Cited by 355Neuroscience and Neural EngineeringRetinal Development and DisordersTactile and Sensory Interactions

The DOI matches its Crossref record; 182 of the 189 references it cites were found in a registry or an index.

The Argus® II Retinal Prosthesis System

Luo, Yvonne Hsu-Lin, da Cruz, Lyndon·2016·Progress in Retinal and Eye Research

DOI 10.1016/j.preteyeres.2015.09.003

Open this paper in CoChat — free account

Abstract

The Argus(®) II Retinal Prosthesis System (Second Sight Medical Products) is the first prosthetic vision device to obtain regulatory approval in both Europe and the USA. As such it has entered the commercial market as a treatment for patients with profound vision loss from end-stage outer retinal disease, predominantly retinitis pigmentosa. To date, over 100 devices have been implanted worldwide, representing the largest group of patients currently treated with visual prostheses. The system works by direct stimulation of the relatively preserved inner retina via epiretinal microelectrodes, thereby replacing the function of the degenerated photoreceptors. Visual information from a glasses-mounted video camera is converted to a pixelated image by an external processor, before being transmitted to the microelectrode array at the macula. Elicited retinal responses are then relayed via the normal optic nerve to the cortex for interpretation. We reviewed the animal and human studies that led to the development of the Argus(®) II device. A sufficiently robust safety profile was demonstrated in the phase I/II clinical trial of 30 patients. Improvement of function in terms of orientation and mobility, target localisation, shape and object recognition, and reading of letters and short unrehearsed words have also been shown. There remains a wide variability in the functional outcomes amongst the patients and the factors contributing to these performance differences are still unclear. Future developments in terms of both software and hardware aimed at improving visual function have been proposed. Further experience in clinical outcomes is being acquired due to increasing implantation.

Integrity signals

Registry

Crossref · 10.1016/j.preteyeres.2015.09.003

Cites

182 of 182 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

A quantitative description of membrane current and its application to conduction and excitation in nerve
Hodgkin, A. L., & Huxley, A. F. (1952) · The Journal of Physiology · doi:10.1113/jphysiol.1952.sp004764 · Cited by 23,191
A model of saliency-based visual attention for rapid scene analysis
Itti, L., Christof Koch, A., & Niebur, E. (1998) · IEEE Transactions on Pattern Analysis and Machine Intelligence · doi:10.1109/34.730558 · Cited by 11,289
Global prevalence of age-related macular degeneration and disease burden projection for 2020 and 2040: a systematic review and meta-analysis
Wong, W. L., Su, X., Li, X., Cheung, C. M. G., Klein, R., Cheng, C., & Wong, T. Y. (2014) · The Lancet Global Health · doi:10.1016/s2214-109x(13)70145-1 · Cited by 5,545
Retinitis pigmentosa
Hartong, D. T., Berson, E. L., & Dryja, T. P. (2006) · The Lancet · doi:10.1016/s0140-6736(06)69740-7 · Cited by 2,924
Topography of ganglion cells in human retina
Curcio, C. A., & Allen, K. A. (1990) · The Journal of Comparative Neurology · doi:10.1002/cne.903000103 · Cited by 1,849
The development and application of optogenetics
Fenno, L., Yizhar, O., & Deisseroth, K. (2011) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-061010-113817 · Cited by 1,822
Activation of the primary visual cortex by Braille reading in blind subjects
Sadato, N., Pascual-Leone, A., Grafman, J., Ibañez, V., Deiber, M.-P., Dold, G., & Hallett, M. (1996) · Nature · doi:10.1038/380526a0 · Cited by 1,253
Better speech recognition with cochlear implants
Wilson, B. S., Finley, C. C., Lawson, D. T., Wolford, R. D., Eddington, D. K., & Rabinowitz, W. M. (1991) · Nature · doi:10.1038/352236a0 · Cited by 1,211
The sensations produced by electrical stimulation of the visual cortex
Brindley, G. S., & Lewin, W. S. (1968) · The Journal of Physiology · doi:10.1113/jphysiol.1968.sp008519 · Cited by 1,170
Cross-modal plasticity: where and how?
