Airway Management in Trauma
Open accessAbstract
Airway management in the trauma patient presents numerous unique challenges beyond placement of an endotracheal tube and outcomes are dependent on the provider's ability to anticipate difficulty. Airway management strategies for the care of the polytrauma patient are reviewed, with specific considerations for those presenting with traumatic brain injury, suspected c-spine injury, the contaminated airway, the agitated trauma patient, maxillofacial trauma, and the traumatized airway. An approach to airway management that considers the potential anatomic and physiologic challenges in caring for these complicated trauma patients is presented.
AI snapshot
Written from the paper’s full text.
TL;DR
This review outlines a physiology-first approach to trauma airway management, emphasizing resuscitation before intubation and anticipating anatomic and physiologic difficulty. It covers TBI, suspected cervical spine injury, contaminated airway, agitation, maxillofacial trauma, laryngotracheal injury, awake intubation, RSI, preoxygenation, and front-of-neck airway access.
Key findings
- Trauma accounts for 20% to 30% of emergency department intubations; 90% of difficult intubations are unanticipated. Cervical spine injuries occur in approximately 2% of the general trauma population and 6% to 8% of patients with head and facial trauma, while secondary neurologic deterioration is rare at 0.03%.
- Physiologic derangements are common and consequential: postintubation hypotension occurs in 23% to 46% of emergency airway cases, shock index greater than 0.8 identifies particular risk, and combined hypoxemia plus hypotension has an adjusted odds of death double that of either alone. Preintubation oxygen saturation less than 95% risks abrupt desaturation within 90 seconds of apnea.
- Airway contamination decreases first-attempt intubation success regardless of GlideScope or direct laryngoscopy in a retrospective review of more than 4600 intubations. In 1078 trauma patients intubated for discretionary indications, 62% had a significant head injury on investigation.
- Primary airway trauma is uncommon, with reported incidence less than 1% (0.4% blunt, 4.5% penetrating), and front-of-neck airway is rare at 0.05% to 1.7% of ED-based intubations. For RSI, induction agent dose should be reduced by at least 50% in hypotension or shock index greater than 0.8, rocuronium less than 1.0 mg/kg is inadequate with 1.2 to 1.6 mg/kg recommended, and ketamine 1 to 1.5 mg/kg may facilitate cooperation.
Methods
- Narrative clinical review/guidance; no primary study design, dataset, or formal analysis is reported.
- Synthesizes cited literature and expert opinion into scenario-based management pearls and algorithms for TBI, suspected cervical spine injury, contaminated airway, agitated patient, maxillofacial injuries, traumatized airway, awake intubation, RSI, preoxygenation, and FONA.
- Main analysis is qualitative synthesis; no quantitative meta-analysis or statistical testing is reported.
Limitations
- The paper states that prehospital endotracheal intubation data are conflicting, and the Eastern Association for the Surgery of Trauma could reach no conclusion regarding prehospital intubation for traumatic brain injury with or without RSI because of diversity in patient population, airway algorithms, EMS experience, and reporting.
- The paper states limited published evidence that cervical spine collars and immobilization prevent secondary spinal cord injury, inconsistent literature comparing intubation devices in cervical spine immobilization with no consensus on optimal approach, and limited evidence for FONA that will likely remain limited.
- Evident from the text: this is a narrative review without a systematic search or formal quality appraisal, and many recommendations are expert- or physiology-based, with some cited evidence from simulation or cadaveric studies.
Model-written summary. Check it against the paper before relying on it.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
66 of 145 cited sources checked · 20 supported · 4 flagged · accuracy not yet measured
- Premisecitation
Even in patients with known cervical spine injuries, secondary neurologic deterioration is rare, with a reported incidence of 0.03%.
“even in patients with known cervical spine injuries, secondary neurologic deterioration is rare, with a reported incidence of 0.03%.33,[37][38][39]”
Quote in the paperSubstantial claim1 of 4 sources checked- cites [33] Manoach, 2007, Manual in-line stabilization for acute airway management of suspected cervical spine injury: historical review and current questions, Ann Emerg Med source
- cites [37] Durga, 2014, Neurological deterioration during intubation in cervical spine disorders, Indian J Anaesth source
In “Evidence of Cervical Injury Following Intubation” (page not available), the paper says approximately 5% of patients admitted with traumatic cervical injury deteriorate neurologically, not 0.03%. It separately describes published reports of deterioration associated with intubation as few, but gives no 0.03% incidence for patients with known cervical spine injuries. (LLM, conf=0.88)
Checked by a reasoning model — may be wrong.
Experimental — accuracy not yet measured - cites [38] Crosby, 2006, Airway management in adults after cervical spine trauma, Anesthesiology source
- cites [39] Farmer, 1998, Neurologic deterioration after cervical spinal cord injury, J Spinal Disord source
- Premisecitation
Patients with mandibular fractures in 2 or more locations may be easier to intubate due to increased mobility of the mandible and attached soft tissues.
“Although patients with mandibular fractures in 2 or more locations may be easier to intubate due to increased mobility of the mandible and attached soft tissues”
Quote in the paperNot a substantial claim1 of 2 sources checked- cites [64] Bowman-Howard, 2000, Management of the traumatized airway
Not checked in the free run.
- cites [66] Krausz, 2009, Maxillofacial trauma patient: coping with the difficult airway, World J Emerg Surg source
In “Maxillofacial Trauma and Airway Injuries” (page unavailable), the paper says a bilateral anterior mandibular fracture may displace the tongue backward and block the airway. “The Complexity of the situation” describes maxillofacial trauma as often making intubation difficult. The paper does not describe increased mandibular mobility as making these patients easier to intubate. (LLM, conf=0.78)
Checked by a reasoning model — may be wrong.
Experimental — accuracy not yet measured
- Premisecitation
Complications associated with jet ventilation are unacceptably high.
“However, recent reviews have shown that complications associated with jet ventilation are unacceptably high and wire-guided approaches are not as easy or successful as once believed.[114][115][116][117]”
Quote in the paperSubstantial claim3 of 4 sources checked- cites [114] Duggan, 2016, Transtracheal jet ventilation in the “can’t intubate can’t oxygenate” emergency: a systematic review, Br J Anaesth source
- cites [115] Marshall, 2016, Evidence is important: safety considerations for emergency catheter cricothyroidotomy, Acad Emerg Med source
The opening section acknowledges that catheter oxygenation is inherently risky but says refinements have made complication rates significantly lower. “Evidence of Safety and Need for Ongoing Training” reports few complications when the prescribed technique was used. The paper discusses how to mitigate barotrauma, rather than concluding that complications are unacceptably high. (LLM, conf=0.85)
Checked by a reasoning model — may be wrong.
Experimental — accuracy not yet measured - cites [116] Cook, 2011, Major complications of airway management in the UK: results of the Fourth National Audit Project of the Royal College of Anaesthetists and the Difficult Airway Society. Part 1: anaesthesia, Br J Anaesth source
The Emergency surgical airway and Discussion sections report a high failure rate for cannula cricothyroidotomy, but do not identify those attempts as jet ventilation or assess jet-ventilation complications. Searches for “jet ventilation” and “trans-tracheal jet ventilation” found no passage addressing the attributed claim. (LLM, conf=0.70)
Experimental — accuracy not yet measured - cites [117] Langvad, 2013, Emergency cricothyrotomy—a systematic review, Scand J Trauma Resusc Emerg Med source
The Methods (Types of interventions; page unavailable) describe how a transtracheal catheter can be used with a jet ventilator, but do not assess complications from jet ventilation. A search for jet-ventilation complications, barotrauma, and adverse events found no passage in our copy calling their rate unacceptably high. (LLM, conf=0.76)
Experimental — accuracy not yet measured
- Premisecitation
There is very limited published evidence to support the notion that cervical spine collars and immobilization prevent secondary spinal cord injury.
“there is very limited published evidence to support the notion that cervical spine collars and immobilization prevent secondary spinal cord injury.28,29”
Quote in the paperSubstantial claim1 of 2 sources checked - Premisecitation
90% of difficult intubations are unanticipated.
“with 90% of difficult intubations unanticipated”
Quote in the paperSubstantial claim1 of 4 sources checked- cites [18] Yentis, 2002, Predicting difficult intubation–worthwhile exercise or pointless ritual?, Anaesthesia source
- cites [19] Nørskov, 2016, Effects of using the simplified airway risk index vs usual airway assessment on unanticipated difficult tracheal intubation—a cluster randomized trial with 64,273 participants, Br J Anaesth source
- cites [20] Teoh, 2016, Prediction in airway management: what is worthwhile, what is a waste of time and what about the future?, Br J Anaesth source
The article (pp. 3–5) reports that 89–91% of difficult intubations were unanticipated in an analysis that excluded patients initially assigned an alternative intubation method. It then says that exclusion is inappropriate and favors an analysis in which approximately half of difficult intubations were predicted. The unqualified 90% claim omits that condition and the authors’ preferred interpretation. (LLM, conf=0.88)
Experimental — accuracy not yet measured - cites [21] Vannucci, 2016, Bedside predictors of difficult intubation: a systematic review, Minerva Anestesiol
- Premisecitation
Prehospital advanced airway management may increase mortality for trauma patients in some circumstances.
“there is a growing body of evidence that prehospital advanced airway management may increase mortality for trauma patients in some circumstances.8,[12][13][14]”
Quote in the paperSubstantial claim2 of 4 sources checked- cites [8] Eckstein, 2000, Effect of prehospital advanced life support on outcomes of major trauma patients, J Trauma source
- cites [12] Stockinger, 2004, Prehospital endotracheal intubation for trauma does not improve survival over bag-valve-mask ventilation, J Trauma source
- cites [13] Stiell, 2008, The OPALS Major Trauma Study: impact of advanced life-support on survival and morbidity, CMAJ source
- cites [14] Lecky, 2008, Emergency intubation for acutely ill and injured patients, Cochrane Database Syst Rev source
- Premisecitation
The incidence of peri-intubation desaturation, hypocapnea, and hypotension in emergency intubations is relatively high.
