Smart micro/nanoparticles in stimulus-responsive drug/gene delivery systems

The rise of graphene

Geim, A. K., & Novoselov, K. S. (2007) · Nature Materials · doi:10.1038/nmat1849 · Cited by 39,979

Processable aqueous dispersions of graphene nanosheets

Li, D., Müller, M. B., Gilje, S., Kaner, R. B., & Wallace, G. G. (2008) · Nature Nanotechnology · doi:10.1038/nnano.2007.451 · Cited by 9,114

Nanostructured materials for advanced energy conversion and storage devices

Aricò, A. S., Bruce, P., Scrosati, B., Tarascon, J.-M., & van Schalkwijk, W. (2005) · Nature Materials · doi:10.1038/nmat1368 · Cited by 8,826

Detection of individual gas molecules adsorbed on graphene

Schedin, F., Geim, A. K., Morozov, S. V., Hill, E. W., Blake, P., Katsnelson, M. I., & Novoselov, K. S. (2007) · Nature Materials · doi:10.1038/nmat1967 · Cited by 8,028

Stimuli-responsive nanocarriers for drug delivery

Mura, S., Nicolas, J., & Couvreur, P. (2013) · Nature Materials · doi:10.1038/nmat3776 · Cited by 6,289

Redox environment of the cell as viewed through the redox state of the glutathione disulfide/glutathione couple

Schafer, F. Q., & Buettner, G. R. (2001) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(01)00480-4 · Cited by 4,587

Cancer nanotechnology: opportunities and challenges

Ferrari, M. (2005) · Nature Reviews Cancer · doi:10.1038/nrc1566 · Cited by 4,558

The Biology of Cancer: Metabolic Reprogramming Fuels Cell Growth and Proliferation

DeBerardinis, R. J., Lum, J. J., Hatzivassiliou, G., & Thompson, C. B. (2008) · Cell Metabolism · doi:10.1016/j.cmet.2007.10.002 · Cited by 4,088

Environment-sensitive hydrogels for drug delivery

Qiu, Y., & Park, K. (2001) · Advanced Drug Delivery Reviews · doi:10.1016/s0169-409x(01)00203-4 · Cited by 3,911

The Effect of Nanoparticle Size, Shape, and Surface Chemistry on Biological Systems

Albanese, A., Tang, P. S., & Chan, W. C. W. (2012) · Annual Review of Biomedical Engineering · doi:10.1146/annurev-bioeng-071811-150124 · Cited by 3,633

The EPR effect: Unique features of tumor blood vessels for drug delivery, factors involved, and limitations and augmentation of the effect

Fang, J., Nakamura, H., & Maeda, H. (2011) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2010.04.009 · Cited by 3,559

Impact of Nanotechnology on Drug Delivery

Farokhzad, O. C., & Langer, R. (2009) · ACS Nano · doi:10.1021/nn900002m · Cited by 3,348

Untitled work

(1989) · PubMed · Cited by 3,343

Thermo- and pH-responsive polymers in drug delivery☆

SCHMALJOHANN, D. (2006) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2006.09.020 · Cited by 3,023

Biomolecular coronas provide the biological identity of nanosized materials

Monopoli, M. P., Åberg, C., Salvati, A., & Dawson, K. A. (2012) · Nature Nanotechnology · doi:10.1038/nnano.2012.207 · Cited by 3,017

Therapeutic Nanoparticles for Drug Delivery in Cancer

Cho, K., Wang, X., Nie, S., Chen, Z. (., & Shin, D. M. (2008) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-07-1441 · Cited by 2,920

Nanoparticle-mediated cellular response is size-dependent

Jiang, W., Kim, B. Y. S., Rutka, J. T., & Chan, W. C. W. (2008) · Nature Nanotechnology · doi:10.1038/nnano.2008.30 · Cited by 2,776

Mesoporous silica nanoparticles as controlled release drug delivery and gene transfection carriers☆

SLOWING, I., VIVEROESCOTO, J., WU, C., & LIN, V (2008) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2008.03.012 · Cited by 2,653

100-GHz Transistors from Wafer-Scale Epitaxial Graphene

Lin, Y.-M., Dimitrakopoulos, C., Jenkins, K. A., Farmer, D. B., Chiu, H.-Y., Grill, A., & Avouris, P. (2010) · Science · doi:10.1126/science.1184289 · Cited by 2,514

The role of surface charge in cellular uptake and cytotoxicity of medical nanoparticles

Fröhlich, E. (2012) · International Journal of Nanomedicine · doi:10.2147/ijn.s36111 · Cited by 2,484

One-Step Assembly of Coordination Complexes for Versatile Film and Particle Engineering

Ejima, H., Richardson, J. J., Liang, K., Best, J. P., van Koeverden, M. P., Such, G. K., Cui, J., & Caruso, F. (2013) · Science · doi:10.1126/science.1237265 · Cited by 2,419

Plasmonic photothermal therapy (PPTT) using gold nanoparticles

Huang, X., Jain, P. K., El-Sayed, I. H., & El-Sayed, M. A. (2008) · Lasers in Medical Science · doi:10.1007/s10103-007-0470-x · Cited by 2,376

Rapid formation of plasma protein corona critically affects nanoparticle pathophysiology

Tenzer, S., Docter, D., Kuharev, J., Musyanovych, A., Fetz, V., Hecht, R., Schlenk, F., Fischer, D., Kiouptsi, K., Reinhardt, C., et al. (2013) · Nature Nanotechnology · doi:10.1038/nnano.2013.181 · Cited by 2,283

Gene Therapy of Human Severe Combined Immunodeficiency (SCID)-X1 Disease

Cavazzana-Calvo, M., Hacein-Bey, S., Basile, G. D. S., Gross, F., Yvon, E., Nusbaum, P., Selz, F., Hue, C., Certain, S., Casanova, J.-L., et al. (2000) · Science · doi:10.1126/science.288.5466.669 · Cited by 2,167

Ultrasmall Reduced Graphene Oxide with High Near-Infrared Absorbance for Photothermal Therapy

Robinson, J. T., Tabakman, S. M., Liang, Y., Wang, H., Sanchez Casalongue, H., Vinh, D., & Dai, H. (2011) · Journal of the American Chemical Society · doi:10.1021/ja2010175 · Cited by 2,099

Tumor delivery of macromolecular drugs based on the EPR effect

Torchilin, V. (2011) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2010.03.011 · Cited by 2,032

Nanomedicine: current status and future prospects

Moghimi, S. M., Hunter, A. C., & Murray, J. C. (2005) · The FASEB Journal · doi:10.1096/fj.04-2747rev · Cited by 2,029

Nanoparticles for photothermal therapies

Jaque, D., Martínez Maestro, L., del Rosal, B., Haro-Gonzalez, P., Benayas, A., Plaza, J. L., Martín Rodríguez, E., & García Solé, J. (2014) · Nanoscale · doi:10.1039/c4nr00708e · Cited by 1,936

Transferrin-functionalized nanoparticles lose their targeting capabilities when a biomolecule corona adsorbs on the surface

