Myelin in the Central Nervous System: Structure, Function, and Pathology

Emerging Roles for CSF-1 Receptor and its Ligands in the Nervous System

Chitu, V., Gokhan, Ş., Nandi, S., Mehler, M. F., & Stanley, E. R. (2016) · Trends in Neurosciences · doi:10.1016/j.tins.2016.03.005 · Cited by 362

Constitutively active Akt induces enhanced myelination in the CNS

Flores, A. I., Narayanan, S. P., Morse, E. N., Shick, H. E., Yin, X., Kidd, G., Avila, R. L., Kirschner, D. A., & Macklin, W. B. (2008) · The Journal of Neuroscience · doi:10.1523/jneurosci.0150-08.2008 · Cited by 361

CNS Myelin Sheath Lengths Are an Intrinsic Property of Oligodendrocytes

Bechler, M. E., Byrne, L., & ffrench-Constant, C. (2015) · Current Biology · doi:10.1016/j.cub.2015.07.056 · Cited by 359

Aquaporin-4–binding autoantibodies in patients with neuromyelitis optica impair glutamate transport by down-regulating EAAT2

Hinson, S. R., Roemer, S. F., Lucchinetti, C. F., Fryer, J. P., Kryzer, T. J., Chamberlain, J. L., Howe, C. L., Pittock, S. J., & Lennon, V. A. (2008) · The Journal of Experimental Medicine · doi:10.1084/jem.20081241 · Cited by 355

Homogeneity of active demyelinating lesions in established multiple sclerosis

Breij, E. C. W., Brink, B. P., Veerhuis, R., van den Berg, C., Vloet, R., Yan, R., Dijkstra, C. D., van der Valk, P., & Bö, L. (2008) · Annals of Neurology · doi:10.1002/ana.21311 · Cited by 353

Functional breakdown of the lipid bilayer of the myelin membrane in central and peripheral nervous system by disrupted galactocerebroside synthesis

Bosio, A., Binczek, E., & Stoffel, W. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.23.13280 · Cited by 348

Elevated Phosphatidylinositol 3,4,5-Trisphosphate in Glia Triggers Cell-Autonomous Membrane Wrapping and Myelination

Goebbels, S., Oltrogge, J. H., Kemper, R., Heilmann, I., Bormuth, I., Wolfer, S., Wichert, S. P., Mobius, W., Liu, X., Lappe-Siefke, C., et al. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.0219-10.2010 · Cited by 347

The CSF-1 receptor ligands IL-34 and CSF-1 exhibit distinct developmental brain expression patterns and regulate neural progenitor cell maintenance and maturation

Nandi, S., Gokhan, S., Dai, X.-M., Wei, S., Enikolopov, G., Lin, H., Mehler, M. F., & Stanley, E. R. (2012) · Developmental Biology · doi:10.1016/j.ydbio.2012.03.026 · Cited by 344

Pharmacogenetic stimulation of neuronal activity increases myelination in an axon-specific manner

Mitew, S., Gobius, I., Fenlon, L. R., McDougall, S. J., Hawkes, D., Xing, Y. L., Bujalka, H., Gundlach, A. L., Richards, L. J., Kilpatrick, T. J., et al. (2018) · Nature Communications · doi:10.1038/s41467-017-02719-2 · Cited by 343

Individual Oligodendrocytes Have Only a Few Hours in which to Generate New Myelin Sheaths In Vivo

Czopka, T., ffrench-Constant, C., & Lyons, D. A. (2013) · Developmental Cell · doi:10.1016/j.devcel.2013.05.013 · Cited by 342

Neurofascins Are Required to Establish Axonal Domains for Saltatory Conduction

Sherman, D. L., Tait, S., Melrose, S., Johnson, R., Zonta, B., Court, F. A., Macklin, W. B., Meek, S., Smith, A. J. H., Cottrell, D. F., et al. (2005) · Neuron · doi:10.1016/j.neuron.2005.10.019 · Cited by 342