“Given the relatively high incidence of peri-intubation desaturation, hypocapnea, and hypotension in emergency intubations”
Quote in the paperSubstantial claim3 of 4 sources checked- cites [23] Spaite, 2017, The effect of combined out-of-hospital hypotension and hypoxia on mortality in major traumatic brain injury, Ann Emerg Med source
The Introduction (Background and Significance; page unavailable) says hypoxia occurs frequently and hypotension is very common during prehospital care of patients with traumatic brain injury. It does not establish their incidence specifically around emergency intubation, and the passages do not address hypocapnea. (LLM, conf=0.86)
Experimental — accuracy not yet measured - cites [24] Bodily, 2015, Incidence and duration of continuously measured oxygen desaturation during emergency department intubation, Ann Emerg Med source
The Main Results report oxygen desaturation in 59 of 166 emergency department rapid sequence intubations (35.5%). The paper does not report incidence rates for peri-intubation hypocapnea or hypotension; its discussion of hemodynamic instability does not establish their incidence. (LLM, conf=0.90)
Experimental — accuracy not yet measured - cites [25] Gebremedhn, 2014, The incidence of oxygen desaturation during rapid sequence induction and intubation, World J Emerg Med source
The Discussion reports a high oxygen-desaturation incidence during rapid sequence induction and intubation (55/153, 35.9%), and the techniques section reports hypotension in 23 patients (15%). The study involved patients undergoing operations under general anesthesia with rapid sequence induction, rather than emergency intubations generally. Our copy does not report an incidence of hypocapnea. (LLM, conf=0.89)
Experimental — accuracy not yet measured - cites [26] Heffner, 2012, Predictors of the complication of postintubation hypotension during emergency airway management, J Crit Care source
- Premisecitation
Early mortality from trauma has essentially remained unchanged despite significant advances in prehospital care, injury prevention, and the development of trauma systems.
“Despite significant advances in prehospital care, injury prevention, and the development of trauma systems, early mortality from trauma has essentially remained unchanged.3”
Quote in the paperNot a substantial claim1 of 1 sources checked- cites [3] Pieters, 2016, Comparison of seven videolaryngoscopes with the Macintosh laryngoscope in manikins by experienced and novice personnel, Anaesthesia source
The available copy contains bibliographic information identifying a study of laryngoscopes in manikins, but no passage addressing early trauma mortality. Searches for the mortality statement and for prehospital care, injury prevention, and trauma systems found no matching passage; the claim cannot be verified from this copy. (LLM, conf=0.75)
Experimental — accuracy not yet measured
- Premisecitation
Anatomic markers are in general poor predictors of difficulty with airway management.
“Anatomic markers are in general poor predictors of difficulty with airway management”
Quote in the paperSubstantial claim1 of 4 sources checked- cites [18] Yentis, 2002, Predicting difficult intubation–worthwhile exercise or pointless ritual?, Anaesthesia source
- cites [19] Nørskov, 2016, Effects of using the simplified airway risk index vs usual airway assessment on unanticipated difficult tracheal intubation—a cluster randomized trial with 64,273 participants, Br J Anaesth source
- cites [20] Teoh, 2016, Prediction in airway management: what is worthwhile, what is a waste of time and what about the future?, Br J Anaesth source
In the main text (page unavailable), the authors report that usual assessment predicted about half of difficult direct-laryngoscopy intubations and that systematically recording seven airway parameters did not improve prediction. This supports limited predictive performance, but the claim generalizes from difficult intubation to airway management overall; the paper also identifies some markers useful for predicting difficulty with other techniques. (LLM, conf=0.84)
Experimental — accuracy not yet measured - cites [21] Vannucci, 2016, Bedside predictors of difficult intubation: a systematic review, Minerva Anestesiol
- Premisecitation
There was no statistically significant difference in first-attempt success between the more commonly used VL devices (GlideScope, C-MAC) and DL.
“there was no statistically significant difference in first-attempt success between the more commonly used VL devices (GlideScope, C-MAC) and DL. 45”
Quote in the paperNot a substantial claim1 of 1 sources checked- cites [45] Suppan, 2016, Alternative intubation techniques vs Macintosh laryngoscopy in patients with cervical spine immobilization: systematic review and meta-analysis of randomized controlled trials, Br J Anaesth source
- Premisecitation
Associated condylar fractures may cause a mechanical obstruction limiting mouth opening, making laryngoscopy and intubation difficult.
“associated condylar fractures may cause a mechanical obstruction limiting mouth opening, making laryngoscopy and intubation difficult.64,66”
Quote in the paperNot a substantial claim1 of 2 sources checked- cites [64] Bowman-Howard, 2000, Management of the traumatized airway
Not checked in the free run.
- cites [66] Krausz, 2009, Maxillofacial trauma patient: coping with the difficult airway, World J Emerg Surg source
In “Approach to the Maxillofacial Trauma Patient’s Airway Management” (page not provided), the paper says temporomandibular joint injury can limit mouth opening and complicate airway management. It does not specifically identify condylar fractures or describe a mechanical obstruction caused by them. (LLM, conf=0.86)
Experimental — accuracy not yet measured
- Premisecitation
In cadaveric studies of unstable c-spine injuries, movement occurring with both direct laryngoscopy (DL) and indirect laryngoscopy do not significantly exceed the physiologic values observed with intact spines.
“In cadaveric studies of unstable c-spine injuries, movement occurring with both direct laryngoscopy (DL) and indirect laryngoscopy do not significantly exceed the physiologic values observed with intact spines.35,36”
Quote in the paperSubstantial claim1 of 2 sources checked- cites [35] Hindman, 2016, Intubation biomechanics: laryngoscope force and cervical spine motion during intubation in cadavers—effect of severe distractive-flexion injury on C3–4 motion, J Neurosurg Spine source
- cites [36] Hindman, 2015, Intubation biomechanics: laryngoscope force and cervical spine motion during intubation in cadavers—cadavers versus patients, the effect of repeated intubations, and the effect of type II odontoid fracture on C1-C2 motion, Anesthesiology source
- Premisecitation
Maxillofacial fractures may present dramatically and affect airway management in one of several ways.
“Maxillofacial fractures may present dramatically and affect airway management in one of several ways.63”
Quote in the paperNot a substantial claim1 of 1 sources checked- cites [63] Hutchison, 1990, ABC of major trauma. Major maxillofacial injuries, BMJ source
- Premisecitation
Having a good view with VL does not mean that easy ETI will follow.
“However, having a good view with VL does not mean that easy ETI will follow.46”
Quote in the paperSubstantial claim1 of 1 sources checked- cites [46] Gu, 2016, A deliberately restricted laryngeal view with the GlideScope® video laryngoscope is associated with faster and easier tracheal intubation when compared with a full glottic view: a randomized clinical trial, Can J Anaesth source
- Premisecitation
Manual inline stabilization (MILS) worsens the view obtained with DL in up to 50% of cases.
“Manual inline stabilization (MILS) worsens the view obtained with DL in up to 50% of cases.40”
Quote in the paperSubstantial claim1 of 1 sources checked- cites [40] Thiboutot, 2009, Effect of manual in-line stabilization of the cervical spine in adults on the rate of difficult orotracheal intubation by direct laryngoscopy: a randomized controlled trial, Can J Anaesth source
The Abstract and Discussion report that MILS worsened laryngeal visualization during direct laryngoscopy. But the Abstract’s 50% figure is the rate of failed intubation within 30 seconds in the MILS group, not the proportion of cases in which the view worsened. (LLM, conf=0.88)
Experimental — accuracy not yet measured
- Premisecitation
C-spine immobilization consistently impairs the glottic view with DL.
“c-spine immobilization consistently impairs the glottic view with DL”
Quote in the paperSubstantial claim2 of 3 sources checked- cites [43] Bathory, 2009, Evaluation of the GlideScope for tracheal intubation in patients with cervical spine immobilisation by a semi-rigid collar, Anaesthesia source
- cites [44] Michailidou, 2015, A comparison of video laryngoscopy to direct laryngoscopy for the emergency intubation of trauma patients, World J Surg source
- cites [45] Suppan, 2016, Alternative intubation techniques vs Macintosh laryngoscopy in patients with cervical spine immobilization: systematic review and meta-analysis of randomized controlled trials, Br J Anaesth source
The paper's background says cervical spine immobilization may disrupt airway alignment and jeopardize glottic visualization during direct laryngoscopy. Its Results (Cormack–Lehane grade; page unavailable) also report poorer glottic views with Macintosh laryngoscopy than with alternative devices in immobilized patients. Neither passage establishes that immobilization consistently impairs the view compared with no immobilization, so “consistently” overstates the evidence. (LLM, conf=0.86)
Experimental — accuracy not yet measured
- Premisecitation
RSI is the most common approach for airway management in trauma.
“RSI is the most common approach for airway management in trauma.75,76”
Quote in the paperNot a substantial claim1 of 2 sources checked- cites [75] Dronen, 1999, Rapid-sequence intubation: a safe but ill-defined procedure, Acad Emerg Med source
The paper’s main section discusses RSI in emergency-department patients and its safety and definition, but does not say it is the most common airway-management approach in trauma. Searches for trauma and comparative frequency found no passage addressing that claim; page numbers were not available in our copy. (LLM, conf=0.70)
Experimental — accuracy not yet measured - cites [76] Mace, 2008, Challenges and advances in intubation: rapid sequence intubation, Emerg Med Clin North Am source
- Premisecitation
Indirect hyperangulated video laryngoscopy (VL) consistently provides an improved glottic view.
“indirect hyperangulated video laryngoscopy (VL) consistently provides an improved glottic view”
Quote in the paperSubstantial claim2 of 3 sources checked- cites [43] Bathory, 2009, Evaluation of the GlideScope for tracheal intubation in patients with cervical spine immobilisation by a semi-rigid collar, Anaesthesia source
The Results and Table 2 (page not available in our copy) show that GlideScope views were better than direct Macintosh views in all 50 patients studied. However, the study tested one device under simulated cervical-spine immobilisation; it does not establish that indirect hyperangulated VL consistently improves glottic views across devices and settings. (LLM, conf=0.86)
Experimental — accuracy not yet measured - cites [44] Michailidou, 2015, A comparison of video laryngoscopy to direct laryngoscopy for the emergency intubation of trauma patients, World J Surg source
- cites [45] Suppan, 2016, Alternative intubation techniques vs Macintosh laryngoscopy in patients with cervical spine immobilization: systematic review and meta-analysis of randomized controlled trials, Br J Anaesth source
The Results (Cormack–Lehane grade; page not provided) report significantly better glottic views than Macintosh laryngoscopy for each of five evaluated devices. The claim omits the study's restriction to adults with cervical spine immobilization and describes the devices collectively as indirect hyperangulated VL, a category the reported result does not establish for all five. (LLM, conf=0.85)
Experimental — accuracy not yet measured
- Premisecitation
A recent meta-analysis by Suppan and colleagues reported more failed intubations for DL compared with several alternative intubating devices in patients with c-spine immobilization.
