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[1] Role of free radicals and catalytic metal ions in human disease: An overview
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“Possibly the commonest means by which such much more damaging species, in particular the hydroxyl radical, are created is by reaction with unliganded or incompletely liganded iron ions [61-63].”
In the citing paper
“Possibly the commonest means by which such much more damaging species, in particular the hydroxyl radical, are created is by reaction with unliganded or incompletely liganded iron ions [61-63].”
In the citing paper
“iron ions may catalyze free radical generation in biological systems 3-5 thus playing a key role in the toxicity of several mineral dusts 6-8 .”
In the citing paper
“This can be explained by the fact, that superoxide radical is necessary to achieve redox cycling of metal ions (Halliwell and Gutteridge 1990).”
From Reactive Oxygen Species, Toxicity, Oxidative Stress, and Antioxidants: Chronic Diseases and Aging (2023) · cites this paper as Halliwell and Gutteridge 1990
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Cites
Free radicals in biology and medicine
Gutteridge, J. M. C. (1991) · General Pharmacology The Vascular System · doi:10.1016/0306-3623(91)90478-o · Cited by 17,178
Self-citationEpstein, F. H., Steinberg, D. I., Parthasarathy, S., Carew, T. E., Khoo, J. C., & Witztum, J. L. (1989) · New England Journal of Medicine · doi:10.1056/nejm198904063201407 · Cited by 6,425
Oxygen-Derived Free Radicals in Postischemic Tissue Injury
Epstein, F. H., & McCord, J. M. (1985) · New England Journal of Medicine · doi:10.1056/nejm198501173120305 · Cited by 5,399
Oxygen toxicity, oxygen radicals, transition metals and disease
Halliwell, B., & Gutteridge, J. M. C. (1984) · Biochemical Journal · doi:10.1042/bj2190001 · Cited by 5,330
Self-citationThe Pathogenesis of Atherosclerosis — An Update
Ross, R. (1986) · New England Journal of Medicine · doi:10.1056/nejm198602203140806 · Cited by 4,885
Free Radicals in Biology and Medicine
Land, E. J. (1990) · International Journal of Radiation Biology · doi:10.1080/09553009014552071 · Cited by 4,871
Fridovich (1978) · doi:10.1126/science.210504 · Cited by 3,329
Walling, C. T. (1975) · Accounts of Chemical Research · doi:10.1021/ar50088a003 · Cited by 2,890
Prooxidant States and Tumor Promotion
Cerutti, P. (1985) · Science · doi:10.1126/science.2981433 · Cited by 2,513
Anti-cachectin/TNF monoclonal antibodies prevent septic shock during lethal bacteraemia
Tracey, K. J., Fong, Y., Hesse, D. G., Manogue, K. R., Lee, A. T., Kuo, G. C., Lowry, S. F., & Cerami, A. (1987) · Nature · doi:10.1038/330662a0 · Cited by 2,448
Research works printed but not linked: 73
- Evensen, 1984, Cancer Res., 44, 482
- Hasan, 1986, 83, 4604
- Singh, 1981, Bull. Eur. Physiopathol. Respir., 17, 31
- Albrich, 1981, 78, 210
- Weiss, 1986, Acta Physiol. Scand. Suppl., 548, 9
- Fridovich, 1974, Adv. Enzymol., 41, 35
- Van Loon, 1986, 83, 3820
- Farr, 1986, 83, 8268
- Williams, 1983, Ann. N.Y. Acad. Sci., 45, 478
- Schraufstatter, 1987, Int. J. Tissue React., 9, 317
- Etherington, 1981, Acta Biol. Med. Ger., 40, 1625
- Kozlov, 1973, Russ. J. Phys. Chem. (Engl. Transl.), 47, 338
- Johnson, 1985, Chem. Commun., 407
- Halliwell, 1988, ISI Atlas Sci. Biochem., 1, 48
- Halliwell, 1989, Agents Actions Suppl., 26, 223
- Finkelstein, 1979, Mol. Pharmacol., 16, 676
