Physical Activity and Cognitive Vitality

Prakash, Ruchika Shaurya; Voss, Michelle W.; Erickson, Kirk I.; Kramer, Arthur F.

doi:10.1146/annurev-psych-010814-015249

Cited by 376Physical Activity and HealthDementia and Cognitive Impairment ResearchCognitive Abilities and Testing

Physical Activity and Cognitive Vitality

Open access

Prakash, Ruchika Shaurya, Voss, Michelle W., Erickson, Kirk I., Kramer, Arthur F.·2015·Annual Review of Psychology

DOI 10.1146/annurev-psych-010814-015249

Open this paper in CoChat — free account Open PDF

Abstract

We examine evidence supporting the associations among physical activity (PA), cognitive vitality, neural functioning, and the moderation of these associations by genetic factors. Prospective epidemiological studies provide evidence for PA to be associated with a modest reduction in relative risk of cognitive decline. An evaluation of the PA-cognition link across the life span provides modest support for the effect of PA on preserving and even enhancing cognitive vitality and the associated neural circuitry in older adults, with the majority of benefits seen for tasks that are supported by the prefrontal cortex and the hippocampus. The literature on children and young adults, however, is in need of well-powered randomized controlled trials. Future directions include a more sophisticated understanding of the dose-response relationship, the integration of genetic and epigenetic approaches, inclusion of multimodal imaging of brain-behavior changes, and finally the design of multimodal interventions that may yield broader improvements in cognitive function.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1146/annurev-psych-010814-015249

Cites

187 of 187 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

There is robust evidence in the general population for the potential of exercise for preserving and improving cognition.
“Whilst there is robust evidence in the general population for the potential of exercise for preserving and improving cognition [11,12,107], future adequately powered RCTs with the primary objective of improving cognition are needed.”
From Exercise as Medicine for Mental and Substance Use Disorders: A Meta-review of the Benefits for Neuropsychiatric and Cognitive Outcomes (2020) · cites this paper as [11]
Exercise generally benefits health in humans and animals and slows cognitive ageing and neurodegeneration.
“Physical exercise is generally beneficial to all aspects of human and animal health, slowing cognitive ageing and neurodegeneration1.”
From Exercise plasma boosts memory and dampens brain inflammation via clusterin (2021) · cites this paper as [1]
Aerobic exercise-induced gray-matter changes have been directly correlated with improvements in hippocampal functioning.
“In some cases, these AE-induced gray-matter changes have been directly correlated with improvements in hippocampal functioning (Prakash et al., 2015).”
From Aerobic Exercise as a Tool to Improve Hippocampal Plasticity and Function in Humans: Practical Implications for Mental Health Treatment (2016) · cites this paper as Prakash et al., 2015
Discrepancies in aerobic exercise effects on hippocampal volume may be caused by a lack of consistency in aerobic exercise protocols used or in methods of calculating hippocampal volume.
“While some RCTs have found that AE did not have an impact on hippocampal volume (Ruscheweyh et al., 2011; Scheewe et al., 2013; Krogh et al., 2014; Rosenbaum et al., 2015; Malchow et al., 2016), it is possible that such discrepancies are caused by a lack of consistency in AE protocols used (Prakash et al., 2015) or in the methods of calculating hippocampal volume (Niemann et al., 2014).”
From Aerobic Exercise as a Tool to Improve Hippocampal Plasticity and Function in Humans: Practical Implications for Mental Health Treatment (2016) · cites this paper as Prakash et al., 2015
There is a lack of consensus as to what type, intensity or length of exercise sessions has the strongest impact on the brain.
“Another issue in the conceptualization of AE treatments is the lack of consensus as to what type, intensity or length of exercise sessions has the strongest impact on the brain (Prakash et al., 2015).”
From Aerobic Exercise as a Tool to Improve Hippocampal Plasticity and Function in Humans: Practical Implications for Mental Health Treatment (2016) · cites this paper as Prakash et al., 2015