Salvati, A., Pitek, A. S., Monopoli, M. P., Prapainop, K., Bombelli, F. B., Hristov, D. R., Kelly, P. M., Åberg, C., Mahon, E., & Dawson, K. A. (2013) · Nature Nanotechnology · doi:10.1038/nnano.2012.237 · Cited by 1,912

Physical−Chemical Aspects of Protein Corona: Relevance to in Vitro and in Vivo Biological Impacts of Nanoparticles

Monopoli, M. P., Walczyk, D., Campbell, A., Elia, G., Lynch, I., Baldelli Bombelli, F., & Dawson, K. A. (2011) · Journal of the American Chemical Society · doi:10.1021/ja107583h · Cited by 1,835

Reduced cardiotoxicity and comparable efficacy in a phase IIItrial of pegylated liposomal doxorubicin HCl(CAELYX™/Doxil®) versus conventional doxorubicin forfirst-line treatment of metastatic breast cancer

O’Brien, M. E. R., Wigler, N., Inbar, M., Rosso, R., Grischke, E., Santoro, A., Catane, R., Kieback, D. G., Tomczak, P., Ackland, S. P., et al. (2004) · Annals of Oncology · doi:10.1093/annonc/mdh097 · Cited by 1,738

Design of polymeric nanoparticles for biomedical delivery applications

Elsabahy, M., & Wooley, K. L. (2012) · Chemical Society Reviews · doi:10.1039/c2cs15327k · Cited by 1,717

Multifunctional, stimuli-sensitive nanoparticulate systems for drug delivery

Torchilin, V. P. (2014) · Nature Reviews Drug Discovery · doi:10.1038/nrd4333 · Cited by 1,663

Germanene: a novel two-dimensional germanium allotrope akin to graphene and silicene

Dávila, M. E., Xian, L., Cahangirov, S., Rubio, A., & Le Lay, G. (2014) · New Journal of Physics · doi:10.1088/1367-2630/16/9/095002 · Cited by 1,601

Toxicity of nanomaterials

Sharifi, S., Behzadi, S., Laurent, S., Laird Forrest, M., Stroeve, P., & Mahmoudi, M. (2012) · Chem. Soc. Rev. · doi:10.1039/c1cs15188f · Cited by 1,460

Drug delivery strategy utilizing conjugation via reversible disulfide linkages: Role and site of cellular reducing activities

Saito, G., Swanson, J. A., & Lee, K.-D. (2003) · Advanced Drug Delivery Reviews · doi:10.1016/s0169-409x(02)00179-5 · Cited by 1,407

Thermo‐plasmonics: using metallic nanostructures as nano‐sources of heat

Baffou, G., & Quidant, R. (2013) · Laser & Photonics Reviews · doi:10.1002/lpor.201200003 · Cited by 1,392

Glutathione-responsive nano-vehicles as a promising platform for targeted intracellular drug and gene delivery

Cheng, R., Feng, F., Meng, F., Deng, C., Feijen, J., & Zhong, Z. (2011) · Journal of Controlled Release · doi:10.1016/j.jconrel.2011.01.030 · Cited by 1,360

Dual and multi-stimuli responsive polymeric nanoparticles for programmed site-specific drug delivery

Cheng, R., Meng, F., Deng, C., Klok, H.-A., & Zhong, Z. (2013) · Biomaterials · doi:10.1016/j.biomaterials.2013.01.084 · Cited by 1,354

Small-scale systems for in vivo drug delivery

LaVan, D. A., McGuire, T., & Langer, R. (2003) · Nature Biotechnology · doi:10.1038/nbt876 · Cited by 1,304

In situ-forming hydrogels--review of temperature-sensitive systems

Ruel-Gariépy, E., & Leroux, J.-C. (2004) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/j.ejpb.2004.03.019 · Cited by 1,297

Mesoporous silica nanoparticles in drug delivery and biomedical applications

Wang, Y., Zhao, Q., Han, N., Bai, L., Li, J., Liu, J., Che, E., Hu, L., Zhang, Q., Jiang, T., et al. (2015) · Nanomedicine: Nanotechnology, Biology and Medicine · doi:10.1016/j.nano.2014.09.014 · Cited by 1,192

Cellular Uptake, Intracellular Trafficking, and Cytotoxicity of Nanomaterials

Zhao, F., Zhao, Y., Liu, Y., Chang, X., Chen, C., & Zhao, Y. (2011) · Small · doi:10.1002/smll.201100001 · Cited by 1,175

Tailor-Made Dual pH-Sensitive Polymer–Doxorubicin Nanoparticles for Efficient Anticancer Drug Delivery

Du, J.-Z., Du, X.-J., Mao, C.-Q., & Wang, J. (2011) · Journal of the American Chemical Society · doi:10.1021/ja207150n · Cited by 1,172

Gold nanorod assisted near-infrared plasmonic photothermal therapy (PPTT) of squamous cell carcinoma in mice

Dickerson, E. B., Dreaden, E. C., Huang, X., El-Sayed, I. H., Chu, H., Pushpanketh, S., McDonald, J. F., & El-Sayed, M. A. (2008) · Cancer Letters · doi:10.1016/j.canlet.2008.04.026 · Cited by 1,172

Proteases: Multifunctional Enzymes in Life and Disease

López-Otín, C., & Bond, J. S. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.r800035200 · Cited by 1,144

Antimicrobial strategies centered around reactive oxygen species – bactericidal antibiotics, photodynamic therapy, and beyond

Vatansever, F., de Melo, W. C. M. A., Avci, P., Vecchio, D., Sadasivam, M., Gupta, A., Chandran, R., Karimi, M., Parizotto, N. A., Yin, R., et al. (2013) · FEMS Microbiology Reviews · doi:10.1111/1574-6976.12026 · Cited by 1,127

pH-Sensitive nano-systems for drug delivery in cancer therapy

Liu, J., Huang, Y., Kumar, A., Tan, A., Jin, S., Mozhi, A., & Liang, X.-J. (2014) · Biotechnology Advances · doi:10.1016/j.biotechadv.2013.11.009 · Cited by 1,121

The big picture on nanomedicine: the state of investigational and approved nanomedicine products

Etheridge, M. L., Campbell, S. A., Erdman, A. G., Haynes, C. L., Wolf, S. M., & McCullough, J. (2013) · Nanomedicine: Nanotechnology, Biology and Medicine · doi:10.1016/j.nano.2012.05.013 · Cited by 1,088

Biocompatibility, Biodistribution, and Drug‐Delivery Efficiency of Mesoporous Silica Nanoparticles for Cancer Therapy in Animals

Lu, J., Liong, M., Li, Z., Zink, J. I., & Tamanoi, F. (2010) · Small · doi:10.1002/smll.201000538 · Cited by 1,074

Size-dependent cytotoxicity of silver nanoparticles in human lung cells: the role of cellular uptake, agglomeration and Ag release

Gliga, A. R., Skoglund, S., Odnevall Wallinder, I., Fadeel, B., & Karlsson, H. L. (2014) · Particle and Fibre Toxicology · doi:10.1186/1743-8977-11-11 · Cited by 1,074