“A recent meta-analysis by Suppan and colleagues 45 reported more failed intubations for DL compared with several alternative intubating devices in patients with c-spine immobilization.”
Quote in the paperNot a substantial claim1 of 1 sources checked- cites [45] Suppan, 2016, Alternative intubation techniques vs Macintosh laryngoscopy in patients with cervical spine immobilization: systematic review and meta-analysis of randomized controlled trials, Br J Anaesth source
The Results (‘Intubation failure at first attempt’; page not provided) report more first-attempt failures with Macintosh laryngoscopy than with alternative devices pooled. But among the five devices analysed individually, only Airtraq significantly reduced failures; the other four did not show a significant difference. The claim overstates the device-specific finding by implying that several alternatives each had fewer failures. (LLM, conf=0.88)
Experimental — accuracy not yet measured
- Premisecitation
With atelectasis, pulmonary contusion, and other lung pathologies, functional residual capacity is diminished and the resultant shunt physiology renders preoxygenation with high FiO2 less effective in preventing desaturation.
“With atelectasis, pulmonary contusion, and other lung pathologies, the FRC is diminished and the resultant shunt physiology renders preoxygenation with a high FiO 2 less effective in preventing desaturation.[106][107][108]”
Quote in the paperSubstantial claim1 of 3 sources checked- cites [106] Mosier, 2017, Understanding preoxygenation and apneic oxygenation during intubation in the critically ill, Intensive Care Med source
- cites [107] Nimmagadda, 2017, Preoxygenation: physiologic basis, benefits, and potential risks, Anesth Analg source
- cites [108] Sirian, 2009, Physiology of apnoea and the benefits of preoxygenation, Cont Educ Anaesth Crit Care Pain source
The ‘Functional residual capacity’ and ‘Physiological shunt and dead space’ sections say that lung disease can reduce FRC and that patients with both shunting and reduced FRC develop hypoxaemia sooner. The ‘Critical illness’ section reports a smaller benefit from preoxygenation in unstable critically ill patients. The paper does not specifically address atelectasis or pulmonary contusion, or establish that shunt physiology itself makes high-FiO₂ preoxygenation less effective in those conditions. (LLM, conf=0.84)
Experimental — accuracy not yet measured
- Premisecitation
In North America, etomidate has been the most commonly used induction agent used for RSI.
“In North America, etomidate has been the most commonly used induction agent used for RSI.”
Quote in the paperNot a substantial claim1 of 2 sources checked- cites [1] Brown, 2015, NEAR III Investigators. Techniques, success, and adverse events of emergency department adult intubations, Ann Emerg Med source
- cites [100] Upchurch, 2017, Comparison of etomidate and ketamine for induction during rapid sequence intubation of adult trauma patients, Ann Emerg Med source
The Discussion (page unavailable) reports that etomidate was used in more than 90% of emergency-department RSIs recorded by a large multicenter registry, supporting its predominance in that setting. The passage does not establish that it was the most commonly used agent for RSI across all of North America or outside emergency departments. (LLM, conf=0.82)
Experimental — accuracy not yet measured
- Premisecitation
Hypoxemia during emergency department RSI is common, occurring in more than one-third of cases.
“Hypoxemia during emergency department (ED) RSI is common, occurring in more than one-third of cases.24”
Quote in the paperNot a substantial claim1 of 1 sources checked- cites [24] Bodily, 2015, Incidence and duration of continuously measured oxygen desaturation during emergency department intubation, Ann Emerg Med source
- Premisecitation
The combination of hypoxemia and hypotension is additive, with an adjusted odds of death double that of the increased mortality associated with either event alone.
“The combination of hypoxemia and hypotension is additive, with an adjusted odds of death double that of the increased mortality associated with either event alone.23,97,98”
Quote in the paperNot a substantial claim2 of 3 sources checked- cites [23] Spaite, 2017, The effect of combined out-of-hospital hypotension and hypoxia on mortality in major traumatic brain injury, Ann Emerg Med source
- cites [97] Wang, 2014, Association of out-of-hospital advanced airway management with outcomes after traumatic brain injury and hemorrhagic shock in the ROC hypertonic saline trial, Emerg Med J source
The Results report adjusted mortality odds for out-of-hospital airway management in shock and TBI groups, not for hypoxemia and hypotension separately or together. A search of our copy for their combined effect found no comparison showing that the adjusted odds of death double relative to either event alone. Page numbers were not available in the indexed passages. (LLM, conf=0.76)
Experimental — accuracy not yet measured - cites [98] Chou, 2015, Field intubation in civilian patients with hemorrhagic shock is associated with higher mortality, J Trauma Acute Care Surg source
- Premisecitation
The decision to proceed with a front of neck airway is often delayed until critical hypoxemia has occurred.
“Cognitive and team-based preparation is vital, as the decision to proceed with a FONA is often delayed until critical hypoxemia has occurred.111”
Quote in the paperSubstantial claim1 of 1 sources checked- cites [111] Law, 2013, The difficult airway with recommendations for management—Part 1-Intubation encountered in an unconscious/induced patient, Can J Anaesth source
- Premisecitation
Apneic oxygenation is facilitated by the pressure gradient between the oropharynx and the alveoli created by the differential uptake of oxygen and delivery of CO2 to and from the alveoli, resulting in the passive transfer of oxygen.
“AO is facilitated by the pressure gradient between the oropharynx and the alveoli created by the differential uptake of oxygen and delivery of CO2 to and from the alveoli, resulting in the passive transfer of oxygen.104,107”
Quote in the paperSubstantial claim1 of 2 sources checked - Premisecitation
The most important determinant of time to desaturation remains preoxygenation status.
“Although recent literature has focused on extending safe apnea time with passive high-flow nasal oxygenation (HFNO) with or without noninvasive ventilation, the most important determinant of time to desaturation remains preoxygenation status.104”
Quote in the paperSubstantial claim1 of 1 sources checked- cites [104] Wong, 2017, The effectiveness of apneic oxygenation during tracheal intubation in various clinical settings: a narrative review, Can J Anaesth source
The practical guide in “Limitations of this review” recommends preoxygenation before intubation and checking that end-tidal oxygen reaches 85–90%. The review also reports that apneic oxygenation can prolong time to desaturation, but it does not establish that preoxygenation status is the most important determinant of that time. Page numbers are unavailable in our copy. (LLM, conf=0.76)
Experimental — accuracy not yet measured
- Premisecitation
With a favorable hemodynamic profile and strong analgesic effect, ketamine is quickly becoming the preferred induction agent for trauma patients.
“With a favorable hemodynamic profile and strong analgesic effect, ketamine is quickly becoming the preferred induction agent for trauma patients.100”
Quote in the paperNot a substantial claim1 of 1 sources checked- cites [100] Upchurch, 2017, Comparison of etomidate and ketamine for induction during rapid sequence intubation of adult trauma patients, Ann Emerg Med source
The Introduction (Background and Importance; page unavailable) describes ketamine’s favorable hemodynamic effects and its emergence as an alternative for trauma intubation. It does not discuss a strong analgesic effect or establish that ketamine is becoming the preferred agent generally; the Background says it remains unclear which agent should be preferred, and the Discussion reports no improvement in patient-centered outcomes over etomidate. (LLM, conf=0.88)
Experimental — accuracy not yet measured
- Premisecitation
Patients with a shock index greater than 0.8 are at particular risk of developing significant hypotension in the postintubation period.
“Patients with a shock index (defined as heart rate divided by SBP) of greater than 0.8 are at particular risk of developing significant hypotension in the postintubation period.82,95,96”
Quote in the paperSubstantial claim1 of 3 sources checked- cites [82] Heffner, 2013, Incidence and factors associated with cardiac arrest complicating emergency airway management, Resuscitation source
- cites [95] Trivedi, 2015, Evaluation of preintubation shock index and modified shock index as predictors of postintubation hypotension and other short-term outcomes, J Crit Care source
- cites [96] Lai, 2016, Systolic blood pressure lower than heart rate upon arrival at and departure from the Emergency Department indicates a poor outcome for adult trauma patients, Int J Environ Res Public Health source
The Background says shock index is a strong predictor of postintubation hemodynamic instability in the emergency department. It does not give a >0.8 threshold or specify significant postintubation hypotension; the threshold it discusses is ≥1 for an uncompensated shock state. The Conclusions concern poor outcomes in adult trauma patients with a reverse shock index <1, not postintubation hypotension. (LLM, conf=0.85)
Experimental — accuracy not yet measured
- Premisecitation
Owing to the association between using etomidate and adrenal suppression, many institutions have moved to alternative induction agents.
“Owing to the association between using etomidate and adrenal suppression, many institutions have moved to alternative induction agents.1,100”
Quote in the paperNot a substantial claim1 of 2 sources checked- cites [1] Brown, 2015, NEAR III Investigators. Techniques, success, and adverse events of emergency department adult intubations, Ann Emerg Med source
- cites [100] Upchurch, 2017, Comparison of etomidate and ketamine for induction during rapid sequence intubation of adult trauma patients, Ann Emerg Med source
The Introduction (Importance) states that etomidate causes transient adrenal suppression. The Introduction (Goals of This Investigation) says the authors’ institution switched from etomidate to ketamine because of concerns about adrenal dysfunction, but the paper does not establish that many institutions made that switch. (LLM, conf=0.88)
Experimental — accuracy not yet measured
- Premisecitation
Apneic oxygenation using conventional or specialized nasal prongs to administer high-flow oxygen (10-70 LPM) may extend the safe apnea time after an RSI by continuously replenishing the FRC oxygen stores.
“By continuously replenishing the FRC oxygen stores, apneic oxygenation using conventional or specialized nasal prongs to administer high-flow oxygen (10-70 LPM) may extend the safe apnea time after an RSI.103,104”
Quote in the paperSubstantial claim1 of 2 sources checked - Premisecitation
Even transient drops in blood pressure are associated with adverse outcomes in trauma patients.