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Studies of interference in serial verbal reactions
Stroop, J. R. (1935) · Journal of Experimental Psychology · doi:10.1037/h0054651 · Cited by 18,622 · see citing works
An Integrative Theory of Prefrontal Cortex Function
Miller, E. K., & Cohen, J. D. (2001) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.24.1.167 · Cited by 12,803 · see citing works
Complex brain networks: graph theoretical analysis of structural and functional systems
Bullmore, E., & Sporns, O. (2009) · Nature Reviews Neuroscience · doi:10.1038/nrn2575 · Cited by 11,820 · see citing works
The Brain's Default Network: Anatomy, Function, and Relevance to Disease
Buckner, R. L., Andrews‐Hanna, J. R., & Schacter, D. L. (2008) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1440.011 · Cited by 9,761 · see citing works
Voxel-Based Morphometry—The Methods
Ashburner, J., & Friston, K. J. (2000) · NeuroImage · doi:10.1006/nimg.2000.0582 · Cited by 8,676 · see citing works
Effect of physical inactivity on major non-communicable diseases worldwide: An analysis of burden of disease and life expectancy
Lee, I.-M., Shiroma, E. J., Lobelo, F., Puska, P., Blair, S. N., & Katzmarzyk, P. T. (2012) · The Lancet · doi:10.1016/s0140-6736(12)61031-9 · Cited by 8,215 · see citing works
Exercise training increases size of hippocampus and improves memory
Erickson, K. I., Voss, M. W., Prakash, R. S., Basak, C., Szabo, A., Chaddock, L., Kim, J. S., Heo, S., Alves, H., White, S. M., et al. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1015950108 · Cited by 4,855 · see citing works
Self-citation
Physical Activity and Public Health: Updated Recommendation for Adults from the American College of Sports Medicine and the American Heart Association
HASKELL, W. L., LEE, I.-M., PATE, R. R., POWELL, K. E., BLAIR, S. N., FRANKLIN, B. A., MACERA, C. A., HEATH, G. W., THOMPSON, P. D., & BAUMAN, A. (2007) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0b013e3180616b27 · Cited by 4,616 · see citing works
A theory of memory retrieval.
Ratcliff, R. (1978) · Psychological Review · doi:10.1037/0033-295x.85.2.59 · Cited by 4,513 · see citing works
Prevalence of obesity and trends in body mass index among US children and adolescents, 1999-2010.
Ogden, C., Carroll, M., Kit, B., & Flegal, K. (2012) · Journal of the American Medical Association (JAMA) · doi:10.1001/jama.2012.40 · Cited by 4,128 · see citing works
Running increases cell proliferation and neurogenesis in the adult mouse dentate gyrus
van Praag, H., Kempermann, G., & Gage, F. H. (1999) · Nature Neuroscience · doi:10.1038/6368 · Cited by 3,880 · see citing works
Fitness Effects on the Cognitive Function of Older Adults: A Meta-Analytic Study
Colcombe, S., & Kramer, A. F. (2003) · Psychological Science · doi:10.1111/1467-9280.t01-1-01430 · Cited by 3,782 · see citing works
Self-citation
The Diffusion Decision Model: Theory and Data for Two-Choice Decision Tasks
Ratcliff, R., & McKoon, G. (2008) · Neural Computation · doi:10.1162/neco.2008.12-06-420 · Cited by 3,059 · see citing works
Physical Activity and Public Health in Older Adults
Nelson, M. E., Rejeski, W. J., Blair, S. N., Duncan, P. W., Judge, J. O., King, A. C., Macera, C. A., & Castaneda‐Sceppa, C. (2007) · Circulation · doi:10.1161/circulationaha.107.185650 · Cited by 2,991 · see citing works
Running enhances neurogenesis, learning, and long-term potentiation in mice
van Praag, H., Christie, B. R., Sejnowski, T. J., & Gage, F. H. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.23.13427 · Cited by 2,904 · see citing works
Regional Brain Changes in Aging Healthy Adults: General Trends, Individual Differences and Modifiers
Raz, N., Lindenberger, U., Rodrigue, K. M., Kennedy, K. M., Head, D., Williamson, A., Dahle, C., Gerstorf, D., & Acker, J. D. (2005) · Cerebral Cortex · doi:10.1093/cercor/bhi044 · Cited by 2,875 · see citing works
A neural system for error detection and compensation
Gehring, W. J., Goss, B., Coles, M. G. H., Meyer, D. E., & Donchin, E. (1993) · Psychological Science · doi:10.1111/j.1467-9280.1993.tb00586.x · Cited by 2,862 · see citing works
Functional-anatomic fractionation of the brain’s default network
Andrews-Hanna, J. R., Reidler, J. S., Sepulcre, J., Poulin, R., & Buckner, R. L. (2010) · Neuron · doi:10.1016/j.neuron.2010.02.005 · Cited by 2,767 · see citing works
Diffusion tensor MR imaging of the human brain
Pierpaoli, C., Jezzard, P., Basser, P. J., Barnett, A., & Di Chiro, G. (1996) · Radiology · doi:10.1148/radiology.201.3.8939209 · Cited by 2,664 · see citing works
Large-scale brain networks in cognition: emerging methods and principles
Bressler, S. L., & Menon, V. (2010) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2010.04.004 · Cited by 2,348 · see citing works
Aerobic Exercise Training Increases Brain Volume in Aging Humans
Colcombe, S. J., Erickson, K. I., Scalf, P. E., Kim, J. S., Prakash, R., McAuley, E., Elavsky, S., Marquez, D. X., Hu, L., & Kramer, A. F. (2006) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/61.11.1166 · Cited by 2,134 · see citing works
Self-citation
Hemispheric asymmetry reduction in older adults: the HAROLD model
Cabeza, R. (2002) · Psychology and Aging · doi:10.1037/0882-7974.17.1.85 · Cited by 2,125 · see citing works
Physical Activity and Public Health in Older Adults: Recommendation from the American College of Sports Medicine and the American Heart Association
NELSON, M. E., REJESKI, W. J., BLAIR, S. N., DUNCAN, P. W., JUDGE, J. O., KING, A. C., MACERA, C. A., & CASTANEDA-SCEPPA, C. (2007) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0b013e3180616aa2 · Cited by 2,089 · see citing works
Exercise enhances learning and hippocampal neurogenesis in aged mice
van Praag, H., Shubert, T., Zhao, C., & Gage, F. H. (2005) · The Journal of Neuroscience · doi:10.1523/jneurosci.1731-05.2005 · Cited by 2,078 · see citing works
Hemispheric asymmetry reduction in older adults: The HAROLD model.
Cabeza, R. E. L. (2002) · Psychology and Aging · doi:10.1037//0882-7974.17.1.85 · Cited by 2,054 · see citing works
Aerobic Exercise and Neurocognitive Performance: A Meta-Analytic Review of Randomized Controlled Trials
Smith, P. J., Blumenthal, J. A., Hoffman, B. M., Cooper, H., Strauman, T. A., Welsh-Bohmer, K., Browndyke, J. N., & Sherwood, A. (2010) · Psychosomatic Medicine · doi:10.1097/psy.0b013e3181d14633 · Cited by 1,714 · see citing works
Cardiovascular fitness, cortical plasticity, and aging
Colcombe, S. J., Kramer, A. F., Erickson, K. I., Scalf, P., McAuley, E., Cohen, N. J., Webb, A., Jerome, G. J., Marquez, D. X., & Elavsky, S. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0400266101 · Cited by 1,648 · see citing works
Self-citation
Effect of Physical Activity on Cognitive Function in Older Adults at Risk for Alzheimer Disease: A Randomized Trial
Lautenschlager, N. T., Cox, K. L., Flicker, L., Foster, J. K., van Bockxmeer, F. M., Xiao, J., Greenop, K. R., & Almeida, O. P. (2008) · JAMA · doi:10.1001/jama.300.9.1027 · Cited by 1,637 · see citing works
Hippocampal BDNF mediates the efficacy of exercise on synaptic plasticity and cognition
Vaynman, S., Ying, Z., & Gomez‐Pinilla, F. (2004) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2004.03720.x · Cited by 1,460 · see citing works
Relationship of Childhood Obesity to Coronary Heart Disease Risk Factors in Adulthood: The Bogalusa Heart Study
Freedman, D. S., Khan, L. K., Dietz, W. H., Srinivasan, S. R., & Berenson, G. S. (2001) · PEDIATRICS · doi:10.1542/peds.108.3.712 · Cited by 1,359 · see citing works
An in vivo correlate of exercise-induced neurogenesis in the adult dentate gyrus
Pereira, A. C., Huddleston, D. E., Brickman, A. M., Sosunov, A. A., Hen, R., McKhann, G. M., Sloan, R., Gage, F. H., Brown, T. R., & Small, S. A. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0611721104 · Cited by 1,353 · see citing works
The relationship between physical activity and cognition in children: a meta-analysis
Sibley, B. A., & Etnier, J. L. (2003) · Pediatric Exercise Science · doi:10.1123/pes.15.3.243 · Cited by 1,308 · see citing works
Cognition assessment using the NIH Toolbox
Weintraub, S., Dikmen, S. S., Heaton, R. K., Tulsky, D. S., Zelazo, P. D., Bauer, P. J., Carlozzi, N. E., Slotkin, J., Blitz, D., Wallner-Allen, K., et al. (2013) · Neurology · doi:10.1212/wnl.0b013e3182872ded · Cited by 1,287 · cited 1× · see citing works
“For example, the National Institutes of Health Cognitive Toolbox (Weintraub et al. 2013) is one attempt to identify theoretically driven cognitive measures that could be used to facilitate comparisons across studies.”