Temperature- and light-responsive smart polymer materials

Jochum, F. D., & Theato, P. (2013) · Chem. Soc. Rev. · doi:10.1039/c2cs35191a · Cited by 1,062

Sustained Correction of X-Linked Severe Combined Immunodeficiency by ex Vivo Gene Therapy

Hacein-Bey-Abina, S., Le Deist, F., Carlier, F., Bouneaud, C., Hue, C., De Villartay, J.-P., Thrasher, A. J., Wulffraat, N., Sorensen, R., Dupuis-Girod, S., et al. (2002) · New England Journal of Medicine · doi:10.1056/nejmoa012616 · Cited by 1,058

Magnetic nanoparticles for theragnostics

Shubayev, V. I., Pisanic, T. R., & Jin, S. (2009) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2009.03.007 · Cited by 1,028

The effect of particle size on the cytotoxicity, inflammation, developmental toxicity and genotoxicity of silver nanoparticles

Park, M. V. D. Z., Neigh, A. M., Vermeulen, J. P., de la Fonteyne, L. J. J., Verharen, H. W., Briedé, J. J., van Loveren, H., & de Jong, W. H. (2011) · Biomaterials · doi:10.1016/j.biomaterials.2011.08.085 · Cited by 1,004

The effect of the shape of mesoporous silica nanoparticles on cellular uptake and cell function

Huang, X., Teng, X., Chen, D., Tang, F., & He, J. (2010) · Biomaterials · doi:10.1016/j.biomaterials.2009.09.060 · Cited by 1,002

Binding of blood proteins to carbon nanotubes reduces cytotoxicity

Ge, C., Du, J., Zhao, L., Wang, L., Liu, Y., Li, D., Yang, Y., Zhou, R., Zhao, Y., Chai, Z., et al. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1105270108 · Cited by 940

Cell-specific targeting of nanoparticles by multivalent attachment of small molecules

Weissleder, R., Kelly, K., Sun, E. Y., Shtatland, T., & Josephson, L. (2005) · Nature Biotechnology · doi:10.1038/nbt1159 · Cited by 904

The relevance of tumour pH to the treatment of malignant disease

Wike-Hooley, J. L., Haveman, J., & Reinhold, H. S. (1984) · Radiotherapy and Oncology · doi:10.1016/s0167-8140(84)80077-8 · Cited by 903

Protein Corona-Mediated Mitigation of Cytotoxicity of Graphene Oxide

Hu, W., Peng, C., Lv, M., Li, X., Zhang, Y., Chen, N., Fan, C., & Huang, Q. (2011) · ACS Nano · doi:10.1021/nn200021j · Cited by 895

Toxicology of nanoparticles

Elsaesser, A., & Howard, C. V. (2012) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2011.09.001 · Cited by 895

Nanoparticle-induced unfolding of fibrinogen promotes Mac-1 receptor activation and inflammation

Deng, Z. J., Liang, M., Monteiro, M., Toth, I., & Minchin, R. F. (2011) · Nature Nanotechnology · doi:10.1038/nnano.2010.250 · Cited by 893

Environment-sensitive hydrogels for drug delivery

Qiu, Y., & Park, K. (2012) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2012.09.024 · Cited by 875

Microbubbles in medical imaging: current applications and future directions

Lindner, J. R. (2004) · Nature Reviews Drug Discovery · doi:10.1038/nrd1417 · Cited by 872

Nanoparticle Adhesion to the Cell Membrane and Its Effect on Nanoparticle Uptake Efficiency

Lesniak, A., Salvati, A., Santos-Martinez, M. J., Radomski, M. W., Dawson, K. A., & Åberg, C. (2013) · Journal of the American Chemical Society · doi:10.1021/ja309812z · Cited by 852

The 'right' size in nanobiotechnology

Whitesides, G. M. (2003) · Nature Biotechnology · doi:10.1038/nbt872 · Cited by 843

Understanding ultrasound induced sonoporation: Definitions and underlying mechanisms

Lentacker, I., De Cock, I., Deckers, R., De Smedt, S. C., & Moonen, C. T. W. (2014) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2013.11.008 · Cited by 815

Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles

Walkey, C. D., Olsen, J. B., Song, F., Liu, R., Guo, H., Olsen, D. W. H., Cohen, Y., Emili, A., & Chan, W. C. W. (2014) · ACS Nano · doi:10.1021/nn406018q · Cited by 815

Plasmonics for near-field nano-imaging and superlensing

Kawata, S., Inouye, Y., & Verma, P. (2009) · Nature Photonics · doi:10.1038/nphoton.2009.111 · Cited by 807

Sub-10 nm Hexagonal Lanthanide-Doped NaLuF4 Upconversion Nanocrystals for Sensitive Bioimaging in Vivo

Liu, Q., Sun, Y., Yang, T., Feng, W., Li, C., & Li, F. (2011) · Journal of the American Chemical Society · doi:10.1021/ja207078s · Cited by 798

Enzyme-responsive nanoparticles for drug release and diagnostics

de la Rica, R., Aili, D., & Stevens, M. M. (2012) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2012.01.002 · Cited by 765

Size-dependent genotoxicity of graphene nanoplatelets in human stem cells

Akhavan, O., Ghaderi, E., & Akhavan, A. (2012) · Biomaterials · doi:10.1016/j.biomaterials.2012.07.040 · Cited by 756

The Evolution of the Protein Corona around Nanoparticles: A Test Study

Lundqvist, M., Stigler, J., Cedervall, T., Berggård, T., Flanagan, M. B., Lynch, I., Elia, G., & Dawson, K. (2011) · ACS Nano · doi:10.1021/nn202458g · Cited by 752

Biomolecule-sensitive hydrogels

Miyata, T., Uragami, T., & Nakamae, K. (2002) · Advanced Drug Delivery Reviews · doi:10.1016/s0169-409x(01)00241-1 · Cited by 735

Enzyme-responsive polymeric assemblies, nanoparticles and hydrogels

Hu, J., Zhang, G., & Liu, S. (2012) · Chemical Society Reviews · doi:10.1039/c2cs35103j · Cited by 722

The cytotoxicity of cadmium-based quantum dots

Chen, N., He, Y., Su, Y., Li, X., Huang, Q., Wang, H., Zhang, X., Tai, R., & Fan, C. (2012) · Biomaterials · doi:10.1016/j.biomaterials.2011.10.070 · Cited by 717

Graphene: Promises, Facts, Opportunities, and Challenges in Nanomedicine

Mao, H. Y., Laurent, S., Chen, W., Akhavan, O., Imani, M., Ashkarran, A. A., & Mahmoudi, M. (2013) · Chemical Reviews · doi:10.1021/cr300335p · Cited by 701

Nanocomposite polymer hydrogels

Schexnailder, P., & Schmidt, G. (2009) · Colloid and Polymer Science · doi:10.1007/s00396-008-1949-0 · Cited by 697

Inductive heating of ferrimagnetic particles and magnetic fluids: Physical evaluation of their potential for hyperthermia