Oligodendroglia: metabolic supporters of neurons

Philips, T., & Rothstein, J. D. (2017) · Journal of Clinical Investigation · doi:10.1172/jci90610 · Cited by 342

Intractable hiccup and nausea with periaqueductal lesions in neuromyelitis optica

Misu, T., Fujihara, K., Nakashima, I., Sato, S., & Itoyama, Y. (2005) · Neurology · doi:10.1212/01.wnl.0000183151.19351.82 · Cited by 341

Neuregulin and BDNF Induce a Switch to NMDA Receptor-Dependent Myelination by Oligodendrocytes

Lundgaard, I., Luzhynskaya, A., Stockley, J. H., Wang, Z., Evans, K. A., Swire, M., Volbracht, K., Gautier, H. O. B., Franklin, R. J. M., ffrench-Constant, C., et al. (2013) · PLoS Biology · doi:10.1371/journal.pbio.1001743 · Cited by 339

Chromosomal mapping of mouse myelin basic protein gene and structure and transcription of the partially deleted gene in shiverer mutant mice

ROACH, A., TAKAHASHI, N., PRAVTCHEVA, D., RUDDLE, F., & HOOD, L. (1985) · Cell · doi:10.1016/s0092-8674(85)80110-0 · Cited by 336

CNS Myelin Wrapping Is Driven by Actin Disassembly

Zuchero, J. B., Fu, M.-M., Sloan, S. A., Ibrahim, A., Olson, A., Zaremba, A., Dugas, J. C., Wienbar, S., Caprariello, A. V., Kantor, C., et al. (2015) · Developmental Cell · doi:10.1016/j.devcel.2015.06.011 · Cited by 335

Devic's neuromyelitis optica: A clinicopathological study of 8 patients

Mandler, R. N., Davis, L. E., Jeffery, D. R., & Kornfeld, M. (1993) · Annals of Neurology · doi:10.1002/ana.410340211 · Cited by 335

Induction of sodium channel clustering by oligodendrocytes

Kaplan, M. R., Meyer-Franke, A., Lambert, S., Bennett, V., Duncan, I. D., Levinson, S. R., & Barres, B. A. (1997) · Nature · doi:10.1038/386724a0 · Cited by 332

Paranodal junction formation and spermatogenesis require sulfoglycolipids

Honke, K., Hirahara, Y., Dupree, J., Suzuki, K., Popko, B., Fukushima, K., Fukushima, J., Nagasawa, T., Yoshida, N., Wada, Y., et al. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.032068299 · Cited by 331

Preferential Loss of Myelin-Associated Glycoprotein Reflects Hypoxia-Like White Matter Damage in Stroke and Inflammatory Brain Diseases

Aboul-Enein, F., Rauschka, H., Kornek, B., Stadelmann, C., Stefferl, A., Brück, W., Lucchinetti, C., Schmidbauer, M., Jellinger, K., & Lassmann, H. (2003) · Journal of Neuropathology & Experimental Neurology · doi:10.1093/jnen/62.1.25 · Cited by 330

Molecular outcomes of neuromyelitis optica (NMO)-IgG binding to aquaporin-4 in astrocytes

Hinson, S. R., Romero, M. F., Popescu, B. F. G., Lucchinetti, C. F., Fryer, J. P., Wolburg, H., Fallier-Becker, P., Noell, S., & Lennon, V. A. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1109980108 · Cited by 328

Remyelinated Lesions in Multiple Sclerosis: Magnetic Resonance Image Appearance

Barkhof, F., Brück, W., De Groot, C. J. A., Bergers, E., Hulshof, S., Geurts, J., Polman, C. H., & van der Valk, P. (2003) · Archives of Neurology · doi:10.1001/archneur.60.8.1073 · Cited by 328