“even transient drops in blood pressure are associated with adverse outcomes in trauma patients.23,[92][93][94]”
Quote in the paperSubstantial claim2 of 4 sources checked- cites [23] Spaite, 2017, The effect of combined out-of-hospital hypotension and hypoxia on mortality in major traumatic brain injury, Ann Emerg Med source
The Introduction (Background and Significance) says that a single episode of hypotension doubles mortality, supporting the point about transient blood-pressure drops. The paper addresses patients with major traumatic brain injury, however, not trauma patients generally; no page number is provided in our copy. (LLM, conf=0.85)
Experimental — accuracy not yet measured - cites [92] Green, 2012, Evaluation of the incidence, risk factors, and impact on patient outcomes of postintubation hemodynamic instability, CJEM source
The Results report higher unadjusted mortality among ED patients with postintubation hypotension, and Table 6 reports deaths among patients with transient hypotension. But the paper does not establish an adverse-outcome association specifically for transient drops in trauma patients; its discussion says the overall mortality association was not present after adjustment and identifies sustained hypotension as associated with increased mortality. (LLM, conf=0.85)
Experimental — accuracy not yet measured - cites [93] Green, 2015, Postintubation hypotension in intensive care unit patients: a multicenter cohort study, J Crit Care source
- cites [94] Heffner, 2012, The frequency and significance of postintubation hypotension during emergency airway management, J Crit Care source
- Premisecitation
A failed oxygenation situation is dynamic and characterized by a rapidly falling oxygen saturation despite maximal efforts to reoxygenate the patient.
“No specific oxygen saturation level should be used as a trigger to perform FONA, recognizing that a failed oxygenation situation is dynamic and characterized by a rapidly falling oxygen saturation despite maximal efforts to reoxygenate the patient.111”
Quote in the paperSubstantial claim1 of 1 sources checked- cites [111] Law, 2013, The difficult airway with recommendations for management—Part 1-Intubation encountered in an unconscious/induced patient, Can J Anaesth source
- Premisecitation
RSI in underresuscitated patients may result in unintended poor outcomes, including critical hypoxemia and circulatory collapse.
“RSI in underresuscitated patients may result in unintended poor outcomes, including critical hypoxemia and circulatory collapse.82,83”
Quote in the paperSubstantial claim1 of 2 sources checked- cites [82] Heffner, 2013, Incidence and factors associated with cardiac arrest complicating emergency airway management, Resuscitation source
- cites [83] Perbet, 2015, Incidence of and risk factors for severe cardiovascular collapse after endotracheal intubation in the ICU: a multicenter observational study, Crit Care source
The Results report desaturation during intubation, and the Discussion addresses severe cardiovascular collapse after intubation. The Discussion also describes possible hypovolemia before induction, but it does not establish that underresuscitation specifically increases the risk of either outcome during rapid sequence intubation. The paper gives no page numbers for these passages. (LLM, conf=0.82)
Experimental — accuracy not yet measured
- Premisecitation
The incidence of post intubation hypotension is high in patients requiring emergency airway management (23%-46%).
“The incidence of post intubation hypotension is high in patients requiring emergency airway management (23%-46%)”
Quote in the paperSubstantial claim2 of 4 sources checked- cites [23] Spaite, 2017, The effect of combined out-of-hospital hypotension and hypoxia on mortality in major traumatic brain injury, Ann Emerg Med source
The Introduction describes hypotension as common early in the care of traumatic brain injury, but gives no post-intubation incidence. The Limitations section says the study did not analyze the timing of low blood-pressure readings or evaluate interventions. Searches for post-intubation hypotension and emergency airway management found no support for the claimed 23%–46% range. (LLM, conf=0.76)
Experimental — accuracy not yet measured - cites [92] Green, 2012, Evaluation of the incidence, risk factors, and impact on patient outcomes of postintubation hemodynamic instability, CJEM source
The Results (Abstract) report postintubation hemodynamic instability in 44% of 218 emergency-department patients, supporting the claim that it is common. The paper does not report a 23%–46% incidence range; its Discussion gives 0%–38.6% for previous studies. (LLM, conf=0.88)
Experimental — accuracy not yet measured - cites [93] Green, 2015, Postintubation hypotension in intensive care unit patients: a multicenter cohort study, J Crit Care source
- cites [94] Heffner, 2012, The frequency and significance of postintubation hypotension during emergency airway management, J Crit Care source
- Premisecitation
A study comparing standard full-dose ketamine with etomidate in trauma patients showed no survival benefit of one agent over the other.
“A study comparing standard full-dose ketamine with etomidate in trauma patients showed no survival benefit of one agent over the other.100”
Quote in the paperSubstantial claim1 of 1 sources checked- cites [100] Upchurch, 2017, Comparison of etomidate and ketamine for induction during rapid sequence intubation of adult trauma patients, Ann Emerg Med source
- Premisecitation
In the hospital setting, delayed intubation is associated with increased mortality in noncritically injured trauma patients.
“In the hospital setting, delayed intubation is associated with increased mortality in noncritically injured trauma patients.11”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [11] Miraflor, 2011, Timing is everything: delayed intubation is associated with increased mortality in initially stable trauma patients, J Surg Res source
- Premisecitation
No conclusion could be reached regarding prehospital intubation for patients with traumatic brain injury, with or without rapid sequence intubation.
“No conclusion could be reached regarding prehospital intubation for patients with traumatic brain injury, with or without RSI [rapid sequence intubation].”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [15] Mayglothling, 2012, Emergency tracheal intubation immediately following traumatic injury: an Eastern Association for the Surgery of Trauma practice management guideline, J Trauma Acute Care Surg source
- Premisecitation
When performed by skilled emergency medical services (EMS) providers, advanced airway management is associated with a significant decrease in mortality.
“More recent data suggest that when performed by skilled emergency medical services (EMS) providers, advanced airway management is associated with a significant decrease in mortality.9,10”
Quote in the paperSubstantial claim0 of 2 sources checked - Premisecitation
Impact brain apnea (IBA) from head trauma results in a primary respiratory arrest without significant parenchymal injury to the brain.
“IBA from head trauma results in a primary respiratory arrest without significant parenchymal injury to the brain.27”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [27] Wilson, 2016, Impact brain apnoea–a forgotten cause of cardiovascular collapse in trauma, Resuscitation source
- Interpretationreasoning
This observation in part explains the comparatively poor survival rates for trauma patients who are intubated in the prehospital setting.
“This observation in part explains the comparatively poor survival rates for trauma patients who are intubated in the prehospital setting.”
Quote in the paperSubstantial claim - Premisecitation
Advanced airway management can be performed in the prehospital setting without delaying transfer to a trauma center.
“there is evidence to support the argument that advanced airway management can be performed in the prehospital setting without delaying transfer to a trauma center.8,9”
Quote in the paperSubstantial claim0 of 2 sources checked - Premisecitation
In one series, 30% to 40% of patients are assessed as having partial or complete airway obstruction on EMS arrival.
“In one series, 30% to 40% of patients are assessed as having partial or complete airway obstruction on EMS arrival.10”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [10] Lockey, 2014, Advanced airway management is necessary in prehospital trauma patients, Br J Anaesth source
- Premisecitation
Head-injured patients with a decreased level of consciousness frequently receive prehospital advanced airway management.
“Head-injured patients with a decreased level of consciousness frequently receive prehospital advanced airway management.10”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [10] Lockey, 2014, Advanced airway management is necessary in prehospital trauma patients, Br J Anaesth source
- Interpretationreasoning
With appropriate treatment, prognosis for IBA is generally good.
“With appropriate treatment, prognosis is generally good.”
Quote in the paperNot a substantial claim - Premisecitation
The presence of airway contamination with either blood or vomitus has been shown to decrease the rate of first-attempt intubation success, regardless of the device used.
“The presence of airway contamination with either blood or vomitus has been shown to decrease the rate of first-attempt intubation success, regardless of the device used.54”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [54] Sakles, 2017, The impact of a soiled airway on intubation success in the Emergency Department when using the GlideScope or the direct laryngoscope, Acad Emerg Med source
- Premisecitation
Primary airway trauma is relatively uncommon in the civilian urban setting, with a reported incidence of less than 1% (0.4% for blunt and 4.5% for penetrating injuries).
“Primary airway trauma is relatively uncommon in the civilian urban setting, with a reported incidence of less than 1% (0.4% for blunt and 4.5% for penetrating injuries).67”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [67] Kummer, 2007, A review of traumatic airway injuries: potential implications for airway assessment and management, Injury source
- Premisecitation
There was no significant difference in complications associated with acute airway management in patients intubated for discretionary indications, as compared with those intubated for higher acuity reasons.
“there was no significant difference in complications associated with acute airway management in patients intubated for discretionary indications, as compared with those intubated for higher acuity reasons.59”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [59] Sise, 2009, Early intubation in the management of trauma patients: indications and outcomes in 1,000 consecutive patients, J Trauma Inj Infect Crit Care source
- Interpretationnone given
The combination of altered levels of consciousness, diminished protective airway reflexes, delayed gastric emptying, and full stomachs place trauma patients at high risk of vomiting and aspiration during airway management.
“The combination of altered levels of consciousness, diminished protective airway reflexes, delayed gastric emptying, and full stomachs place trauma patients at high risk of vomiting and aspiration during airway management.”
Quote in the paperNot a substantial claim - Premisecitation
Concerns that ketamine may raise intracranial pressure and worsen outcomes in TBI is not supported by evidence.
“Concerns that ketamine may raise intracranial pressure and worsen outcomes in TBI is not supported by evidence.61,62”
Quote in the paperNot a substantial claim0 of 2 sources checked - Interpretationnone given
Massive subcutaneous emphysema can distort airway anatomy, further complicating management.
“Massive subcutaneous emphysema can distort airway anatomy, further complicating management.”
Quote in the paperNot a substantial claim - Premisecitation
The primary benefit of a rigid cervical collar is to serve as a reminder about the potential existence of an unstable c-spine injury.
“the primary benefit of a rigid cervical collar is to serve as a reminder about the potential existence of an unstable c-spine injury.”
Quote in the paperNot a substantial claim0 of 2 sources checked- cites [33] Manoach, 2007, Manual in-line stabilization for acute airway management of suspected cervical spine injury: historical review and current questions, Ann Emerg Med source
- cites [53] Aprahamian, 1984, Experimental cervical spine injury model: evaluation of airway management and splinting techniques, Ann Emerg Med source
- Interpretationnone given
If given slowly, a dissociative intravenous dose of 1 to 1.5 mg/kg poses little risk of respiratory depression.
“If given slowly, a dissociative intravenous dose of 1 to 1.5 mg/kg poses little risk of respiratory depression.”
