Effects of the obese Gene Product on Body Weight Regulation in ob / ob Mice

Pelleymounter, Mary Ann, Cullen, Mary Jane, Baker, Mary Beth, Hecht, Randy, Winters, Dwight, Boone, Thomas, Collins, Frank·1995·Science

DOI 10.1126/science.7624776

Cited by (188)

Items 101–188 of 188

Sympathetic system activity in obesity and metabolic syndrome
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BROWN ADIPOSE TISSUE, β3-ADRENERGIC RECEPTORS, AND OBESITY
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Critical role of STAT3 in leptin's metabolic actions
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Huo, Lihong, Gamber, Kevin, Greeley, Sarah, Silva, Jose, Huntoon, Nicholas, Leng, Xing-Hong, Bjørbæk, Christian · 2009 · Cell Metabolism
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Simon, C., Gronfier, C., Schlienger, J. L., Brandenberger, G. · 1998 · The Journal of Clinical Endocrinology & Metabolism
Intracerebroventricular Leptin Regulates Hepatic but Not Peripheral Glucose Fluxes
Liu, LiSen, Karkanias, George B., Morales, Jose' C., Hawkins, Meredith, Barzilai, Nir, Wang, Jiali, Rossetti, Luciano · 1998 · Journal of Biological Chemistry
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Harris, Ruth B. S. · 2000 · Annual Review of Nutrition
Selective leptin resistance: a new concept in leptin physiology with cardiovascular implications
Mark, Allyn L., Correia, Marcelo L. G., Rahmouni, Kamal, Haynes, William G. · 2002 · Journal of Hypertension
The arcuate nucleus as a primary site of satiety effect of leptin in rats
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Leptin replacement alters brain response to food cues in genetically leptin-deficient adults.
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Leptin restores adult hippocampal neurogenesis in a chronic unpredictable stress model of depression and reverses glucocorticoid-induced inhibition of GSK-3β/β-catenin signaling
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Nonsense mutation of leptin receptor in the obese spontaneously hypertensive Koletsky rat
Takaya, Kazuhiko, Ogawa, Yoshihiro, Hiraoka, Junko, Hosoda, Kiminori, Yamori, Yukio, Nakao, Kazuwa, Koletsky, Richard J. · 1996 · Nature Genetics
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Tran, Le Trung, Park, Sohee, Kim, Seul Ki, Lee, Jin Sun, Kim, Ki Woo, Kwon, Obin · 2022 · Experimental & Molecular Medicine
Leptin Receptor Long-form Splice-variant Protein Expression in Neuron Cell Bodies of the Brain and Co-localization with Neuropeptide Y mRNA in the Arcuate Nucleus
Baskin, Denis G., Schwartz, Michael W., Seeley, Randy J., Woods, Stephen C., Porte, Daniel, Breininger, John F., Jonak, Zoë, Schaefer, Jonathan, Krouse, Michael, Burghardt, Charles et al. · 1999 · Journal of Histochemistry & Cytochemistry
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Havel, Peter J., Uriu-Hare, Janet Y., Liu, Tina, Stanhope, Kimber L., Stern, Judith S., Keen, Carl L., Ahrén, Bo · 1998 · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
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Leptin inhibits insulin gene transcription and reverses hyperinsulinemia in leptin-deficient ob/ob mice
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Hypoxia and Adipocyte Physiology: Implications for Adipose Tissue Dysfunction in Obesity
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Leptin Rapidly Lowers Food Intake and Elevates Metabolic Rates in Lean and ob/ob Mice ,
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Obesity-Induced Hypertension: New Concepts From the Emerging Biology of Obesity
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Myostatin, activin receptor IIb, and follistatin-like-3 gene expression are altered in adipose tissue and skeletal muscle of obese mice
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Peripheral metabolic actions of leptin
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Differential expression of mRNA for leptin receptor isoforms in the rat brain
Guan, Xiao-Ming, Hess, J.Fred, Yu, Hong, Hey, Patricia J, van der Ploeg, Lex H.T · 1997 · Molecular and Cellular Endocrinology
Leptin Treatment Rescues the Sterility of Genetically Obese ob/ob Males*
Mounzih, Khalid, Lu, Ronghua, Chehab, Farid F. · 1997 · Endocrinology
Genetic rescue of nonclassical ERα signaling normalizes energy balance in obese Erα-null mutant mice
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Children with classic congenital adrenal hyperplasia have elevated serum leptin concentrations and insulin resistance: potential clinical implications.
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Hyperinsulinemia: A cause of obesity?