The application of multifactorial cluster analysis in the staging of plaques in early multiple sclerosis. Identification and characterization of the primary demyelinating lesion

Gay, F. (1997) · Brain · doi:10.1093/brain/120.8.1461 · Cited by 326

Myelin‐associated glycoprotein (MAG): past, present and beyond

Quarles, R. H. (2007) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2006.04319.x · Cited by 326

Dependence of nodal sodium channel clustering on paranodal axoglial contact in the developing CNS

Rasband, M. N., Peles, E., Trimmer, J. S., Levinson, S. R., Lux, S. E., & Shrager, P. (1999) · The Journal of Neuroscience · doi:10.1523/jneurosci.19-17-07516.1999 · Cited by 325

Akt Signals through the Mammalian Target of Rapamycin Pathway to Regulate CNS Myelination

Narayanan, S. P., Flores, A. I., Wang, F., & Macklin, W. B. (2009) · The Journal of Neuroscience · doi:10.1523/jneurosci.0232-09.2009 · Cited by 325

The role of myelin and oligodendrocytes in axonal energy metabolism

Saab, A. S., Tzvetanova, I. D., & Nave, K.-A. (2013) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2013.09.008 · Cited by 324

Vanishing white matter disease

van der Knaap, M. S., Pronk, J. C., & Scheper, G. C. (2006) · The Lancet Neurology · doi:10.1016/s1474-4422(06)70440-9 · Cited by 324

Antibodies to native myelin oligodendrocyte glycoprotein in children with inflammatory demyelinating central nervous system disease

Brilot, F., Dale, R. C., Selter, R. C., Grummel, V., Reddy Kalluri, S., Aslam, M., Busch, V., Zhou, D., Cepok, S., & Hemmer, B. (2009) · Annals of Neurology · doi:10.1002/ana.21916 · Cited by 322

Demyelination versus remyelination in progressive multiple sclerosis

Bramow, S., Frischer, J. M., Lassmann, H., Koch-Henriksen, N., Lucchinetti, C. F., Sørensen, P. S., & Laursen, H. (2010) · Brain · doi:10.1093/brain/awq250 · Cited by 319

STED Nanoscopy Reveals the Ubiquity of Subcortical Cytoskeleton Periodicity in Living Neurons

D’Este, E., Kamin, D., Göttfert, F., El-Hady, A., & Hell, S. W. (2015) · Cell Reports · doi:10.1016/j.celrep.2015.02.007 · Cited by 316

Lipid metabolism in myelinating glial cells: lessons from human inherited disorders and mouse models

Chrast, R., Saher, G., Nave, K.-A., & Verheijen, M. H. G. (2011) · Journal of Lipid Research · doi:10.1194/jlr.r009761 · Cited by 314

Extensive cortical remyelination in patients with chronic multiple sclerosis

Albert, M., Antel, J., Brück, W., & Stadelmann, C. (2007) · Brain Pathology · doi:10.1111/j.1750-3639.2006.00043.x · Cited by 314

Epidemiology of Multiple Sclerosis: From Risk Factors to Prevention—An Update

Munger, K., & Ascherio, A. (2016) · Seminars in Neurology · doi:10.1055/s-0036-1579693 · Cited by 314

Progenitors in the adult cerebral cortex: cell cycle properties and regulation by physiological stimuli and injury

Simon, C., Götz, M., & Dimou, L. (2011) · Glia · doi:10.1002/glia.21156 · Cited by 313

Disease-specific molecular events in cortical multiple sclerosis lesions

Fischer, M. T., Wimmer, I., Höftberger, R., Gerlach, S., Haider, L., Zrzavy, T., Hametner, S., Mahad, D., Binder, C. J., Krumbholz, M., et al. (2013) · Brain · doi:10.1093/brain/awt110 · Cited by 311

Negative regulation of central nervous system myelination by polysialylated-neural cell adhesion molecule