Quote in the paperNot a substantial claim - Premisecitation
Sise and colleagues reviewed 1078 trauma patients intubated for discretionary indications and found that 62% of patients, once investigated, had a significant head injury.
“Sise and colleagues 59 reviewed 1078 trauma patients intubated for discretionary indications (eg, agitation, alcohol intoxication) and found that 62% of patients, once investigated, had a significant head injury.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [59] Sise, 2009, Early intubation in the management of trauma patients: indications and outcomes in 1,000 consecutive patients, J Trauma Inj Infect Crit Care source
- Interpretationreasoning
The chances that movement occurring during controlled airway management will result in cord injury is extremely low.
“the chances that movement occurring during controlled airway management will result in cord injury is extremely low.”
Quote in the paperSubstantial claim - Interpretationreasoning
Blood and vomit in the airway can lead to early and late complications related to difficult airway management and/or aspiration.
“Blood and vomit in the airway can lead to early and late complications related to difficult airway management and/or aspiration.”
Quote in the paperSubstantial claim - Interpretationnone given
PPV in the setting of airway disruption can create or worsen pneumothorax, pneumomediastinum, or subcutaneous emphysema.
“PPV in the setting of airway disruption can create or worsen pneumothorax, pneumomediastinum, or subcutaneous emphysema.”
Quote in the paperSubstantial claim - Interpretationnone given
Patients rendered apneic as part of an RSI without adequate preoxygenation are at high risk of desaturation.
“Patients rendered apneic as part of an RSI without adequate preoxygenation are at high risk of desaturation.”
Quote in the paperNot a substantial claim - Premisecitation
It is unclear whether spinal movement during airway manipulation results in any important differences in clinical outcomes.
“it is unclear whether or not this results in any important differences in clinical outcomes.34”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [34] Kill, 2013, Videolaryngoscopy with glidescope reduces cervical spine movement in patients with unsecured cervical spine, J Emerg Med source
- Interpretationnone given
Dosage recommendations for RSI induction agents are largely based on patients without hemodynamic instability.
“Dosage recommendations for RSI induction agents are largely based on patients without hemodynamic instability.”
Quote in the paperSubstantial claim - Premisecitation
Patients with preintubation oxygen saturations of less than 95% are at risk of abrupt desaturation within 90 seconds of the onset of apnea.
“Patients with preintubation oxygen saturations of less than 95% are at risk of abrupt desaturation within 90 seconds of the onset of apnea.103”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [103] Weingart, 2012, Preoxygenation and prevention of desaturation during emergency airway management, Ann Emerg Med source
- Premisecitation
By the time peripheral oxygen saturation begins to fall, cerebral hypoxemia has already occurred, a phenomenon known as pulse-ox lag.
“By the time peripheral oxygen saturation begins to fall, cerebral hypoxemia has already occurred, a phenomenon known as “pulse-ox lag.” 103”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [103] Weingart, 2012, Preoxygenation and prevention of desaturation during emergency airway management, Ann Emerg Med source
- Premisecitation
Success for high-acuity, low-opportunity events like front of neck airway requires frequent, deliberate practice using simulation.
“Success for high-acuity, low-opportunity events like this requires frequent, deliberate practice using simulation.118”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [118] Petrosoniak, 2013, Beyond crisis resource management, Curr Opin Anaesthesiol source
- Interpretationreasoning
The transition to PPV abruptly increases the intrathoracic pressure, further shifting this gradient.
“The transition to PPV, either through a closed system BVM with an attached with positive end-expiratory pressure (PEEP) valve or with mechanical ventilation once intubated, abruptly increases the intrathoracic pressure, further shifting this gradient.”
Quote in the paperSubstantial claim - Interpretationcitation
The dose of the drug is more important than the choice of drug.
“it is probably true to suggest that the dose of the drug is more important than the choice of drug.”
Quote in the paperSubstantial claim - Interpretationreasoning
In rare situations, front of neck airway may be the first and only invasive airway technique attempted, even in the setting of normal oxygen saturation, for example in massive facial trauma disrupting all recognizable airway landmarks.
“In rare situations, FONA may be the first and only invasive airway technique attempted, even in the setting of normal oxygen saturation; for example, massive facial trauma disrupting all recognizable airway landmarks.”
Quote in the paperNot a substantial claim - Interpretationnone given
All commonly used induction agents will cause hypotension, particularly when a full dose is administered to a volume-constricted patient.
“All commonly used induction agents will cause hypotension, particularly when a full dose is administered to a volume-constricted patient.”
Quote in the paperSubstantial claim - Premisecitation
Delivery of close to 100% oxygen for approximately 4 minutes is required to denitrogenate normal lungs.
“Delivery of close to 100% oxygen for approximately 4 minutes is required to denitrogenate normal lungs and may be most easily accomplished with high-flow, “flush-rate” (40 LPM) oxygen using a conventional non-rebreather mask.105”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [105] Driver, 2017, Flush rate oxygen for emergency airway preoxygenation, Ann Emerg Med source
- Classified as probably not a substantial claim. 39
- May combine two claims. 35
- The quote only partly states this claim. 1
Classified as probably not a substantial claim. May combine two claims.
PremisecitationAdministering too small a dose (<1.0 mg/kg) of rocuronium, particularly in low-flow states, will result in inadequate intubating conditions and a larger dose is recommended (1.2-1.6 mg/kg).
“administering too small a dose (<1.0 mg/kg) of rocuronium, particularly in low-flow states, will result in inadequate intubating conditions and a larger dose is recommended (1.2-1.6 mg/kg).101,102”
Quote in the paperSubstantial claim2 of 2 sources checked- cites [101] Tran, 2015, Rocuronium versus succinylcholine for rapid sequence induction intubation, Cochrane Database Syst Rev source
The Subgroup analysis reports fewer excellent conditions with 0.6–0.7 mg/kg rocuronium than with succinylcholine, but it does not establish that every dose below 1.0 mg/kg produces inadequate conditions. It finds no conclusive evidence that increasing rocuronium doses improves conditions, and the Authors’ conclusions recommend 1 mg/kg when rocuronium is needed—not 1.2–1.6 mg/kg. The cited passages do not address low-flow states. (LLM, conf=0.88)
Checked by a reasoning model — may be wrong.
Experimental — accuracy not yet measured - cites [102] Welch, 2016, Update: does rocuronium create better intubating conditions than succinylcholine for rapid sequence intubation?, Ann Emerg Med source
The Commentary (page not provided) says rocuronium dose may affect intubating conditions and reports that succinylcholine produced better conditions at rocuronium doses of 0.6–0.7 mg/kg. It does not say that every dose below 1.0 mg/kg causes inadequate conditions: it found no difference at 0.9–1.0 mg/kg. It does not address low-flow states or recommend 1.2–1.6 mg/kg. (LLM, conf=0.88)
Experimental — accuracy not yet measured
Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
PremisecitationApplication of MILS results in the need for an increased applied force during laryngoscopy, which paradoxically may lead to more movement during intubation than occurs without MILS.
“Another theoretic concern is that application of MILS results in the need for an increased applied force during laryngoscopy, which paradoxically may lead to more movement during intubation than occurs without MILS.40,41”
Quote in the paperNot a substantial claim1 of 2 sources checked- cites [40] Thiboutot, 2009, Effect of manual in-line stabilization of the cervical spine in adults on the rate of difficult orotracheal intubation by direct laryngoscopy: a randomized controlled trial, Can J Anaesth source
- cites [41] LeGrand, 2007, Craniocervical motion during direct laryngoscopy and orotracheal intubation with the Macintosh and Miller blades: an in vivo cinefluoroscopic study, Anesthesiology source
Probably not a substantial claim: may not pass S3 (load-bearing).
PremisecitationThe incidence of c-spine injuries is approximately 2% in the general trauma population.
“the incidence of c-spine injuries is relatively low (occurring in approximately 2% in the general trauma population”
Quote in the paperNot a substantial claim1 of 4 sources checked- cites [30] Mulligan, 2010, A nationwide review of the associations among cervical spine injuries, head injuries, and facial fractures, J Trauma source
- cites [31] Dupanovic, 2010, Management of the airway in multitrauma, Curr Opin Anaesthesiol source
- cites [32] Thompson, 2009, Association of injury mechanism with the risk of cervical spine fractures, CJEM source
The Characteristics of study subjects section reports that 320 of 17,208 patients (2%) had a clinically important cervical spine injury. The Abstract specifies that these were patients presenting to nine tertiary-care emergency departments after acute blunt trauma to the head or neck, not the general trauma population. The 2% figure is supported, but the claimed population is broader than the study's. (LLM, conf=0.88)
Experimental — accuracy not yet measured - cites [33] Manoach, 2007, Manual in-line stabilization for acute airway management of suspected cervical spine injury: historical review and current questions, Ann Emerg Med source
Probably not a substantial claim: may not pass S3 (load-bearing).
PremisecitationThe incidence of c-spine injuries is 6%-8% in patients with head and facial trauma.
“and 6%-8% in patients with head and facial trauma)”
Quote in the paperNot a substantial claim1 of 4 sources checked- cites [30] Mulligan, 2010, A nationwide review of the associations among cervical spine injuries, head injuries, and facial fractures, J Trauma source
- cites [31] Dupanovic, 2010, Management of the airway in multitrauma, Curr Opin Anaesthesiol source
- cites [32] Thompson, 2009, Association of injury mechanism with the risk of cervical spine fractures, CJEM source
The Characteristics of study subjects section reports cervical spine injury in 320 of 17,208 patients (2%) enrolled after blunt head or neck trauma. Our copy does not report an incidence for patients with head and facial trauma, so it cannot verify the claimed 6%–8% for that group. (LLM, conf=0.72)
Experimental — accuracy not yet measured - cites [33] Manoach, 2007, Manual in-line stabilization for acute airway management of suspected cervical spine injury: historical review and current questions, Ann Emerg Med source
May combine two claims.
PremisecitationThe Ducanto suction-assisted laryngoscopy airway decontamination (SALAD) approach has gained acceptance as a method to manage the soiled airway, although not studied in a clinical setting.