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Adult Type 3 Adenylyl Cyclase–Deficient Mice Are Obese
Wang, Zhenshan, Li, Vicky, Chan, Guy C. K., Phan, Trongha, Nudelman, Aaron S., Xia, Zhengui, Storm, Daniel R. · 2009 · PLoS ONE
Arcuate Nucleus-Specific Leptin Receptor Gene Therapy Attenuates the Obesity Phenotype of Koletsky (fak/fak) Rats
Morton, Gregory J., Niswender, Kevin D., Rhodes, Christopher J., Myers, Martin G., Blevins, James E., Baskin, Denis G., Schwartz, Michael W. · 2003 · Endocrinology
Gene-Environment Interactions Controlling Energy and Glucose Homeostasis and the Developmental Origins of Obesity
Bouret, Sebastien, Levin, Barry E., Ozanne, Susan E. · 2015 · Physiological Reviews
Systemic Anti-TNFα Treatment Restores Diabetes-Impaired Skin Repair in ob/ob Mice by Inactivation of Macrophages
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Islet Amyloid Polypeptide (IAPP) Transgenic Rodents as Models for Type 2 Diabetes
Matveyenko, A. V., Butler, P. C. · 2006 · ILAR Journal
Serotonin and the regulation of mammalian energy balance
Donovan, Michael H., Tecott, Laurence H. · 2013 · Frontiers in Neuroscience
Region-Specific Reduction in Leptin-Induced Phosphorylation of Signal Transducer and Activator of Transcription-3 (STAT3) in the Rat Hypothalamus Is Associated with Leptin Resistance during Pregnancy
Ladyman, S. R., Grattan, D. R. · 2004 · Endocrinology
Effect of three treatment schedules of recombinant methionyl human leptin on body weight in obese adults: a randomized, placebo‐controlled trial
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FGF21 Promotes Metabolic Homeostasis via White Adipose and Leptin in Mice
Véniant, Murielle M., Hale, Clarence, Helmering, Joan, Chen, Michelle M., Stanislaus, Shanaka, Busby, Jim, Vonderfecht, Steven, Xu, Jing, Lloyd, David J. · 2012 · PLoS ONE
Enhanced Leptin-Stimulated Pi3k Activation in the CNS Promotes White Adipose Tissue Transdifferentiation
Plum, Leona, Rother, Eva, Münzberg, Heike, Wunderlich, F. Thomas, Morgan, Donald A., Hampel, Brigitte, Shanabrough, Marya, Janoschek, Ruth, Könner, A. Christine, Alber, Jens et al. · 2007 · Cell Metabolism
Putting desire on a budget: dopamine and energy expenditure, reconciling reward and resources
Beeler, Jeff A., Frazier, Cristianne R. M., Zhuang, Xiaoxi · 2012 · Frontiers in Integrative Neuroscience
Leptin Administration Favors Muscle Mass Accretion by Decreasing FoxO3a and Increasing PGC-1α in ob/ob Mice
Sáinz, Neira, Rodríguez, Amaia, Catalán, Victoria, Becerril, Sara, Ramírez, Beatriz, Gómez-Ambrosi, Javier, Frühbeck, Gema · 2009 · PLoS ONE
Dopamine is required for hyperphagia in Lepob/ob mice
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Effects of Exogenous Leptin on Satiety and Satiation in Patients with Lipodystrophy and Leptin Insufficiency
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Activation of Stat3 Signaling in AgRP Neurons Promotes Locomotor Activity
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Conditional viral tracing reveals that steroidogenic factor 1-positive neurons of the dorsomedial subdivision of the ventromedial hypothalamus project to autonomic centers of the hypothalamus and hindbrain
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Central leptin increases insulin sensitivity in streptozotocin-induced diabetic rats
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Fate of leptin after intracerebroventricular injection into the mouse brain
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Norepinephrine Is Required for Leptin Effects on Gene Expression in Brown and White Adipose Tissue1
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Synaptic Plasticity in Energy Balance Regulation
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Chronic Leptin Administration Decreases Fatty Acid Uptake and Fatty Acid Transporters in Rat Skeletal Muscle
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The relationship between the serum leptin concentrations of thyrotoxic patients during treatment and their total fat mass is different from that of normal subjects
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Leptin is suppressed during infusion of recombinant human insulin-like growth factor I (rhIGF I) in normal rats
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Leptin Deficiency Per Se Dictates Body Composition and Insulin Action in ob/ob Mice
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No Relationship Between Leptin and Cortisol in Obese Children and Adolescents
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