Charles, P., Hernandez, M. P., Stankoff, B., Aigrot, M. S., Colin, C., Rougon, G., Zalc, B., & Lubetzki, C. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.100076197 · Cited by 306

Glia in mammalian development and disease

Zuchero, J. B., & Barres, B. A. (2015) · Development · doi:10.1242/dev.129304 · Cited by 304

Differential Control of Clustering of the Sodium Channels Nav1.2 and Nav1.6 at Developing CNS Nodes of Ranvier

Kaplan, M. R., Cho, M.-H., Ullian, E. M., Isom, L. L., Levinson, S. R., & Barres, B. A. (2001) · Neuron · doi:10.1016/s0896-6273(01)00266-5 · Cited by 304

PROGRESSIVE FIBRINOID DEGENERATION OF FIBRILLARY ASTROCYTES ASSOCIATED WITH MENTAL RETARDATION IN A HYDROCEPHALIC INFANT

ALEXANDER, W. S. (1949) · Brain · doi:10.1093/brain/72.3.373 · Cited by 303

Connexins Are Critical for Normal Myelination in the CNS

Menichella, D. M., Goodenough, D. A., Sirkowski, E., Scherer, S. S., & Paul, D. L. (2003) · The Journal of Neuroscience · doi:10.1523/jneurosci.23-13-05963.2003 · Cited by 303

Splice site selection in the proteolipid protein (PLP) gene transcript and primary structure of the DM-20 protein of central nervous system myelin.

Nave, K. A., Lai, C., Bloom, F. E., & Milner, R. J. (1987) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.84.16.5665 · Cited by 302

White Matter Structure Changes as Adults Learn a Second Language

Schlegel, A. A., Rudelson, J. J., & Tse, P. U. (2012) · Journal of Cognitive Neuroscience · doi:10.1162/jocn_a_00240 · Cited by 302

Central nervous system myelin: structure, synthesis and assembly

Aggarwal, S., Yurlova, L., & Simons, M. (2011) · Trends in Cell Biology · doi:10.1016/j.tcb.2011.06.004 · Cited by 301

Microglial TREM2/DAP12 signaling: a double-edged sword in neural diseases

Konishi, H., & Kiyama, H. (2018) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2018.00206 · Cited by 300

Adult ceramide synthase 2 (CERS2)-deficient mice exhibit myelin sheath defects, cerebellar degeneration, and hepatocarcinomas

Imgrund, S., Hartmann, D., Farwanah, H., Eckhardt, M., Sandhoff, R., Degen, J., Gieselmann, V., Sandhoff, K., & Willecke, K. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.031971 · Cited by 299

Cerebrovascular disease in ageing and Alzheimer’s disease

Love, S., & Miners, J. S. (2016) · Acta Neuropathologica · doi:10.1007/s00401-015-1522-0 · Cited by 299

Transcriptional and Epigenetic Regulation of Oligodendrocyte Development and Myelination in the Central Nervous System

Emery, B., & Lu, Q. R. (2015) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a020461 · Cited by 299

Patients lacking the major CNS myelin protein, proteolipid protein 1, develop length-dependent axonal degeneration in the absence of demyelination and inflammation

Garbern, J. Y., Yool, D. A., Moore, G. J., Wilds, I. B., Faulk, M. W., Klugmann, M., Nave, K.-A., Sistermans, E. A., van der Knaap, M. S., Bird, T. D., et al. (2002) · Brain · doi:10.1093/brain/awf043 · Cited by 298

Inflammatory intrathecal profiles and cortical damage in multiple sclerosis

Magliozzi, R., Howell, O. W., Nicholas, R., Cruciani, C., Castellaro, M., Romualdi, C., Rossi, S., Pitteri, M., Benedetti, M. D., Gajofatto, A., et al. (2018) · Annals of Neurology · doi:10.1002/ana.25197 · Cited by 298