Method
Risk Factors for Alzheimer's Disease: A Prospective Analysis from the Canadian Study of Health and Aging
Lindsay, J. (2002) · American Journal of Epidemiology · doi:10.1093/aje/kwf074 · Cited by 1,261 · see citing works
Inhibitory Interneuron Deficit Links Altered Network Activity and Cognitive Dysfunction in Alzheimer Model
Verret, L., Mann, E. O., Hang, G. B., Barth, A. M. I., Cobos, I., Ho, K., Devidze, N., Masliah, E., Kreitzer, A. C., Mody, I., et al. (2012) · Cell · doi:10.1016/j.cell.2012.02.046 · Cited by 1,216 · see citing works
Physical activity and risk of cognitive decline: a meta-analysis of prospective studies
Sofi, F., Valecchi, D., Bacci, D., Abbate, R., Gensini, G. F., Casini, A., & Macchi, C. (2011) · Journal of Internal Medicine · doi:10.1111/j.1365-2796.2010.02281.x · Cited by 1,210 · see citing works
Vision assessment using the NIH Toolbox
Varma, R., McKean‐Cowdin, R., Vitale, S., Slotkin, J., & Hays, R. D. (2013) · Neurology · doi:10.1212/wnl.0b013e3182876e0a · Cited by 1,197 · see citing works
Effects of Aerobic Exercise on Mild Cognitive Impairment: A Controlled Trial
Baker, L. D., Frank, L. L., Foster-Schubert, K., Green, P. S., Wilkinson, C. W., McTiernan, A., Plymate, S. R., Fishel, M. A., Watson, G. S., Cholerton, B. A., et al. (2010) · Archives of Neurology · doi:10.1001/archneurol.2009.307 · Cited by 1,171 · cited 1× · see citing works
“…effect of aerobic exercise training on cognitive function in an MCI population that is either low in self-reported activity before the intervention (Baker et al. 2010, Gates et al. 2013, Nagamatsu et al. 2013) or relatively active at baseline (Lautenschlager et al. 2008, van Uffelen et al. 2008).”
Background
Learning causes synaptogenesis, whereas motor activity causes angiogenesis, in cerebellar cortex of adult rats.
Black, J. E., Isaacs, K. R., Anderson, B. J., Alcantara, A. A., & Greenough, W. T. (1990) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.87.14.5568 · Cited by 1,161 · see citing works
Physical activity and enhanced fitness to improve cognitive function in older people without known cognitive impairment
Angevaren, M., Aufdemkampe, G., Verhaar, H., Aleman, A., & Vanhees, L. (2008) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd005381.pub3 · Cited by 1,130 · see citing works
Physical Activity Improves Verbal and Spatial Memory in Older Adults with Probable Mild Cognitive Impairment: A 6-Month Randomized Controlled Trial
Nagamatsu, L. S., Chan, A., Davis, J. C., Beattie, B. L., Graf, P., Voss, M. W., Sharma, D., & Liu-Ambrose, T. Y. L. (2013) · Journal of Aging Research · doi:10.1155/2013/861893 · Cited by 1,090 · see citing works
Self-citation
Exercise and brain neurotrophins
Neeper, S. A., Góauctemez-Pinilla, F., Choi, J., & Cotman, C. (1995) · Nature · doi:10.1038/373109a0 · Cited by 1,066 · see citing works
Leisure-time physical activity at midlife and the risk of dementia and Alzheimer's disease
Rovio, S., Kåreholt, I., Helkala, E.-L., Viitanen, M., Winblad, B., Tuomilehto, J., Soininen, H., Nissinen, A., & Kivipelto, M. (2005) · The Lancet Neurology · doi:10.1016/s1474-4422(05)70198-8 · Cited by 1,054 · see citing works
Bridging animal and human models of exercise-induced brain plasticity
Voss, M. W., Vivar, C., Kramer, A. F., & van Praag, H. (2013) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2013.08.001 · Cited by 1,030 · see citing works
Self-citation
Circulating Insulin-Like Growth Factor I Mediates Exercise-Induced Increases in the Number of New Neurons in the Adult Hippocampus
Trejo, J. L., Carro, E., & Torres-Alemán, I. (2001) · The Journal of Neuroscience · doi:10.1523/jneurosci.21-05-01628.2001 · Cited by 1,017 · see citing works
Aerobic fitness reduces brain tissue loss in aging humans.
Colcombe, S. J., Erickson, K. I., Raz, N., Webb, A. G., Cohen, N. J., McAuley, E., & Kramer, A. F. (2003) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/58.2.m176 · Cited by 1,017 · see citing works
Self-citation
Physical activity increases mRNA for brain-derived neurotrophic factor and nerve growth factor in rat brain
Neeper, S. A., Gómez‐Pinilla, F., Choi, J., & Cotman, C. W. (1996) · Brain Research · doi:10.1016/0006-8993(96)00273-9 · Cited by 1,015 · see citing works
Aerobic fitness is associated with hippocampal volume in elderly humans
Erickson, K. I., Prakash, R. S., Voss, M. W., Chaddock, L., Hu, L., Morris, K. S., White, S. M., Wójcicki, T. R., McAuley, E., & Kramer, A. F. (2009) · Hippocampus · doi:10.1002/hipo.20547 · Cited by 1,007 · see citing works
Self-citation
Physical activity and risk of neurodegenerative disease: a systematic review of prospective evidence
Hamer, M., & Chida, Y. (2009) · Psychological Medicine · doi:10.1017/s0033291708003681 · Cited by 988 · see citing works
Evidence for a release of brain-derived neurotrophic factor from the brain during exercise
Rasmussen, P., Brassard, P., Adser, H., Pedersen, M. V., Leick, L., Hart, E., Secher, N. H., Pedersen, B. K., & Pilegaard, H. (2009) · Experimental Physiology · doi:10.1113/expphysiol.2009.048512 · Cited by 914 · see citing works
Exercise for depression
Cooney, G. M., Dwan, K., Greig, C. A., Lawlor, D. A., Rimer, J., Waugh, F. R., McMurdo, M., & Mead, G. E. (2014) · Advances in Psychiatric Treatment · doi:10.1192/apt.20.1.2 · Cited by 895 · see citing works
Physical Exercise as a Preventive or Disease-Modifying Treatment of Dementia and Brain Aging
Ahlskog, J. E., Geda, Y. E., Graff-Radford, N. R., & Petersen, R. C. (2011) · Mayo Clinic Proceedings · doi:10.4065/mcp.2011.0252 · Cited by 885 · see citing works
Neuroplasticity – Exercise-Induced Response of Peripheral Brain-Derived Neurotrophic Factor: A Systematic Review of Experimental Studies in Human Subjects
Knaepen, K., Goekint, M., Heyman, E. M., & Meeusen, R. (2010) · Sports Medicine · doi:10.2165/11534530-000000000-00000 · Cited by 882 · see citing works
VEGF is necessary for exercise‐induced adult hippocampal neurogenesis
Fabel, K., Fabel, K., Tam, B., Kaufer, D., Baiker, A., Simmons, N., Kuo, C. J., & Palmer, T. D. (2003) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2003.03041.x · Cited by 861 · see citing works
Plasticity of brain networks in a randomized intervention trial of exercise training in older adults
Voss (2010) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2010.00032 · Cited by 841 · see citing works
Effects of voluntary exercise on synaptic plasticity and gene expression in the dentate gyrus of adult male Sprague-Dawley rats in vivo
Farmer, J., Zhao, X., van Praag, H., Wodtke, K., Gage, F. H., & Christie, B. R. (2004) · Neuroscience · doi:10.1016/j.neuroscience.2003.09.029 · Cited by 836 · see citing works
Domains of physical activity and all-cause mortality: Systematic review and dose-response meta-analysis of cohort studies
Samitz, G., Egger, M., & Zwahlen, M. (2011) · International Journal of Epidemiology · doi:10.1093/ije/dyr112 · Cited by 836 · see citing works
Resistance Training and Executive Functions: A 12-Month Randomized Controlled Trial
Liu-Ambrose, T. (2010) · Archives of Internal Medicine · doi:10.1001/archinternmed.2009.494 · Cited by 775 · see citing works
Circulating Insulin-Like Growth Factor I Mediates Effects of Exercise on the Brain
Carro, E., Nuñez, A., Busiguina, S., & Torres-Aleman, I. (2000) · The Journal of Neuroscience · doi:10.1523/jneurosci.20-08-02926.2000 · Cited by 762 · see citing works
A meta-regression to examine the relationship between aerobic fitness and cognitive performance
Etnier, J. L., Nowell, P. M., Landers, D. M., & Sibley, B. A. (2006) · Brain Research Reviews · doi:10.1016/j.brainresrev.2006.01.002 · Cited by 749 · see citing works
Untitled work
(1995) · Cited by 734 · see citing works
Total daily physical activity and the risk of AD and cognitive decline in older adults
Buchman, A. S., Boyle, P. A., Yu, L., Shah, R. C., Wilson, R. S., & Bennett, D. A. (2012) · Neurology · doi:10.1212/wnl.0b013e3182535d35 · Cited by 730 · see citing works
Exercise programs for people with dementia
Forbes, D. A., Forbes, S. C., Blake, C. M., Thiessen, E., & Forbes, S. C. (2015) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd006489.pub4 · Cited by 693 · see citing works
A neuroimaging investigation of the association between aerobic fitness, hippocampal volume, and memory performance in preadolescent children
Chaddock, L., Erickson, K. I., Prakash, R. S., Kim, J. S., Voss, M. W., VanPatter, M., Pontifex, M. B., Raine, L. B., Konkel, A., Hillman, C. H., et al. (2010) · Brain Research · doi:10.1016/j.brainres.2010.08.049 · Cited by 687 · see citing works
Self-citation
