Cited by 56Neuroendocrine regulation and behaviorNeurotransmitter Receptor Influence on BehaviorAutism Spectrum Disorder Research

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The neurobiology of social play behaviour: Past, present and future

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Achterberg, E.J. Marijke, Vanderschuren, Louk J.M.J.·2023·Neuroscience & Biobehavioral Reviews

DOI 10.1016/j.neubiorev.2023.105319

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Abstract

Social play behaviour is a highly energetic and rewarding activity that is of great importance for the development of brain and behaviour. Social play is abundant during the juvenile and early adolescent phases of life, and it occurs in most mammalian species, as well as in certain birds and reptiles. To date, the majority of research into the neural mechanisms of social play behaviour has been performed in male rats. In the present review we summarize studies on the neurobiology of social play behaviour in rats, including work on pharmacological and genetic models for autism spectrum disorders, early life manipulations and environmental factors that influence play in rats. We describe several recent developments that expand the field, and highlight outstanding questions that may guide future studies.

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“Next to that, social play is modulated differently in males and females by septal dopamine and vasopressin (Bredewold et al., 2018; Veenema et al., 2013).”
Influential
Social play experience in juvenile rats is indispensable for appropriate socio-sexual behavior in adulthood in males but not females
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See all 56

Authors: Achterberg, E. J. M., & Vanderschuren, L. J. M. J.
Affiliations: Utrecht University (NL)
Corresponding author: Achterberg, E.J. Marijke
Vanderschuren, Louk J.M.J.
ORCID: Achterberg, E.J. Marijke
Vanderschuren, Louk J.M.J.
Venue: Neuroscience & Biobehavioral Reviews
Publisher: Elsevier BV
Published: 2023-09
Volume: 152
Pages: 105319
ISSN: 0149-7634 (ISSN-L)
DOI: 10.1016/j.neubiorev.2023.105319
OpenAlex: W4384283590
Cited by: 56
References: 239
Citations by year: 2026: 11 · 2025: 17 · 2024: 25 · 2023: 3
FWCI: 2.73
Type: journal article
Language: en
Open access: hybrid
doi.org
Licence: cc-by
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
creativecommons.org/licenses/by/4.0/ (vor)
Locations: Neuroscience & Biobehavioral Reviews (publishedVersion, cc-by)
PubMed (publishedVersion)
Utrecht University Repository (Utrecht University) (submittedVersion, other-oa)
Funders: Nederlandse Organisatie voor Wetenschappelijk Onderzoek
Topics: Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Neuroendocrine regulation and behavior
Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
Keywords: rats, pharmacological models, genetic models, early life experience, environmental enrichment, juvenile development, brain development, social behavior
MeSH terms: Animals, Brain, Male, Mammals, Social Behavior, Rats

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The neurobiology of social play behaviour: Past, present and future

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