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A longitudinal study on the mental health of general population during the COVID-19 epidemic in China

Open access
Wang, Cuiyan, Pan, Riyu, Wan, Xiaoyang, Tan, Yilin, Xu, Linkang, McIntyre, Roger S., Choo, Faith N., Tran, Bach +3 more·2020·Brain, Behavior, and Immunity

Abstract

In addition to being a public physical health emergency, Coronavirus disease 2019 (COVID-19) affected global mental health, as evidenced by panic-buying worldwide as cases soared. Little is known about changes in levels of psychological impact, stress, anxiety and depression during this pandemic. This longitudinal study surveyed the general population twice - during the initial outbreak, and the epidemic's peak four weeks later, surveying demographics, symptoms, knowledge, concerns, and precautionary measures against COVID-19. There were 1738 respondents from 190 Chinese cities (1210 first-survey respondents, 861 s-survey respondents; 333 respondents participated in both). Psychological impact and mental health status were assessed by the Impact of Event Scale-Revised (IES-R) and the Depression, Anxiety and Stress Scale (DASS-21), respectively. IES-R measures PTSD symptoms in survivorship after an event. DASS -21 is based on tripartite model of psychopathology that comprise a general distress construct with distinct characteristics. This study found that there was a statistically significant longitudinal reduction in mean IES-R scores (from 32.98 to 30.76, p < 0.01) after 4 weeks. Nevertheless, the mean IES-R score of the first- and second-survey respondents were above the cut-off scores (>24) for PTSD symptoms, suggesting that the reduction in scores was not clinically significant. During the initial evaluation, moderate-to-severe stress, anxiety and depression were noted in 8.1%, 28.8% and 16.5%, respectively and there were no significant longitudinal changes in stress, anxiety and depression levels (p > 0.05). Protective factors included high level of confidence in doctors, perceived survival likelihood and low risk of contracting COVID-19, satisfaction with health information, personal precautionary measures. As countries around the world brace for an escalation in cases, Governments should focus on effective methods of disseminating unbiased COVID-19 knowledge, teaching correct containment methods, ensuring availability of essential services/commodities, and providing sufficient financial support.

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Crossref · 10.1016/j.bbi.2020.04.028

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  • In a sample of 1,173 undergraduate and postgraduate students from a UK university, over 50% surpassed clinical thresholds for anxiety and depression (21).

    “In a sample of 1,173 undergraduate and postgraduate students from a university in the UK, over 50% of respondents surpassed clinical thresholds for anxiety and depression (21).”

    From Mental health status and coping strategies during COVID-19 pandemic among university students in Central Serbia (2023) · cites this paper as [21]

    The Results (Comparison of respondents and mental health status; page unavailable) report 1,738 individual respondents from cities in China, not 1,173 undergraduate and postgraduate students at a UK university. The cited paper reports anxiety and depression scores but does not establish the claimed proportion above clinical thresholds. (LLM, conf=0.90)

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  • Recent international studies have reported increased symptoms of anxiety, depression, sleep disorders, and psychological distress during lockdown.

    “recent international studies have reported increased symptoms of anxiety, depression, sleep disorders, and psychological distress during lockdown (4–10)”

    From The Evolution of Psychological and Behavioral Consequences of Self-Isolation During Lockdown: A Longitudinal Study Across United Kingdom and Italy (2022) · cites this paper as [10]

    The Discussion (page unavailable) reports stable stress, anxiety, and depression scores across the two surveys and a small reduction—not an increase—in overall psychological impact. It notes greater impact in a younger subgroup during prolonged lockdown, but does not report increased symptoms across the general population; the passages found also do not address sleep disorders. (LLM, conf=0.86)

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  • A strength of the present study is that it addresses the absence of longitudinal studies examining the impact of COVID-19 on adolescents.

    “Although a strength of the present study is that it addresses the absence of longitudinal studies examining the impact of COVID‐19 on adolescents (McGinty et al., 2020; Wang et al., 2020), there are several limitations that must be acknowledged.”

