The DOI matches its Crossref record; 128 of the 128 references it cites were found in a registry or an index.
Impaired glucose tolerance, type 2 diabetes and metabolic syndrome in polycystic ovary syndrome: a systematic review and meta-analysis
Abstract
BACKGROUND Polycystic ovary syndrome (PCOS) is a common condition in reproductive-aged women associated with impaired glucose tolerance (IGT), type 2 diabetes mellitus (DM2) and the metabolic syndrome. METHODS A literature search was conducted (MEDLINE, CINAHL, EMBASE, clinical trial registries and hand-searching) identifying studies reporting prevalence or incidence of IGT, DM2 or metabolic syndrome in women with and without PCOS. Data were presented as odds ratio (OR) [95% confidence interval (CI)] with fixed- and random-effects meta-analysis by Mantel-Haenszel methods. Quality testing was based on Newcastle-Ottawa Scaling and The Cochrane Collaboration's risk of bias assessment tool. Literature searching, data abstraction and quality appraisal were performed by two investigators. RESULTS A total of 2192 studies were reviewed and 35 were selected for final analysis. Women with PCOS had increased prevalence of IGT (OR 2.48, 95% CI 1.63, 3.77; BMI-matched studies OR 2.54, 95% CI 1.44, 4.47), DM2 (OR 4.43, 95% CI 4.06, 4.82; BMI-matched studies OR 4.00, 95% CI 1.97, 8.10) and metabolic syndrome (OR 2.88, 95% CI 2.40, 3.45; BMI-matched studies OR 2.20, 95% CI 1.36, 3.56). One study assessed IGT/DM2 incidence and reported no significant differences in DM2 incidence (OR 2.07, 95% CI 0.68, 6.30). One study assessed conversion from normal glucose tolerance to IGT/DM2 (OR 2.4, 95% CI 0.7, 8.0). No studies reported metabolic syndrome incidence. CONCLUSIONS Women with PCOS had an elevated prevalence of IGT, DM2 and metabolic syndrome in both BMI and non-BMI-matched studies. Few studies have determined IGT/DM2 or metabolic syndrome incidence in women with and without PCOS and further research is required.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“In our study and in other reports, those with PCOS are scarcely informed about cardiometabolic risk factors and long-term morbidity risk including dyslipidemia, insulin resistance, pre-diabetes, diabetes and cardiovascular disease [71–73].”
From Challenges in diagnosis and health care in polycystic ovary syndrome in Canada: a patient view to improve health care (2023) · cites this paper as [72]
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“metabolic challenges most notable after this”
From Assessment and management of polycystic ovary syndrome: Summary of an evidence-based guideline (2011) · cites this paper as [11]
Experimental — accuracy not yet measuredThe cited source says what the claim attributes to it.
In the citing paper
“Presentation varies across the life span.”
From Assessment and management of polycystic ovary syndrome: Summary of an evidence-based guideline (2011) · cites this paper as [11]
The cited source says what the claim attributes to it.
In the citing paper
“PCOS is linked with increased prevalence of cardiometabolic risk factors, including dyslipidemia [10,11,12,13], hypertension [13,14,15], chronic inflammation, and impaired glucose tolerance [16,17], as well as overweight and obesity [18,19].”
From Moving beyond Weight: A Narrative Review of the Dietary and Lifestyle Management for Reducing Cardiometabolic Risk in Polycystic Ovary Syndrome (PCOS) (2023) · cites this paper as [17]
In the citing paper
“One relatively consistent finding is that obesity exacerbates the symptoms of PCOS, especially regarding the risk for development of T2D and the metabolic syndrome [76].”