Bavelier, D., & Neville, H. J. (2002) · Nature Reviews Neuroscience · doi:10.1038/nrn848 · Cited by 1,040
Neural remodeling in retinal degeneration
Marc, R. E., Jones, B. W., Watt, C. B., & Strettoi, E. (2003) · Progress in Retinal and Eye Research · doi:10.1016/s1350-9462(03)00039-9 · Cited by 891
Visual perception in a blind subject with a chronic microelectronic retinal prosthesis
Humayun, M. S., Weiland, J. D., Fujii, G. Y., Greenberg, R., Williamson, R., Little, J., Mech, B., Cimmarusti, V., Van Boemel, G., Dagnelie, G., et al. (2003) · Vision Research · doi:10.1016/s0042-6989(03)00457-7 · Cited by 856
Subretinal electronic chips allow blind patients to read letters and combine them to words
Zrenner, E., Bartz-Schmidt, K. U., Benav, H., Besch, D., Bruckmann, A., Gabel, V.-P., Gekeler, F., Greppmaier, U., Harscher, A., Kibbel, S., et al. (2011) · Proceedings of the Royal Society B: Biological Sciences · doi:10.1098/rspb.2010.1747 · Cited by 819
Retinal gene therapy in patients with choroideremia: initial findings from a phase 1/2 clinical trial
MacLaren, R. E., Groppe, M., Barnard, A. R., Cottriall, C. L., Tolmachova, T., Seymour, L., Clark, K. R., During, M. J., Cremers, F. P. M., Black, G. C. M., et al. (2014) · The Lancet · doi:10.1016/s0140-6736(13)62117-0 · Cited by 796
Interim results from the international trial of Second Sight's visual prosthesis
Humayun, M. S., Dorn, J. D., da Cruz, L., Dagnelie, G., Sahel, J.-A., Stanga, P. E., Cideciyan, A. V., Duncan, J. L., Eliott, D., Filley, E., et al. (2012) · Ophthalmology · doi:10.1016/j.ophtha.2011.09.028 · Cited by 700
Preservation of the Inner Retina in Retinitis Pigmentosa
Santos, A. (1997) · Archives of Ophthalmology · doi:10.1001/archopht.1997.01100150513011 · Cited by 651
Visual Perception Elicited by Electrical Stimulation of Retina in Blind Humans
Humayun, M. S. (1996) · Archives of Ophthalmology · doi:10.1001/archopht.1996.01100130038006 · Cited by 602
Pattern electrical stimulation of the human retina
Humayun, M. S., de Juan, E., Weiland, J. D., Dagnelie, G., Katona, S., Greenberg, R. J., & Suzuki, S. (1999) · Vision Research · doi:10.1016/s0042-6989(99)00052-8 · Cited by 598
Artificial Vision for the Blind by Connecting a Television Camera to the Visual Cortex
Dobelle, W. H. (2000) · ASAIO Journal · doi:10.1097/00002480-200001000-00002 · Cited by 584
Discussion
Unknown (1998) · Progress in Retinal and Eye Research · doi:10.1016/s1350-9462(97)00012-8 · Cited by 570
Noninvasive optical inhibition with a red-shifted microbial rhodopsin
Miri, M. L., Busskamp, V., Young, A., Ogawa, M., Ramanlal, S. B., Forest, C. R., Chow, B. Y., Han, X., Lin, Y., Roska, B., et al. (2014) · DSpace@MIT (Massachusetts Institute of Technology) · Cited by 554
The Artificial Silicon Retina Microchip for the Treatment of VisionLoss From Retinitis Pigmentosa
Chow, A. Y. (2004) · Archives of Ophthalmology · doi:10.1001/archopht.122.4.460 · Cited by 512
Polymerization of the conducting polymer poly(3,4-ethylenedioxythiophene) (PEDOT) around living neural cells
Richardson-Burns, S. M., Hendricks, J. L., Foster, B., Povlich, L. K., Kim, D., & Martin, D. C. (2006) · Biomaterials · doi:10.1016/j.biomaterials.2006.11.026 · Cited by 505
Morphometric Analysis of Macular Photoreceptors and Ganglion Cells in Retinas With Retinitis Pigmentosa
Stone, J. L. (1992) · Archives of Ophthalmology · doi:10.1001/archopht.1992.01080230134038 · Cited by 480
Perceptual efficacy of electrical stimulation of human retina with a microelectrode array during short-term surgical trials