Jordan, A., Wust, P., Fählin, H., John, W., Hinz, A., & Felix, R. (1993) · International Journal of Hyperthermia · doi:10.3109/02656739309061478 · Cited by 694

pH-Responsive polymers: synthesis, properties and applications

Dai, S., Ravi, P., & Tam, K. C. (2008) · Soft Matter · doi:10.1039/b714741d · Cited by 693

Organically Modified Silica Nanoparticles Co-encapsulating Photosensitizing Drug and Aggregation-Enhanced Two-Photon Absorbing Fluorescent Dye Aggregates for Two-Photon Photodynamic Therapy

Kim, S., Ohulchanskyy, T. Y., Pudavar, H. E., Pandey, R. K., & Prasad, P. N. (2007) · Journal of the American Chemical Society · doi:10.1021/ja0680257 · Cited by 689

Chemical Basis of Interactions Between Engineered Nanoparticles and Biological Systems

Mu, Q., Jiang, G., Chen, L., Zhou, H., Fourches, D., Tropsha, A., & Yan, B. (2014) · Chemical Reviews · doi:10.1021/cr400295a · Cited by 679

Control of protein–ligand recognition using a stimuli-responsive polymer

Stayton, P. S., Shimoboji, T., Long, C., Chilkoti, A., Ghen, G., Harris, J. M., & Hoffman, A. S. (1995) · Nature · doi:10.1038/378472a0 · Cited by 677

Photosensitizer-Loaded Gold Vesicles with Strong Plasmonic Coupling Effect for Imaging-Guided Photothermal/Photodynamic Therapy

Lin, J., Wang, S., Huang, P., Wang, Z., Chen, S., Niu, G., Li, W., He, J., Cui, D., Lu, G., et al. (2013) · ACS Nano · doi:10.1021/nn4011686 · Cited by 661

Efficacy of Gene Therapy for X-Linked Severe Combined Immunodeficiency

Hacein-Bey-Abina, S., Hauer, J., Lim, A., Picard, C., Wang, G. P., Berry, C. C., Martinache, C., Rieux-Laucat, F., Latour, S., Belohradsky, B. H., et al. (2010) · New England Journal of Medicine · doi:10.1056/nejmoa1000164 · Cited by 639

Magnetic responsive polymer composite materials

Thévenot, J., Oliveira, H., Sandre, O., & Lecommandoux, S. (2013) · Chemical Society Reviews · doi:10.1039/c3cs60058k · Cited by 633

Nanocomposites of TiO2 and Reduced Graphene Oxide as Efficient Photocatalysts for Hydrogen Evolution

Fan, W., Lai, Q., Zhang, Q., & Wang, Y. (2011) · The Journal of Physical Chemistry C · doi:10.1021/jp2008804 · Cited by 632

Redox compartmentalization in eukaryotic cells

Go, Y.-M., & Jones, D. P. (2008) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2008.01.011 · Cited by 626

Mechanisms of genotoxicity. A review of in vitro and in vivo studies with engineered nanoparticles

Magdolenova, Z., Collins, A., Kumar, A., Dhawan, A., Stone, V., & Dusinska, M. (2014) · Nanotoxicology · doi:10.3109/17435390.2013.773464 · Cited by 616

Stability of Citrate, PVP, and PEG Coated Silver Nanoparticles in Ecotoxicology Media

Tejamaya, M., Römer, I., Merrifield, R. C., & Lead, J. R. (2012) · Environmental Science & Technology · doi:10.1021/es2038596 · Cited by 608

pH-Triggered Controlled Drug Release from Mesoporous Silica Nanoparticles via Intracelluar Dissolution of ZnO Nanolids

Muhammad, F., Guo, M., Qi, W., Sun, F., Wang, A., Guo, Y., & Zhu, G. (2011) · Journal of the American Chemical Society · doi:10.1021/ja200328s · Cited by 603

Differential Uptake of Functionalized Polystyrene Nanoparticles by Human Macrophages and a Monocytic Cell Line

Lunov, O., Syrovets, T., Loos, C., Beil, J., Delacher, M., Tron, K., Nienhaus, G. U., Musyanovych, A., Mailänder, V., Landfester, K., et al. (2011) · ACS Nano · doi:10.1021/nn2000756 · Cited by 600

Autonomous in Vitro Anticancer Drug Release from Mesoporous Silica Nanoparticles by pH-Sensitive Nanovalves

Meng, H., Xue, M., Xia, T., Zhao, Y.-L., Tamanoi, F., Stoddart, J. F., Zink, J. I., & Nel, A. E. (2010) · Journal of the American Chemical Society · doi:10.1021/ja104501a · Cited by 595

Therapeutic applications of lipid-coated microbubbles

Unger, E. C., Porter, T., Culp, W., Labell, R., Matsunaga, T., & Zutshi, R. (2004) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2003.12.006 · Cited by 591

Polymer-Coated Nanoparticles Interacting with Proteins and Cells: Focusing on the Sign of the Net Charge

Hühn, D., Kantner, K., Geidel, C., Brandholt, S., De Cock, I., Soenen, S. J. H., Rivera_Gil, P., Montenegro, J.-M., Braeckmans, K., Müllen, K., et al. (2013) · ACS Nano · doi:10.1021/nn3059295 · Cited by 580

Enzyme-Responsive Snap-Top Covered Silica Nanocontainers

Patel, K., Angelos, S., Dichtel, W. R., Coskun, A., Yang, Y.-W., Zink, J. I., & Stoddart, J. F. (2008) · Journal of the American Chemical Society · doi:10.1021/ja0772086 · Cited by 576

Self-Cross-Linked Polymer Nanogels: A Versatile Nanoscopic Drug Delivery Platform

Ryu, J.-H., Chacko, R. T., Jiwpanich, S., Bickerton, S., Babu, R. P., & Thayumanavan, S. (2010) · Journal of the American Chemical Society · doi:10.1021/ja1069932 · Cited by 553

Controlled and targeted tumor chemotherapy by ultrasound-activated nanoemulsions/microbubbles

Rapoport, N. Y., Kennedy, A. M., Shea, J. E., Scaife, C. L., & Nam, K.-H. (2009) · Journal of Controlled Release · doi:10.1016/j.jconrel.2009.05.026 · Cited by 551

Stimuli-Responsive Supramolecular Assemblies of Linear-Dendritic Copolymers

Gillies, E. R., Jonsson, T. B., & Fréchet, J. M. J. (2004) · Journal of the American Chemical Society · doi:10.1021/ja0463738 · Cited by 549

Nano-microparticles as immune adjuvants: correlating particle sizes and the resultant immune responses

Oyewumi, M. O., Kumar, A., & Cui, Z. (2010) · Expert Review of Vaccines · doi:10.1586/erv.10.89 · Cited by 547

Multi-functionalized graphene oxide based anticancer drug-carrier with dual-targeting function and pH-sensitivity

Yang, X., Wang, Y., Huang, X., Ma, Y., Huang, Y., Yang, R., Duan, H., & Chen, Y. (2011) · J. Mater. Chem. · doi:10.1039/c0jm02494e · Cited by 547