From Polycystic Ovary Syndrome: Pathophysiology, Presentation, and Treatment With Emphasis on Adolescent Girls (2019) · cites this paper as [76]
In the citing paper
“fertility issues most prominent among women in their 20s and 30s”
From Assessment and management of polycystic ovary syndrome: Summary of an evidence-based guideline (2011) · cites this paper as [11]
In the citing paper
“Metabolic features of PCOS include an apparent propensity for excess weight gain, an increased prevalence of prediabetes and DM2, a 5-10-fold risk of progression from prediabetes to DM2 and a 4-7-fold risk of DM2. 11”
From Assessment and management of polycystic ovary syndrome: Summary of an evidence-based guideline (2011) · cites this paper as [11]
In the citing paper
“Metabolic features of PCOS include an apparent propensity for excess weight gain, an increased prevalence of prediabetes and DM2, a 5-10-fold risk of progression from prediabetes to DM2 and a 4-7-fold risk of DM2. 11”
From Assessment and management of polycystic ovary syndrome: Summary of an evidence-based guideline (2011) · cites this paper as [11]
In the citing paper
“Metabolic features of PCOS include an apparent propensity for excess weight gain, an increased prevalence of prediabetes and DM2, a 5-10-fold risk of progression from prediabetes to DM2 and a 4-7-fold risk of DM2. 11”
From Assessment and management of polycystic ovary syndrome: Summary of an evidence-based guideline (2011) · cites this paper as [11]
In the citing paper
“Metabolic features of PCOS include an apparent propensity for excess weight gain, an increased prevalence of prediabetes and DM2, a 5-10-fold risk of progression from prediabetes to DM2 and a 4-7-fold risk of DM2. 11”
From Assessment and management of polycystic ovary syndrome: Summary of an evidence-based guideline (2011) · cites this paper as [11]
In the citing paper
“Women with PCOS have increased Finnish Diabetes Risk Scores as well as increased risk of gestational diabetes, 24 prediabetes and DM2 11,103 - independent of, but exacerbated by, obesity.”
From Assessment and management of polycystic ovary syndrome: Summary of an evidence-based guideline (2011) · cites this paper as [11]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
1 retracted
Shaw, L. J., Bairey Merz, C. N., Azziz, R., Stanczyk, F. Z., Sopko, G., Braunstein, G. D., Kelsey, S. F., Kip, K. E., Cooper-DeHoff, R. M., Johnson, B. D., et al. (2008) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2007-0425 · Cited by 427
RetractedCochrane Handbook for Systematic Reviews of Interventions: Cochrane Book Series
(2008) · doi:10.1002/9780470712184 · Cited by 25,048
(2014) · Medical Entomology and Zoology · Cited by 17,633
Diagnosis and Classification of Diabetes Mellitus
American Diabetes Association (2010) · Diabetes Care · doi:10.2337/dc11-s062 · Cited by 14,094
Detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III)
Grundy, S. M., Becker, D. M., Clark, L. T., Cooper, R., Denke, M. A., Howard, J. L., Hunninghake, D. B., Illingworth, D. R., Luepker, R. V., McBride, P. E., et al. (2002) · Civil War Book Review · Cited by 12,198
Grundy, S. M., Cleeman, J. I., Daniels, S. R., Donato, K. A., Eckel, R. H., Franklin, B. A., Gordon, D. J., Krauss, R. M., Savage, P. J., Smith, S. C., et al. (2005) · Circulation · doi:10.1161/circulationaha.105.169404 · Cited by 11,961
Report of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus
The Expert Committee on the Diagnosis and Classification of Diabetes Mellitus* (2002) · Diabetes Care · doi:10.2337/diacare.25.2007.s5 · Cited by 10,325
The metabolic syndrome—a new worldwide definition
Alberti, K. G. M., Zimmet, P., & Shaw, J. (2005) · The Lancet · doi:10.1016/s0140-6736(05)67402-8 · Cited by 9,352