- Finkelstein, 1981, Mol. Pharmacol., 21, 262
- Sagone, 1983, J. Lab. Clin. Med., 101, 196
- Dizdaroglu, 1986, BioTechniques, 4, 536
- Curtis, 1988, 85, 3422
- Spector, 1984, 43, 196
- Creeth, 1982, IRCS Med. Sci., 10, 548
- Richardson, 1983, Chem. Ind. (London), 4, 498
- Watt, 1988, 85, 7457
- Morris, 1983, 42, 1716
- Bannister, 1984, Life Chem. Rep., 2, 64
- Gutteridge, 1984, Biochem. Int., 8, 89
- Gutteridge, 1987, Life Chem. Rep., 4, 113
- Gutteridge, 1984, Med. Biol., 62, 101
- Hochstein, 1981, 40, 183
- Esterbauer, 1988, ISI Atlas Sci. Biochem., 1, 311
- Comporti, 1985, Lab. Invest., 53, 599
- Muliawan, 1980, Res. Commun. Chem. Pathol. Pharmacol., 30, 509
- Orrenius, 1988, ISI Atlas Sci. Pharmacol., 1, 319
- Sohal, 1986, 2, 117
- Docampo, 1986, 45, 2471
- Chellman, 1986, 83, 8087
- Oldham, 1988, Surgery, 104, 272
- McGill, 1988, Clin. Chem., 33, B33
- Munro, 1988, Lab. Invest., 58, 249
- Quinn, 1988, 85, 2805
- Quinn, 1987, 84, 2995
- Yokode, 1988, 85, 2344
- Ball, 1987, Arch. Pathol. Lab. Med., 111, 1134
- Ball, 1987, Br. J. Exp. Pathol., 68, 427
- Schuh, 1978, 75, 3173
- Gutteridge, 1988, Vol. 2, 1
- Esterbauer, 1981, IRCS Med. Sci. Biochem., 9, 749
- Gutteridge, 1983, J. Appl. Biochem., 5, 293
- Wills, 1964, Biochim. Biophys. Acta, 84, 475
- J. A. Buege and S. D. Aust, this series, Vol. 30, p. 302.
- McCord, 1987, 46, 2402
- Parks, 1986, Am. J. Physiol., 250, G749
- Hernandez, 1987, Am. J. Physiol., 253, G49
- Watts, 1965, J. Lab. Clin. Med., 66, 688
- Parks, 1988, Am. J. Physiol., 254, G768
- Brown, 1988, Surgery, 104, 266
- Granger, 1988, Am. J. Physiol., 255, H1269
- Grisham, 1986, Am. J. Physiol., 251, G567
- Bitterman, 1988, 188, 265
- Manson, 1983, Circ. Shock, 10, 205
- Saez, 1984, Circ. Shock, 12, 229
- Simpson, 1987, J. Lab. Clin. Med., 110, 13
- Bernier, 1988, Am. J. Physiol., 254, H862
- Del Nido, 1987, Circulation, 76, V174
- Zweier, 1988, 85, 4046
- Jarasch, 1986, Acta Physiol. Scand. Suppl., 548, 39
- Ratych, 1987, Surgery, 102, 122
- Sneddon, 1988, 85, 2800
- Baud, 1986, Am. J. Physiol., 251, F765
- Southard, 1987, Surgery, 101, 566
- Parks, 1983, Surgery, 94, 428
- Sarr, 1987, Surgery, 101, 342
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Metadata
- Authors
- Halliwell, B., & Gutteridge, J. M. C.
- ORCID
- Halliwell, Barry
- Venue
- Methods in Enzymology
- Publisher
- Elsevier
- Published
- 1990
- Volume
- 186
- Pages
- 1-85
- ISSN
- 0076-6879 (ISSN-L)
- OpenAlex
- W1734082729
- Cited by
- 4,994
- References
- 562
- Citations by year
- 2026: 16 · 2025: 47 · 2024: 52 · 2023: 78 · 2022: 101 · 2021: 96 · 2020: 95 · 2019: 96 · 2018: 103 · 2017: 129 · 2016: 122 · 2015: 142 · 2014: 184 · 2013: 196 · 2012: 214
- FWCI
- 53.61
- Type
- book chapter
- Language
- en
- Open access
- closed
- Locations
- Methods in enzymology on CD-ROM/Methods in enzymology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Biochemistry (medical) › Antioxidant Activity and Oxidative Stress
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Redox biology and oxidative stress
- Health Sciences › Nursing › Nutrition and Dietetics › Trace Elements in Health
- Keywords
- free radicals, catalytic metal ions, transition metals, iron metabolism, copper metabolism, chelation therapy, lipid peroxidation, diene conjugation, thiobarbituric acid assay, oxidative damage, human disease, toxicology
- MeSH terms
- Disease, Free Radicals, Humans, Ions, Metals, Superoxides
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