The Influence of Exercise on Cognitive Abilities
Gómez‐Pinilla, F., & Hillman, C. H. (2012) · Comprehensive physiology · doi:10.1002/cphy.c110063 · Cited by 683 · see citing works
The Effects of Physical Activity and Physical Fitness on Children's Achievement and Cognitive Outcomes: A Meta-Analysis
Fedewa, A. L., & Ahn, S. (2011) · Research Quarterly for Exercise and Sport · doi:10.1080/02701367.2011.10599785 · Cited by 624 · see citing works
Hundred days of cognitive training enhance broad cognitive abilities in adulthood: findings from the COGITO study
Schmiedek (2010) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2010.00027 · Cited by 607 · see citing works
Hippocampal Plasticity in Response to Exercise in Schizophrenia
Pajonk, F.-G., Wobrock, T., Gruber, O., Scherk, H., Berner, D., Kaizl, I., Kierer, A., Müller, S., Oest, M., Meyer, T., et al. (2010) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2009.193 · Cited by 592 · see citing works
Electrophysiology of mind. Event-related brain potentials and cognition
Mulder, G. (1996) · Biological Psychology · doi:10.1016/0301-0511(96)88276-7 · Cited by 578 · see citing works
Insulin-like growth factor I interfaces with brain-derived neurotrophic factor-mediated synaptic plasticity to modulate aspects of exercise-induced cognitive function
Ding, Q., Vaynman, S., Akhavan, M., Ying, Z., & Gomez-Pinilla, F. (2006) · Neuroscience · doi:10.1016/j.neuroscience.2006.02.084 · Cited by 555 · see citing works
Running enhances spatial pattern separation in mice
Creer, D. J., Romberg, C., Saksida, L. M., van Praag, H., & Bussey, T. J. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0911725107 · Cited by 553 · see citing works
The influence of aerobic fitness on cerebral white matter integrity and cognitive function in older adults: Results of a one‐year exercise intervention
Voss, M. W., Heo, S., Prakash, R. S., Erickson, K. I., Alves, H., Chaddock, L., Szabo, A. N., Mailey, E. L., Wójcicki, T. R., White, S. M., et al. (2013) · Human Brain Mapping · doi:10.1002/hbm.22119 · Cited by 553 · see citing works
Self-citation
The Aging Hippocampus
Erickson, K. I., Miller, D. L., & Roecklein, K. A. (2011) · The Neuroscientist · doi:10.1177/1073858410397054 · Cited by 550 · see citing works
Self-citation
Aerobic exercise improves hippocampal function and increases BDNF in the serum of young adult males
Griffin, É. W., Mullally, S. L., Foley, C., Warmington, S. A., O’Mara, S. M., & Kelly, A. M. (2011) · Physiology & Behavior · doi:10.1016/j.physbeh.2011.06.005 · Cited by 543 · see citing works
Physical activity predicts gray matter volume in late adulthood: The Cardiovascular Health Study
Erickson, K. I., Raji, C. A., Lopez, O. L., Becker, J. T., Rosano, C., Newman, A. B., Gach, H. M., Thompson, P. M., Ho, A. J., & Kuller, L. H. (2010) · Neurology · doi:10.1212/wnl.0b013e3181f88359 · Cited by 508 · see citing works
Self-citation
Physical activity and memory functions: An interventional study
Ruscheweyh, R., Willemer, C., Krüger, K., Duning, T., Warnecke, T., Sommer, J., Völker, K., Ho, H. V., Mooren, F., Knecht, S., et al. (2011) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2009.08.001 · Cited by 499 · see citing works
Aerobic Fitness and Neurocognitive Function in Healthy Preadolescent Children
Hillman, C. H., Castelli, D. M., & BUCK, S. M. (2005) · Medicine & Science in Sports & Exercise · doi:10.1249/01.mss.0000176680.79702.ce · Cited by 493 · see citing works
Voluntary exercise alters the cytoarchitecture of the adult dentate gyrus by increasing cellular proliferation, dendritic complexity, and spine density
Eadie, B. D., Redila, V. A., & Christie, B. R. (2005) · Journal of Comparative Neurology · doi:10.1002/cne.20493 · Cited by 466 · see citing works
Aerobic fitness and cognitive development: Event-related brain potential and task performance indices of executive control in preadolescent children
Hillman, C. H., Buck, S. M., Themanson, J. R., Pontifex, M. B., & Castelli, D. M. (2009) · Developmental Psychology · doi:10.1037/a0014437 · Cited by 440 · see citing works
Neurobiological markers of exercise-related brain plasticity in older adults
Voss, M. W., Erickson, K. I., Prakash, R. S., Chaddock, L., Kim, J. S., Alves, H., Szabo, A., Phillips, S. M., Wójcicki, T. R., Mailey, E. L., et al. (2013) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2012.10.021 · Cited by 418 · see citing works
Self-citation
Exercise Improves Behavioral, Neurocognitive, and Scholastic Performance in Children with Attention-Deficit/Hyperactivity Disorder
Pontifex, M. B., Saliba, B. J., Raine, L. B., Picchietti, D. L., & Hillman, C. H. (2013) · The Journal of Pediatrics · doi:10.1016/j.jpeds.2012.08.036 · Cited by 417 · see citing works
Cognitive Function, Gait Speed Decline, and Comorbidities: The Health, Aging and Body Composition Study
Atkinson, H. H., Rosano, C., Simonsick, E. M., Williamson, J. D., Davis, C., Ambrosius, W. T., Rapp, S. R., Cesari, M., Newman, A. B., Harris, T. B., et al. (2007) · The Journals of Gerontology Series A · doi:10.1093/gerona/62.8.844 · Cited by 408 · see citing works
The Impact of Sustained Engagement on Cognitive Function in Older Adults: The Synapse Project
Park, D. C., Lodi-Smith, J., Drew, L., Haber, S., Hebrank, A., Bischof, G. N., & Aamodt, W. (2014) · Psychological Science · doi:10.1177/0956797613499592 · Cited by 404 · see citing works
Predictors of maintaining cognitive function in older adults: The Health ABC Study
Yaffe, K., Fiocco, A. J., Lindquist, K., Vittinghoff, E., Simonsick, E. M., Newman, A. B., Satterfield, S., Rosano, C., Rubin, S. M., Ayonayon, H. N., et al. (2009) · Neurology · doi:10.1212/wnl.0b013e3181a92c36 · Cited by 396 · see citing works
Cardiovascular fitness is associated with cognition in young adulthood
Åberg, M. A. I., Pedersen, N. L., Torén, K., Svartengren, M., Bäckstrand, B., Johnsson, T., Cooper-Kuhn, C. M., Åberg, N. D., Nilsson, M., & Kuhn, H. G. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0905307106 · Cited by 382 · see citing works
Brain‐derived neurotrophic factor functions as a metabotrophin to mediate the effects of exercise on cognition
Gómez‐Pinilla, F., Vaynman, S., & Ying, Z. (2008) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2008.06524.x · Cited by 379 · see citing works
Leisure activities and the risk of amnestic mild cognitive impairment in the elderly
Verghese, J., LeValley, A., Derby, C., Kuslansky, G., Katz, M., Hall, C., Buschke, H., & Lipton, R. B. (2006) · Neurology · doi:10.1212/01.wnl.0000202520.68987.48 · Cited by 373 · see citing works
Resistance training and functional plasticity of the aging brain: a 12-month randomized controlled trial
Liu-Ambrose, T. Y. L., Nagamatsu, L. S., Voss, M. W., Khan, K. M., & Handy, T. C. (2011) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2011.05.010 · Cited by 364 · see citing works
Self-citation
Exercise training increases mitochondrial biogenesis in the brain
Steiner, J. L., Murphy, E. A., McClellan, J. L., Carmichael, M. D., & Davis, J. M. (2011) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00343.2011 · Cited by 357 · see citing works
The effect of exercise training on cognitive function in older adults with mild cognitive impairment: a meta-analysis of randomized controlled trials.
Gates, N., Fiatarone Singh, M. A., Sachdev, P. S., & Valenzuela, M. (2013) · The American Journal of Geriatric Psychiatry · doi:10.1016/j.jagp.2013.02.018 · Cited by 355 · see citing works
Basal Ganglia Volume Is Associated with Aerobic Fitness in Preadolescent Children
Chaddock, L., Erickson, K. I., Prakash, R. S., VanPatter, M., Voss, M. W., Pontifex, M. B., Raine, L. B., Hillman, C. H., & Kramer, A. F. (2010) · Developmental Neuroscience · doi:10.1159/000316648 · Cited by 353 · see citing works
Self-citation
Physical Activity Over the Life Course and Its Association with Cognitive Performance and Impairment in Old Age
Middleton, L. E., Barnes, D. E., Lui, L., & Yaffe, K. (2010) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2010.02903.x · Cited by 339 · see citing works
Cardiorespiratory Fitness and the Flexible Modulation of Cognitive Control in Preadolescent Children
Pontifex, M. B., Raine, L. B., Johnson, C. R., Chaddock, L., Voss, M. W., Cohen, N. J., Kramer, A. F., & Hillman, C. H. (2011) · Journal of Cognitive Neuroscience · doi:10.1162/jocn.2010.21528 · Cited by 334 · see citing works
Self-citation
The effects of aging on reaction time in a signal detection task.
Ratcliff, R., Thapar, A., & McKoon, G. (2001) · Psychology and Aging · doi:10.1037/0882-7974.16.2.323 · Cited by 331 · see citing works