(2004) · Fertility and Sterility · doi:10.1016/j.fertnstert.2003.10.004 · Cited by 9,050
Research works printed but not linked: 3
- Centre for Evidence-Based Medicine, 2009, Evidence Based Medicine Tools, Critical Appraisal, Study Designs
- Review Manager (RevMan) [Computer program], 2008
- Zawdaki, 1992, Diagnostic criteria for polycystic ovary syndrome: Towards a rational approach, 377
Cited by
Sorted by citations
European Guidelines on cardiovascular disease prevention in clinical practice (version 2012)
Authors/Task Force Members:, Perk, J., De Backer, G., Gohlke, H., Graham, I., Reiner, Ž., Verschuren, M., Albus, C., Benlian, P., Boysen, G., et al. (2012) · European Heart Journal · doi:10.1093/eurheartj/ehs092 · Cited by 8,490
2016 European Guidelines on cardiovascular disease prevention in clinical practice
Piepoli, M. F., Hoes, A. W., Agewall, S., Albus, C., Brotons, C., Catapano, A. L., Cooney, M.-T., Corrà, U., Cosyns, B., Deaton, C., et al. (2016) · European Heart Journal · doi:10.1093/eurheartj/ehw106 · Cited by 6,457
2021 ESC Guidelines on cardiovascular disease prevention in clinical practice
Visseren, F. L. J., Mach, F., Smulders, Y. M., Carballo, D., Koskinas, K. C., Bäck, M., Benetos, A., Biffi, A., Boavida, J.-M., Capodanno, D., et al. (2021) · European Heart Journal · doi:10.1093/eurheartj/ehab484 · Cited by 6,485
Sex and Gender Differences in Risk, Pathophysiology and Complications of Type 2 Diabetes Mellitus
Kautzky-Willer, A., Harreiter, J., & Pacini, G. (2016) · Endocrine Reviews · doi:10.1210/er.2015-1137 · Cited by 2,043
Fauser, B. C. J. M., Tarlatzis, B. C., Rebar, R. W., Legro, R. S., Balen, A. H., Lobo, R., Carmina, E., Chang, J., Yildiz, B. O., Laven, J. S. E., et al. (2012) · Fertility and Sterility · doi:10.1016/j.fertnstert.2011.09.024 · Cited by 1,976
Self-citationDiamanti-Kandarakis, E., & Dunaif, A. (2012) · Endocrine Reviews · doi:10.1210/er.2011-1034 · Cited by 1,947
Legro, R. S., Arslanian, S. A., Ehrmann, D. A., Hoeger, K. M., Murad, M. H., Pasquali, R., & Welt, C. K. (2013) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2013-2350 · Cited by 1,919
Azziz, R., Carmina, E., Chen, Z., Dunaif, A., Laven, J. S. E., Legro, R. S., Lizneva, D., Natterson-Horowtiz, B., Teede, H. J., & Yildiz, B. O. (2016) · Nature Reviews Disease Primers · doi:10.1038/nrdp.2016.57 · Cited by 2,005
Polycystic ovary syndrome: etiology, pathogenesis and diagnosis
Goodarzi, M. O., Dumesic, D. A., Chazenbalk, G., & Azziz, R. (2011) · Nature Reviews Endocrinology · doi:10.1038/nrendo.2010.217 · Cited by 1,488
Dumesic, D. A., Oberfield, S. E., Stener-Victorin, E., Marshall, J. C., Laven, J. S., & Legro, R. S. (2015) · Endocrine Reviews · doi:10.1210/er.2015-1018 · Cited by 1,020
Type 2 diabetes across generations: from pathophysiology to prevention and management
Nolan, C. J., Damm, P., & Prentki, M. (2011) · The Lancet · doi:10.1016/s0140-6736(11)60614-4 · Cited by 923
National Lipid Association Recommendations for Patient-Centered Management of Dyslipidemia: Part 2
Jacobson, T. A., Maki, K. C., Orringer, C. E., Jones, P. H., Kris-Etherton, P., Sikand, G., La Forge, R., Daniels, S. R., Wilson, D. P., Morris, P. B., et al. (2015) · Journal of Clinical Lipidology · doi:10.1016/j.jacl.2015.09.002 · Cited by 784
Self-citationStepto, N. K., Cassar, S., Joham, A. E., Hutchison, S. K., Harrison, C. L., Goldstein, R. F., & Teede, H. J. (2013) · Human Reproduction · doi:10.1093/humrep/des463 · Cited by 747
Balen, A. H., Morley, L. C., Misso, M., Franks, S., Legro, R. S., Wijeyaratne, C. N., Stener-Victorin, E., Fauser, B. C. J. M., Norman, R. J., & Teede, H. (2016) · Human Reproduction Update · doi:10.1093/humupd/dmw025 · Cited by 705
Self-citationRisk factors for type 2 diabetes mellitus: An exposure-wide umbrella review of meta-analyses