“Although not studied in a clinical setting, the Ducanto suction-assisted laryngoscopy airway decontamination (SALAD) approach has gained acceptance as a method to manage the soiled airway.57,58”
Quote in the paperNot a substantial claim1 of 2 sources checked- cites [57] DuCanto, 2017, Novel airway training tool that simulates vomiting: suction-assisted laryngoscopy assisted decontamination (SALAD) system, West J Emerg Med source
The Introduction describes SALAD as a simulation-based suction approach for managing vomit or blood in the airway, and the Discussion says the study did not evaluate real-world clinical outcomes. The Results report favorable ratings from 40 learners, but do not establish that the approach had gained acceptance as a clinical method for managing soiled airways. Page numbers were not available in our copy. (LLM, conf=0.85)
Experimental — accuracy not yet measured - cites [58] Brainard, 2015, The art of SUCTIONING, JEMS
May combine two claims.
PremisecitationPosterior displacement from fractured maxillofacial segments may cause soft tissue collapse and occlude the airway, which may be worsened by the presence of c-spine collar.
“Posterior displacement from fractured maxillofacial segments may cause soft tissue collapse and occlude the airway, which may be worsened by the presence of c-spine collar.64,65”
Quote in the paperNot a substantial claim1 of 2 sources checked- cites [64] Bowman-Howard, 2000, Management of the traumatized airway
Not checked in the free run.
- cites [65] Jose, 2016, Management of maxillofacial trauma in emergency: an update of challenges and controversies, J Emerg Trauma Shock source
May combine two claims.
PremisecitationSuccess with awake intubation is dependent on meticulous airway topicalization, and in general requires an awake and cooperative patient.
“Success with awake intubation is dependent on meticulous airway topicalization, and in general requires an awake and cooperative patient.72,73”
Quote in the paperSubstantial claim1 of 2 sources checked- cites [72] Higgs, 2016, Airway management in the critically ill: the same, but different, Br J Anaesth source
- cites [73] Lapinsky, 2015, Endotracheal intubation in the ICU, Crit Care source
The paper’s Abstract says some agitated patients cannot undergo awake intubation and describes using topical anesthetic or a local anesthetic spray in an awake, breathing patient. It does not say success depends on meticulous topicalization or generally requires a fully awake and cooperative patient; it explicitly describes successful awake intubation in ICU patients whose consciousness may be reduced by illness. (LLM, conf=0.85)
Experimental — accuracy not yet measured
May combine two claims.
PremisecitationMost of the literature comparing DL with VL in the bloody or vomitus-filled airway is simulation-based, and concern exists about the vulnerability of VL camera lens in the contaminated airway.
“Most of the literature comparing DL with VL in the bloody or vomitus-filled airway is simulation-based, and concern exists about the vulnerability of VL camera lens in the contaminated airway.55,56”
Quote in the paperSubstantial claim1 of 2 sources checked- cites [55] Ohchi, 2016, Evaluation of gum-elastic bougie combined with direct and indirect laryngoscopes in vomitus setting: a randomized simulation trial, Am J Emerg Med source
- cites [56] Mihara, 2015, Comparison of direct and indirect laryngoscopes in vomitus and hematemesis settings: a randomized simulation trial, Biomed Res Int source
The Methods describe a manikin simulation using simulated vomitus and blood, and the Discussion reports that the AWS video monitor was severely disturbed by both contaminants. The Conclusion calls for trials in actual patients. These passages support the simulation example and the concern about a contaminated video view, but do not establish that most of the literature is simulation-based or specifically identify the camera lens as the vulnerable component. Page numbers are unavailable in our copy. (LLM, conf=0.87)
Experimental — accuracy not yet measured
May combine two claims.
PremisecitationLiterature comparing intubation devices in c-spine immobilized patients has yielded inconsistent findings, and no consensus as to the optimal approach.
“Literature comparing intubation devices in c-spine immobilized patients has yielded inconsistent findings, and no consensus as to the optimal approach.38,44,45,48,49”
Quote in the paperSubstantial claim2 of 5 sources checked- cites [38] Crosby, 2006, Airway management in adults after cervical spine trauma, Anesthesiology source
- cites [44] Michailidou, 2015, A comparison of video laryngoscopy to direct laryngoscopy for the emergency intubation of trauma patients, World J Surg source
- cites [45] Suppan, 2016, Alternative intubation techniques vs Macintosh laryngoscopy in patients with cervical spine immobilization: systematic review and meta-analysis of randomized controlled trials, Br J Anaesth source
- cites [48] Kleine-Brueggeney, 2016, Evaluation of six videolaryngoscopes in 720 patients with a simulated difficult airway: a multicentre randomized controlled trial, Br J Anaesth source
The Discussion (page unavailable) says the optimal videolaryngoscope may differ with the circumstances of the difficult airway, supporting the absence of one universally optimal device. But it also says prior studies agree that videolaryngoscopes have higher success rates than the Macintosh laryngoscope, so it does not support a blanket characterization of the findings as inconsistent. This trial used simulated cervical-spine immobilization with reduced mouth opening, rather than studying all immobilized patients. (LLM, conf=0.84)
Experimental — accuracy not yet measured - cites [49] Norris, 2016, Limitations of videolaryngoscopy, Br J Anaesth source
May combine two claims.
PremisecitationThe use of sedation is not routine, and has been associated with increased awake intubation failures.
“The use of sedation is not routine, and has been associated with increased awake intubation failures.74”
Quote in the paperSubstantial claim1 of 1 sources checked- cites [74] Cook, 2011, Major complications of airway management in the UK: results of the Fourth National Audit Project of the Royal College of Anaesthetists and the Difficult Airway Society. Part 2: intensive care and emergency departments, Br J Anaesth source
The Primary airway problem and What do we learn from these observations? sections discuss failed intubation in ICU and emergency departments, but do not identify awake intubation failures or link them to sedation. Searches for awake intubation and sedation found references to sedation holds and tube displacement, not evidence that sedation is non-routine or associated with increased awake intubation failures. Page numbers were unavailable in our copy. (LLM, conf=0.76)
Experimental — accuracy not yet measured
Classified as probably not a substantial claim.
PremisecitationThe 2015 Difficult Airway Society guidelines recommend that the scalpel-bougie technique is the technique of choice for front of neck airway.
“and that the scalpel-bougie technique is the technique of choice.89”
Quote in the paperSubstantial claim1 of 1 sources checked- cites [89] Frerk, 2015, Difficult Airway Society 2015 guidelines for management of unanticipated difficult intubation in adults, Br J Anaesth source
Probably not a substantial claim: may not pass S3 (load-bearing).
PremisecitationNumerous preparatory airway acronyms and checklists have been proposed to reduce errors and adverse events associated with RSI.
“Numerous preparatory airway acronyms and checklists have been proposed to reduce errors and adverse events associated with RSI.85,86”
Quote in the paperNot a substantial claim2 of 2 sources checked- cites [85] Hardy, 2016, BET 2: should real resuscitationists use airway checklists?, Emerg Med J source
The Comments section (page not specified) says airway checklists are increasingly adopted in initiatives designed to reduce adverse events and discusses their use to reduce errors. The paper does not describe preparatory airway acronyms, so it supports the checklist portion but not the full claim. (LLM, conf=0.85)
Experimental — accuracy not yet measured - cites [86] Brindley, 2017, Airway management outside the operating room: how to better prepare, Can J Anaesth source
The Background (page not provided) proposes a mnemonic-based checklist for airway interventions outside the operating room, and the Conclusion says the authors believe it is likely to improve performance. The paper does not establish that numerous such tools have been proposed specifically for RSI or that they reduce errors and adverse events; it notes that supporting data for its checklist may be lacking. (LLM, conf=0.85)
Experimental — accuracy not yet measured
Probably not a substantial claim: may not pass S3 (load-bearing).
PremisecitationFront of neck airway is rare, occurring in 0.05%-1.7% of ED-based intubations.
“Although rare (0.05%-1.7% of ED-based intubations)”
Quote in the paperNot a substantial claim1 of 1 sources checked- cites [111] Law, 2013, The difficult airway with recommendations for management—Part 1-Intubation encountered in an unconscious/induced patient, Can J Anaesth source
May combine two claims.
PremisecitationBoth succinylcholine and rocuronium may be safely used and can provide good intubating conditions.
“both succinylcholine and rocuronium may be safely used and can provide good intubating conditions.101”
Quote in the paperSubstantial claim1 of 1 sources checked- cites [101] Tran, 2015, Rocuronium versus succinylcholine for rapid sequence induction intubation, Cochrane Database Syst Rev source
The Authors’ Conclusions say succinylcholine reliably creates excellent intubating conditions and rocuronium 1 mg/kg can create acceptable conditions as a second-line option. But the Overall completeness and applicability of evidence section explicitly says the review cannot draw conclusions about safety, so it does not support the claim that both may be safely used. (LLM, conf=0.92)
Experimental — accuracy not yet measured
May combine two claims.
PremisecitationThe balance of evidence suggests that high-flow nasal oxygenation as an adjunct to preoxygenation for RSI is both safe and effective.
“Numerous studies have evaluated to effectiveness of HFNO as an adjunct to preoxygenation for RSI, and the balance of evidence suggest the procedure as both safe and effective.104”
Quote in the paperSubstantial claim1 of 1 sources checked- cites [104] Wong, 2017, The effectiveness of apneic oxygenation during tracheal intubation in various clinical settings: a narrative review, Can J Anaesth source
The section on apneic oxygenation in clinical settings reports reduced desaturation in some intubation studies, including one using high-flow nasal oxygen and one involving rapid sequence intubation. But the Conclusion (page unavailable) says most studies were too small to assess serious adverse events and warns that prolonged apneic oxygenation may be risky. The review therefore supports possible effectiveness, not the unqualified claim that HFNO is both safe and effective as an adjunct for RSI. (LLM, conf=0.89)
Experimental — accuracy not yet measured
May combine two claims.
PremisecitationWire-guided approaches are not as easy or successful as once believed.