Shear-Activated Nanotherapeutics for Drug Targeting to Obstructed Blood Vessels

Korin, N., Kanapathipillai, M., Matthews, B. D., Crescente, M., Brill, A., Mammoto, T., Ghosh, K., Jurek, S., Bencherif, S. A., Bhatta, D., et al. (2012) · Science · doi:10.1126/science.1217815 · Cited by 540

o-Nitrobenzyl Alcohol Derivatives: Opportunities in Polymer and Materials Science

Zhao, H., Sterner, E. S., Coughlin, E. B., & Theato, P. (2012) · Macromolecules · doi:10.1021/ma201924h · Cited by 539

Nanotoxicology and in vitro studies: The need of the hour

Arora, S., Rajwade, J. M., & Paknikar, K. M. (2012) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2011.11.010 · Cited by 537

Drug Release from Electric-Field-Responsive Nanoparticles

Ge, J., Neofytou, E., Cahill, T. J., Beygui, R. E., & Zare, R. N. (2012) · ACS Nano · doi:10.1021/nn203430m · Cited by 534

Redox activation of metal-based prodrugs as a strategy for drug delivery

Graf, N., & Lippard, S. J. (2012) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2012.01.007 · Cited by 523

Fundamentals and Applications of Controlled Release Drug Delivery

(2012) · Springer eBooks · doi:10.1007/978-1-4614-0881-9 · Cited by 521

Light‐sensitive Intelligent Drug Delivery Systems†

Alvarez‐Lorenzo, C., Bromberg, L., & Concheiro, A. (2009) · Photochemistry and Photobiology · doi:10.1111/j.1751-1097.2008.00530.x · Cited by 519

(Intra)Cellular Stability of Inorganic Nanoparticles: Effects on Cytotoxicity, Particle Functionality, and Biomedical Applications

Soenen, S. J., Parak, W. J., Rejman, J., & Manshian, B. (2015) · Chemical Reviews · doi:10.1021/cr400714j · Cited by 515

Toward Single-DNA Electrochemical Biosensing by Graphene Nanowalls

Akhavan, O., Ghaderi, E., & Rahighi, R. (2012) · ACS Nano · doi:10.1021/nn300261t · Cited by 514

Use of Size and a Copolymer Design Feature To Improve the Biodistribution and the Enhanced Permeability and Retention Effect of Doxorubicin-Loaded Mesoporous Silica Nanoparticles in a Murine Xenograft Tumor Model

Meng, H., Xue, M., Xia, T., Ji, Z., Tarn, D. Y., Zink, J. I., & Nel, A. E. (2011) · ACS Nano · doi:10.1021/nn200809t · Cited by 509

Multicompartmentalized polymeric systems: towards biomimetic cellular structure and function

Marguet, M., Bonduelle, C., & Lecommandoux, S. (2013) · Chem. Soc. Rev. · doi:10.1039/c2cs35312a · Cited by 505

Reversible versus Irreversible Binding of Transferrin to Polystyrene Nanoparticles: Soft and Hard Corona

Milani, S., Baldelli Bombelli, F., Pitek, A. S., Dawson, K. A., & Rädler, J. (2012) · ACS Nano · doi:10.1021/nn204951s · Cited by 496

Doxorubicin Loaded Magnetic Polymersomes: Theranostic Nanocarriers for MR Imaging and Magneto-Chemotherapy

Sanson, C., Diou, O., Thévenot, J., Ibarboure, E., Soum, A., Brûlet, A., Miraux, S., Thiaudière, E., Tan, S., Brisson, A., et al. (2011) · ACS Nano · doi:10.1021/nn102762f · Cited by 489

State-of-the-art materials for ultrasound-triggered drug delivery

Sirsi, S. R., & Borden, M. A. (2014) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2013.12.010 · Cited by 488

Size‐dependent cellular toxicity of silver nanoparticles

Kim, T., Kim, M., Park, H., Shin, U. S., Gong, M., & Kim, H. (2012) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.34053 · Cited by 483

Redox-sensitive micelles self-assembled from amphiphilic hyaluronic acid-deoxycholic acid conjugates for targeted intracellular delivery of paclitaxel

Li, J., Huo, M., Wang, J., Zhou, J., Mohammad, J. M., Zhang, Y., Zhu, Q., Waddad, A. Y., & Zhang, Q. (2012) · Biomaterials · doi:10.1016/j.biomaterials.2011.11.022 · Cited by 468

Micelles and nanoparticles for ultrasonic drug and gene delivery

Husseini, G. A., & Pitt, W. G. (2008) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2008.03.008 · Cited by 468

Chitosan, hyaluronan and chondroitin sulfate in tissue engineering for cartilage regeneration: A review

Muzzarelli, R. A. A., Greco, F., Busilacchi, A., Sollazzo, V., & Gigante, A. (2012) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2012.04.057 · Cited by 457

Near-Infrared Light-Triggered Dissociation of Block Copolymer Micelles Using Upconverting Nanoparticles

Yan, B., Boyer, J.-C., Branda, N. R., & Zhao, Y. (2011) · Journal of the American Chemical Society · doi:10.1021/ja209793b · Cited by 455

Recent advances in chitosan-based nanoparticles for oral delivery of macromolecules

Chen, M.-C., Mi, F.-L., Liao, Z.-X., Hsiao, C.-W., Sonaje, K., Chung, M.-F., Hsu, L.-W., & Sung, H.-W. (2013) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2012.10.010 · Cited by 451

Echocardiographic Destruction of Albumin Microbubbles Directs Gene Delivery to the Myocardium

Shohet, R. V., Chen, S., Zhou, Y.-T., Wang, Z., Meidell, R. S., Unger, R. H., & Grayburn, P. A. (2000) · Circulation · doi:10.1161/01.cir.101.22.2554 · Cited by 446

Ultrasound-mediated blood–brain barrier disruption for targeted drug delivery in the central nervous system

Aryal, M., Arvanitis, C. D., Alexander, P. M., & McDannold, N. (2014) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2014.01.008 · Cited by 443

Glucose-Responsive Microgels Integrated with Enzyme Nanocapsules for Closed-Loop Insulin Delivery

Gu, Z., Dang, T. T., Ma, M., Tang, B. C., Cheng, H., Jiang, S., Dong, Y., Zhang, Y., & Anderson, D. G. (2013) · ACS Nano · doi:10.1021/nn401617u · Cited by 428

“Smart” nanoparticles: Preparation, characterization and applications

Ballauff, M., & Lu, Y. (2007) · Polymer · doi:10.1016/j.polymer.2007.02.004 · Cited by 425

Photochemical internalization: a novel technology for delivery of macromolecules into cytosol.