Bellou, V., Belbasis, L., Tzoulaki, I., & Evangelou, E. (2018) · PLOS ONE · doi:10.1371/journal.pone.0194127 · Cited by 713
Yildiz, B. O., Bozdag, G., Yapici, Z., Esinler, I., & Yarali, H. (2012) · Human Reproduction · doi:10.1093/humrep/des232 · Cited by 704
The polycystic ovary syndrome: a position statement from the European Society of Endocrinology
Conway, G., Dewailly, D., Diamanti-Kandarakis, E., Escobar-Morreale, H. F., Franks, S., Gambineri, A., Kelestimur, F., Macut, D., Micic, D., Pasquali, R., et al. (2014) · European Journal of Endocrinology · doi:10.1530/eje-14-0253 · Cited by 676
Witchel, S. F., Oberfield, S. E., & Peña, A. S. (2019) · Journal of the Endocrine Society · doi:10.1210/js.2019-00078 · Cited by 653
Sex differences in cardiovascular risk factors and disease prevention
Appelman, Y., van Rijn, B. B., ten Haaf, M. E., Boersma, E., & Peters, S. A. E. (2015) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2015.01.027 · Cited by 588
The effect of obesity on polycystic ovary syndrome: a systematic review and meta‐analysis
Lim, S. S., Norman, R. J., Davies, M. J., & Moran, L. J. (2013) · Obesity Reviews · doi:10.1111/j.1467-789x.2012.01053.x · Cited by 539
Self-citationLipid Levels in Polycystic Ovary Syndrome: Systematic Review and Meta-Analysis
Wild, R. A., Rizzo, M., Clifton, S., & Carmina, E. (2011) · Fertility and Sterility · doi:10.1016/j.fertnstert.2010.12.027 · Cited by 477
Self-citationOsibogun, O., Ogunmoroti, O., & Michos, E. D. (2020) · Trends in Cardiovascular Medicine · doi:10.1016/j.tcm.2019.08.010 · Cited by 423
Gibson-Helm, M., Teede, H., Dunaif, A., & Dokras, A. (2016) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2016-2963 · Cited by 428
Long-term cardiometabolic disease risk in women with PCOS: a systematic review and meta-analysis
Wekker, V, van Dammen, L., Koning, A., Heida, K. Y., Painter, R. C., Limpens, J., Laven, J. S. E., Roeters van Lennep, J. E., Roseboom, T. J., & Hoek, A. (2020) · Human Reproduction Update · doi:10.1093/humupd/dmaa029 · Cited by 425
de Groot, P. C. M., Dekkers, O. M., Romijn, J. A., Dieben, S. W. M., & Helmerhorst, F. M. (2011) · Human Reproduction Update · doi:10.1093/humupd/dmr001 · Cited by 394
The Potential Implications of a PCOS Diagnosis on a Woman's Long-Term Health Using Data Linkage
Hart, R., & Doherty, D. A. (2015) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2014-3886 · Cited by 391
Kakoly, N. S., Khomami, M. B., Joham, A. E., Cooray, S. D., Misso, M. L., Norman, R. J., Harrison, C. L., Ranasinha, S., Teede, H. J., & Moran, L. J. (2018) · Human Reproduction Update · doi:10.1093/humupd/dmy007 · Cited by 384
Self-citationAssessment and management of polycystic ovary syndrome: Summary of an evidence-based guideline
Teede, H. J., Misso, M. L., Deeks, A. A., Moran, L. J., Stuckey, B. G. A., Wong, J. L. A., Norman, R. J., Costello, M. F., & Groups, O. B. O. T. G. D. (2011) · Medical Journal of Australia · doi:10.5694/mja11.10915 · Cited by 379
Self-citationTremellen, K., & Pearce, K. (2012) · Medical Hypotheses · doi:10.1016/j.mehy.2012.04.016 · Cited by 359
Teede, H. J., Joham, A. E., Paul, E., Moran, L. J., Loxton, D., Jolley, D., & Lombard, C. (2013) · Obesity · doi:10.1002/oby.20213 · Cited by 351
Self-citationRegensteiner, J. G., Golden, S., Huebschmann, A. G., Barrett-Connor, E., Chang, A. Y., Chyun, D., Fox, C. S., Kim, C., Mehta, N., Reckelhoff, J. F., et al. (2015) · Circulation · doi:10.1161/cir.0000000000000343 · Cited by 334
Novel insights in SHBG regulation and clinical implications
Simó, R., Sáez-López, C., Barbosa-Desongles, A., Hernández, C., & Selva, D. M. (2015) · Trends in Endocrinology & Metabolism · doi:10.1016/j.tem.2015.05.001 · Cited by 335
