrogen deficiency in skin ageing and wound healing

Emmerson, E., & Hardman, M. J. (2012) · Biogerontology · doi:10.1007/s10522-011-9322-y · Cited by 118

Caloric restriction blocks neuropathology and motor deficits in Machado-Joseph disease mouse models through SIRT1 pathway

Cunha-Santos, J., Duarte-Neves, J., Carmona, V., Guarente, L., Pereira de Almeida, L., & Cavadas, C. (2016) · Nature Communications · doi:10.1038/ncomms11445 · Cited by 109

Telomerase Reverse Transcriptase Synergizes with Calorie Restriction to Increase Health Span and Extend Mouse Longevity

Vera, E., Bernardes de Jesus, B., Foronda, M., Flores, J. M., & Blasco, M. A. (2013) · PLoS ONE · doi:10.1371/journal.pone.0053760 · Cited by 111

Recent advances in calorie restriction research on aging

Chung, K. W., Kim, D. H., Park, M. H., Choi, Y. J., Kim, N. D., Lee, J., Yu, B. P., & Chung, H. Y. (2013) · Experimental Gerontology · doi:10.1016/j.exger.2012.11.007 · Cited by 108

Metabolic effects of resveratrol: Addressing the controversies

Bitterman, J. L., & Chung, J. H. (2015) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-014-1808-8 · Cited by 109

Life Span Is Prolonged in Food-Restricted Autoimmune-Prone (NZB × NZW)F(1) Mice Fed a Diet Enriched with (n-3) Fatty Acids

Jolly, C. A., Muthukumar, A., Avula, C. P. R., Fernandes, G., & Troyer, D. (2001) · The Journal of Nutrition · doi:10.1093/jn/131.10.2753 · Cited by 104

Chronobiology of Aging: A Mini-Review

Cornelissen, G., & Otsuka, K. (2017) · Gerontology · doi:10.1159/000450945 · Cited by 96

Cell culture-based profiling across mammals reveals DNA repair and metabolism as determinants of species longevity

Ma, S., Upneja, A., Galecki, A., Tsai, Y.-M., Burant, C. F., Raskind, S., Zhang, Q., Zhang, Z. D., Seluanov, A., Gorbunova, V., et al. (2016) · eLife · doi:10.7554/elife.19130 · Cited by 89

Impact of age, caloric restriction, and influenza infection on mouse gut microbiome: an exploratory study of the role of age-related microbiome changes on influenza responses

Bartley, J. M., Zhou, X., Kuchel, G. A., Weinstock, G. M., & Haynes, L. (2017) · Frontiers in Immunology · doi:10.3389/fimmu.2017.01164 · Cited by 87

Housing Density Does Not Influence the Longevity Effect of Calorie Restriction

Ikeno, Y., Hubbard, G. B., Lee, S., Richardson, A., Strong, R., Diaz, V., & Nelson, J. F. (2005) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/60.12.1510 · Cited by 83

Intermittent fasting versus continuous energy-restricted diet for patients with type 2 diabetes mellitus and metabolic syndrome for glycemic control: a systematic review and meta-analysis of randomized controlled trials

Wang, X., Li, Q., Liu, Y., Jiang, H., & Chen, W. (2021) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2021.109003 · Cited by 79

Fasting induces a highly resilient deep quiescent state in muscle stem cells via ketone body signaling

Benjamin, D. I., Both, P., Benjamin, J. S., Nutter, C. W., Tan, J. H., Kang, J., Machado, L. A., Klein, J. D. D., de Morree, A., Kim, S., et al. (2022) · Cell Metabolism · doi:10.1016/j.cmet.2022.04.012 · Cited by 79

The effects of age and systemic metabolism on anti-tumor T cell responses

Drijvers, J. M., Sharpe, A. H., & Haigis, M. C. (2020) · eLife · doi:10.7554/elife.62420 · Cited by 69

Adipokines and Aging: Findings From Centenarians and the Very Old

Arai, Y., Kamide, K., & Hirose, N. (2019) · Frontiers in Endocrinology · doi:10.3389/fendo.2019.00142 · Cited by 71

Honoring Clive McCay and 75 Years of Calorie Restriction Research ,

McDonald, R. B., & Ramsey, J. J. (2010) · The Journal of Nutrition · doi:10.3945/jn.110.122804 · Cited by 68

The role of insulin and insulin-like growth factor-I in mammalian ageing

Richardson, A., Liu, F., Adamo, M. L., Remmen, H. V., & Nelson, J. F. (2004) · Best Practice & Research Clinical Endocrinology & Metabolism · doi:10.1016/j.beem.2004.02.002 · Cited by 64