Rizzo, J. F., Wyatt, J., Loewenstein, J., Kelly, S., & Shire, D. (2003) · Investigative Opthalmology & Visual Science · doi:10.1167/iovs.02-0817 · Cited by 478
Retinal remodeling triggered by photoreceptor degenerations
Jones, B. W., Watt, C. B., Frederick, J. M., Baehr, W., Chen, C., Levine, E. M., Milam, A. H., Lavail, M. M., & Marc, R. E. (2003) · Journal of Comparative Neurology · doi:10.1002/cne.10703 · Cited by 476
Artificial vision with wirelessly powered subretinal electronic implant alpha-IMS
Stingl, K., Bartz-Schmidt, K. U., Besch, D., Braun, A., Bruckmann, A., Gekeler, F., Greppmaier, U., Hipp, S., Hörtdörfer, G., Kernstock, C., et al. (2013) · Proceedings of the Royal Society B: Biological Sciences · doi:10.1098/rspb.2013.0077 · Cited by 473
Photovoltaic retinal prosthesis with high pixel density
Mathieson, K., Loudin, J., Goetz, G. A., Huie, P., Wang, L., Kamins, T. I., Galambos, L., Smith, R., Harris, J. S., Sher, A., et al. (2012) · Nature Photonics · doi:10.1038/nphoton.2012.104 · Cited by 460
Vitrectomy: a pars plana approach.
Machemer, R., Buettner, H., Norton, E. W., & Parel, J.-M. A. (1971) · PubMed · Cited by 452
Retinal Prosthesis for the Blind
Margalit, E., Maia, M., Weiland, J. D., Greenberg, R. J., Fujii, G. Y., Torres, G. F., Piyathaisere, D. V., O’Hearn, T. M., Liu, W., Lazzi, G., et al. (2002) · Survey of Ophthalmology · doi:10.1016/s0039-6257(02)00311-9 · Cited by 433
Retinal remodeling during retinal degeneration
Jones, B. W., & Marc, R. E. (2005) · Experimental Eye Research · doi:10.1016/j.exer.2005.03.006 · Cited by 430
Neural Stimulation with a Carbon Nanotube Microelectrode Array
Wang, K., Fishman, H. A., Dai, H., & Harris, J. S. (2006) · Nano Letters · doi:10.1021/nl061241t · Cited by 420
Vitrectomy--a pars plana approach.
Satapathy, M., Goud, A. S., Gv, G., & Ss, M. (1981) · PubMed · Cited by 393
Subretinal visual implant alpha IMS - clinical trial interim report
Stingl, K., Bartz-Schmidt, K. U., Besch, D., Chee, C. K., Cottriall, C. L., Gekeler, F., Groppe, M., Jackson, T. L., MacLaren, R. E., Koitschev, A., et al. (2015) · Vision Research · doi:10.1016/j.visres.2015.03.001 · Cited by 387
In vitro electrical properties for iridium oxide versus titanium nitride stimulating electrodes
Weiland, J. D., Anderson, D. J., & Humayun, M. S. (2002) · IEEE Transactions on Biomedical Engineering · doi:10.1109/tbme.2002.805487 · Cited by 382
Electrical stimulation with Pt electrodes. VIII. Electrochemically safe charge injection limits with 0.2 ms pulses (neuronal application)
Rose, T. L., & Robblee, L. S. (1990) · IEEE Transactions on Biomedical Engineering · doi:10.1109/10.61038 · Cited by 366
Methods and Perceptual Thresholds for Short-Term Electrical Stimulation of Human Retina with Microelectrode Arrays
Rizzo, J. F., Wyatt, J. L., Loewenstein, J. I., Kelly, S. K., & Shire, D. B. (2003) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.02-0819 · Cited by 362
Electrochemical Considerations for Safe Electrical Stimulation of the Nervous System with Platinum Electrodes
Brummer, S. B., & Turner, M. J. (1977) · IEEE Transactions on Biomedical Engineering · doi:10.1109/tbme.1977.326218 · Cited by 360
The Argus II epiretinal prosthesis system allows letter and word reading and long-term function in patients with profound vision loss
da Cruz, L., Coley, B. F., Dorn, J., Merlini, F., Filley, E., Christopher, P., Chen, F. K., Wuyyuru, V., Sahel, J., Stanga, P., et al. (2013) · British Journal of Ophthalmology · doi:10.1136/bjophthalmol-2012-301525 · Cited by 359
Five-year safety and performance results from the argus II retinal prosthesis system clinical trial.