Lim, S. S., Kakoly, N. S., Tan, J. W. J., Fitzgerald, G., Bahri Khomami, M., Joham, A. E., Cooray, S. D., Misso, M. L., Norman, R. J., Harrison, C. L., et al. (2019) · Obesity Reviews · doi:10.1111/obr.12762 · Cited by 316
Self-citationCurrent Guidelines for Diagnosing PCOS
Christ, J. P., & Cedars, M. I. (2023) · Diagnostics · doi:10.3390/diagnostics13061113 · Cited by 340
Roles of oxidative stress in polycystic ovary syndrome and cancers
Zuo, T., Zhu, M., & Xu, W. (2016) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2016/8589318 · Cited by 319
Lifestyle changes in women with polycystic ovary syndrome
Moran, L. J., Hutchison, S. K., Norman, R. J., & Teede, H. J. (2011) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd007506.pub3 · Cited by 292
Self-citationComplications and challenges associated with polycystic ovary syndrome: current perspectives
Palomba, S., Santagni, S., Falbo, A., & La Sala, G. B. (2015) · International Journal of Women's Health · doi:10.2147/ijwh.s70314 · Cited by 287
Beyond fertility: polycystic ovary syndrome and long-term health
Cooney, L. G., & Dokras, A. (2018) · Fertility and Sterility · doi:10.1016/j.fertnstert.2018.08.021 · Cited by 270
Moran, L. J., Ko, H., Misso, M., Marsh, K., Noakes, M., Talbot, M., Frearson, M., Thondan, M., Stepto, N., & Teede, H. J. (2013) · Journal of the Academy of Nutrition and Dietetics · doi:10.1016/j.jand.2012.11.018 · Cited by 259
Self-citationMetabolic risk in PCOS: Phenotype and adiposity impact
Moran, L. J., Norman, R. J., & Teede, H. J. (2015) · Trends in Endocrinology & Metabolism · doi:10.1016/j.tem.2014.12.003 · Cited by 245
Self-citationSerum Vitamin D Levels and Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis
He, C., Lin, Z., Robb, S., & Ezeamama, A. (2015) · Nutrients · doi:10.3390/nu7064555 · Cited by 242
Dumesic, D. A., Akopians, A. L., Madrigal, V. K., Ramirez, E., Margolis, D. J., Sarma, M. K., Thomas, A. M., Grogan, T. R., Haykal, R., Schooler, T. A., et al. (2016) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2016-2586 · Cited by 222
Daan, N. M. P., Louwers, Y. V., Koster, M. P. H., Eijkemans, M. J. C., de Rijke, Y. B., Lentjes, E. W. G., Fauser, B. C. J. M., & Laven, J. S. E. (2014) · Fertility and Sterility · doi:10.1016/j.fertnstert.2014.08.001 · Cited by 217
Insulin resistance and PCOS: chicken or egg?
Moghetti, P., & Tosi, F. (2021) · Journal of Endocrinological Investigation · doi:10.1007/s40618-020-01351-0 · Cited by 209
Rubin, K. H., Glintborg, D., Nybo, M., Abrahamsen, B., & Andersen, M. (2017) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2017-01354 · Cited by 195
Sex hormone-binding globulin and type 2 diabetes mellitus
Le, T. N., Nestler, J. E., Strauss, J. F., & Wickham, E. P. (2012) · Trends in Endocrinology & Metabolism · doi:10.1016/j.tem.2011.09.005 · Cited by 191
The management of patients with polycystic ovary syndrome
Jayasena, C. N., & Franks, S. (2014) · Nature Reviews Endocrinology · doi:10.1038/nrendo.2014.102 · Cited by 196
Jeanes, Y. M., & Reeves, S. (2017) · Nutrition Research Reviews · doi:10.1017/s0954422416000287 · Cited by 194
The Impact of Obesity on the Incidence of Type 2 Diabetes Among Women With Polycystic Ovary Syndrome
Kakoly, N. S., Earnest, A., Teede, H. J., Moran, L. J., & Joham, A. E. (2019) · Diabetes Care · doi:10.2337/dc18-1738 · Cited by 174
Self-citationMeyer, M. L., Malek, A. M., Wild, R. A., Korytkowski, M. T., & Talbott, E. O. (2012) · Human Reproduction Update · doi:10.1093/humupd/dmr046 · Cited by 175
Self-citationDepression, anxiety and cardiometabolic risk in polycystic ovary syndrome
Cinar, N., Kizilarslanoglu, M. C., Harmanci, A., Aksoy, D. Y., Bozdag, G., Demir, B., & Yildiz, B. O. (2011) · Human Reproduction · doi:10.1093/humrep/der338 · Cited by 168