Multiple sclerosis normal‐appearing white matter: Pathology–imaging correlations

Moll, N. M., Rietsch, A. M., Thomas, S., Ransohoff, A. J., Lee, J., Fox, R., Chang, A., Ransohoff, R. M., & Fisher, E. (2011) · Annals of Neurology · doi:10.1002/ana.22521 · Cited by 297

Neurofascin Is a Glial Receptor for the Paranodin/Caspr-Contactin Axonal Complex at the Axoglial Junction

Charles, P., Tait, S., Faivre-Sarrailh, C., Barbin, G., Gunn-Moore, F., Denisenko-Nehrbass, N., Guennoc, A.-M., Girault, J.-A., Brophy, P. J., & Lubetzki, C. (2002) · Current Biology · doi:10.1016/s0960-9822(01)00680-7 · Cited by 297

Oligodendroglial myelination requires astrocyte-derived lipids

Camargo, N., Goudriaan, A., van Deijk, A.-L. F., Otte, W. M., Brouwers, J. F., Lodder, H., Gutmann, D. H., Nave, K.-A., Dijkhuizen, R. M., Mansvelder, H. D., et al. (2017) · PLOS Biology · doi:10.1371/journal.pbio.1002605 · Cited by 296 · cited 1×

TREM2 regulates microglial cell activation in response to demyelination in vivo

Cantoni, C., Bollman, B., Licastro, D., Xie, M., Mikesell, R., Schmidt, R., Yuede, C. M., Galimberti, D., Olivecrona, G., Klein, R. S., et al. (2015) · Acta Neuropathologica · doi:10.1007/s00401-015-1388-1 · Cited by 296

Comparative Neuropathology of Chronic Experimental Allergic Encephalomyelitis and Multiple Sclerosis

Lassmann, H. (1983) · Schriftenreihe Neurologie / Neurology Series · doi:10.1007/978-3-642-45558-2 · Cited by 296

Gangliosides are neuronal ligands for myelin-associated glycoprotein.

Yang, L. J., Zeller, C. B., Shaper, N. L., Kiso, M., Hasegawa, A., Shapiro, R. E., & Schnaar, R. L. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.2.814 · Cited by 295

Grey Matter Pathology in Multiple Sclerosis

Vercellino, M., Plano, F., Votta, B., Mutani, R., Giordana, M. T., & Cavalla, P. (2005) · Journal of Neuropathology and Experimental Neurology · doi:10.1097/01.jnen.0000190067.20935.42 · Cited by 295

Assembly of Myelin by Association of Proteolipid Protein with Cholesterol- and Galactosylceramide-Rich Membrane Domains

Simons, M., Krämer, E.-M., Thiele, C., Stoffel, W., & Trotter, J. (2000) · The Journal of Cell Biology · doi:10.1083/jcb.151.1.143 · Cited by 293

Lesion genesis in a subset of patients with multiple sclerosis: a role for innate immunity?

Marik, C., Felts, P. A., Bauer, J., Lassmann, H., & Smith, K. J. (2007) · Brain · doi:10.1093/brain/awm236 · Cited by 292

White matter astrocytes in health and disease

Lundgaard, I., Osório, M. J., Kress, B. T., Sanggaard, S., & Nedergaard, M. (2014) · Neuroscience · doi:10.1016/j.neuroscience.2013.10.050 · Cited by 290

Remyelination occurs as extensively but more slowly in old rats compared to young rats following gliotoxin-induced CNS demyelination

Shields, S. A., Gilson, J. M., Blakemore, W. F., & Franklin, R. J. M. (1999) · Glia · doi:10.1002/(sici)1098-1136(199910)28:1<77::aid-glia9>3.0.co;2-f · Cited by 287

Insufficient OPC migration into demyelinated lesions is a cause of poor remyelination in MS and mouse models

Boyd, A., Zhang, H., & Williams, A. (2013) · Acta Neuropathologica · doi:10.1007/s00401-013-1112-y · Cited by 287

