Free radicals in biology and medicine

Decreased levels of glutathione, the major brain antioxidant, in post-mortem prefrontal cortex from patients with psychiatric disorders

Gawryluk, J. W., Wang, J.-F., Andreazza, A. C., Shao, L., & Young, L. T. (2011) · The International Journal of Neuropsychopharmacology · doi:10.1017/s1461145710000805 · Cited by 594

The Molecular Basis for Oxidative Stress-Induced Insulin Resistance

Evans, J. L., Maddux, B. A., & Goldfine, I. D. (2005) · Antioxidants & Redox Signaling · doi:10.1089/ars.2005.7.1040 · Cited by 587

C11-BODIPY581/591, an oxidation-sensitive fluorescent lipid peroxidation probe: (micro)spectroscopic characterization and validation of methodology

Drummen, G. P. C., van Liebergen, L. C. M., Op den Kamp, J. A. F., & Post, J. A. (2002) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(02)00848-1 · Cited by 594

Regulation of the hypothalamic corticotropin-releasing hormone neurosecretory system

Whitnall, M. H. (1993) · Progress in Neurobiology · doi:10.1016/0301-0082(93)90035-q · Cited by 582

Total phenols, ascorbic acid, β-carotene and lycopene in Portuguese wild edible mushrooms and their antioxidant activities

Barros, L., Ferreira, M.-J., Queirós, B., Ferreira, I. C. F. R., & Baptista, P. (2007) · Food Chemistry · doi:10.1016/j.foodchem.2006.07.038 · Cited by 586

Fenton Chemistry: An Introduction

Wardman, P., & Candeias, L. P. (1996) · Radiation Research · doi:10.2307/3579270 · Cited by 587

Iron Homeostasis, Oxidative Stress, and DNA Damage

Meneghini, R. (1997) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(97)00016-6 · Cited by 578

Intake of mercury from fish, lipid peroxidation, and the risk of myocardial infarction and coronary, cardiovascular, and any death in eastern Finnish men

Salonen, J. T., Seppänen, K., Nyyssönen, K., Korpela, H., Kauhanen, J., Kantola, M., Tuomilehto, J., Esterbauer, H., Tatzber, F., & Salonen, R. (1995) · Circulation · doi:10.1161/01.cir.91.3.645 · Cited by 578

Antioxidant Therapy in Acute Central Nervous System Injury: Current State

Gilgun-Sherki, Y., Rosenbaum, Z., Melamed, E., & Offen, D. (2002) · Pharmacological Reviews · doi:10.1124/pr.54.2.271 · Cited by 568

Nitrogen dioxide and carbonate radical anion: two emerging radicals in biology

Augusto, O., Bonini, M. G., Amanso, A. M., Linares, E., Santos, C. C. X., & De Menezes, S. L. (2002) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(02)00786-4 · Cited by 555

Iron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseases

Kell, D. B. (2009) · BMC Medical Genomics · doi:10.1186/1755-8794-2-2 · Cited by 554

Role of iron in carcinogenesis: cancer as a ferrotoxic disease

Toyokuni, S. (2009) · Cancer Science · doi:10.1111/j.1349-7006.2008.01001.x · Cited by 552

Chemical oxidation and DNA damage catalysed by inorganic sunscreen ingredients

Dunford, R., Salinaro, A., Cai, L., Serpone, N., Horikoshi, S., Hidaka, H., & Knowland, J. (1997) · FEBS Letters · doi:10.1016/s0014-5793(97)01356-2 · Cited by 540

Oxidative stress in cell culture: an under‐appreciated problem?

Halliwell, B. (2003) · FEBS Letters · doi:10.1016/s0014-5793(03)00235-7 · Cited by 534

Commentary: Vitamin C: Antioxidant or Pro-Oxidant In Vivo?

Halliwell, B. (1996) · Free Radical Research · doi:10.3109/10715769609149066 · Cited by 531

Markers of Oxidative Stress during Diabetes Mellitus

Tiwari, B. K., Pandey, K. B., Abidi, A. B., & Rizvi, S. I. (2013) · Journal of Biomarkers · doi:10.1155/2013/378790 · Cited by 517

Ergothioneine; antioxidant potential, physiological function and role in disease

Cheah, I. K., & Halliwell, B. (2012) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2011.09.017 · Cited by 514

Placental endoplasmic reticulum stress and oxidative stress in the pathophysiology of unexplained intrauterine growth restriction and early onset preeclampsia