da Cruz, L., Dorn, J. D., Humayun, M. S., Dagnelie, G., Handa, J., Barale, P.-O., Sahel, J.-A., Stanga, P. E., Hafezi, F., Safran, A. B., et al. (2016) · Ophthalmology · doi:10.1016/j.ophtha.2016.06.049 · Cited by 359
Electrical Stimulation of Mammalian Retinal Ganglion Cells With Multielectrode Arrays
Sekirnjak, C., Hottowy, P., Sher, A., Dąbrowski, W., Litke, A. M., & Chichilnisky, E. J. (2006) · Journal of Neurophysiology · doi:10.1152/jn.01168.2005 · Cited by 342
Photovoltaic restoration of sight with high visual acuity
Lorach, H., Goetz, G., Smith, R., Lei, X., Mandel, Y., Kamins, T. I., Mathieson, K., Huie, P., Harris, J. S., Sher, A., et al. (2015) · Nature Medicine · doi:10.1038/nm.3851 · Cited by 341
First-in-human trial of a novel suprachoroidal retinal prosthesis
Ayton, L. N., Blamey, P. J., Guymer, R. H., Luu, C. D., Nayagam, D. A. X., Sinclair, N. C., Shivdasani, M. N., Yeoh, J., McCombe, M. F., Briggs, R. J., et al. (2014) · PLoS ONE · doi:10.1371/journal.pone.0115239 · Cited by 333
A polymer optoelectronic interface restores light sensitivity in blind rat retinas
Ghezzi, D., Antognazza, M. R., Maccarone, R., Bellani, S., Lanzarini, E., Martino, N., Mete, M., Pertile, G., Bisti, S., Lanzani, G., et al. (2013) · Nature Photonics · doi:10.1038/nphoton.2013.34 · Cited by 327
The estimated prevalence and incidence of late stage age related macular degeneration in the UK
Owen, C. G., Jarrar, Z. A., Wormald, R., Cook, D. G., FLETCHER, A. E., & Rudnicka, A. R. (2012) · British Journal of Ophthalmology · doi:10.1136/bjophthalmol-2011-301109 · Cited by 318
Neural Reprogramming in Retinal Degeneration
Marc, R. E., Jones, B. W., Anderson, J. R., Kinard, K. I., MARSHAK, D. W., Wilson, J. H., Wensel, T. G., & Lucas, R. J. (2007) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.07-0032 · Cited by 312
A fully organic retinal prosthesis restores vision in a rat model of degenerative blindness
Maya‐Vetencourt, J. F., Ghezzi, D., Antognazza, M. R., Colombo, E., Mete, M., Feyen, P., Desii, A., Buschiazzo, A., Paolo, M. D., Marco, S. D., et al. (2017) · Nature Materials · doi:10.1038/nmat4874 · Cited by 294
Blind subjects implanted with the Argus II retinal prosthesis are able to improve performance in a spatial-motor task
Ahuja, A. K., Dorn, J. D., Caspi, A., McMahon, M. J., Dagnelie, G., daCruz, L., Stanga, P., Humayun, M. S., Greenberg, R. J., & Argus II Study Group (2011) · British Journal of Ophthalmology · doi:10.1136/bjo.2010.179622 · Cited by 289
The Scleral Buckling Procedures
Schepens, C. L. (1957) · A M A Archives of Ophthalmology · doi:10.1001/archopht.1957.00940010819003 · Cited by 287
Brief, Noninjurious Electric Waveform for Stimulation of the Brain
Lilly, J. C., Hughes, J. R., Alvord, E. C., & Galkin, T. W. (1955) · Science · doi:10.1126/science.121.3144.468 · Cited by 287
Long-Term Results from an Epiretinal Prosthesis to Restore Sight to the Blind
Ho, A. C., Humayun, M. S., Dorn, J. D., da Cruz, L., Dagnelie, G., Handa, J. T., Barale, P. O., Sahel, J., Stanga, P. E., Hafezi, F., et al. (2015) · Ophthalmology · doi:10.1016/j.ophtha.2015.04.032 · Cited by 262
How the Retina Works
Kolb, H. (2003) · American Scientist · doi:10.1511/2003.11.841 · Cited by 251
Optogenetic therapy for retinitis pigmentosa
Busskamp, V., Picaud, S. A., Sahel, J., & Roska, B. (2011) · Gene Therapy · doi:10.1038/gt.2011.155 · Cited by 247
Visual acuity impairment in patients with retinitis pigmentosa at age 45 years or older
Grover, S., Fishman, G. A., Anderson, R. J., Tozatti, M. S. V., Heckenlively, J. R., Weleber, R. G., Edwards, A. O., & Brown, J. (1999) · Ophthalmology · doi:10.1016/s0161-6420(99)90342-1 · Cited by 235
Photoreceptors at a glance
Molday, R. S., & Moritz, O. L. (2015) · Journal of Cell Science · doi:10.1242/jcs.175687 · Cited by 235
Mobility performance with a pixelized vision system.
