Cited by 293Neural and Behavioral Psychology StudiesAnxiety, Depression, Psychometrics, Treatment, Cognitive ProcessesDecision-Making and Behavioral Economics

Dysfunctions of decision‐making and cognitive control as transdiagnostic mechanisms of mental disorders: advances, gaps, and needs in current research

Open access
Goschke, Thomas·2014·International Journal of Methods in Psychiatric Research

Abstract

Disadvantageous decision-making and impaired volitional control over actions, thoughts, and emotions are characteristics of a wide range of mental disorders such as addiction, eating disorders, depression, and anxiety disorders and may reflect transdiagnostic core mechanisms and possibly vulnerability factors. Elucidating the underlying neurocognitive mechanisms is a precondition for moving from symptom-based to mechanism-based disorder classifications and ultimately mechanism-targeted interventions. However, despite substantial advances in basic research on decision-making and cognitive control, there are still profound gaps in our current understanding of dysfunctions of these processes in mental disorders. Central unresolved questions are: (i) to which degree such dysfunctions reflect transdiagnostic mechanisms or disorder-specific patterns of impairment; (ii) how phenotypical features of mental disorders relate to dysfunctional control parameter settings and aberrant interactions between large-scale brain systems involved in habit and reward-based learning, performance monitoring, emotion regulation, and cognitive control; (iii) whether cognitive control impairments are consequences or antecedent vulnerability factors of mental disorders; (iv) whether they reflect generalized competence impairments or context-specific performance failures; (v) whether not only impaired but also chronic over-control contributes to mental disorders. In the light of these gaps, needs for future research are: (i) an increased focus on basic cognitive-affective mechanisms underlying decision and control dysfunctions across disorders; (ii) longitudinal-prospective studies systematically incorporating theory-driven behavioural tasks and neuroimaging protocols to assess decision-making and control dysfunctions and aberrant interactions between underlying large-scale brain systems; (iii) use of latent-variable models of cognitive control rather than single tasks; (iv) increased focus on the interplay of implicit and explicit cognitive-affective processes; (v) stronger focus on computational models specifying neurocognitive mechanisms underlying phenotypical expressions of mental disorders.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1002/mpr.1410

Cites

154 of 154 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • Decision-making and learning impairments are core characteristics of a wide range of psychiatric disorders, including MDD, OCD, and schizophrenia, and are linked to their specific symptoms.

    “Decision-making and learning impairments are core characteristics of a wide range of psychiatric disorders — such as major depressive disorder (MDD), obsessive–compulsive disorder (OCD), and schizophrenia — and are linked to their specific symptoms.1–9”

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Cites

Flagged first, then by citations

Research works printed but not linked: 8

  1. In Wiers R.W., Stacy A.W. (eds) Handbook of implicit cognition and addiction, pp. 215-232, Thousand Oaks, CA, Sage Publications.
  2. Bolte A., Goschke T. (2010) Thinking and emotion: affective modulation of cognitive processing modes. In Glatzeder B., Goel V., Müller A.v. (eds) On Thinking, Vol. II: Towards a Theory of Thinking, Heidelberg, Springer.
  3. Hassin R.R., Ochsner K., Trope Y. (eds) Self control in society, mind, and brain, pp. 141-160, Oxford, Oxford University Press.
  4. Goschke T. (1996) Gedächtnis und emotion: affektive bedingungen des einprägens, behaltens und vergessens. In Albert D., Stapf K.-H. (eds) Enzyklopädie der Psychologie Serie II, Band 4: Gedächtnis, pp. 605-694, Göttingen, Hogrefe.
  5. Goschke T. (2013) Volition in action: intentions, control dilemmas and the dynamic regulation of intentional control. In Prinz W., Beisert A., Herwig A. (eds) Action Science: Foundations of an Emerging Discipline, Cambridge, MA, MIT Press.
  6. Grant J.E., Potenza M.N., Weinstein A., Gorelick D.A. (2010) Introduction to behavioral addic- tions. American Journal of Drug and Alcohol Abuse, 36(5), 233-241.
  7. Koechlin E., Summerfield C. (2007) An informa- tion theoretical approach to prefrontal execu- tive function. Trends in Cognitive Sciences, 11(6), 229-235.
  8. Robinson T.E., Berridge K.C. (2003) Addiction. Annual Review of Psychology, 54, 25-53.

Cited by

Sorted by citations

Authors
Goschke, T.
Affiliations
Technische Universität Dresden (DE)
Corresponding author
Goschke, Thomas
Venue
International Journal of Methods in Psychiatric Research
Publisher
Wiley
Published
2013-12-23
Volume
23
Issue
S1
Pages
41-57
ISSN
  • 1049-8931 (ISSN-L)
  • 1557-0657
OpenAlex
W1784610759
Cited by
293
References
154
Citations by year
2026: 15 · 2025: 30 · 2024: 31 · 2023: 24 · 2022: 35 · 2021: 21 · 2020: 31 · 2019: 19 · 2018: 19 · 2017: 15 · 2016: 20 · 2015: 18 · 2014: 9 · 2013: 3 · 2012: 1
FWCI
1.43
Type
journal article
Language
en
Open access
Locations
  • International Journal of Methods in Psychiatric Research (publishedVersion)
  • Europe PMC (PubMed Central) (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
  • Social Sciences › Decision Sciences › General Decision Sciences › Decision-Making and Behavioral Economics
Keywords
decision-making, cognitive control, transdiagnostic mechanisms, mental illness, addiction, eating disorders, depression, anxiety disorders, reward learning, performance monitoring, emotion regulation, overcontrol, vulnerability factors, computational model
MeSH terms
Mental Disorders, Cognition Disorders, Decision Making, Health Services Needs and Demand, Humans, Neuropsychological Tests, Mood Disorders, Biomedical Research

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review