Lizneva, D., Kirubakaran, R., Mykhalchenko, K., Suturina, L., Chernukha, G., Diamond, M. P., & Azziz, R. (2016) · Fertility and Sterility · doi:10.1016/j.fertnstert.2016.07.1121 · Cited by 171
Comorbidities and complications of polycystic ovary syndrome: An overview of systematic reviews
Gilbert, E. W., Tay, C. T., Hiam, D. S., Teede, H. J., & Moran, L. J. (2018) · Clinical Endocrinology · doi:10.1111/cen.13828 · Cited by 166
Self-citationOllila, M.-M. E., West, S., Keinänen-Kiukaanniemi, S., Jokelainen, J., Auvinen, J., Puukka, K., Ruokonen, A., Järvelin, M.-R., Tapanainen, J. S., Franks, S., et al. (2017) · Human Reproduction · doi:10.1093/humrep/dew329 · Cited by 165
Deswal, R., Yadav, A., & Dang, A. S. (2018) · Systems Biology in Reproductive Medicine · doi:10.1080/19396368.2017.1410591 · Cited by 159
F. Piepoli, M. (2017) · International Journal of Behavioral Medicine · doi:10.1007/s12529-016-9583-6 · Cited by 162
Heida, K. Y., Bots, M. L., de Groot, C. J., van Dunné, F. M., Hammoud, N. M., Hoek, A., Laven, J. S., Maas, A. H., Roeters van Lennep, J. E., Velthuis, B. K., et al. (2016) · European Journal of Preventive Cardiology · doi:10.1177/2047487316659573 · Cited by 153
Shedding new light on female fertility: the role of vitamin D
Muscogiuri, G., Altieri, B., de Angelis, C., Palomba, S., Pivonello, R., Colao, A., & Orio, F. (2017) · Reviews in Endocrine and Metabolic Disorders · doi:10.1007/s11154-017-9407-2 · Cited by 142
Cardiovascular disease risk in women with PCOS
Dokras, A. (2013) · Steroids · doi:10.1016/j.steroids.2013.04.009 · Cited by 132
Orio, F., Muscogiuri, G., Nese, C., Palomba, S., Savastano, S., Tafuri, D., Colarieti, G., La Sala, G., Colao, A., & Yildiz, B. O. (2016) · European Journal of Obstetrics & Gynecology and Reproductive Biology · doi:10.1016/j.ejogrb.2016.08.026 · Cited by 126
Conway, G., Dewailly, D., Diamanti-Kandarakis, E., Escobar-Morreale, H. F., Franks, S., Gambineri, A., Kelestimur, F., Macut, D., Micic, D., Pasquali, R., et al. (2014) · European Journal of Endocrinology · doi:10.1530/eje-14-0252 · Cited by 113
Zhu, S., Zhang, B., Jiang, X., Li, Z., Zhao, S., Cui, L., & Chen, Z.-J. (2019) · Fertility and Sterility · doi:10.1016/j.fertnstert.2018.09.013 · Cited by 109
Franks, S., & Hardy, K. (2018) · Frontiers in Endocrinology · doi:10.3389/fendo.2018.00452 · Cited by 109
Puurunen, J., Piltonen, T., Morin-Papunen, L., Perheentupa, A., Järvelä, I., Ruokonen, A., & Tapanainen, J. S. (2011) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2011-0039 · Cited by 108
Yang, K., Zeng, L., Bao, T., & Ge, J. (2018) · Reproductive Biology and Endocrinology · doi:10.1186/s12958-018-0346-x · Cited by 103
Lim, S., Smith, C. A., Costello, M. F., MacMillan, F., Moran, L., & Ee, C. (2019) · BMC Endocrine Disorders · doi:10.1186/s12902-019-0434-8 · Cited by 105
Self-citationMechanisms of intergenerational transmission of polycystic ovary syndrome
Dumesic, D. A., Hoyos, L. R., Chazenbalk, G. D., Naik, R., Padmanabhan, V., & Abbott, D. H. (2020) · Reproduction · doi:10.1530/rep-19-0197 · Cited by 101
Sleep disturbances in a community-based sample of women with polycystic ovary syndrome
Moran, L. J., March, W. A., Whitrow, M. J., Giles, L. C., Davies, M. J., & Moore, V. M. (2015) · Human Reproduction · doi:10.1093/humrep/deu318 · Cited by 98
Self-citationPanidis, D., Tziomalos, K., Papadakis, E., Vosnakis, C., Chatzis, P., & Katsikis, I. (2013) · Endocrine · doi:10.1007/s12020-013-9971-5 · Cited by 93
Binge eating behaviours and food cravings in women with polycystic ovary syndrome
Jeanes, Y. M., Reeves, S., Gibson, E. L., Piggott, C., May, V. A., & Hart, K. H. (2017) · Appetite · doi:10.1016/j.appet.2016.11.010 · Cited by 85