Cha, K., Horch, K. W., & Normann, R. A. (1992) · Vision Research · doi:10.1016/0042-6989(92)90229-c · Cited by 226
Charge injection limits of activated iridium oxide electrodes with 0.2 ms pulses in bicarbonate buffered saline (neurological stimulation application)
Beebe, X., & Rose, T. L. (1988) · IEEE Transactions on Biomedical Engineering · doi:10.1109/10.2122 · Cited by 220
Retinal prosthetic strategy with the capacity to restore normal vision
Nirenberg, S., & Pandarinath, C. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1207035109 · Cited by 207
CRITERIA FOR SELECTING ELECTRODES FOR ELECTRICAL STIMULATION: THEORETICAL AND PRACTICAL CONSIDERATIONS
Brummer, S. B., Robblee, L. S., & Hambrecht, F. T. (1983) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1983.tb31628.x · Cited by 205
Simulation of a phosphene-based visual field: Visual acuity in a pixelized vision system
Cha, K., Horch, K., & Normann, R. A. (1992) · Annals of Biomedical Engineering · doi:10.1007/bf02368135 · Cited by 198
Interim results of a multicenter trial with the new electronic subretinal implant Alpha AMS in 15 Patients blind from inherited retinal degenerations.
Stingl, K., Schippert, R., Bartz-Schmidt, K. U., Besch, D., Cottriall, C. L., Edwards, T. L., Gekeler, F., Greppmaier, U., Kiel, K., Koitschev, A., et al. (2017) · Frontiers in Neuroscience · doi:10.3389/fnins.2017.00445 · Cited by 198
High-Resolution Electrical Stimulation of Primate Retina for Epiretinal Implant Design
Sekirnjak, C., Hottowy, P., Sher, A., Dąbrowski, W., Litke, A. M., & Chichilnisky, E. J. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.5138-07.2008 · Cited by 195
Fighting Blindness with Microelectronics
Zrenner, E. (2013) · Science Translational Medicine · doi:10.1126/scitranslmed.3007399 · Cited by 192
The functional performance of the Argus II retinal prosthesis
Stronks, H. C., & Dagnelie, G. (2014) · Expert Review of Medical Devices · doi:10.1586/17434440.2014.862494 · Cited by 189
Vitrectomy: A Pars Plana Approach
Shoch, D. E. (1976) · American Journal of Ophthalmology · doi:10.1016/0002-9394(76)90322-6 · Cited by 187
A computational model of electrical stimulation of the retinal ganglion cell
Greenberg, R. J., Velte, T. J., Humayun, M. S., Scarlatis, G. N., & de Juan, E. (1999) · IEEE Transactions on Biomedical Engineering · doi:10.1109/10.759051 · Cited by 185
Facial Recognition Using Simulated Prosthetic Pixelized Vision
Thompson, R. W., Barnett, G. D., Humayun, M. S., & Dagnelie, G. (2003) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.03-0341 · Cited by 180
Red‐shifted channelrhodopsin stimulation restores light responses in blind mice, macaque retina, and human retina
Sengupta, A., Chaffiol, A., Macé, É., Caplette, R., Desrosiers, M., Lampič, M., Forster, V., Marre, O., Lin, J. Y., Sahel, J., et al. (2016) · EMBO Molecular Medicine · doi:10.15252/emmm.201505699 · Cited by 180
What blindness can tell us about seeing again: merging neuroplasticity and neuroprostheses
Merabet, L. B., Rizzo, J. F., Amedi, A., Somers, D. C., & Pascual-Leone, A. (2005) · Nature reviews. Neuroscience · doi:10.1038/nrn1586 · Cited by 179