Burton, G. J., Yung, H.-W., Cindrova-Davies, T., & Charnock-Jones, D. S. (2009) · Placenta · doi:10.1016/j.placenta.2008.11.003 · Cited by 502

Genetics of longevity in model organisms: debates and paradigm shifts

Gems, D., & Partridge, L. (2013) · Annual Review of Physiology · doi:10.1146/annurev-physiol-030212-183712 · Cited by 499

Inhibition of Mitochondrial Respiration

Pelicano, H., Feng, L., Zhou, Y., Carew, J. S., Hileman, E. O., Plunkett, W., Keating, M. J., & Huang, P. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m301546200 · Cited by 495

Nutritional and medical importance of gamma-linolenic acid

Horrobin, D. F. (1992) · Progress in Lipid Research · doi:10.1016/0163-7827(92)90008-7 · Cited by 488

Free radicals and phagocytic cells

Rosen, G. M., Pou, S., Ramos, C. L., Cohen, M. S., & Britigan, B. E. (1995) · The FASEB Journal · doi:10.1096/fasebj.9.2.7540156 · Cited by 478

The redox stress hypothesis of aging

Sohal, R. S., & Orr, W. C. (2012) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2011.10.445 · Cited by 473

Inhibitors of the quinone-binding site allow rapid superoxide production from mitochondrial nadh:Ubiquinone oxidoreductase (complex i)

Lambert, A. J., & Brand, M. D. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m406576200 · Cited by 480

The structure of human mitochondrial manganese superoxide dismutase reveals a novel tetrameric interface of two 4-helix bundles

Borgstahl, G. E. O., Parge, H. E., Hickey, M. J., Beyer, W. F., Hallewell, R. A., & Tainer, J. A. (1992) · Cell · doi:10.1016/0092-8674(92)90270-m · Cited by 472

Tissue-, substrate-, and site-specific characteristics of mitochondrial reactive oxygen species generation

Tahara, E. B., Navarete, F. D. T., & Kowaltowski, A. J. (2009) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2009.02.008 · Cited by 479

Superoxide production by NADH:ubiquinone oxidoreductase (complex I) depends on the pH gradient across the mitochondrial inner membrane

LAMBERT, A. J., & BRAND, M. D. (2004) · Biochemical Journal · doi:10.1042/bj20040485 · Cited by 470

Labile plasma iron in iron overload: redox activity and susceptibility to chelation

Esposito, B. P., Breuer, W., Sirankapracha, P., Pootrakul, P., Hershko, C., & Cabantchik, Z. I. (2003) · Blood · doi:10.1182/blood-2003-03-0807 · Cited by 475

Redox Reactions and Microbial Killing in the Neutrophil Phagosome

Winterbourn, C. C., & Kettle, A. J. (2013) · Antioxidants & Redox Signaling · doi:10.1089/ars.2012.4827 · Cited by 468

Molecular targets of oxidative stress

Avery, S. V. (2011) · Biochemical Journal · doi:10.1042/bj20101695 · Cited by 474

Iron-induced carcinogenesis: The role of redox regulation

Toyokuni, S. (1996) · Free Radical Biology and Medicine · doi:10.1016/0891-5849(95)02111-6 · Cited by 471

The wanderings of a free radical

Halliwell, B. (2009) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2008.11.008 · Cited by 467

Mutagenicity and repair of oxidative DNA damage: insights from studies using defined lesions

Wang, D., Kreutzer, D. A., & Essigmann, J. M. (1998) · Mutation research. Fundamental and molecular mechanisms of mutagenesis · doi:10.1016/s0027-5107(98)00066-9 · Cited by 464

Effect of a Traditional Mediterranean Diet on Lipoprotein Oxidation: A Randomized Controlled Trial

Fitó, M., Guxens, M., Corella, D., Sáez, G., Estruch, R., de la Torre, R., Francés, F., Cabezas, C., López-Sabater, M. D. C., Marrugat, J., et al. (2007) · Archives of Internal Medicine · doi:10.1001/archinte.167.11.1195 · Cited by 448

Hydroxyl‐radical production in physiological reactions: A novel function of peroxidase

Chen, S., & Schopfer, P. (1999) · European Journal of Biochemistry · doi:10.1046/j.1432-1327.1999.00199.x · Cited by 449

The Role of Oxidative Stress in the Pathophysiology of Gestational Diabetes Mellitus

Lappas, M., Hiden, U., Desoye, G., Froehlich, J., Mouzon, S. H.-D., & Jawerbaum, A. (2011) · Antioxidants & Redox Signaling · doi:10.1089/ars.2010.3765 · Cited by 442