    From Adolescents' longitudinal trajectories of mental health and loneliness: The impact of COVID‐19 school closures (2022) · cites this paper as Wang et al., 2020

    The Introduction says longitudinal evidence on COVID-19’s mental-health impact was lacking, but it frames that gap around the general population in China, not adolescents specifically. The Results include respondents aged 12–21.4, but do not establish an absence of longitudinal studies focused on adolescents. The citing authors’ description of their own study as a strength is not a claim this source can verify. (LLM, conf=0.85)

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  • In the general public, the COVID-19 pandemic is associated with greater levels of psychological distress and psychopathological problems such as depression, anxiety, and post-traumatic stress symptoms.

    “Recent research has shown that, in the general public, the COVID-19 pandemic is associated with greater levels of psychological distress and a range of psychopathological problems such as depression, anxiety, and post-traumatic stress symptoms (e.g., Gao et al., 2020; Qiu et al., 2020; Wang et al., 2020).”

    From Why did all the toilet paper disappear? Distinguishing between panic buying and hoarding during COVID-19 (2021) · cites this paper as Wang et al., 2020

    The Results section (page not provided) reports PTSD-symptom scores above the cutoff in both surveys and measures stress, anxiety, and depression in the Chinese general public during the outbreak. It does not establish that these levels were greater than before the pandemic: stress, anxiety, and depression remained stable between surveys, while psychological-impact scores fell slightly. (LLM, conf=0.82)

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  • Our research suggested significant deleterious effects after the first week, followed by stabilization of scores during the subsequent quarantine period, supporting the view that individuals may adapt to the negative consequences of social isolation and home confinement.

    “Consistent with the literature, our research suggested significant deleterious effects after the first week, followed by stabilization of the scores during the subsequent quarantine period, supporting the view that individuals may adapt to the negative consequences of social isolation and home confinement (10, 46, 93).”

    From The Evolution of Psychological and Behavioral Consequences of Self-Isolation During Lockdown: A Longitudinal Study Across United Kingdom and Italy (2022) · cites this paper as [10]

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6 of the 31 references couldn’t be matched to a known paper.

Research works printed but not linked: 1

  1. Europe on Lockdown From COVID-19. Jewish Journal, 2020. (Accessed March 22, 2020, at https://jewishjournal.com/commentary/opinion/312317/europe-on-lockdown-from-covid-19/).

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Authors
Wang, C., Pan, R., Wan, X., Tan, Y., Xu, L., McIntyre, R. S., Choo, F. N., Tran, B., Ho, R., Sharma, V. K., & Ho, C.
Affiliations
  • Huaibei Normal University (CN)
  • University Health Network (CA)
  • National University of Singapore (SG)
  • Johns Hopkins University (US)
Corresponding author
Ho, Roger
Venue
Brain, Behavior, and Immunity
Publisher
Elsevier BV
Published
2020-07
Volume
87
Pages
40-48
ISSN
0889-1591 (ISSN-L)
OpenAlex
W3016216556
Cited by
2,571
References
31
Citations by year
2026: 32 · 2025: 103 · 2024: 176 · 2023: 347 · 2022: 611 · 2021: 845 · 2020: 455 · 2017: 1
FWCI
225.98
Type
journal article
Language
en
Open access
Locations
  • Brain Behavior and Immunity (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
  • National University of Singapore (submittedVersion)
  • Rare & Special e-Zone (The Hong Kong University of Science and Technology) (submittedVersion)
Funders
  • National University of Singapore (R-722-000-004-731)
  • Huaibei Normal University
Topics
  • Social Sciences › Psychology › Clinical Psychology › COVID-19 and Mental Health
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Maternal Mental Health During Pregnancy and Postpartum
  • Social Sciences › Psychology › Social Psychology › Mental Health Treatment and Access
Keywords
COVID-19 pandemic, mental health, psychological impact, anxiety, depression, stress, post-traumatic stress disorder, general population, protective factors, perceived infection risk, precautionary measures, China
MeSH terms
Betacoronavirus, Internet-Based Intervention, COVID-19, SARS-CoV-2, Adolescent, Adult, Anxiety, Child, China, Depression, Female, Humans, Longitudinal Studies, Male, Masks, Mental Health, Middle Aged, Pneumonia, Viral, Psychotherapy, Stress Disorders, Post-Traumatic, Stress, Psychological, Health Behavior, Coronavirus Infections, Young Adult, Epidemics, Pandemics, Hand Hygiene

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