The detection of motion by blind subjects with the epiretinal 60-electrode (Argus II) retinal prosthesis
Dorn, J. D., Ahuja, A. K., Caspi, A., da Cruz, L., Dagnelie, G., Sahel, J.-A., Greenberg, R. J., McMahon, M. J., & Argus II Study Group, F. T. (2013) · JAMA Ophthalmology · doi:10.1001/2013.jamaophthalmol.221 · Cited by 177
How the Retina Works
Kolb, H. (2003) · American Scientist · doi:10.1511/2003.1.28 · Cited by 168
Visually Guided Performance of Simple Tasks Using Simulated Prosthetic Vision
Hayes, J. S., Yin, V. T., Piyathaisere, D. V., Weiland, J. D., Humayun, M. S., & Dagnelie, G. (2003) · Artificial Organs · doi:10.1046/j.1525-1594.2003.07309.x · Cited by 164
Frequency and amplitude modulation have different effects on the percepts elicited by retinal stimulation
Nanduri, D., Fine, I., Horsager, A., Boynton, G. M., Humayun, M. S., Greenberg, R. J., & Weiland, J. D. (2012) · Investigative Opthalmology & Visual Science · doi:10.1167/iovs.11-8401 · Cited by 163
Bipolar Surface Electrical Stimulation of the Vertebrate Retina
Humayun, M. S. (1994) · Archives of Ophthalmology · doi:10.1001/archopht.1994.01090130120028 · Cited by 158
A New Promoter Allows Optogenetic Vision Restoration with Enhanced Sensitivity in Macaque Retina
Chaffiol, A., Caplette, R., Jaillard, C., Brazhnikova, E., Desrosiers, M., Dubus, É., Duhamel, L., Macé, É., Marre, O., Benoit, P., et al. (2017) · Molecular Therapy · doi:10.1016/j.ymthe.2017.07.011 · Cited by 153
Feasibility Study of a Retinal Prosthesis
Caspi, A. (2009) · Archives of Ophthalmology · doi:10.1001/archophthalmol.2009.20 · Cited by 149
Thresholds for Activation of Rabbit Retinal Ganglion Cells with an Ultrafine, Extracellular Microelectrode
Jensen, R. J., Rizzo, J. F., Ziv, O. R., Grumet, A., & Wyatt, J. (2003) · Investigative Opthalmology & Visual Science · doi:10.1167/iovs.02-1041 · Cited by 145
Early changes in synaptic connectivity following progressive photoreceptor degeneration in RCS rats
Cuenca, N., Pinilla, I., Sauvé, Y., & Lund, R. D. (2005) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2005.04300.x · Cited by 145
Toward the development of a cortically based visual neuroprosthesis
Normann, R. A., Greger, B. A., House, P., Romero, S. F., Pelayo, F., & Fernandez, E. (2009) · Journal of Neural Engineering · doi:10.1088/1741-2560/6/3/035001 · Cited by 143
Photovoltaic retinal prosthesis: implant fabrication and performance
Wang, L., Mathieson, K., Kamins, T. I., Loudin, J., Galambos, L., Goetz, G. A., Sher, A., Mandel, Y., Huie, P., Lavinsky, D., et al. (2012) · Journal of Neural Engineering · doi:10.1088/1741-2560/9/4/046014 · Cited by 142
Real and virtual mobility performance in simulated prosthetic vision
Dagnelie, G., Keane, P. A., Narla, V., Yang, L., Weiland, J. D., & Humayun, M. S. (2007) · Journal of Neural Engineering · doi:10.1088/1741-2560/4/1/s11 · Cited by 136
Tissue Damage by Pulsed Electrical Stimulation
Butterwick, A., Vankov, A., Huie, P., Freyvert, Y., & Palanker, D. (2007) · IEEE Transactions on Biomedical Engineering · doi:10.1109/tbme.2007.908310 · Cited by 136
Cortical responses elicited by photovoltaic subretinal prostheses exhibit similarities to visually evoked potentials