Mechanisms IN endocrinology: metabolic syndrome through the female life cycle
Vryonidou, A., Paschou, S. A., Muscogiuri, G., Orio, F., & Goulis, D. G. (2015) · European Journal of Endocrinology · doi:10.1530/eje-15-0275 · Cited by 88
Insulin Resistance is Associated with Depression Risk in Polycystic Ovary Syndrome
Greenwood, E. A., Pasch, L. A., Cedars, M. I., Legro, R. S., Eisenberg, E., & Huddleston, H. G. (2018) · Fertility and Sterility · doi:10.1016/j.fertnstert.2018.03.009 · Cited by 88
Kahal, H., Kyrou, I., Uthman, O. A., Brown, A., Johnson, S., Wall, P. D. H., Metcalfe, A., Parr, D. G., Tahrani, A. A., & Randeva, H. S. (2020) · Sleep and Breathing · doi:10.1007/s11325-019-01835-1 · Cited by 87
The use of metformin in women with polycystic ovary syndrome: an updated review
Notaro, A. L. G., & Neto, F. T. L. (2022) · Journal of Assisted Reproduction and Genetics · doi:10.1007/s10815-022-02429-9 · Cited by 83
Harrison, C. L., Stepto, N. K., Hutchison, S. K., & Teede, H. J. (2012) · Clinical Endocrinology · doi:10.1111/j.1365-2265.2011.04160.x · Cited by 80
Kazemi Jaliseh, H., Ramezani Tehrani, F., Behboudi-Gandevani, S., Hosseinpanah, F., Khalili, D., Cheraghi, L., & Azizi, F. (2017) · Fertility and Sterility · doi:10.1016/j.fertnstert.2017.09.004 · Cited by 80
Endocrine-metabolic dysfunction in polycystic ovary syndrome: An evolutionary perspective
Dumesic, D. A., Abbott, D. H., Sanchita, S., & Chazenbalk, G. D. (2020) · Current Opinion in Endocrine and Metabolic Research · doi:10.1016/j.coemr.2020.02.013 · Cited by 76
An Update on Contraception in Polycystic Ovary Syndrome
Oguz, S. H., & Yildiz, B. O. (2021) · Endocrinology and Metabolism · doi:10.3803/enm.2021.958 · Cited by 76
Polycystic Ovarian Syndrome: Long-Term Health Consequences
Zore, T., Joshi, N., Lizneva, D., & Azziz, R. (2017) · Seminars in Reproductive Medicine · doi:10.1055/s-0037-1603096 · Cited by 72
Resistance exercise impacts lean muscle mass in women with polycystic ovary syndrome
KOGURE, G. S., MIRANDA-FURTADO, C. L., SILVA, R. C., MELO, A. S., FERRIANI, R. A., DE SÁ, M. F. S., & REIS, R. M. D. (2016) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0000000000000822 · Cited by 68
Polycystic ovary syndrome as a plausible evolutionary outcome of metabolic adaptation
Dumesic, D. A., Padmanabhan, V., Chazenbalk, G. D., & Abbott, D. H. (2022) · Reproductive Biology and Endocrinology · doi:10.1186/s12958-021-00878-y · Cited by 63
Luque-Ramírez, M., Nattero-Chávez, L., Ortiz Flores, A. E., & Escobar-Morreale, H. F. (2018) · Human Reproduction Update · doi:10.1093/humupd/dmx039 · Cited by 62
Thomson, R. L., Buckley, J. D., & Brinkworth, G. D. (2016) · BMC Women's Health · doi:10.1186/s12905-016-0292-8 · Cited by 60
Complex diseases and co-morbidities: polycystic ovary syndrome and type 2 diabetes mellitus
Rodgers, R. J., Avery, J. C., Moore, V. M., Davies, M. J., Azziz, R., Stener-Victorin, E., Moran, L. J., Robertson, S. A., Stepto, N. K., Norman, R. J., et al. (2019) · Endocrine Connections · doi:10.1530/ec-18-0502 · Cited by 60
Self-citationEffectiveness of myoinositol for polycystic ovary syndrome: a systematic review and meta-analysis
Zeng, L., & Yang, K. (2018) · Endocrine · doi:10.1007/s12020-017-1442-y · Cited by 59
Moran, L. J., Noakes, M., Clifton, P., Buckley, J., Brinkworth, G., Thomson, R., & Norman, R. J. (2019) · Nutrients · doi:10.3390/nu11030492 · Cited by 57
Self-citationLow Circulating Adiponectin Levels in Women with Polycystic Ovary Syndrome: An Updated Meta-Analysis
Li, S., Huang, X., Zhong, H., Peng, Q., Chen, S., Xie, Y., Qin, X., & Qin, A. (2014) · Tumor Biology · doi:10.1007/s13277-013-1595-0 · Cited by 58