Reactive Oxygen Species Are Signalling Molecules for Skeletal Muscle Adaptation

Powers, S. K., Duarte, J., Kavazis, A. N., & Talbert, E. E. (2010) · Experimental Physiology · doi:10.1113/expphysiol.2009.050526 · Cited by 440

Exercise-induced oxidative stress in humans: cause and consequences

Powers, S. K., Nelson, W. B., & Hudson, M. B. (2011) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2010.12.009 · Cited by 441

The role of free radicals in asbestos-induced diseases

Kamp, D. W., Graceffa, P., Pryor, W. A., & Weitzman, S. A. (1992) · Free Radical Biology and Medicine · doi:10.1016/0891-5849(92)90117-y · Cited by 428

The mitochondria-targeted antioxidant MitoQ prevents loss of spatial memory retention and early neuropathology in a transgenic mouse model of Alzheimer’s disease

McManus, M. J., Murphy, M. P., & Franklin, J. L. (2011) · The Journal of Neuroscience · doi:10.1523/jneurosci.0552-11.2011 · Cited by 432

Oxidative Stress in Developmental Origins of Disease: Teratogenesis, Neurodevelopmental Deficits, and Cancer

Wells, P. G., McCallum, G. P., Chen, C. S., Henderson, J. T., Lee, C. J. J., Perstin, J., Preston, T. J., Wiley, M. J., & Wong, A. W. (2009) · Toxicological Sciences · doi:10.1093/toxsci/kfn263 · Cited by 430

Against the oxidative damage theory of aging: superoxide dismutases protect against oxidative stress but have little or no effect on life span in Caenorhabditis elegans

Doonan, R., McElwee, J. J., Matthijssens, F., Walker, G. A., Houthoofd, K., Back, P., Matscheski, A., Vanfleteren, J. R., & Gems, D. (2008) · Genes & Development · doi:10.1101/gad.504808 · Cited by 423

Oxidative Stress, Chronic Disease, and Muscle Wasting

Moylan, J. S., & Reid, M. B. (2007) · Muscle & Nerve · doi:10.1002/mus.20743 · Cited by 416

Glutamic and aminoadipic semialdehydes are the main carbonyl products of metal-catalyzed oxidation of proteins

Requena, J. R., Chao, C.-C., Levine, R. L., & Stadtman, E. R. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.98.1.69 · Cited by 415

Selective iron chelation in Friedreich ataxia: biologic and clinical implications

Boddaert, N., Le Quan Sang, K. H., Rötig, A., Leroy-Willig, A., Gallet, S., Brunelle, F., Sidi, D., Thalabard, J.-C., Munnich, A., & Cabantchik, Z. I. (2007) · Blood · doi:10.1182/blood-2006-12-065433 · Cited by 409

The role of antioxidants in photoprotection: A critical review

Chen, L., Hu, J. Y., & Wang, S. Q. (2012) · Journal of the American Academy of Dermatology · doi:10.1016/j.jaad.2012.02.009 · Cited by 402

The Biological Relevance of Direct Antioxidant Effects of Polyphenols for Cardiovascular Health in Humans Is Not Established1–4

Hollman, P. C. H., Cassidy, A., Comte, B., Heinonen, M., Richelle, M., Richling, E., Serafini, M., Scalbert, A., Sies, H., & Vidry, S. (2011) · The Journal of Nutrition · doi:10.3945/jn.110.131490 · Cited by 406

Antioxidants: Molecules, medicines, and myths

Gutteridge, J. M. C., & Halliwell, B. (2010) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2010.02.071 · Cited by 405

Faster superoxide dismutase mutants designed by enhancing electrostatic guidance

Getzoff, E. D., Cabelli, D. E., Fisher, C. L., Parge, H. E., Viezzoli, M. S., Banci, L., & Hallewell, R. A. (1992) · Nature · doi:10.1038/358347a0 · Cited by 399

Artifacts in Cell Culture: Rapid Generation of Hydrogen Peroxide on Addition of (−)-Epigallocatechin, (−)-Epigallocatechin Gallate, (+)-Catechin, and Quercetin to Commonly Used Cell Culture Media

Long, L. H., Clement, M. V., & Halliwell, B. (2000) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.2000.2895 · Cited by 390

Chapter 7 Protein Oxidation Processes in Aging Brain

Butterfield, D. A., & Stadtman, E. R. (1997) · Advances in cell aging and gerontology · doi:10.1016/s1566-3124(08)60057-7 · Cited by 390