Running induces widespread structural alterations in the hippocampus and entorhinal cortex
Stranahan, A. M., Khalil, D., & Gould, E. (2007) · Hippocampus · doi:10.1002/hipo.20348 · Cited by 327 · see citing works
Using network science to evaluate exercise-associated brain changes in older adults.
Burdette (2010) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2010.00023 · Cited by 320 · see citing works
Exercise induces angiogenesis but does not alter movement representations within rat motor cortex
Kleim, J. A., Cooper, N. R., & VandenBerg, P. M. (2002) · Brain Research · doi:10.1016/s0006-8993(02)02239-4 · Cited by 315 · see citing works
Physical inactivity, excess adiposity and premature mortality
Katzmarzyk, P. T., Janssen, I., & Ardern, C. I. (2003) · Obesity Reviews · doi:10.1046/j.1467-789x.2003.00120.x · Cited by 315 · see citing works
The effects of aerobic activity on brain structure.
Thomas, A. G., Dennis, A., Bandettini, P. A., & Johansen-Berg, H. (2012) · Frontiers in Psychology · doi:10.3389/fpsyg.2012.00086 · Cited by 303 · see citing works
Exploring the Effects of an “Everyday” Activity Program on Executive Function and Memory in Older Adults: Experience Corps®
Carlson, M. C., Saczynski, J. S., Rebok, G. W., Seeman, T., Glass, T. A., McGill, S., Tielsch, J., Frick, K. D., Hill, J., & Fried, L. P. (2008) · The Gerontologist · doi:10.1093/geront/48.6.793 · Cited by 296 · see citing works
A Diffusion Model Analysis of the Effects of Aging in the Lexical-Decision Task.
Ratcliff, R., Thapar, A., Gómez, P., & McKoon, G. (2004) · Psychology and Aging · doi:10.1037/0882-7974.19.2.278 · Cited by 293 · see citing works
Walking or vitamin B for cognition in older adults with mild cognitive impairment? A randomised controlled trial
van Uffelen, J. G. Z., Chinapaw, M. J. M., van Mechelen, W., & Hopman-Rock, M. (2008) · British Journal of Sports Medicine · doi:10.1136/bjsm.2007.044735 · Cited by 279 · see citing works
Environmental complexity, cerebral change, and behavior.
Rosenzweig, M. R. (1966) · American Psychologist · doi:10.1037/h0023555 · Cited by 277 · see citing works
Effects of a physical training programme on cognitive function and walking efficiency in elderly persons with dementia
Kemoun, G., Thibaud, M., Roumagne, N., Carette, P., Albinet, C., Toussaint, L., Paccalin, M., & Dugué, B. (2010) · Dementia and Geriatric Cognitive Disorders · doi:10.1159/000272435 · Cited by 273 · see citing works
Untitled work
Head (2012) · doi:10.1001/archneurol.2011.845 · Cited by 267 · see citing works
Differential effects of voluntary physical exercise on behavioral and brain-derived neurotrophic factor expression deficits in Huntington’s disease transgenic mice
Pang, T. Y. C., Stam, N. C., Nithianantharajah, J., Howard, M. L., & Hannan, A. J. (2006) · Neuroscience · doi:10.1016/j.neuroscience.2006.04.013 · Cited by 265 · see citing works
Physical activity, physical fitness, and all-cause and cancer mortality: A prospective study of men and women
Kampert, J. B., Blair, S. N., Barlow, C. E., & Kohl, H. W. (1996) · Annals of Epidemiology · doi:10.1016/s1047-2797(96)00059-2 · Cited by 265 · see citing works
Does active leisure protect cognition? Evidence from a national birth cohort.
Richards, M., Hardy, R., & Wadsworth, M. E. J. (2003) · Social Science & Medicine · doi:10.1016/s0277-9536(02)00075-8 · Cited by 264 · see citing works
Physical activity and cognitive decline, the role of the apolipoprotein e4 allele
SCHUIT, A. J., M. FESKENS, E. J., LAUNER, L. J., & KROMHOUT, D. (2001) · Medicine & Science in Sports & Exercise · doi:10.1097/00005768-200105000-00015 · Cited by 261 · see citing works
Profiles of sedentary behavior in children and adolescents: the US National Health and Nutrition Examination Survey, 2001–2006
Sisson, S. B., Church, T. S., Martin, C. K., Tudor-Locke, C., Smith, S. R., Bouchard, C., Earnest, C. P., Rankinen, T., Newton, R. L., & Katzmarzyk, P. T. (2009) · International Journal of Pediatric Obesity · doi:10.3109/17477160902934777 · Cited by 259 · see citing works
EFFECTS OF EXERCISE ON MENTAL AND PHYSICAL HEALTH PARAMETERS OF PERSONS WITH SCHIZOPHRENIA
Beebe, L. H., Tian, L., Morris, N., Goodwin, A., Allen, S. S., & Kuldau, J. (2005) · Issues in Mental Health Nursing · doi:10.1080/01612840590959551 · Cited by 259 · see citing works
Physical Activity and Incident Cognitive Impairment in Elderly Persons
Etgen, T. (2010) · Archives of Internal Medicine · doi:10.1001/archinternmed.2009.498 · Cited by 252 · see citing works
Risk Factors and Preventive Interventions for Alzheimer Disease
Daviglus, M. L., Plassman, B. L., Pirzada, A., Bell, C. C., Bowen, P. E., Burke, J. R., Connolly, E. S., Dunbar‐Jacob, J. M., Granieri, E. C., McGarry, K. M., et al. (2011) · Archives of Neurology · doi:10.1001/archneurol.2011.100 · Cited by 252 · see citing works
Intact neurogenesis is required for benefits of exercise on spatial memory but not motor performance or contextual fear conditioning in C57BL/6J mice
Clark, P., Brzezinska, W. J., Thomas, M. W., Ryzhenko, N. A., Toshkov, S. A., & Rhodes, J. S. (2008) · Neuroscience · doi:10.1016/j.neuroscience.2008.06.051 · Cited by 236 · see citing works
The Implications of Cortical Recruitment and Brain Morphology for Individual Differences in Inhibitory Function in Aging Humans.
Colcombe, S. J., Kramer, A. F., Erickson, K. I., & Scalf, P. (2005) · Psychology and Aging · doi:10.1037/0882-7974.20.3.363 · Cited by 234 · see citing works
Self-citation
Age and fitness effects on EEG, ERPs, visual sensitivity, and cognition
Dustman, R. E., Emmerson, R. Y., Ruhling, R. O., Shearer, D. E., Steinhaus, L. A., Johnson, S. C., Bonekat, H. W., & Shigeoka, J. W. (1990) · Neurobiology of Aging · doi:10.1016/0197-4580(90)90545-b · Cited by 233 · see citing works
Aerobic endurance exercise benefits memory and affect in young adults.
Stroth, S., Hille, K., Spitzer, M., & Reinhardt, R. (2009) · Neuropsychological Rehabilitation · doi:10.1080/09602010802091183 · Cited by 232 · see citing works
Brain structural trajectories over the adult lifespan
Ziegler, G., Dahnke, R., Jäncke, L., Yotter, R. A., May, A., & Christian Gaser, B. (2011) · Human Brain Mapping · doi:10.1002/hbm.21374 · Cited by 229 · see citing works
Exercise and Parkinson’s: benefits for cognition and quality of life: Exercise and Parkinson’s: cognition, mood and QoL
Cruise, K. E., Bucks, R. S., Loftus, A. M., Newton, R. U., Pegoraro, R., & Thomas, M. G. (2011) · Acta Neurologica Scandinavica · doi:10.1111/j.1600-0404.2010.01338.x · Cited by 229 · see citing works
Effect of Aerobic Exercise on Cognition, Academic Achievement, and Psychosocial Function in Children: A Systematic Review of Randomized Control Trials
Lees, C., & Hopkins, J. (2013) · Preventing Chronic Disease · doi:10.5888/pcd10.130010 · Cited by 226 · see citing works
The Relationship Between Cognitive and Physical Performance: MacArthur Studies of Successful Aging
Tabbarah, M., Crimmins, E. M., & Seeman, T. E. (2002) · The Journals of Gerontology Series A · doi:10.1093/gerona/57.4.m228 · Cited by 225 · see citing works
Benefits of physical exercise on executive functions in older people with Parkinson's disease
Tanaka, K., Quadros, A. C. D., Santos, R. F., Stella, F., Gobbi, L. T. B., & Gobbi, S. (2009) · Brain and Cognition · doi:10.1016/j.bandc.2008.09.008 · Cited by 221 · see citing works
Aerobic fitness is associated with gray matter volume and white matter integrity in multiple sclerosis
Prakash, R. S., Snook, E. M., Motl, R. W., & Kramer, A. F. (2009) · Brain Research · doi:10.1016/j.brainres.2009.06.063 · Cited by 212 · see citing works
Self-citation
The Effect of Midlife Physical Activity on Cognitive Function Among Older Adults: AGES—Reykjavik Study
Chang, M., Jónsson, P. V., Snædal, J., Björnsson, S., Saczynski, J. S., Aspelund, T., Eiríksdóttir, G., Jónsdóttir, M. K., López, O. L., Harris, T. B., et al. (2010) · The Journals of Gerontology Series A · doi:10.1093/gerona/glq152 · Cited by 212 · see citing works
The effect of midlife physical activity on structural brain changes in the elderly
Rovio, S., Spulber, G., Nieminen, L. J., Niskanen, E. I., Winblad, B. G., Tuomilehto, J., Nissinen, A. M., Soininen, H. S., & Kivipelto, M. (2008) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2008.10.007 · Cited by 211 · see citing works
Effects of exercise on fitness and cognition in progressive MS: a randomized, controlled pilot trial
Briken, S., Gold, S. M., Patra, S., Vettorazzi, E., Harbs, D., Tallner, A., Ketels, G., Schulz, K., & Heesen, C. (2013) · Multiple Sclerosis Journal · doi:10.1177/1352458513507358 · Cited by 209 · see citing works