“However, recent reviews have shown that complications associated with jet ventilation are unacceptably high and wire-guided approaches are not as easy or successful as once believed.[114][115][116][117]”
Quote in the paperSubstantial claim3 of 4 sources checked- cites [114] Duggan, 2016, Transtracheal jet ventilation in the “can’t intubate can’t oxygenate” emergency: a systematic review, Br J Anaesth source
- cites [115] Marshall, 2016, Evidence is important: safety considerations for emergency catheter cricothyroidotomy, Acad Emerg Med source
The Type and Size of Catheter section reports failures with narrow-gauge catheter puncture, but does not identify those attempts as wire-guided. Searches for wire-guided, guidewire, and Seldinger approaches found no passage assessing their ease or success. The copy therefore does not establish the attributed claim. (LLM, conf=0.76)
Experimental — accuracy not yet measured - cites [116] Cook, 2011, Major complications of airway management in the UK: results of the Fourth National Audit Project of the Royal College of Anaesthetists and the Difficult Airway Society. Part 1: anaesthesia, Br J Anaesth source
The Emergency surgical airway section (page unavailable) reports that 12 of 19 narrow-bore and 3 of 7 wide-bore cannula cricothyroidotomy attempts failed. The Discussion (page unavailable) calls the high failure rate concerning, but the paper does not identify those attempts as wire-guided or assess whether wire-guided approaches were once thought easier or more successful. (LLM, conf=0.78)
Experimental — accuracy not yet measured - cites [117] Langvad, 2013, Emergency cricothyrotomy—a systematic review, Scand J Trauma Resusc Emerg Med source
The Discussion reports that surgical techniques were generally faster than Seldinger-based wire-guided kits, which supports the claim that wire-guided approaches may be less easy than assumed. But it also says both approaches had high success rates and found no statistically significant difference between them; it does not support the claim that wire-guided approaches were less successful than once believed. (LLM, conf=0.86)
Experimental — accuracy not yet measured
Probably not a substantial claim: may not pass S3 (load-bearing).
PremisecitationIn the emergency department, 20% to 30% of intubations are for trauma.
“in the emergency department, 20% to 30% intubations are for trauma.1,2”
Quote in the paperNot a substantial claim0 of 2 sources checked- cites [1] Brown, 2015, NEAR III Investigators. Techniques, success, and adverse events of emergency department adult intubations, Ann Emerg Med source
- cites [2] Kerslake, 2015, Tracheal intubation in an urban emergency department in Scotland: a prospective, observational study of 3738 intubations, Resuscitation source
May combine two claims.
InterpretationreasoningPatients with IBA do not respond to simple airway opening maneuvers alone, and may require brief ventilation support to prevent secondary hypoxic insult.
“In contrast to patients with head injury with functional airway obstruction, patients with IBA do not respond to simple airway opening maneuvers alone, and may require brief ventilation support to prevent secondary hypoxic insult.”
Quote in the paperSubstantial claimMay combine two claims.
InterpretationreasoningA proportion of head-injured patients with airway obstruction will respond to basic maneuvers, and those who do not usually have more severe, less survivable injuries.
“A proportion of these patients will respond to basic maneuvers, and those who do not usually have more severe, less survivable injuries.”
Quote in the paperSubstantial claimClassified as probably not a substantial claim.
PremisecitationFor patients with known or suspected airway injury, the safest way to facilitate ETI is placement of the ETT under direct visualization, ideally from the oropharynx to the carina using an FIE.
“For patients with known or suspected airway injury, the safest way to facilitate ETI is placement of the ETT under direct visualization, ideally from the oropharynx to the carina using an FIE.68,70”
Quote in the paperSubstantial claim0 of 2 sources checkedProbably not a substantial claim: may not pass S4 (based). May combine two claims.
Interpretationnone givenVentilatory pressures of 20 cm H2O or more are likely to ventilate the stomach, increasing the risk of regurgitation and aspiration.
“ventilatory pressures of 20 cm H2O or more are likely to ventilate the stomach, increasing the risk of regurgitation and aspiration.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
PremisecitationThe EAST guidelines recommend that aggressive behavior refractory to initial pharmacologic intervention is a discretionary indication for intubation.
“The EAST guidelines recommend that aggressive behavior refractory to initial pharmacologic intervention is a discretionary indication for intubation”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [15] Mayglothling, 2012, Emergency tracheal intubation immediately following traumatic injury: an Eastern Association for the Surgery of Trauma practice management guideline, J Trauma Acute Care Surg source
Probably not a substantial claim: may not pass S3 (load-bearing), S4 (based). May combine two claims.
Interpretationnone givenAgitation can be multifactorial and may be the result of head injury, hypoperfusion, hypoxemia, or intoxication.
“Agitation can be multifactorial and may be the result of head injury, hypoperfusion, hypoxemia, or intoxication.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S4 (based). May combine two claims.
InterpretationreasoningDistortion of facial structures may make obtaining a seal with a BVM device difficult and patients may poorly tolerate PPV, as disruption of tissues may result in worsening bleeding and in cases of associated lower airway trauma, significant subcutaneous emphysema.
“Distortion of facial structures may make obtaining a seal with a BVM device difficult and patients may poorly tolerate PPV, as disruption of tissues may result in worsening bleeding and in cases of associated lower airway trauma, significant subcutaneous emphysema.”
Quote in the paperNot a substantial claimMay combine two claims.
Interpretationnone givenClinical findings suggestive of significant laryngotracheal airway injury include dysphagia, hoarseness, stridor, bleeding in the upper airway, subcutaneous emphysema, expanding hematoma, or in open penetrating injuries, obvious disruption of the larynx or trachea.
“Clinical findings suggestive of significant laryngotracheal airway injury include dysphagia, hoarseness, stridor, bleeding in the upper airway, subcutaneous emphysema, expanding hematoma, or in open penetrating injuries, obvious disruption of the larynx or trachea.”
Quote in the paperSubstantial claimMay combine two claims.
PremisecitationPractitioners have infrequent or limited experience in managing patients with primary airway trauma and existing management guidelines for care of these patients are mostly based on expert opinion.
“practitioners have infrequent or limited experience in managing these patients and existing management guidelines for care of these patients are mostly based on expert opinion.68”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [68] Mercer, 2016, Systematic review of the anaesthetic management of non-iatrogenic acute adult airway trauma, Br J Anaesth source
Probably not a substantial claim: may not pass S4 (based).
Interpretationnone givenAdherence to protocols requiring rigid spinal immobilization and supine positioning may result in catastrophe.
“Adherence to protocols requiring rigid spinal immobilization and supine positioning may result in catastrophe.”
Quote in the paperNot a substantial claimMay combine two claims.
PremisecitationSakles and colleagues retrospectively reviewed more than 4600 intubations and demonstrated that, although airway contamination was associated with a decreased first-attempt success rate, this was irrespective of the choice of GlideScope or DL as the first-attempt device used.
“Recently, Sakles and colleagues 54 retrospectively reviewed more than 4600 intubations and demonstrated that, although airway contamination was associated with a decreased first-attempt success rate, this was irrespective of the choice of GlideScope or DL as the first-attempt device used.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [54] Sakles, 2017, The impact of a soiled airway on intubation success in the Emergency Department when using the GlideScope or the direct laryngoscope, Acad Emerg Med source
Probably not a substantial claim: may not pass S3 (load-bearing), S4 (based). May combine two claims.
Interpretationnone givenAirway management for the patient with a primary injury to the larynx or trachea is a high-stakes scenario, in which the loss of a stable airway can happen rapidly and with little warning.
“Airway management for the patient with a primary injury to the larynx or trachea is a high-stakes scenario, in which the loss of a stable airway can happen rapidly and with little warning.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Premisenone givenHistorically, the application of cricoid pressure (CP) to prevent passive aspiration has been considered an essential component of an RSI.
“Historically, the application of cricoid pressure (CP) to prevent passive aspiration has been considered an essential component of an RSI.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S4 (based).
Interpretationnone givenUncooperative, violent, or agitated patients can encumber adequate assessment, leading to missed injuries and inadequate resuscitation.
“Uncooperative, violent, or agitated patients can encumber adequate assessment, leading to missed injuries and inadequate resuscitation.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
PremisecitationOne option to improve visual navigation past the airway injury is to use a VL-assisted flexible endoscopic intubation.
“One option to improve visual navigation past the airway injury is to use a VL-assisted flexible endoscopic intubation.71”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [71] Sowers, 2016, Use of a flexible intubating scope in combination with a channeled video laryngoscope for managing a difficult airway in the emergency department, J Emerg Med source
Probably not a substantial claim: may not pass S3 (load-bearing), S4 (based).
Interpretationnone givenThe use of any sedative, particularly in the presence of other intoxicating ingestions, may inhibit airway reflexes.
“However, the use of any sedative, particularly in the presence of other intoxicating ingestions, may inhibit airway reflexes.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S4 (based). May combine two claims.
Interpretationnone givenA successful awake intubation is dependent on careful patient selection, and, in particular, identifying anatomic, pathologic, or physiologic features that would make RSI problematic.
“A successful awake intubation is dependent on careful patient selection, and, in particular, identifying anatomic, pathologic, or physiologic features that would make RSI problematic.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S4 (based). May combine two claims.
InterpretationreasoningA difficult airway paradox exists here: patients identified as difficult are selected to undergo a technically more challenging awake approach, a procedure that is performed infrequently by most emergency physicians.
“A difficult airway paradox exists here: patients identified as difficult are selected to undergo a technically more challenging awake approach, a procedure that is performed infrequently by most emergency physicians.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
Interpretationnone givenIn the supine position, the pooling of blood in the oropharynx may stimulate a gag response or vomiting, which in turn may worsen bleeding.
“In the supine position, the pooling of blood in the oropharynx may stimulate a gag response or vomiting, which in turn may worsen bleeding.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing), S4 (based). May combine two claims.
Interpretationnone givenSwelling and tenderness at the temporomandibular joints suggests the presence of condylar factures and the possibility of mechanical trismus.
“swelling and tenderness at the temporomandibular joints suggests the presence of condylar factures and the possibility of mechanical trismus.”
Quote in the paperNot a substantial claimMay combine two claims.
InterpretationreasoningUse of an FIE allows both a diagnostic and therapeutic advantage: visualizing the specific pattern of injury, and facilitating careful ETT placement, while avoiding conversion to a complete transection.
“Use of an FIE allows both a diagnostic and therapeutic advantage: visualizing the specific pattern of injury, and facilitating careful ETT placement, while avoiding conversion to a complete transection.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
Interpretationnone givenMaxillofacial fractures may also cause trismus that may resolve with the neuromuscular blockade; however, differentiating this from a mechanical obstruction before intubation is required and is often difficult.
“Maxillofacial fractures may also cause trismus that may resolve with the neuromuscular blockade; however, differentiating this from a mechanical obstruction before intubation is required and is often difficult.”
Quote in the paperNot a substantial claimClassified as probably not a substantial claim. May combine two claims.
InterpretationreasoningIn the uncommon circumstance in which blood or vomit is overwhelming these management strategies, intubation is not possible and the patient is critically desaturating, rescue oxygenation with a BVM or SGA is unlikely to work and an FONA approach is indicated.