Antioxidant Therapies for Traumatic Brain Injury

Hall, E. D., Vaishnav, R. A., & Mustafa, A. G. (2010) · Neurotherapeutics · doi:10.1016/j.nurt.2009.10.021 · Cited by 390

Characterization of three isoforms of mammalian peroxiredoxin that reduce peroxides in the presence of thioredoxin

Chae, H. Z., Kim, H. J., Kang, S. W., & Rhee, S. G. (1999) · Diabetes Research and Clinical Practice · doi:10.1016/s0168-8227(99)00037-6 · Cited by 390

Null mutation of copper/zinc superoxide dismutase in Drosophila confers hypersensitivity to paraquat and reduced longevity.

Phillips, J. P., Campbell, S. D., Michaud, D., Charbonneau, M., & Hilliker, A. J. (1989) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.86.8.2761 · Cited by 389

Antioxidant properties of phenols

Foti, M. C. (2007) · Journal of Pharmacy and Pharmacology · doi:10.1211/jpp.59.12.0010 · Cited by 382

Foliar oxidative stress and insect herbivory: Primary compounds, secondary metabolites, and reactive oxygen species as components of induced resistance

Bi, J. L., & Felton, G. W. (1995) · Journal of Chemical Ecology · doi:10.1007/bf02035149 · Cited by 376

Complexes of Iron with Phenolic Compounds from Soybean Nodules and Other Legume Tissues: Prooxidant and Antioxidant Properties

Moran, J. F., Klucas, R. V., Grayer, R. J., Abian, J., & Becana, M. (1997) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(96)00426-1 · Cited by 369

Mechanisms of disuse muscle atrophy: role of oxidative stress

Powers, S. K., Kavazis, A. N., & DeRuisseau, K. C. (2005) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00469.2004 · Cited by 368

Antioxidant defense mechanisms in murine epidermis and dermis and their responses to ultraviolet light

Shindo, Y., Witt, E., & Packer, L. (1993) · Journal of Investigative Dermatology · doi:10.1111/1523-1747.ep12469048 · Cited by 363

Oxidative stress in anxiety and comorbid disorders

Hovatta, I., Juhila, J., & Donner, J. (2010) · Neuroscience Research · doi:10.1016/j.neures.2010.08.007 · Cited by 365

Towards a unifying, systems biology understanding of large-scale cellular death and destruction caused by poorly liganded iron: Parkinson’s, Huntington’s, Alzheimer’s, prions, bactericides, chemical toxicology and others as examples

Kell, D. B. (2010) · Archives of Toxicology · doi:10.1007/s00204-010-0577-x · Cited by 361

Ferritin as a source of iron for oxidative damage

Reif, D. W. (1992) · Free Radical Biology and Medicine · doi:10.1016/0891-5849(92)90091-t · Cited by 357

Oxidative stress in athletes during extreme endurance exercise

Mastaloudis, A., Leonard, S. W., & Traber, M. G. (2001) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(01)00667-0 · Cited by 352

Oxidative stress and proinflammatory effects of carbon black and titanium dioxide nanoparticles: role of particle surface area and internalized amount

Hussain, S., Boland, S., Baeza-Squiban, A., Hamel, R., Thomassen, L. C. J., Martens, J. A., Billon-Galland, M. A., Fleury-Feith, J., Moisan, F., Pairon, J.-C., et al. (2009) · Toxicology · doi:10.1016/j.tox.2009.04.001 · Cited by 347

On the antioxidant properties of kynurenic acid: free radical scavenging activity and inhibition of oxidative stress

Lugo-Huitrón, R., Blanco-Ayala, T., Ugalde-Muñiz, P., Carrillo-Mora, P., Pedraza-Chaverrí, J., Silva-Adaya, D., Maldonado, P. D., Torres, I., Pinzón, E., Ortiz-Islas, E., et al. (2011) · Neurotoxicology and Teratology · doi:10.1016/j.ntt.2011.07.002 · Cited by 346

The chemistry of nitroxyl (HNO) and implications in biology

Miranda, K. M. (2005) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2004.08.010 · Cited by 339

Molecular mechanisms of iron uptake in fungi

Kosman, D. J. (2003) · Molecular Microbiology · doi:10.1046/j.1365-2958.2003.03368.x · Cited by 331

Changes in free-radical scavenging ability of kombucha tea during fermentation

Jayabalan, R., Subathradevi, P., Marimuthu, S., Sathishkumar, M., & Swaminathan, K. (2008) · Food Chemistry · doi:10.1016/j.foodchem.2007.12.037 · Cited by 328

Skin aging and oxidative stress: Equol’s anti-aging effects via biochemical and molecular mechanisms

Lephart, E. D. (2016) · Ageing Research Reviews · doi:10.1016/j.arr.2016.08.001 · Cited by 325

The antioxidant paradox: less paradoxical now?