Berg, K., Selbo, P. K., Prasmickaite, L., Tjelle, T. E., Sandvig, K., Moan, J. E., Gaudernack, G., Fodstad, Ø., Kjølsrud, S., Anholt, H., et al. (1999) · PubMed · Cited by 423

Electrically Controlled Drug Delivery from Graphene Oxide Nanocomposite Films

Weaver, C. L., LaRosa, J. M., Luo, X., & Cui, X. T. (2014) · ACS Nano · doi:10.1021/nn406223e · Cited by 421

Photothermally Triggered Cytosolic Drug Delivery via Endosome Disruption Using a Functionalized Reduced Graphene Oxide

Kim, H., Lee, D., Kim, J., Kim, T.-I., & Kim, W. J. (2013) · ACS Nano · doi:10.1021/nn403096s · Cited by 420

Impact of Protein Modification on the Protein Corona on Nanoparticles and Nanoparticle–Cell Interactions

Treuel, L., Brandholt, S., Maffre, P., Wiegele, S., Shang, L., & Nienhaus, G. U. (2014) · ACS Nano · doi:10.1021/nn405019v · Cited by 419

Stimuli-responsive nanomaterials for therapeutic protein delivery

Lu, Y., Sun, W., & Gu, Z. (2014) · Journal of Controlled Release · doi:10.1016/j.jconrel.2014.08.015 · Cited by 415

Smart drug delivery systems: from fundamentals to the clinic

Alvarez-Lorenzo, C., & Concheiro, A. (2014) · Chem. Commun. · doi:10.1039/c4cc01429d · Cited by 415

Lectin-mediated drug targeting: history and applications

Bies, C., Lehr, C.-M., & Woodley, J. F. (2004) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2003.10.030 · Cited by 414

Organic-coated silver nanoparticles in biological and environmental conditions: Fate, stability and toxicity

Sharma, V. K., Siskova, K. M., Zboril, R., & Gardea-Torresdey, J. L. (2014) · Advances in Colloid and Interface Science · doi:10.1016/j.cis.2013.12.002 · Cited by 413

Smart Drug Delivery through DNA/Magnetic Nanoparticle Gates

Ruiz-Hernández, E., Baeza, A., & Vallet-Regí, M. (2011) · ACS Nano · doi:10.1021/nn1029229 · Cited by 408

Ecotoxicity of nanosized TiO2. Review of in vivo data

Menard, A., Drobne, D., & Jemec, A. (2011) · Environmental Pollution · doi:10.1016/j.envpol.2010.11.027 · Cited by 403

Disulfide-cross-linked PEG-poly(amino acid)s copolymer micelles for glutathione-mediated intracellular drug delivery

Koo, A. N., Lee, H. J., Kim, S. E., Chang, J. H., Park, C., Kim, C., Park, J. H., & Lee, S. C. (2008) · Chemical Communications · doi:10.1039/b815918a · Cited by 395

Protein corona significantly reduces active targeting yield

Mirshafiee, V., Mahmoudi, M., Lou, K., Cheng, J., & Kraft, M. L. (2013) · Chemical Communications · doi:10.1039/c3cc37307j · Cited by 380

Ambient fine particulate air pollution triggers ST-elevation myocardial infarction, but not non-ST elevation myocardial infarction: a case-crossover study

Gardner, B., Ling, F., Hopke, P. K., Frampton, M. W., Utell, M. J., Zareba, W., Cameron, S. J., Chalupa, D., Kane, C., Kulandhaisamy, S., et al. (2014) · Particle and Fibre Toxicology · doi:10.1186/1743-8977-11-1 · Cited by 379

Designed Synthesis of CeO2 Nanorods and Nanowires for Studying Toxicological Effects of High Aspect Ratio Nanomaterials

Ji, Z., Wang, X., Zhang, H., Lin, S., Meng, H., Sun, B., George, S., Xia, T., Nel, A. E., & Zink, J. I. (2012) · ACS Nano · doi:10.1021/nn3012114 · Cited by 378

Redox-optimized ROS balance: A unifying hypothesis

Aon, M. A., Cortassa, S., & O'Rourke, B. (2010) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/j.bbabio.2010.02.016 · Cited by 378

Sonoporation: mechanical DNA delivery by ultrasonic cavitation.

Miller, D. L., Pislaru, S. V., & Greenleaf, J. F. (2002) · Somatic Cell and Molecular Genetics · doi:10.1023/a:1022983907223 · Cited by 373

Poly(ortho esters): synthesis, characterization, properties and uses

Heller, J., Barr, J., Ng, S. Y., Abdellauoi, K. S., & Gurny, R. (2002) · Advanced Drug Delivery Reviews · doi:10.1016/s0169-409x(02)00055-8 · Cited by 371

Controlled Cell Adhesion on PEG‐Based Switchable Surfaces

Wischerhoff, E., Uhlig, K., Lankenau, A., Börner, H. G., Laschewsky, A., Duschl, C., & Lutz, J. (2008) · Angewandte Chemie International Edition · doi:10.1002/anie.200801202 · Cited by 366

Hyperthermia-triggered drug delivery from temperature-sensitive liposomes using MRI-guided high intensity focused ultrasound

Grüll, H., & Langereis, S. (2012) · Journal of Controlled Release · doi:10.1016/j.jconrel.2012.04.041 · Cited by 360

Health and Ecosystem Risks of Graphene

Hu, X., & Zhou, Q. (2013) · Chemical Reviews · doi:10.1021/cr300045n · Cited by 360

Glutathione‐Induced Intracellular Release of Guests from Mesoporous Silica Nanocontainers with Cyclodextrin Gatekeepers

Kim, H., Kim, S., Park, C., Lee, H., Park, H. J., & Kim, C. (2010) · Advanced Materials · doi:10.1002/adma.201001417 · Cited by 356

pH-sensitive poly (histidine)-PEG/DSPE-PEG co-polymer micelles for cytosolic drug delivery

Wu, H., Zhu, L., & Torchilin, V. P. (2013) · Biomaterials · doi:10.1016/j.biomaterials.2012.08.072 · Cited by 355

Post-mortem studies in glioblastoma patients treated with thermotherapy using magnetic nanoparticles

van Landeghem, F. K. H., Maier-Hauff, K., Jordan, A., Hoffmann, K.-T., Gneveckow, U., Scholz, R., Thiesen, B., Brück, W., & von Deimling, A. (2009) · Biomaterials · doi:10.1016/j.biomaterials.2008.09.044 · Cited by 355

Heat Conduction across Monolayer and Few-Layer Graphenes

Koh, Y. K., Bae, M.-H., Cahill, D. G., & Pop, E. (2010) · Nano Letters · doi:10.1021/nl101790k · Cited by 355

Facile, scalable synthesis of edge-halogenated graphene nanoplatelets as efficient metal-free eletrocatalysts for oxygen reduction reaction

Jeon, I.-Y., Choi, H.-J., Choi, M., Seo, J.-M., Jung, S.-M., Kim, M.-J., Zhang, S., Zhang, L., Xia, Z., Dai, L., et al. (2013) · Scientific Reports · doi:10.1038/srep01810 · Cited by 353

Effect of Nanoparticles on the Cell Life Cycle

Mahmoudi, M., Azadmanesh, K., Shokrgozar, M. A., Journeay, W. S., & Laurent, S. (2011) · Chemical Reviews · doi:10.1021/cr1003166 · Cited by 352

Shape-Changing and Amphiphilicity-Reversing Janus Particles with pH-Responsive Surfactant Properties

Tu, F., & Lee, D. (2014) · Journal of the American Chemical Society · doi:10.1021/ja503189r · Cited by 352

Current Progress in Reactive Oxygen Species (ROS)‐Responsive Materials for Biomedical Applications