Mandel, Y., Goetz, G. A., Lavinsky, D., Huie, P., Mathieson, K., Wang, L., Kamins, T. I., Galambos, L., Manivanh, R. V., Harris, J. S., et al. (2013) · Nature Communications · doi:10.1038/ncomms2980 · Cited by 131
Factors Affecting Perceptual Threshold in Argus II Retinal Prosthesis Subjects
Ahuja, A. K., Yeoh, J., Dorn, J. D., Caspi, A., Wuyyuru, V., McMahon, M. J., Humayun, M. S., Greenberg, R. J., daCruz, L., & Argus II Study Group (2013) · Translational Vision Science & Technology · doi:10.1167/tvst.2.4.1 · Cited by 127
Self-citation
Simulation of artificial vision: II. Eccentric reading of full-page text and the learning of this task
Sommerhalder, J., Rappaz, B., de Haller, R., Fornos, A. P., Safran, A. B., & Pelizzone, M. (2004) · Vision Research · doi:10.1016/j.visres.2004.01.017 · Cited by 116
Temporal properties of visual perception on electrical stimulation of the retina
Pérez Fornos, A., Sommerhalder, J., da Cruz, L., Sahel, J. A., Mohand-Said, S., Hafezi, F., & Pelizzone, M. (2012) · Investigative Opthalmology & Visual Science · doi:10.1167/iovs.11-9344 · Cited by 113
Simulation of artificial vision: I. Eccentric reading of isolated words, and perceptual learning
Sommerhalder, J., Oueghlani, E., Bagnoud, M., Leonards, U., Safran, A. B., & Pelizzone, M. (2003) · Vision Research · doi:10.1016/s0042-6989(02)00481-9 · Cited by 111
Predicting visual sensitivity in retinal prosthesis patients
Horsager, A., Greenwald, S. H., Weiland, J. D., Humayun, M. S., Greenberg, R. J., McMahon, M. J., Boynton, G. M., & Fine, I. (2009) · Investigative Opthalmology & Visual Science · doi:10.1167/iovs.08-2595 · Cited by 107
Effect of shape and coating of a subretinal prosthesis on its integration with the retina
Butterwick, A., Huie, P., Jones, B. W., Marc, R. E., Marmor, M. F., & Palanker, D. (2008) · Experimental Eye Research · doi:10.1016/j.exer.2008.09.018 · Cited by 107
Intraocular Retinal Prosthesis
Jaeger, D., & Jung, R. (2015) · Springer eBooks · doi:10.1007/978-1-4614-6675-8_100279 · Cited by 104
Differential responses to high-frequency electrical stimulation in ON and OFF retinal ganglion cells
Twyford, P., Cai, C., & Fried, S. I. (2014) · Journal of Neural Engineering · doi:10.1088/1741-2560/11/2/025001 · Cited by 103
Resolution of the epiretinal prosthesis is not limited by electrode size
Behrend, M. R., Ahuja, A. K., Humayun, M. S., Chow, R. H., & Weiland, J. D. (2011) · IEEE Transactions on Neural Systems and Rehabilitation Engineering · doi:10.1109/tnsre.2011.2140132 · Cited by 102
Learning to see again: biological constraints on cortical plasticity and the implications for sight restoration technologies
Beyeler, M., Rokem, A., Boynton, G. M., & Fine, I. (2017) · Journal of Neural Engineering · doi:10.1088/1741-2552/aa795e · Cited by 102
Preliminary 6 month results from the argustm ii epiretinal prosthesis feasibility study
Humayun, M. S., Dorn, J. D., Ahuja, A. K., Caspi, A., Filley, E., Dagnelie, G., Salzmann, J., Santos, A., Duncan, J., daCruz, L., et al. (2009) · 2009 Annual International Conference of the IEEE Engineering in Medicine and Biology Society · doi:10.1109/iembs.2009.5332695 · Cited by 100
The electrically evoked response of the visual system (EER).