A cross-sectional examination of age and physical activity on performance and event-related brain potentials in a task switching paradigm
Hillman, C. H., Kramer, A. F., Belopolsky, A. V., & Smith, D. L. (2006) · International Journal of Psychophysiology · doi:10.1016/j.ijpsycho.2005.04.009 · Cited by 208 · see citing works
Self-citation
Aerobic Fitness and Executive Control of Relational Memory in Preadolescent Children
Chaddock, L., Hillman, C. H., BUCK, S. M., & Cohen, N. J. (2010) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0b013e3181e9af48 · Cited by 207 · see citing works
Cerebrovascular reserve: the link between fitness and cognitive function?
Davenport, M. H., Hogan, D. B., Eskes, G. A., Longman, R. S., & Poulin, M. J. (2012) · Exercise and Sport Sciences Reviews · doi:10.1097/jes.0b013e3182553430 · Cited by 196 · see citing works
Physical Activity and Executive Control: Implications for Increased Cognitive Health during Older Adulthood
Hillman, C. H., Belopolsky, A. V., Snook, E. M., Kramer, A. F., & McAuley, E. (2004) · Research Quarterly for Exercise and Sport · doi:10.1080/02701367.2004.10609149 · Cited by 194 · see citing works
Self-citation
The effects of exercise on cognition in Parkinson’s disease: a systematic review
Murray, D., Sacheli, M., Eng, J. J., & Stoessl, A. J. (2014) · Translational Neurodegeneration · doi:10.1186/2047-9158-3-5 · Cited by 193 · see citing works
Physical activity guidelines for americans midcourse report: Strategies to increase physical activity among youth
Butner, K. L. (2013) · 141st APHA Annual Meeting and Exposition (November 2 - November 6, 2013) · Cited by 191 · see citing works
Mechanisms for widespread hippocampal involvement in cognition.
Shohamy, D., & Turk-Browne, N. B. (2013) · Journal of Experimental Psychology: General · doi:10.1037/a0034461 · Cited by 187 · see citing works
The effects of an engaged lifestyle on cognitive vitality: A field experiment.
Stine‐Morrow, E. A. L., Parisi, J. M., Morrow, D. G., & Park, D. C. (2008) · Psychology and Aging · doi:10.1037/a0014341 · Cited by 183 · see citing works
The effects of encoding task on age-related differences in the functional neuroanatomy of face memory.
Grady, C. L., Bernstein, L. J., Beig, S., & Siegenthaler, A. L. (2002) · Psychology and Aging · doi:10.1037//0882-7974.17.1.7 · Cited by 181 · see citing works
Pilot Physical Activity Intervention Reduces Severity of ADHD Symptoms in Young Children
Smith, A. L., Hoza, B., Linnea, K. S., McQuade, J. D., Tomb, M. F., Vaughn, A. J., Shoulberg, E. K., & Hook, H. (2011) · Journal of Attention Disorders · doi:10.1177/1087054711417395 · Cited by 177 · see citing works
Cardiorespiratory fitness and acute aerobic exercise effects on neuroelectric and behavioral measures of action monitoring
Themanson, J. R., & Hillman, C. H. (2006) · Neuroscience · doi:10.1016/j.neuroscience.2006.04.004 · Cited by 176 · see citing works
Age, physical fitness, and attention: P3a and P3b
Pontifex, M. B., Hillman, C. H., & Polich, J. M. (2009) · Psychophysiology · doi:10.1111/j.1469-8986.2008.00782.x · Cited by 165 · see citing works
Psychomotor Speed and Functional Brain MRI 2 Years After Completing a Physical Activity Treatment
Rosano, C., Venkatraman, V. K., Guralnik, J. M., Newman, A. B., Glynn, N. W., Launer, L. J., Taylor, C. A., Williamson, J. D., Studenski, S. A., Pahor, M., et al. (2010) · The Journals of Gerontology Series A · doi:10.1093/gerona/glq038 · Cited by 165 · see citing works
The relationship of age and cardiovascular fitness to cognitive and motor processes
Hillman, C. H., Weiss, E. P., Hagberg, J. M., & Hatfield, B. D. (2002) · Psychophysiology · doi:10.1017/s0048577201393058 · Cited by 163 · see citing works
Health behaviors from early to late midlife as predictors of cognitive function: the Whitehall II study.
Sabia, S., Nabi, H., Kivimaki, M., Shipley, M. J., Marmot, M. G., & Singh-Manoux, A. (2009) · American Journal of Epidemiology · doi:10.1093/aje/kwp161 · Cited by 162 · see citing works
The influence of exercise on brain aging and dementia
Lautenschlager, N. T., Cox, K. L., & Cyarto, E. (2011) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2011.07.010 · Cited by 157 · see citing works
A review of cardiorespiratory fitness-related neuroplasticity in the aging brain
Hayes, S. M., Hayes, J. P., Cadden, M., & Verfaellie, M. (2013) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2013.00031 · Cited by 154 · see citing works
Cardiorespiratory Fitness and Attentional Control in the Aging Brain
Prakash, R. S., Voss, M. W., Erickson, K. I., Lewis, J. M., Chaddock, L., Malkowski, E., Alves, H., Kim, J., Szabo‐Reed, A. N., White, S. M., et al. (2011) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2010.00229 · Cited by 149 · see citing works
Self-citation
The DEMO Trial: A Randomized, Parallel-Group, Observer-Blinded Clinical Trial of Strength Versus Aerobic Versus Relaxation Training for Patients With Mild to Moderate Depression
Krogh, J., Saltin, B., Gluud, C. N., & Nordentoft, M. (2009) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.08m04241 · Cited by 147 · see citing works
Assessment of physical activity in middle-aged and older adults with schizophrenia
Lindamer, L. A., McKibbin, C. L., Norman, G. J., Jordan, L. S., Harrison, K. A., Abeyesinhe, S., & Patrick, K. (2008) · Schizophrenia Research · doi:10.1016/j.schres.2008.04.040 · Cited by 145 · see citing works
Physical Activity, Cognitive Activity, and Cognitive Decline in a Biracial Community Population
Sturman, M. T., Morris, M. C., Mendes de Leon, C. F., Bienias, J. L., Wilson, R. S., & Evans, D. A. (2005) · Archives of Neurology · doi:10.1001/archneur.62.11.1750 · Cited by 142 · see citing works
The effects on cognitive functions of a movement-based intervention in patients with Alzheimer's type dementia: a pilot study
Yágüez, L., Shaw, K. N., Morris, R. G., & Matthews, D. (2010) · International Journal of Geriatric Psychiatry · doi:10.1002/gps.2510 · Cited by 140 · see citing works
Cardiorespiratory fitness: A predictor of cortical plasticity in multiple sclerosis
Prakash, R. S., Snook, E. M., Erickson, K. I., Colcombe, S. J., Voss, M. W., Motl, R. W., & Kramer, A. F. (2006) · NeuroImage · doi:10.1016/j.neuroimage.2006.10.003 · Cited by 140 · see citing works
Self-citation
The brain-derived neurotrophic factor val66met polymorphism moderates an effect of physical activity on working memory performance
Erickson, K. I., Banducci, S. E., Weinstein, A. M., MacDonald, A. W., Ferrell, R. E., Halder, I., Flory, J. D., & Manuck, S. B. (2013) · Psychological Science · doi:10.1177/0956797613480367 · Cited by 134 · see citing works
Self-citation
The Role of Cognitive Ability (Intelligence) in Explaining the Association between Socioeconomic Position and Health: Evidence from the Whitehall II Prospective Cohort Study
Singh‐Manoux, A., Ferrie, J. E., Lynch, J. W., & Marmot, M. G. (2005) · American Journal of Epidemiology · doi:10.1093/aje/kwi109 · Cited by 133 · see citing works
Physical exercise as a possible strategy for brain protection: Evidence from mitochondrial-mediated mechanisms
Marques‐Aleixo, I., Oliveira, P. J., Moreira, P. I., Magalhães, J., & Ascensão, A. A. M. R. (2012) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2012.08.002 · Cited by 132 · see citing works
The effects of encoding task on age-related differences in the functional neuroanatomy of face memory.
Grady, C. L., Bernstein, L. J., Beig, S., et al. (2002) · Psychology and Aging · doi:10.1037/0882-7974.17.1.7 · Cited by 132 · see citing works
Running‐induced epigenetic and gene expression changes in the adolescent brain
Abel, J. L., & Rissman, E. F. (2012) · International Journal of Developmental Neuroscience · doi:10.1016/j.ijdevneu.2012.11.002 · Cited by 130 · see citing works
Endurance training effects on striatal D2 dopamine receptor binding and striatal dopamine metabolites in presenescent older rats
MacRae, P. G., Spirduso, W. W., Walters, J., Farrar, R. P., & Wilcox, R. E. (1987) · Psychopharmacology · doi:10.1007/bf00177922 · Cited by 128 · see citing works
Aerobic exercise prevents age-dependent cognitive decline and reduces anxiety-related behaviors in middle-aged and old rats
Pietrelli, A., López‐Costa, J. J., Goñi, R., Brusco, A., & Basso, N. (2011) · Neuroscience · doi:10.1016/j.neuroscience.2011.11.054 · Cited by 125 · see citing works
Cognitive Performance in Older Women Relative to ApoE-ε4 Genotype and Aerobic Fitness
ETNIER, J. L., CASELLI, R. J., REIMAN, E. M., ALEXANDER, G. E., SIBLEY, B. A., TESSIER, D., & MCLEMORE, E. C. (2007) · Medicine & Science in Sports & Exercise · doi:10.1249/01.mss.0000239399.85955.5e · Cited by 124 · see citing works