Lee, S. H., Gupta, M. K., Bang, J. B., Bae, H., & Sung, H. (2013) · Advanced Healthcare Materials · doi:10.1002/adhm.201200423 · Cited by 351

Microbubble-enhanced ultrasound for vascular gene delivery

Lawrie, A., Brisken, A., Francis, S., Cumberland, D., Crossman, D., & Newman, C. (2000) · Gene Therapy · doi:10.1038/sj.gt.3301339 · Cited by 343

Polymer Micelles Stabilization on Demand through Reversible Photo-Cross-Linking

Jiang, J., Qi, B., Lepage, M., & Zhao, Y. (2007) · Macromolecules · doi:10.1021/ma062493j · Cited by 339

Biodegradable stimuli-responsive polypeptide materials prepared by ring opening polymerization

Shen, Y., Fu, X., Fu, W., & Li, Z. (2015) · Chemical Society Reviews · doi:10.1039/c4cs00271g · Cited by 339

A thermosensitive hydrogel based on quaternized chitosan and poly(ethylene glycol) for nasal drug delivery system

Wu, J., Wei, W., Wang, L.-Y., Su, Z.-G., & Ma, G.-H. (2007) · Biomaterials · doi:10.1016/j.biomaterials.2006.12.024 · Cited by 336

Effects of various physicochemical characteristics on the toxicities of ZnO and TiO2 nanoparticles toward human lung epithelial cells

Hsiao, I.-L., & Huang, Y.-J. (2011) · Science of The Total Environment · doi:10.1016/j.scitotenv.2010.12.033 · Cited by 335

Magnetic resonance imaging of high intensity focused ultrasound mediated drug delivery from temperature-sensitive liposomes: An in vivo proof-of-concept study

de Smet, M., Heijman, E., Langereis, S., Hijnen, N. M., & Grüll, H. (2011) · Journal of Controlled Release · doi:10.1016/j.jconrel.2010.10.036 · Cited by 330

Quantum Dot Cytotoxicity and Ways To Reduce It

Winnik, F. M., & Maysinger, D. (2013) · Accounts of Chemical Research · doi:10.1021/ar3000585 · Cited by 330

In situ gelling pH- and temperature-sensitive biodegradable block copolymer hydrogels for drug delivery

Singh, N. K., & Lee, D. S. (2014) · Journal of Controlled Release · doi:10.1016/j.jconrel.2014.04.056 · Cited by 326

Differential Roles of the Protein Corona in the Cellular Uptake of Nanoporous Polymer Particles by Monocyte and Macrophage Cell Lines

Yan, Y., Gause, K. T., Kamphuis, M. M. J., Ang, C.-S., O’Brien-Simpson, N. M., Lenzo, J. C., Reynolds, E. C., Nice, E. C., & Caruso, F. (2013) · ACS Nano · doi:10.1021/nn404481f · Cited by 322

Temperature-Responsive Interpenetrating Polymer Networks Constructed with Poly(acrylic acid) and Poly(N,N-dimethylacrylamide)

Aoki, T., Kawashima, M., Katono, H., Sanui, K., Ogata, N., Okano, T., & Sakurai, Y. (1994) · Macromolecules · doi:10.1021/ma00082a010 · Cited by 314

Well-defined, reversible disulfide cross-linked micelles for on-demand paclitaxel delivery

Li, Y., Xiao, K., Luo, J., Xiao, W., Lee, J. S., Gonik, A. M., Kato, J., Dong, T. A., & Lam, K. S. (2011) · Biomaterials · doi:10.1016/j.biomaterials.2011.05.050 · Cited by 312

Enzyme-Responsive Intracellular Controlled Release Using Nanometric Silica Mesoporous Supports Capped with “Saccharides”

Bernardos, A., Mondragón, L., Aznar, E., Marcos, M. D., Martínez-Máñez, R., Sancenón, F., Soto, J., Barat, J. M., Pérez-Payá, E., Guillem, C., et al. (2010) · ACS Nano · doi:10.1021/nn101499d · Cited by 310

A New Two‐Photon‐Sensitive Block Copolymer Nanocarrier

Babin, J., Pelletier, M., Lepage, M., Allard, J., Morris, D., & Zhao, Y. (2009) · Angewandte Chemie International Edition · doi:10.1002/anie.200900255 · Cited by 305

Advances in self-assembled chitosan nanomaterials for drug delivery

Yang, Y., Wang, S., Wang, Y., Wang, X., Wang, Q., & Chen, M. (2014) · Biotechnology Advances · doi:10.1016/j.biotechadv.2014.07.007 · Cited by 301

Bacteria‐Responsive Multifunctional Nanogel for Targeted Antibiotic Delivery

Xiong, M., Li, Y., Bao, Y., Yang, X., Hu, B., & Wang, J. (2012) · Advanced Materials · doi:10.1002/adma.201202847 · Cited by 299

Cytotoxicity of hydroxyapatite nanoparticles is shape and cell dependent

Zhao, X., Ng, S., Heng, B. C., Guo, J., Ma, L., Tan, T. T. Y., Ng, K. W., & Loo, S. C. J. (2013) · Archives of Toxicology · doi:10.1007/s00204-012-0827-1 · Cited by 299

Stimuli-responsive copolymer solution and surface assemblies for biomedical applications

Kelley, E. G., Albert, J. N. L., Sullivan, M. O., & Epps, III (2013) · Chemical Society Reviews · doi:10.1039/c3cs35512h · Cited by 295

Ultrasound mediated transdermal drug delivery

Azagury, A., Khoury, L., Enden, G., & Kost, J. (2014) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2014.01.007 · Cited by 294

Shear-stress sensitive lenticular vesicles for targeted drug delivery

Holme, M. N., Fedotenko, I. A., Abegg, D., Althaus, J., Babel, L., Favarger, F., Reiter, R., Tanasescu, R., Zaffalon, P.-L., Ziegler, A., et al. (2012) · Nature Nanotechnology · doi:10.1038/nnano.2012.84 · Cited by 289

Externally controlled on-demand release of anti-HIV drug using magneto-electric nanoparticles as carriers

Nair, M., Guduru, R., Liang, P., Hong, J., Sagar, V., & Khizroev, S. (2013) · Nature Communications · doi:10.1038/ncomms2717 · Cited by 287

Revealing the Binding Structure of the Protein Corona on Gold Nanorods Using Synchrotron Radiation-Based Techniques: Understanding the Reduced Damage in Cell Membranes

Wang, L., Li, J., Pan, J., Jiang, X., Ji, Y., Li, Y., Qu, Y., Zhao, Y., Wu, X., & Chen, C. (2013) · Journal of the American Chemical Society · doi:10.1021/ja406924v · Cited by 287

A Thermoresponsive Bubble-Generating Liposomal System for Triggering Localized Extracellular Drug Delivery

Chen, K.-J., Liang, H.-F., Chen, H.-L., Wang, Y., Cheng, P.-Y., Liu, H.-L., Xia, Y., & Sung, H.-W. (2013) · ACS Nano · doi:10.1021/nn304474j · Cited by 279

Synthesis of Reversible Shell Cross-Linked Micelles for Controlled Release of Bioactive Agents