Excitability and synaptic communication within the oligodendrocyte lineage

De Biase, L. M., Nishiyama, A., & Bergles, D. E. (2010) · The Journal of Neuroscience · doi:10.1523/jneurosci.6000-09.2010 · Cited by 286

Synaptopathy connects inflammation and neurodegeneration in multiple sclerosis

Mandolesi, G., Gentile, A., Musella, A., Fresegna, D., De Vito, F., Bullitta, S., Sepman, H., Marfia, G. A., & Centonze, D. (2015) · Nature Reviews Neurology · doi:10.1038/nrneurol.2015.222 · Cited by 286

Neuromyelitis Spectrum Disorders

Weinshenker, B. G., & Wingerchuk, D. M. (2017) · Mayo Clinic Proceedings · doi:10.1016/j.mayocp.2016.12.014 · Cited by 286

Post-mortem MRI-guided sampling of multiple sclerosis brain lesions: Increased yield of active demyelinating and (p)reactive lesions

De Groot, C. J. A. (2001) · Brain · doi:10.1093/brain/124.8.1635 · Cited by 285

Microglia in steady state

Kierdorf, K., & Prinz, M. (2017) · Journal of Clinical Investigation · doi:10.1172/jci90602 · Cited by 285

A large fraction of neocortical myelin ensheathes axons of local inhibitory neurons

Micheva, K. D., Wolman, D., Mensh, B. D., Pax, E., Buchanan, J., Smith, S. J., & Bock, D. D. (2016) · eLife · doi:10.7554/elife.15784 · Cited by 282

Anti-MOG antibody: The history, clinical phenotype, and pathogenicity of a serum biomarker for demyelination

Ramanathan, S., Dale, R. C., & Brilot, F. (2016) · Autoimmunity Reviews · doi:10.1016/j.autrev.2015.12.004 · Cited by 281

Premature arrest of myelin formation in transgenic mice with increased proteolipid protein gene dosage

Readhead, C., Schneider, A., Griffiths, I., & Nave, K.-A. (1994) · Neuron · doi:10.1016/0896-6273(94)90214-3 · Cited by 280

Myelin plasticity and nervous system function

Monje, M. (2018) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-080317-061853 · Cited by 274

The Unfolded Protein Response Modulates Disease Severity in Pelizaeus-Merzbacher Disease

Southwood, C. M., Garbern, J., Jiang, W., & Gow, A. (2002) · Neuron · doi:10.1016/s0896-6273(02)01045-0 · Cited by 273

Safety and efficacy of opicinumab in acute optic neuritis (RENEW): a randomised, placebo-controlled, phase 2 trial

Cadavid, D., Balcer, L., Galetta, S., Aktas, O., Ziemssen, T., Vanopdenbosch, L., Frederiksen, J., Skeen, M., Jaffe, G. J., Butzkueven, H., et al. (2017) · The Lancet Neurology · doi:10.1016/s1474-4422(16)30377-5 · Cited by 273

Mutations in the Gene Encoding Gap Junction Protein α12 (Connexin 46.6) Cause Pelizaeus-Merzbacher–Like Disease

Uhlenberg, B., Schuelke, M., Rüschendorf, F., Ruf, N., Kaindl, A. M., Henneke, M., Thiele, H., Stoltenburg-Didinger, G., Aksu, F., Topaloğlu, H., et al. (2004) · The American Journal of Human Genetics · doi:10.1086/422763 · Cited by 271

Glial cell degeneration and hypomyelination caused by overexpression of myelin proteolipid protein gene

Kagawa, T., Ikenaka, K., Inoue, Y., Kuriyama, S., Tsujii, T., Nakao, J., Nakajima, K., Aruga, J., Okano, H., & Mikoshiba, K. (1994) · Neuron · doi:10.1016/0896-6273(94)90358-1 · Cited by 269

Oligodendrocyte precursor cells in the demyelinated multiple sclerosis spinal cord