Physical fitness and lifetime cognitive change
Deary, I. J., Whalley, L. J., Batty, G. D., & Starr, J. M. (2006) · Neurology · doi:10.1212/01.wnl.0000238520.06958.6a · Cited by 123 · see citing works
Children are not like older adults: A diffusion model analysis of developmental changes in speeded responses
Ratcliff, R., Love, J., Thompson, C. A., & Opfer, J. E. (2011) · Child Development · doi:10.1111/j.1467-8624.2011.01683.x · Cited by 122 · see citing works
Successful Mental Health Aging: Results From a Longitudinal Study of Older Australian Men
Almeida, O. P., Norman, P. E., Hankey, G. J., Jamrozik, K. D., & Flicker, L. A. (2006) · American Journal of Geriatric Psychiatry · doi:10.1097/01.jgp.0000192486.20308.42 · Cited by 120 · see citing works
BDNF genotype moderates the relation between physical activity and depressive symptoms.
Mata, J., Thompson, R. J., & Gotlib, I. H. (2010) · Health Psychology · doi:10.1037/a0017261 · Cited by 119 · see citing works
Age-related differences in the involvement of the prefrontal cortex in attentional control
Prakash, R. S., Erickson, K. I., Colcombe, S. J., Kim, J., Voss, M. W., & Kramer, A. F. (2009) · Brain and Cognition · doi:10.1016/j.bandc.2009.07.005 · Cited by 118 · see citing works
Self-citation
Fitness and action monitoring: Evidence for improved cognitive flexibility in young adults
Themanson, J. R., Pontifex, M. B., & Hillman, C. H. (2008) · Neuroscience · doi:10.1016/j.neuroscience.2008.09.014 · Cited by 116 · see citing works
Lack of physical activity during leisure time contributes to an impaired health related quality of life in patients with schizophrenia
Vancampfort, D., Probst, M., Scheewe, T., Maurissen, K., Sweers, K., Knapen, J., & De Hert, M. (2011) · Schizophrenia Research · doi:10.1016/j.schres.2011.03.018 · Cited by 113 · see citing works
Interactive effects of physical activity and APOE-ε4 on BOLD semantic memory activation in healthy elders
Smith, J. C., Nielson, K. A., Woodard, J. L., Seidenberg, M., Durgerian, S., Antuono, P., Butts, A. M., Hantke, N. C., Lancaster, M. A., & Rao, S. M. (2010) · NeuroImage · doi:10.1016/j.neuroimage.2010.07.070 · Cited by 111 · see citing works
Exercise Fails to Improve Neurocognition in Depressed Middle-Aged and Older Adults
Hoffman, B. M., Blumenthal, J. A., Babyak, M. A., Smith, P. J., Rogers, S. D., Doraiswamy, P. M., & Sherwood, A. (2008) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0b013e31816b877c · Cited by 110 · see citing works
BDNF receptor blockade hinders the beneficial effects of exercise in a rat model of Parkinson s disease
Real, C. C., Ferreira, A. F. B., Chaves-Kirsten, G. P., Torrão, A. S., Pires, R. S., & Britto, L. R. G. (2013) · Neuroscience · doi:10.1016/j.neuroscience.2013.01.060 · Cited by 109 · see citing works
Cortical Mechanisms of Cognitive Control for Shifting Attention in Vision and Working Memory
Tamber-Rosenau, B. J., Esterman, M. S., Chiu, Y., & Yantis, S. (2011) · Journal of Cognitive Neuroscience · doi:10.1162/jocn.2011.21608 · Cited by 108 · see citing works
Impact of aerobic exercise training on cognitive functions and affect associated to the COMT polymorphism in young adults
Stroth, S., Reinhardt, R. K., Thöne, J., Hille, K., Schneider, M., Härtel, S., Weidemann, W. M., Bös, K., & Spitzer, M. (2010) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2010.08.003 · Cited by 102 · see citing works
Lifestyle and Genetic Contributions to Cognitive Decline and Hippocampal Structure and Function in Healthy Aging
Woodard, J. L., Sugarman, M. A., Nielson, K. A., Smith, J. C., Seidenberg, M., Durgerian, S., Butts, A. M., Hantke, N. C., Lancaster, M. A., & Matthews, M. A. (2012) · Current Alzheimer Research · doi:10.2174/156720512800492477 · Cited by 88 · see citing works
An examination of potential mechanisms for exercise as a treatment for depression: A pilot study
Foley, L. S., Prapavessis, H., Osuch, E. A., De Pace, J. A., Murphy, B. A., & Podolinsky, N. J. (2008) · Mental Health and Physical Activity · doi:10.1016/j.mhpa.2008.07.001 · Cited by 85 · see citing works
Neurobiological effects of physical exercise in schizophrenia: a systematic review.
Vancampfort, D., Probst, M., De Hert, M., Soundy, A., Stubbs, B., Stroobants, M., & De Herdt, A. (2014) · Disability and Rehabilitation · doi:10.3109/09638288.2013.874505 · Cited by 80 · see citing works
The effects of exercise training on [3H]-spiperone binding in rat striatum
Gilliam, P. E., Spirduso, W. W., Martin, T. P., Walters, J., Wilcox, R. E., & Farrar, R. P. (1984) · Pharmacology Biochemistry and Behavior · doi:10.1016/0091-3057(84)90008-x · Cited by 79 · see citing works
Physical activity and depression: A multiple mediation analysis
Pickett, K., Yardley, L., & Kendrick, T. (2012) · Mental health and physical activity · doi:10.1016/j.mhpa.2012.10.001 · Cited by 77 · see citing works
Voluntary Wheel Running Reverses Age-Induced Changes in Hippocampal Gene Expression
Kohman, R. A., Rodriguez‐Zas, S. L., Southey, B. R., Kelley, K. W., Dantzer, R., & Rhodes, J. S. (2011) · PLoS ONE · doi:10.1371/journal.pone.0022654 · Cited by 73 · see citing works
Cardiovascular fitness and executive control during task-switching: An ERP study
Scisco, J. L., Leynes, P. A., & Kang, J. (2008) · International Journal of Psychophysiology · doi:10.1016/j.ijpsycho.2008.02.009 · Cited by 71 · see citing works
Exercise is not beneficial and may accelerate symptom onset in a mouse model of Huntington’s disease
Potter, M. C., Yuan, C., Ottenritter, C., Mughal, M. R., & van Praag, H. (2010) · PLoS Currents · doi:10.1371/currents.rrn1201 · Cited by 68 · see citing works
Physical activity level and medial temporal health in youth at ultra high-risk for psychosis.
Mittal, V. A., Gupta, T., Orr, J. M., Pelletier‐Baldelli, A., Dean, D. J., Lunsford‐Avery, J. R., Smith, A. K., Robustelli, B. L., Leopold, D. R., & Millman, Z. B. (2013) · Journal of Abnormal Psychology · doi:10.1037/a0034085 · Cited by 58 · see citing works
The Aging Mind and Brain: Implications of Enduring Plasticity for Behavioral and Cultural Change
Reuter‐Lorenz, P. A., & Mikels, J. A. (2006) · Cambridge University Press eBooks · doi:10.1017/cbo9780511499722.014 · Cited by 50 · see citing works
Age, vascular risk, and cognitive decline in an older, British, African-Caribbean population.
Stewart, R., Prince, M., & Mann, A. (2003) · Journal of the American Geriatrics Society · doi:10.1046/j.1532-5415.2003.51504.x · Cited by 45 · see citing works
Impact of walking on life expectancy and lifetime medical expenditure: the Ohsaki Cohort Study
Nagai, M., Kuriyama, S., Kakizaki, M., Ohmori‐Matsuda, K., Sone, T., Hozawa, A., Kawado, M., Hashimoto, S., & Tsuji, I. (2011) · BMJ Open · doi:10.1136/bmjopen-2011-000240 · Cited by 31 · see citing works
Effect of physical activity on hippocampal high affinity choline uptake and muscarinic binding: a comparison between young and old F344 rats
Fordyce, D. E., & Farrar, R. P. (1991) · Brain Research · doi:10.1016/0006-8993(91)91073-a · Cited by 29 · see citing works
Physical activity and onset of depression in adolescents: A prospective study in the general population cohort TRAILS
Stavrakakis, N., Roest, A. M., Verhulst, F. C., Ormel, J., de Jonge, P., & Oldehinkel, A. J. (2013) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2013.06.005 · Cited by 28 · see citing works
Can Participation in Mental and Physical Activity Protect Cognition in Old Age?
Lautenschlager, N. T., & Cox, K. L. (2013) · JAMA Internal Medicine · doi:10.1001/jamainternmed.2013.206 · Cited by 27 · see citing works
The BDNF Val66Met polymorphism does not moderate the effect of self-reported physical activity on depressive symptoms in midlife
Gujral, S., Manuck, S. B., Ferrell, R. E., Flory, J. D., & Erickson, K. I. (2014) · Psychiatry Research · doi:10.1016/j.psychres.2014.03.028 · Cited by 26 · see citing works
Self-citation
Cortical recruitment during selective attention in multiple sclerosis: An fMRI investigation of individual differences
Prakash, R. S., Erickson, K. I., Snook, E. M., Colcombe, S. J., Motl, R. W., & Kramer, A. F. (2008) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2008.05.027 · Cited by 22 · see citing works
Self-citation
Cardiovascular fitness is associated with altered cortical glucose metabolism during working memory in ε4 carriers
Deeny, S. P., Winchester, J., Nichol, K. E., Roth, S. M., Wu, J. C., Dick, M. B., & Cotman, C. W. (2012) · Alzheimer s & Dementia · doi:10.1016/j.jalz.2011.04.010 · Cited by 19 · see citing works