Li, Y., Lokitz, B. S., Armes, S. P., & McCormick, C. L. (2006) · Macromolecules · doi:10.1021/ma0604035 · Cited by 278

A one-step strategy for thermal- and pH-responsive graphene oxide interpenetrating polymer hydrogel networks

Sun, S., & Wu, P. (2011) · Journal of Materials Chemistry · doi:10.1039/c1jm10276a · Cited by 276

Quantum dots, lighting up the research and development of nanomedicine

Wang, Y., & Chen, L. (2011) · Nanomedicine: Nanotechnology, Biology and Medicine · doi:10.1016/j.nano.2010.12.006 · Cited by 273

Thermo and pH dual responsive, polymer shell coated, magnetic mesoporous silica nanoparticles for controlled drug release

Chang, B., Sha, X., Guo, J., Jiao, Y., Wang, C., & Yang, W. (2011) · Journal of Materials Chemistry · doi:10.1039/c1jm10631g · Cited by 273

Synthesis of Size-Tunable Anatase TiO2 Nanospindles and Their Assembly into Anatase@Titanium Oxynitride/Titanium Nitride−Graphene Nanocomposites for Rechargeable Lithium Ion Batteries with High Cycling Performance

Qiu, Y., Yan, K., Yang, S., Jin, L., Deng, H., & Li, W. (2010) · ACS Nano · doi:10.1021/nn101603g · Cited by 269

Redox-Responsive Nanoparticles from the Single Disulfide Bond-Bridged Block Copolymer as Drug Carriers for Overcoming Multidrug Resistance in Cancer Cells

Wang, Y.-C., Wang, F., Sun, T.-M., & Wang, J. (2011) · Bioconjugate Chemistry · doi:10.1021/bc200139n · Cited by 268

Chitin nanofibrils/chitosan glycolate composites as wound medicaments

Muzzarelli, R. A. A., Morganti, P., Morganti, G., Palombo, P., Palombo, M., Biagini, G., Mattioli Belmonte, M., Giantomassi, F., Orlandi, F., & Muzzarelli, C. (2007) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2007.04.008 · Cited by 266

Mucoadhesive and thermogelling systems for vaginal drug delivery

Caramella, C. M., Rossi, S., Ferrari, F., Bonferoni, M. C., & Sandri, G. (2015) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2015.02.001 · Cited by 264

Oxidatively Modified Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) and Alzheimer's Disease: Many Pathways to Neurodegeneration

Butterfield, D. A., Hardas, S. S., & Lange, M. L. B. (2010) · Journal of Alzheimer's Disease · doi:10.3233/jad-2010-1375 · Cited by 262

Mannose‐Functionalized Mesoporous Silica Nanoparticles for Efficient Two‐Photon Photodynamic Therapy of Solid Tumors

Gary‐Bobo, M., Mir, Y., Rouxel, C., Brevet, D., Basile, I., Maynadier, M., Vaillant, O., Mongin, O., Blanchard‐Desce, M., Morère, A., et al. (2011) · Angewandte Chemie International Edition · doi:10.1002/anie.201104765 · Cited by 261

Dendronized heparin−doxorubicin conjugate based nanoparticle as pH-responsive drug delivery system for cancer therapy

She, W., Li, N., Luo, K., Guo, C., Wang, G., Geng, Y., & Gu, Z. (2013) · Biomaterials · doi:10.1016/j.biomaterials.2012.12.017 · Cited by 258

Glutathione-Sensitive Stabilization of Block Copolymer Micelles Composed of Antisense DNA and Thiolated Poly(ethylene glycol)-block-poly(l-lysine): A Potential Carrier for Systemic Delivery of Antisense DNA

Kakizawa, Y., Harada, A., & Kataoka, K. (2001) · Biomacromolecules · doi:10.1021/bm000142l · Cited by 256

Magnetically Triggered Nanocomposite Membranes: A Versatile Platform for Triggered Drug Release

Hoare, T. R., Timko, B. P., Santamarı́a, J., et al. (2011) · DSpace@MIT (Massachusetts Institute of Technology) · Cited by 256

Low levels of copper disrupt brain amyloid-β homeostasis by altering its production and clearance

Singh, I., Sagare, A. P., Coma, M., Perlmutter, D., Gelein, R., Bell, R. D., Deane, R. J., Zhong, E., Parisi, M., Ciszewski, J., et al. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1302212110 · Cited by 254

High-Frequency, Magnetic-Field-Responsive Drug Release from Magnetic Nanoparticle/Organic Hybrid Based on Hyperthermic Effect

Hayashi, K., Ono, K., Suzuki, H., Sawada, M., Moriya, M., Sakamoto, W., & Yogo, T. (2010) · ACS Applied Materials & Interfaces · doi:10.1021/am100237p · Cited by 254

Intracellular drug release nanosystems

Meng, F., Cheng, R., Deng, C., & Zhong, Z. (2012) · Materials Today · doi:10.1016/s1369-7021(12)70195-5 · Cited by 250

Shell-Detachable Micelles Based on Disulfide-Linked Block Copolymer As Potential Carrier for Intracellular Drug Delivery

Tang, L.-Y., Wang, Y.-C., Li, Y., Du, J.-Z., & Wang, J. (2009) · Bioconjugate Chemistry · doi:10.1021/bc900144m · Cited by 247

Magnetically Triggered Nanocomposite Membranes: A Versatile Platform for Triggered Drug Release

Hoare, T., Timko, B. P., Santamaria, J., Goya, G. F., Irusta, S., Lau, S., Stefanescu, C. F., Lin, D., Langer, R., & Kohane, D. S. (2011) · Nano Letters · doi:10.1021/nl200494t · Cited by 247

Intravenous magnetic nanoparticle cancer hyperthermia

Hainfeld, J., & Huang (2013) · International Journal of Nanomedicine · doi:10.2147/ijn.s43770 · Cited by 245

Exploiting Intrinsic Nanoparticle Toxicity: The Pros and Cons of Nanoparticle-Induced Autophagy in Biomedical Research

Peynshaert, K., Manshian, B. B., Joris, F., Braeckmans, K., De Smedt, S. C., Demeester, J., & Soenen, S. J. (2014) · Chemical Reviews · doi:10.1021/cr400372p · Cited by 244

Effect of the protein corona on nanoparticles for modulating cytotoxicity and immunotoxicity

Khang, D., Lee, Y. K., Choi, E.-J., Webster, T. J., & Kim, S.-H. (2014) · International Journal of Nanomedicine · doi:10.2147/ijn.s72998 · Cited by 244

Synthesis of graphene from natural and industrial carbonaceous wastes

Akhavan, O., Bijanzad, K., & Mirsepah, A. (2014) · RSC Advances · doi:10.1039/c4ra01550a · Cited by 242

Glucose-oxidase Based Self-Destructing Polymeric Vesicles

Napoli, A., Boerakker, M. J., Tirelli, N., Nolte, R. J. M., Sommerdijk, N. A. J. M., & Hubbell, J. A. (2004) · Langmuir · doi:10.1021/la0357054 · Cited by 241

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