Piltonen, T. T., Ruokojärvi, M., Karro, H., Kujanpää, L., Morin-Papunen, L., Tapanainen, J. S., Stener-Victorin, E., Sundrström-Poromaa, I., Hirschberg, A. L., Ravn, P., et al. (2019) · PLOS ONE · doi:10.1371/journal.pone.0226074 · Cited by 58
Weight management interventions in women with and without PCOS: a systematic review
Kataoka, J., Tassone, E., Misso, M., Joham, A., Stener-Victorin, E., Teede, H., & Moran, L. (2017) · Nutrients · doi:10.3390/nu9090996 · Cited by 58
Self-citationGibson-Helm, M., Dokras, A., Karro, H., Piltonen, T., & Teede, H. (2018) · Seminars in Reproductive Medicine · doi:10.1055/s-0038-1667155 · Cited by 56
Sydora, B. C., Wilke, M. S., McPherson, M., Chambers, S., Ghosh, M., & Vine, D. F. (2023) · BMC Women's Health · doi:10.1186/s12905-023-02732-2 · Cited by 60
Mizgier, M., Jarząbek-Bielecka, G., Wendland, N., Jodłowska-Siewert, E., Nowicki, M., Brożek, A., Kędzia, W., Formanowicz, D., & Opydo-Szymaczek, J. (2021) · Nutrients · doi:10.3390/nu13030896 · Cited by 56
Tassone, E., Teede, H., Dokras, A., Garad, R., & Gibson-Helm, M. (2018) · Seminars in Reproductive Medicine · doi:10.1055/s-0038-1668086 · Cited by 48
Krug, I., Giles, S., & Paganini, C. (2019) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s168944 · Cited by 50
Moran, L., Grieger, J., Mishra, G., & Teede, H. (2015) · Nutrients · doi:10.3390/nu7105419 · Cited by 49
Self-citationKahal, H., Kyrou, I., Uthman, O., Brown, A., Johnson, S., Wall, P., Metcalfe, A., Tahrani, A. A., & Randeva, H. S. (2018) · Sleep · doi:10.1093/sleep/zsy085 · Cited by 49
Evolutionary origins of polycystic ovary syndrome: An environmental mismatch disorder
Charifson, M. A., & Trumble, B. C. (2019) · Evolution, Medicine, and Public Health · doi:10.1093/emph/eoz011 · Cited by 44
Patel, R., & Shah, G. (2017) · Current Medical Research and Opinion · doi:10.1080/03007995.2017.1279597 · Cited by 47
Mario, F. M., Graff, S. K., & Spritzer, P. M. (2017) · Journal of Endocrinological Investigation · doi:10.1007/s40618-016-0570-1 · Cited by 47
Development of type 2 diabetes in adolescent girls with polycystic ovary syndrome and obesity
Hudnut‐Beumler, J., Kaar, J. L., Taylor, A., Kelsey, M. M., Nadeau, K. J., Zeitler, P., Snell‐Bergeon, J., Pyle, L., & Cree‐Green, M. (2021) · Pediatric Diabetes · doi:10.1111/pedi.13206 · Cited by 46
Metadata
- Authors
- Moran, L. J., Misso, M. L., Wild, R. A., & Norman, R. J.
- Affiliations
- Jean Hailes (AU)
- Monash University (AU)
- OU Health (US)
- The University of Adelaide (AU)
- Corresponding author
- Moran, Lisa J.
- Venue
- Human Reproduction Update
- Publisher
- Oxford University Press (OUP)
- Published
- 2010
- Volume
- 16
- Issue
- 4
- Pages
- 347-363
- ISSN
- 1355-4786 (ISSN-L)
- 1460-2369
- OpenAlex
- W2101316067
- Cited by
- 1,108
- References
- 128
- Citations by year
- 2026: 64 · 2025: 78 · 2024: 51 · 2023: 68 · 2022: 80 · 2021: 75 · 2020: 61 · 2019: 84 · 2018: 83 · 2017: 77 · 2016: 78 · 2015: 84 · 2014: 82 · 2013: 55 · 2012: 43
- FWCI
- 6.41
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Human Reproduction Update (publishedVersion)
- PubMed (publishedVersion)
- Adelaide Research & Scholarship (AR&S) (University of Adelaide) (submittedVersion)
- Topics
- Health Sciences › Medicine › Reproductive Medicine › Ovarian function and disorders
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
- Health Sciences › Medicine › Obstetrics and Gynecology › Gestational Diabetes Research and Management
- Keywords
- polycystic ovary syndrome, impaired glucose tolerance, type 2 diabetes, metabolic syndrome, prevalence, incidence, body mass index, women's health
- MeSH terms
- Diabetes Mellitus, Type 2, Female, Humans, Polycystic Ovary Syndrome, United States, Body Mass Index, Incidence, Prevalence, Glucose Intolerance, Metabolic Syndrome
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
