Cited by 10Nutrition and Health in AgingMuscle metabolism and nutritionMuscle Physiology and Disorders

Nutritional Approaches to Treating Sarcopenia

Paddon‐Jones, Douglas, van Loon, Luc·2012·Sarcopenia

Abstract

[Extract] The goal of this chapter is to explore the obstacles and opportunities for treating sarcopenia using a nutrition-focused approach. While it is clear that sarcopenia is the result of a complex interplay of various factors, in all cases, an adequate nutritional framework is the fundamental prerequisite for maintaining muscle mass, strength and ultimately functional capacity.

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Crossref · 10.1002/9781118338032.ch19

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132 of 132 references verified0 citation errors · 0 not checkable

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  • The per-meal anabolic threshold of dietary protein/amino acid intake is higher in older individuals (25 to 30 g protein per meal, containing about 2.5 to 2.8 g leucine) than in young adults.

    “The per-meal anabolic threshold of dietary protein/amino acid intake is higher in older individuals (ie, 25 to 30 g protein per meal, containing about 2.5 to 2.8 g leucine) in comparison with young adults.”
  • In the fed state, most researchers agree there is an impairment of the muscle protein anabolic response to meal intake in older adults, although some studies found no difference, especially with high amino acid or protein amounts.

    “In the fed state, however, most researchers now agree that there is an impairment of the muscle protein anabolic response to meal intake in older adults, 46,49,50 although some studies found no difference between older and younger adults, especially when high amounts of amino acids or proteins were administered.”
  • Paddon-Jones 2012 argue that while a modest increase in dietary protein beyond the recommended dietary allowance may be beneficial for some older adults (perhaps 1.0-1.3 g/kg per day), there is a greater need to specifically examine the quality and quantity of protein consumed with each meal.

    “Paddon-Jones 2012 50 1.0e1.3g/kg BW/d .we argue that while a modest increase in dietary protein beyond the RDA may be beneficial for some older adults (perhaps 1.0e1.3g/kg per day), there is a greater need to specifically examine the quality and quantity of protein consumed with each meal.”

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Authors
Paddon‐Jones, D., & van Loon, L.
Affiliations
The University of Texas Medical Branch at Galveston (US)
Venue
Sarcopenia
Publisher
Wiley
Published
2012-07-27
Pages
275-295
OpenAlex
W1901312211
Cited by
10
References
135
Citations by year
2026: 1 · 2025: 1 · 2021: 1 · 2020: 1 · 2019: 1 · 2018: 2 · 2017: 1 · 2014: 1 · 2013: 1
Type
other
Language
en
Open access
closed
Topics
  • Health Sciences › Medicine › Physiology › Nutrition and Health in Aging
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Muscle metabolism and nutrition
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Muscle Physiology and Disorders
Keywords
sarcopenia, dietary intervention, muscle mass, muscle strength, functional capacity

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