Halliwell, B. (2013) · British Journal of Clinical Pharmacology · doi:10.1111/j.1365-2125.2012.04272.x · Cited by 318

Lipid peroxidation in erythrocytes

Clemens, M. R., & Waller, H. D. (1987) · Chemistry and Physics of Lipids · doi:10.1016/0009-3084(87)90068-5 · Cited by 318

Optimization of extraction conditions of antioxidant phenolic compounds from mashua (Tropaeolum tuberosum Ruíz & Pavón) tubers

Chirinos, R., Rogez, H., Campos, D., Pedreschi, R., & Larondelle, Y. (2007) · Separation and Purification Technology · doi:10.1016/j.seppur.2006.12.005 · Cited by 320

Melatonin: Action as antioxidant and potential applications in human disease and aging

Bonnefont-Rousselot, D., & Collin, F. (2010) · Toxicology · doi:10.1016/j.tox.2010.04.008 · Cited by 320

Recent advances in biorefinery of astaxanthin from Haematococcus pluvialis

Khoo, K. S., Lee, S. Y., Ooi, C. W., Fu, X., Miao, X., Ling, T. C., & Show, P. L. (2019) · Bioresource Technology · doi:10.1016/j.biortech.2019.121606 · Cited by 318

Molecular Basis of Electrophilic and Oxidative Defense: Promises and Perils of Nrf2

Ma, Q., & He, X. (2012) · Pharmacological Reviews · doi:10.1124/pr.110.004333 · Cited by 317

Free Radicals and Extrinsic Skin Aging

Poljšak, B., & Dahmane, R. (2012) · Dermatology Research and Practice · doi:10.1155/2012/135206 · Cited by 316

Dextran and polymer polyethylene glycol (PEG) coating reduce both 5 and 30 nm iron oxide nanoparticle cytotoxicity in 2D and 3D cell culture

Yu, M., Huang, S., Yu, K. J., & Clyne, A. M. (2012) · International Journal of Molecular Sciences · doi:10.3390/ijms13055554 · Cited by 308

Role of hippocampal oxidative stress in memory deficits induced by sleep deprivation in mice

Silva, R. H., Abílio, V. C., Takatsu, A. L., Kameda, S. R., Grassl, C., Chehin, A. B., Medrano, W. A., Calzavara, M. B., Registro, S., Andersen, M. L., et al. (2004) · Neuropharmacology · doi:10.1016/j.neuropharm.2003.11.032 · Cited by 307

Antioxidant activity of mycosporine-like amino acids isolated from three red macroalgae and one marine lichen

de la Coba, F., Aguilera, J., Figueroa, F. L., de Gálvez, M. V., & Herrera, E. (2009) · Journal of Applied Phycology · doi:10.1007/s10811-008-9345-1 · Cited by 302

Management of oxidative stress and other pathologies in Alzheimer’s disease

Simunkova, M., Alwasel, S. H., Alhazza, I. M., Jomova, K., Kollar, V., Rusko, M., & Valko, M. (2019) · Archives of Toxicology · doi:10.1007/s00204-019-02538-y · Cited by 303

Effects of polystyrene microbeads in marine planktonic crustaceans

Gambardella, C., Morgana, S., Ferrando, S., Bramini, M., Piazza, V., Costa, E., Garaventa, F., & Faimali, M. (2017) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2017.07.036 · Cited by 296

Modulation of leukocyte–endothelial interactions by reactive metabolites of oxygen and nitrogen: relevance to ischemic heart disease

Grisham, M. B., Granger, D. N., & Lefer, D. J. (1998) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(98)00094-x · Cited by 293

The Role of Antioxidants in Skin Cancer Prevention and Treatment

Godic, A., Poljšak, B., Adamic, M., & Dahmane, R. (2014) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2014/860479 · Cited by 293

Activation of the hypothalamic-pituitary-adrenal stress axis induces cellular oxidative stress

Spiers, J. G., Chen, H.-J. C., Sernia, C., & Lavidis, N. A. (2015) · Frontiers in Neuroscience · doi:10.3389/fnins.2014.00456 · Cited by 292