Calorie restriction in overweight males ameliorates obesity-related metabolic alterations and cellular adaptations through anti-aging effects, possibly including AMPK and SIRT1 activation

Kitada, M., Kume, S., Takeda-Watanabe, A., Tsuda, S.-I., Kanasaki, K., & Koya, D. (2013) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2013.06.014 · Cited by 60

Oxidative stress, antioxidants, hormesis and calorie restriction: The current perspective in the biology of aging

Mehdi, M. M., Solanki, P., & Singh, P. (2021) · Archives of Gerontology and Geriatrics · doi:10.1016/j.archger.2021.104413 · Cited by 54

Open-minded scepticism: inferring the causal mechanisms of human ageing from genetic perturbations

de Magalhães, J. P. (2005) · Ageing Research Reviews · doi:10.1016/j.arr.2004.05.003 · Cited by 54

Endocrine alterations in response to calorie restriction in humans

Redman, L. M., & Ravussin, E. (2009) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2008.10.014 · Cited by 54

Dietary Restriction and Neuroinflammation: A Potential Mechanistic Link

Bok, E., Jo, M., Lee, S., Lee, B.-R., Kim, J., & Kim, H.-J. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20030464 · Cited by 53

DNA damage in aging, the stem cell perspective

McNeely, T., Leone, M., Yanai, H., & Beerman, I. (2020) · Human Genetics · doi:10.1007/s00439-019-02047-z · Cited by 52

Bring Back the Rat!

Carter, C. S., Richardson, A., Huffman, D. M., & Austad, S. (2020) · The Journals of Gerontology: Series A · doi:10.1093/gerona/glz298 · Cited by 51

Nutrition modulation of human aging: The calorie restriction paradigm

Das, S. K., Balasubramanian, P., & Weerasekara, Y. K. (2017) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2017.04.011 · Cited by 51

Reduced bone mineral density is not associated with significantly reduced bone quality in men and women practicing long‐term calorie restriction with adequate nutrition

Villareal, D. T., Kotyk, J. J., Armamento‐Villareal, R. C., Kenguva, V., Seaman, P., Shahar, A., Wald, M. J., Kleerekoper, M., & Fontana, L. (2011) · Aging Cell · doi:10.1111/j.1474-9726.2010.00643.x · Cited by 51

Systemic GDF11 stimulates the secretion of adiponectin and induces a calorie restriction‐like phenotype in aged mice

Katsimpardi, L., Kuperwasser, N., Camus, C., Moigneu, C., Chiche, A., Tolle, V., Li, H., Kokovay, E., & Lledo, P. (2020) · Aging Cell · doi:10.1111/acel.13038 · Cited by 47

The Geroscience Hypothesis: Is It Possible to Change the Rate of Aging?

Austad, S. N. (2016) · Advances in Geroscience · doi:10.1007/978-3-319-23246-1_1 · Cited by 43

Calorie restriction increases lipopolysaccharide-induced neuropeptide Y immunolabeling and reduces microglial cell area in the arcuate hypothalamic nucleus

Radler, M. E., Wright, B. J., Walker, F. R., Hale, M. W., & Kent, S. (2015) · Neuroscience · doi:10.1016/j.neuroscience.2014.11.014 · Cited by 31

Exercise and food restriction in rats

Holloszy, J. O. (1992) · The Journal of Nutrition · doi:10.1093/jn/122.suppl_3.774 · Cited by 30

Intermittent Fasting: Myths, Fakes and Truth on This Dietary Regimen Approach

Brogi, S., Tabanelli, R., Puca, S., & Calderone, V. (2024) · Foods · doi:10.3390/foods13131960 · Cited by 26

THE RELATIONSHIP BETWEEN AGE AT SEXUAL MATURITY AND SOME PRODUCTIVE TRAITS IN LOCAL CHICKENS STRAIN

Amira, E. E. (2008) · Cited by 13

Genetical studies on the skeleton of the mouse

Grüneberg, H. (1953) · Journal of Genetics · doi:10.1007/bf03023301 · Cited by 81

Rate of Renewal of the Fish Skeleton

HEVESY, G. (1945) · Acta Physiologica Scandinavica · doi:10.1111/j.1748-1716.1945.tb03100.x · Cited by 8

Relations between age at sexual maturity and some production characteristics in quails

Camcı, Ö., Erensayin, C., & Aktan, S. (2002) · Archiv für Geflügelkunde · doi:10.1016/s0003-9098(25)00146-8 · Cited by 18

[Skeletal characteristics of the hand in cervical cancer].

Kantin, A. V., Gabelov, A. A., Khachaturian, R. E., et al. (1978) · PubMed