Flagged first, then by citations

Research works printed but not linked: 1

[131]131. P Baltes, PA Reuter-Lorenz, F Roesler, pp. 255-76. Cambridge, UK: Cambridge Univ. Press

Sorted by citations

Exercise interventions for cognitive function in adults older than 50: a systematic review with meta-analysis
Northey, J. M., Cherbuin, N., Pumpa, K. L., Smee, D. J., & Rattray, B. (2018) · British Journal of Sports Medicine · doi:10.1136/bjsports-2016-096587 · Cited by 1,380 · see citing works
Maintenance, reserve and compensation: the cognitive neuroscience of healthy ageing
Cabeza, R., Albert, M., Belleville, S., Craik, F. I. M., Duarte, A., Grady, C. L., Lindenberger, U., Nyberg, L., Park, D. C., Reuter-Lorenz, P. A., et al. (2018) · Nature Reviews Neuroscience · doi:10.1038/s41583-018-0068-2 · Cited by 1,289 · see citing works
Physical Activity, Cognition, and Brain Outcomes: A Review of the 2018 Physical Activity Guidelines
ERICKSON, K. I., HILLMAN, C., STILLMAN, C. M., BALLARD, R. M., BLOODGOOD, B., CONROY, D. E., MACKO, R., MARQUEZ, D. X., PETRUZZELLO, S. J., & POWELL, K. E. (2019) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0000000000001936 · Cited by 1,214 · see citing works
Self-citation
The effects of acute exercise on mood, cognition, neurophysiology, and neurochemical pathways: a review.
Basso, J. C., & Suzuki, W. A. (2016) · Brain Plasticity · doi:10.3233/bpl-160040 · Cited by 911 · see citing works
Role of Inactivity in Chronic Diseases: Evolutionary Insight and Pathophysiological Mechanisms
Booth, F. W., Roberts, C. K., Thyfault, J. P., Ruegsegger, G. N., & Toedebusch, R. G. (2017) · Physiological Reviews · doi:10.1152/physrev.00019.2016 · Cited by 696 · see citing works
EPA guidance on physical activity as a treatment for severe mental illness: a meta-review of the evidence and Position Statement from the European Psychiatric Association (EPA), supported by the International Organization of Physical Therapists in Mental Health (IOPTMH)
Stubbs, B., Vancampfort, D., Hallgren, M., Firth, J., Veronese, N., Solmi, M., Brand, S., Cordes, J., Malchow, B., Gerber, M., et al. (2018) · European Psychiatry · doi:10.1016/j.eurpsy.2018.07.004 · Cited by 697 · see citing works
Exercise as Medicine for Mental and Substance Use Disorders: A Meta-review of the Benefits for Neuropsychiatric and Cognitive Outcomes
Ashdown-Franks, G., Firth, J., Carney, R., Carvalho, A. F., Hallgren, M., Koyanagi, A., Rosenbaum, S., Schuch, F. B., Smith, L., Solmi, M., et al. (2020) · Sports Medicine · doi:10.1007/s40279-019-01187-6 · Cited by 446 · see citing works
Exercise plasma boosts memory and dampens brain inflammation via clusterin
De Miguel, Z., Khoury, N., Betley, M. J., Lehallier, B., Willoughby, D., Olsson, N., Yang, A. C., Hahn, O., Lu, N., Vest, R. T., et al. (2021) · Nature · doi:10.1038/s41586-021-04183-x · Cited by 422 · see citing works
Systematic review of physical activity and cognitive development in early childhood
Carson, V., Hunter, S., Kuzik, N., Wiebe, S. A., Spence, J. C., Friedman, A., Tremblay, M. S., Slater, L., & Hinkley, T. (2016) · Journal of Science and Medicine in Sport · doi:10.1016/j.jsams.2015.07.011 · Cited by 355 · see citing works
Can physical exercise in old age improve memory and hippocampal function?
Duzel, E., van Praag, H., & Sendtner, M. (2016) · Brain · doi:10.1093/brain/awv407 · Cited by 329 · see citing works
The Utility of Cerebral Blood Flow as a Biomarker of Preclinical Alzheimer’s Disease
Hays, C. C., Zlatar, Z. Z., & Wierenga, C. E. (2016) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-015-0261-z · Cited by 213 · see citing works
Effects of Vivifrail multicomponent intervention on functional capacity: a multicentre, randomized controlled trial
Casas‐Herrero, Á., Sáez de Asteasu, M. L., Antón‐Rodrigo, I., Sánchez‐Sánchez, J. L., Montero‐Odasso, M., Marín‐Epelde, I., Ramón‐Espinoza, F., Zambom‐Ferraresi, F., Petidier‐Torregrosa, R., Elexpuru‐Estomba, J., et al. (2022) · Journal of Cachexia, Sarcopenia and Muscle · doi:10.1002/jcsm.12925 · Cited by 186 · see citing works
Aerobic Exercise as a Tool to Improve Hippocampal Plasticity and Function in Humans: Practical Implications for Mental Health Treatment
Kandola, A., Hendrikse, J., Lucassen, P. J., & Yücel, M. (2016) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2016.00373 · Cited by 155 · see citing works
“In some cases, these AE-induced gray-matter changes have been directly correlated with improvements in hippocampal functioning (Prakash et al., 2015).”
MAP training: combining meditation and aerobic exercise reduces depression and rumination while enhancing synchronized brain activity.
Alderman, B. L., Olson, R. L., Brush, C. J., & Shors, T. J. (2016) · Translational Psychiatry · doi:10.1038/tp.2015.225 · Cited by 125 · see citing works
Objectively measured physical activity and plasma metabolomics in the shanghai physical activity study
Xiao, Q., Moore, S. C., Keadle, S. K., Xiang, Y.-B., Zheng, W., Peters, T. M., Leitzmann, M. F., Ji, B.-T., Sampson, J. N., Shu, X.-O., et al. (2016) · International Journal of Epidemiology · doi:10.1093/ije/dyw033 · Cited by 82 · see citing works
Cognitive activity mediates the association between social activity and cognitive performance: A longitudinal study.
Brown, C. L., Robitaille, A., Zelinski, E. M., Dixon, R. A., Hofer, S. M., & Piccinin, A. M. (2016) · Psychology and Aging · doi:10.1037/pag0000134 · Cited by 73 · see citing works
The Association between Physical Activity and Intrinsic Capacity in Chinese Older Adults and Its Connection to Primary Care: China Health and Retirement Longitudinal Study (CHARLS)
Zhou, M., Kuang, L., & Hu, N. (2023) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph20075361 · Cited by 49 · see citing works
Self-perceptions of ageing and perceived health status: The mediating role of cognitive functioning and physical activity
Fernández-Jiménez, C., Dumitrache, C. G., Rubio, L., & Ruiz-Montero, P. J. (2024) · Ageing and Society · doi:10.1017/s0144686x22000332 · Cited by 28 · see citing works
Complicated Role of Exercise in Modulating Memory: A Discussion of the Mechanisms Involved
Ebrahimnejad, M., Azizi, P., Alipour, V., Zarrindast, M.-R., & Vaseghi, S. (2022) · Neurochemical Research · doi:10.1007/s11064-022-03552-w · Cited by 21 · see citing works
Co-expression network analysis of human tau-transgenic mice reveals protein modules associated with tau-induced pathologies
Tsumagari, K., Sato, Y., Shimozawa, A., Aoyagi, H., Okano, H., & Kuromitsu, J. (2022) · iScience · doi:10.1016/j.isci.2022.104832 · Cited by 15 · see citing works
Establishing the feasibility of exercise breaks during university lectures
Hayes, S. M. (2024) · Frontiers in Sports and Active Living · doi:10.3389/fspor.2024.1358564 · Cited by 9 · see citing works

Daily Energy Intake Distribution and Cognitive Performance in Non-Demented Individuals
Brikou, D., Charisis, S., Drouka, A., Christodoulakou, S. M., Ntanasi, E., Mamalaki, E., Constadinides, V. C., Scarmeas, N., & Yannakoulia, M. (2023) · Nutrients · doi:10.3390/nu15030673 · Cited by 7 · see citing works
Functional Link between Cognition and Action: Differences in Golf Putting Performance according to Cognitive Performance in Working Memory
교수, 계., Ha, J., Ja, D., et al. (2022) · 한국스포츠심리학회지 · doi:10.14385/kssp.33.2.53
The consequences of sleep deprivation on cognitive performance
Khan, M., & Al-Jahdali, H. H. (2023) · Neurosciences · doi:10.17712/nsj.2023.2.20220108 · Cited by 188 · see citing works
Effects of Cognitive Reserve on Cognitive Performance in a Follow-Up Study in Older Adults With Subjective Cognitive Complaints. The Role of Working Memory
Lojo‐Seoane, C., Facal-Mayo, D., Guàrdia‐Olmos, J., Pereiro, A. X., & Juncos‐Rabadán, O. (2018) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2018.00189 · Cited by 44 · see citing works
Stress-related cognitive interference predicts cognitive function in old age.
Stawski, R. S., Sliwinski, M. J., & Smyth, J. M. (2006) · Psychology and Aging · doi:10.1037/0882-7974.21.3.535 · Cited by 140 · see citing works

Authors: Prakash, R. S., Voss, M. W., Erickson, K. I., & Kramer, A. F.
Affiliations: The Ohio State University (US)
University of Iowa (US)
University of Pittsburgh (US)
University of Illinois Urbana-Champaign (US)
ORCID: Prakash, Ruchika Shaurya
Voss, Michelle W.
Erickson, Kirk I.
Kramer, Arthur F.
Venue: Annual Review of Psychology
Publisher: Annual Reviews
Published: 2015-01-03
Volume: 66
Issue: 1
Pages: 769-797
ISSN: 0066-4308 (ISSN-L)
1545-2085
DOI: 10.1146/annurev-psych-010814-015249
OpenAlex: W2127583975
Semantic Scholar: 674e4a3211b1fc0697bf3eb16c6f8b6f242b795f
Cited by: 376
References: 187
Citations by year: 2026: 12 · 2025: 24 · 2024: 22 · 2023: 36 · 2022: 43 · 2021: 36 · 2020: 34 · 2019: 33 · 2018: 35 · 2017: 43 · 2016: 41 · 2015: 16
FWCI: 3.90
Type: journal article
Language: en
Open access: bronze
doi.org
Locations: Annual Review of Psychology (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Physiology › Physical Activity and Health
Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
Social Sciences › Psychology › Experimental and Cognitive Psychology › Cognitive Abilities and Testing
Keywords: physical activity, cognitive decline, genetic moderation, epigenetics, prefrontal cortex, hippocampus, older adults, children and young adults, dose-response relationship, brain-behavior relationship, multimodal intervention
MeSH terms: Animals, Mental Disorders, Brain, Cognition, Humans, Human Development, Motor Activity

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Physical Activity and Cognitive Vitality

Abstract

Integrity signals

Claims the paper makes

Claims other papers make about this one

Self-check

Cites

Cited by

Related

Record

About these checks