Glutathione peroxidase-catalase cooperativity is required for resistance to hydrogen peroxide by mature rat oligodendrocytes

Baud, O., Greene, A. E., Li, J., Wang, H., Volpe, J. J., & Rosenberg, P. A. (2004) · The Journal of Neuroscience · doi:10.1523/jneurosci.3989-03.2004 · Cited by 292

The biology of ergothioneine, an antioxidant nutraceutical

Borodina, I., Kenny, L. C., McCarthy, C. M., Paramasivan, K., Pretorius, E., Roberts, T. J., van der Hoek, S. A., & Kell, D. B. (2020) · Nutrition Research Reviews · doi:10.1017/s0954422419000301 · Cited by 296

Artemisinin and the antimalarial endoperoxides: from herbal remedy to targeted chemotherapy

Meshnick, S. R., Taylor, T. E., & Kamchonwongpaisan, S. (1996) · Microbiological Reviews · doi:10.1128/mmbr.60.2.301-315.1996 · Cited by 710

The chemical defensome: Environmental sensing and response genes in the Strongylocentrotus purpuratus genome

Goldstone, J. V., Hamdoun, A., Cole, B. J., Howard-Ashby, M., Nebert, D. W., Scally, M., Dean, M., Epel, D., Hahn, M. E., & Stegeman, J. J. (2006) · Developmental Biology · doi:10.1016/j.ydbio.2006.08.066 · Cited by 280

Superoxide Dismutases in Candida albicans : Transcriptional Regulation and Functional Characterization of the Hyphal-induced SOD5 Gene

Martchenko, M., Alarco, A.-M., Harcus, D., & Whiteway, M. (2004) · Molecular Biology of the Cell · doi:10.1091/mbc.e03-03-0179 · Cited by 290

Antioxidants from macroalgae: potential applications in human health and nutrition

Cornish, M. L., & Garbary, D. J. (2010) · ALGAE · doi:10.4490/algae.2010.25.4.155 · Cited by 290

Design of iron chelators with therapeutic application

Liu, Z. D., & Hider, R. C. (2002) · Coordination Chemistry Reviews · doi:10.1016/s0010-8545(02)00050-4 · Cited by 287

Skeletal muscle insulin resistance: role of mitochondria and other ROS sources

Di Meo, S., Iossa, S., & Venditti, P. (2017) · Journal of Endocrinology · doi:10.1530/joe-16-0598 · Cited by 282

On the history of oxidative stress: Concept and some aspects of current development

Sies, H. (2018) · Current Opinion in Toxicology · doi:10.1016/j.cotox.2018.01.002 · Cited by 285

A novel hypothesis of lipofuscinogenesis and cellular aging based on interactions between oxidative stress and autophagocytosis

Brunk, U. T., Jones, C. B., & Sohal, R. S. (1992) · Mutation Research/DNAging · doi:10.1016/0921-8734(92)90042-n · Cited by 274

HO 2 •: The Forgotten Radical

de Grey, A. D. N. J. (2002) · DNA and Cell Biology · doi:10.1089/104454902753759672 · Cited by 279

Effect of exercise therapy on lipid profile and oxidative stress indicators in patients with type 2 diabetes

Gordon, L. A., Morrison, E. Y., McGrowder, D. A., Young, R., Fraser, Y. T. P., Zamora, E. M., Alexander-Lindo, R. L., & Irving, R. R. (2008) · BMC Complementary and Alternative Medicine · doi:10.1186/1472-6882-8-21 · Cited by 275

Metabolism of Alcohol

Lieber, C. S. (2005) · Clinics in Liver Disease · doi:10.1016/j.cld.2004.10.005 · Cited by 274

On the selectivity of superoxide dismutase mimetics and its importance in pharmacological studies

Muscoli, C., Cuzzocrea, S., Riley, D. P., Zweier, J. L., Thiemermann, C., Wang, Z., & Salvemini, D. (2003) · British Journal of Pharmacology · doi:10.1038/sj.bjp.0705430 · Cited by 271

Iron Chelation Improves Endothelial Function in Patients With Coronary Artery Disease

Duffy, S. J., Biegelsen, E. S., Holbrook, M., Russell, J. D., Gokce, N., Keaney, J. F., & Vita, J. A. (2001) · Circulation · doi:10.1161/01.cir.103.23.2799 · Cited by 271

Regulation of obesity and insulin resistance by nitric oxide

Sansbury, B. E., & Hill, B. G. (2014) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2014.05.016 · Cited by 274