Mood, food, and obesity
Open accessAbstract
Food is a potent natural reward and food intake is a complex process. Reward and gratification associated with food consumption leads to dopamine (DA) production, which in turn activates reward and pleasure centers in the brain. An individual will repeatedly eat a particular food to experience this positive feeling of gratification. This type of repetitive behavior of food intake leads to the activation of brain reward pathways that eventually overrides other signals of satiety and hunger. Thus, a gratification habit through a favorable food leads to overeating and morbid obesity. Overeating and obesity stems from many biological factors engaging both central and peripheral systems in a bi-directional manner involving mood and emotions. Emotional eating and altered mood can also lead to altered food choice and intake leading to overeating and obesity. Research findings from human and animal studies support a two-way link between three concepts, mood, food, and obesity. The focus of this article is to provide an overview of complex nature of food intake where various biological factors link mood, food intake, and brain signaling that engages both peripheral and central nervous system signaling pathways in a bi-directional manner in obesity.
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Anxiety and depressive symptoms are each associated with a host of negative health outcomes, including disordered eating and worsened health status.
“Anxiety and depressive symptoms are also each associated with a host of negative health outcomes (Niles & O’Donovan, 2019), including disordered eating (Singh, 2014) and worsened health status (e.g., Graham-Engeland et al., 2018).”
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- Authors
- Singh, M.
- Affiliations
- University of Iowa (US)
- Corresponding author
- Singh, Minati
- ORCID
- Singh, Minati
- Venue
- Frontiers in Psychology
- Publisher
- Frontiers Media SA
- Published
- 2014-09-01
- Volume
- 5
- Pages
- 925-925
- ISSN
- 1664-1078 (ISSN-L)
- PMC
- PMC4150387
- OpenAlex
- W2020362261
- Cited by
- 337
- References
- 40
- Citations by year
- 2026: 10 · 2025: 13 · 2024: 23 · 2023: 23 · 2022: 42 · 2021: 42 · 2020: 35 · 2019: 23 · 2018: 33 · 2017: 32 · 2016: 34 · 2015: 26 · 2014: 1
- FWCI
- 15.12
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- cc-by
- Locations
- Frontiers in Psychology (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- Howard Hughes Medical Institute
- Topics
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Regulation of Appetite and Obesity
- Social Sciences › Psychology › Clinical Psychology › Eating Disorders and Behaviors
- Health Sciences › Nursing › Nutrition and Dietetics › Nutrition, Health and Food Behavior
- Keywords
- mood, dietary intake, obesity, emotional eating, food reward, dopamine, brain reward system, satiety, hunger signals, overeating, food choice
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