Wolswijk, G. (2002) · Brain · doi:10.1093/brain/awf031 · Cited by 268

Case definition and classification of leukodystrophies and leukoencephalopathies

Vanderver, A., Prust, M., Tonduti, D., Mochel, F., Hussey, H. M., Helman, G., Garbern, J., Eichler, F., Labauge, P., Aubourg, P., et al. (2015) · Molecular Genetics and Metabolism · doi:10.1016/j.ymgme.2015.01.006 · Cited by 265

Distinct brain imaging characteristics of autoantibody-mediated CNS conditions and multiple sclerosis

Jurynczyk, M., Geraldes, R., Probert, F., Woodhall, M. R., Waters, P., Tackley, G., DeLuca, G., Chandratre, S., Leite, M. I., Vincent, A., et al. (2017) · Brain · doi:10.1093/brain/aww350 · Cited by 265

Stability of the Myelin Membrane: Lipid molecules may impart stability to the myelin membrane through intermolecular cohesion.

O'Brien, J. S. (1965) · Science · doi:10.1126/science.147.3662.1099 · Cited by 264

Experimental allergic encephalomyelitis: A misleading model of multiple sclerosis

Sriram, S., & Steiner, I. (2005) · Annals of Neurology · doi:10.1002/ana.20743 · Cited by 264

Activation of the Mammalian Target of Rapamycin (mTOR) Is Essential for Oligodendrocyte Differentiation

Tyler, W. A., Gangoli, N., Gokina, P., Kim, H. A., Covey, M., Levison, S. W., & Wood, T. L. (2009) · The Journal of Neuroscience · doi:10.1523/jneurosci.0234-09.2009 · Cited by 263

Ciliary Neurotrophic Factor (CNTF) Enhances Myelin Formation: A Novel Role for CNTF and CNTF-Related Molecules

Stankoff, B., Aigrot, M.-S., Noël, F., Wattilliaux, A., Zalc, B., & Lubetzki, C. (2002) · The Journal of Neuroscience · doi:10.1523/jneurosci.22-21-09221.2002 · Cited by 262

GFAP mutations, age at onset, and clinical subtypes in Alexander disease

Prust, M., Wang, J., Morizono, H., Messing, A., Brenner, M., Gordon, E., Hartka, T., Sokohl, A., Schiffmann, R., Gordish-Dressman, H., et al. (2011) · Neurology · doi:10.1212/wnl.0b013e3182309f72 · Cited by 262

Colony-stimulating factor 1 receptor (CSF1R) signaling in injured neurons facilitates protection and survival

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Childhood ataxia with diffuse central nervous system hypomyelination

Schiffmann, R., Moller, J. R., Trapp, B. D., Shih, H. H., Farrer, R. G., Katz, D. A., Alger, J. R., Parker, C. C., Hauer, P. E., Kaneski, C. R., et al. (1994) · Annals of Neurology · doi:10.1002/ana.410350314 · Cited by 261

NG 2‐glia and their functions in the central nervous system

Dimou, L., & Gallo, V. (2015) · Glia · doi:10.1002/glia.22859 · Cited by 260

Connexin 47 (Cx47)-Deficient Mice with Enhanced Green Fluorescent Protein Reporter Gene Reveal Predominant Oligodendrocytic Expression of Cx47 and Display Vacuolized Myelin in the CNS

Odermatt, B., Wellershaus, K., Wallraff, A., Seifert, G., Degen, J., Euwens, C., Fuss, B., Büssow, H., Schilling, K., Steinhäuser, C., et al. (2003) · The Journal of Neuroscience · doi:10.1523/jneurosci.23-11-04549.2003 · Cited by 260

Metabolism and functions of lipids in myelin

Schmitt, S., Cantuti Castelvetri, L., & Simons, M. (2015) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2014.12.016 · Cited by 259

Myelin dynamics: protecting and shaping neuronal functions

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