“In the uncommon circumstance in which blood or vomit is overwhelming these management strategies, intubation is not possible and the patient is critically desaturating, rescue oxygenation with a BVM (bag-valvemask) or SGA (supraglottic airway) is unlikely to work and an FONA approach is indicated.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S2 (checkable), S4 (based). May combine two claims.
Interpretationnone givenSafely managing both the anticipated and unanticipated difficult airway requires technical expertise, but decisions of when and how to intervene are equally important determinants of outcome.
“Safely managing both the anticipated and unanticipated difficult airway requires technical expertise; however, decisions of when and how to intervene are equally important determinants of outcome.”
Quote in the paperNot a substantial claimMay combine two claims.
PremisecitationIts routine use remains controversial, with some evidence suggesting it may make various aspects of airway management more challenging.
“However, its routine use remains controversial, with some evidence suggesting it may make various aspects of airway management more challenging.”
Quote in the paperNot a substantial claimMay combine two claims.
InterpretationreasoningInadequate resuscitation of hemorrhagic shock, transition to PPV, loss of sympathetic drive associated with general anesthesia, and the hemodynamic effect of many induction drugs are all contributing factors to postintubation hypotension.
“Inadequate resuscitation of hemorrhagic shock, transition to PPV, loss of sympathetic drive associated with general anesthesia, and the hemodynamic effect of many induction drugs are all contributing factors.”
Quote in the paperSubstantial claimClassified as probably not a substantial claim. The quote only partly states this claim.
InterpretationreasoningSecuring the airway will have the best chance of making a positive difference in trauma patient outcomes when preceded by resuscitation and clear communication.
“Then, securing the airway will have the best chance of making a positive difference in trauma patient outcomes.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S4 (based). May combine two claims.
Interpretationnone givenAirway management in trauma begins as soon as patient contact is made and rarely starts with placement of an endotracheal tube.
“Airway management in trauma begins as soon as patient contact is made and rarely starts with placement of an ETT.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing), S4 (based).
Interpretationnone givenHemodynamic instability in trauma is most commonly caused by hypovolemia due to hemorrhage.
“Hemodynamic instability in trauma is most commonly caused by hypovolemia due to hemorrhage.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S4 (based).
Interpretationnone givenParalysis should have no direct effect on the patient's hemodynamic status.
“Paralysis should have no direct effect on the patient's hemodynamic status”
Quote in the paperNot a substantial claimClassified as probably not a substantial claim. May combine two claims.
InterpretationreasoningSuccess in trauma airway management is dependent on a shared understanding of the importance of resuscitation before intubation and clear communication of what and when various airway interventions will be performed.
“Whether the team is a doctor, nurse, and transporting paramedics or a group of 10, success is dependent on a shared understanding of the importance of resuscitation before intubation and clear communication of what and when various airway interventions will be performed.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing), S4 (based).
Premisenone givenVasopressors have traditionally been avoided in trauma based on concerns that they may worsen bleeding.
“Vasopressors have traditionally been avoided in trauma based on concerns that they may worsen bleeding.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S2 (checkable), S4 (based). May combine two claims.
Interpretationnone givenEffective trauma care requires a team approach, with resuscitation priorities clearly communicated and interventions guided by the physiologic priorities that ensure adequate oxygen delivery.
“Effective trauma care requires a team approach, with resuscitation priorities clearly communicated and interventions guided by the physiologic priorities that ensure adequate oxygen delivery.”
Quote in the paperNot a substantial claimClassified as probably not a substantial claim. May combine two claims.
Interpretationnone givenThe scalpel-bougie technique relies on gross motor skills, uses familiar equipment (scalpel, bougie, and a #6 ETT), and has a minimal number of steps.
“The scalpel-bougie technique has several advantages for the emergency clinician: it relies on gross motor skills (which are more likely to be preserved during periods of acute stress), uses familiar equipment (scalpel, bougie, and a #6 ETT), and has a minimal number of steps.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing), S4 (based).
Interpretationnone givenProviding advanced airway management is part of the A and B and C parallel resuscitative priorities of trauma care.
“Providing advanced airway management is part of the A and B and C parallel resuscitative priorities of trauma care.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S2 (checkable), S4 (based). May combine two claims.
InterpretationreasoningHaving the sick trauma patient wake up to a state that he or she will be able rescue his or her own airway is simply not realistic, and will make efforts to secure the airway even more difficult.
“Having the sick trauma patient wake up to a state that he or she will be able rescue his or her own airway is simply not realistic, and will make efforts to secure the airway even more difficult.”
Quote in the paperNot a substantial claimClassified as probably not a substantial claim.
InterpretationreasoningExtended, deep paralysis is desirable in potentially difficult airway cases, as it helps to create optimal conditions for laryngoscopy, BVM and SGA ventilation, and FONA.
“extended, deep paralysis is in fact desirable in this circumstance, as it helps to create optimal conditions for laryngoscopy, BVM and SGA ventilation, and FONA.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S4 (based).
Interpretationnone givenIntravascular depletion shifts the gradient between right atrial pressure and mean systemic pressure, reducing preload and subsequently mean arterial pressure.
“Intravascular depletion shifts the gradient between right atrial pressure Trauma Airway and mean systemic pressure, reducing preload and subsequently mean arterial pressure.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S4 (based).
Interpretationnone givenGaining intravenous access, beginning fluid resuscitation, and applying oxygen may be lifesaving and/or bridging interventions that allow for the safe execution of downstream more definitive procedures.
“Gaining intravenous access, beginning fluid resuscitation, and applying oxygen may be lifesaving and/or bridging interventions that allow for the safe execution of downstream more definitive procedures.”
Quote in the paperNot a substantial claim
The paper relies on this without support.
Traumatic brain injury (TBI) is the most common cause of mortality in trauma patients.
“Traumatic brain injury (TBI) is the most common cause of mortality in trauma patients.”
The paper relies on this without support.
Airway management in TBI patients is often performed for airway protection.
“Airway management in this cohort of patients is often performed for airway protection.”
The paper relies on this without support.
Severe or catastrophic brain injury is usually nonsurvivable, and associated with early death.
“Severe or catastrophic brain injury is usually nonsurvivable, and associated with early death.”
The authors state this as an assumption.
Structural collapse of the airway may occur during an RSI.
“Practitioners must proceed with the assumption that structural collapse of the airway may occur during an RSI.”
The paper relies on this without support.
Proceeding with an RSI in a patient who is already hypoxemic can result in catastrophic complications.
“Proceeding with an RSI in a patient who is already hypoxemic can result in catastrophic complications.”
The paper relies on this without support.
High oxygen saturation is not a true measurement of oxygen reserve.
“Although high oxygen saturation is reassuring, it is not a true measurement of oxygen reserve.”
The paper relies on this without support.
Increasing the oxygen reserve has three components: denitrogenation of the lungs, recruitment of alveoli with PEEP, and apneic oxygenation.
“Increasing the oxygen reserve has 3 components: denitrogenation of the lungs, recruitment of alveoli with PEEP, and apneic oxygenation.”
The paper relies on this without support.
Denitrogenation is the primary physiologic mechanism of preoxygenation and is dependent on delivery of a high concentration of oxygen, resulting in a 10-fold increase in available oxygen.
“Denitrogenation is the primary physiologic mechanism of preoxygenation and is dependent on delivery of a high concentration of oxygen, resulting in a 10-fold increase available oxygen.”
The paper relies on this without support.
Increased functional residual capacity provides an ongoing reservoir to keep hemoglobin saturated.
“Increased functional residual capacity (FRC) provides an ongoing reservoir to keep hemoglobin saturated.”
The paper relies on this without support.
A PEEP valve attached to a bag-valve-mask and applied over conventional nasal prongs at high flow (15 LPM) in a spontaneously breathing patient will produce continuous positive airway pressure-like conditions.
“A PEEP valve attached to a BVM and applied over conventional nasal prongs at high flow (15 LPM) in a spontaneously breathing patient will produce continuous positive airway pressure-like conditions.”
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
Each contradiction between two passages listed here was confirmed by an independent check.
Shock index is defined in opposite ways
MinorThe main text defines shock index as heart rate divided by systolic blood pressure, but the Figure 5 caption reverses the ratio. This affects interpretation of the stated risk threshold of greater than 0.8.
“Patients with a shock index (defined as heart rate divided by SBP) of greater than 0.8 are at particular risk of developing significant hypotension in the postintubation period.”
“SI: shock index (SBP/HR)”
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Vomit, Blood, and Secretions: Dealing with the Contaminated Airway in Trauma
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Acil Operasyonlar ve Anestezi Dağılım Analizi: Retrospektif Çalışma
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Clinical Diagnosis and Management of Traumatic Acute Intracranial Subdural Hematoma: Review Article
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OS AGRAVOS EM PACIENTES SUBMETIDOS À CRICOTIREOIDOSTOMIA CIRÚRGICA.
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Deprem nedenli çoklu travma hastalarına ilk yaklaşım
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Vocal Cords Detection Using Edge Detection and Machine Learning Filtration
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- Authors
- Kovacs, G., & Sowers, N.
- Affiliations
- Dalhousie University (CA)
- Corresponding author
- Kovacs, George
- Venue
- Emergency Medicine Clinics of North America
- Publisher
- Elsevier BV
- Published
- 2018-02
- Volume
- 36
- Issue
- 1
- Pages
- 61-84
- ISSN
- 0733-8627 (ISSN-L)
- OpenAlex
- W2767387972
- Cited by
- 115
- References
- 116
- Citations by year
- 2026: 9 · 2025: 14 · 2024: 16 · 2023: 19 · 2022: 18 · 2021: 13 · 2020: 14 · 2019: 9 · 2018: 2 · 2017: 1
- FWCI
- 1.57
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Emergency Medicine Clinics of North America (publishedVersion, cc-by-nc-nd)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Anesthesiology and Pain Medicine › Airway Management and Intubation Techniques
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Tracheal and airway disorders
- Health Sciences › Medicine › Emergency Medicine › Trauma and Emergency Care Studies
- Keywords
- airway management, trauma patients, polytrauma, difficult airway, endotracheal intubation, traumatic brain injury, cervical spine injury, maxillofacial trauma, airway injury
- MeSH terms
- Airway Obstruction, Craniocerebral Trauma, Humans, Intubation, Intratracheal, Wounds and Injuries, Airway Management
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