Potts, A. M., Inoue, J., & Buffum, D. (1968) · PubMed · Cited by 98
Loss of Responses to Visual But Not Electrical Stimulation in Ganglion Cells of Rats With Severe Photoreceptor Degeneration
Sekirnjak, C., Hulse, C., Jepson, L. H., Hottowy, P., Sher, A., Dąbrowski, W., Litke, A. M., & Chichilnisky, E. J. (2009) · Journal of Neurophysiology · doi:10.1152/jn.00663.2009 · Cited by 98
Focal electrical stimulation of major ganglion cell types in the primate retina for the design of visual prostheses
Jepson, L. H., Hottowy, P., Mathieson, K., Gunning, D. E., Dąbrowski, W., Litke, A. M., & Chichilnisky, E. J. (2013) · The Journal of Neuroscience · doi:10.1523/jneurosci.4967-12.2013 · Cited by 97
Spatiotemporal Interactions in Retinal Prosthesis Subjects
Horsager, A., Greenberg, R. J., & Fine, I. (2010) · Investigative Opthalmology & Visual Science · doi:10.1167/iovs.09-3746 · Cited by 95
Pharmacological approaches to retinitis pigmentosa: A laboratory perspective
Guadagni, V., Novelli, E., Piano, I., Gargini, C., & Strettoi, E. (2015) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2015.06.005 · Cited by 94
Cortical Activation Via an Implanted Wireless Retinal Prosthesis
Walter, P., ́rday, Z. ́. F. K., Görtz, M., Alteheld, N., Rößler, G., Stieglitz, T., & Eysel, U. T. (2005) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.04-0924 · Cited by 93
Performance of real‐world functional vision tasks by blind subjects improves after implantation with the Argus® II retinal prosthesis system
Dagnelie, G., Christopher, P., Arditi, A. R., da Cruz, L., Duncan, J. L., Ho, A. C., de Koo, L. C. O., Sahel, J., Stanga, P. E., Thumann, G., et al. (2016) · Clinical and Experimental Ophthalmology · doi:10.1111/ceo.12812 · Cited by 93
Vitrectomy: a pars plana approach. Technical improvements and further results.
Machemer, R., PAREL, J. M., & NORTON, E. W. D. (1973) · PubMed · Cited by 91
Understanding the origin of visual percepts elicited by electrical stimulation of the human retina
Weiland, J. D., Humayun, M. S., Dagnelie, G., de Juan, E., Greenberg, R. J., & Iliff, N. T. (1999) · Graefe s Archive for Clinical and Experimental Ophthalmology · doi:10.1007/s004170050337 · Cited by 90
Paragraph Text Reading Using a Pixelized Prosthetic Vision Simulator: Parameter Dependence and Task Learning in Free-Viewing Conditions
Dagnelie, G., Barnett, D., Humayun, M. S., & Thompson, R. W. (2006) · Investigative Opthalmology & Visual Science · doi:10.1167/iovs.05-0157 · Cited by 90
The visual sensations produced by electrical stimulation of the medial occipital cortex.
Brindley, G. S., & Lewin, W. S. (1968) · PubMed · Cited by 89
Implantation and explantation of an active epiretinal visual prosthesis: 2-year follow-up data from the EPIRET3 prospective clinical trial
Menzel-Severing, J., Laube, T., Brockmann, C., Bornfeld, N., Mokwa, W., Mazinani, B. A. E., Walter, P., & Roessler, G. F. (2012) · Eye · doi:10.1038/eye.2012.35 · Cited by 83
The Argus II Retinal Prosthesis: 12-Month Outcomes from a Single-Study Center
Rizzo, S., Belting, C., Cinelli, L., Allegrini, L., Genovesi-Ebert, F., Barca, F., & Bartolo, E. D. (2014) · American Journal of Ophthalmology · doi:10.1016/j.ajo.2014.02.039 · Cited by 83
The Argus™ II retinal prosthesis: Factors affecting patient selection for implantation
Ahuja, A., & Behrend, M. R. (2013) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2013.01.002 · Cited by 82
Evoked cortical potentials after electrical stimulation of the inner retina in rabbits
Walter, P., & Heimann, K. (2000) · Graefe s Archive for Clinical and Experimental Ophthalmology · doi:10.1007/s004170050358 · Cited by 80
An analysis of observer-rated functional vision in patients implanted with the Argus II retinal prosthesis system at three years
Geruschat, D. R., Richards, T. P., Arditi, A., Cruz, L., Dagnelie, G., Dorn, J. D., Duncan, J. L., Ho, A. C., Olmos de koo, L. C., Sahel, J., et al. (2016) · Clinical and Experimental Optometry · doi:10.1111/cxo.12359 · Cited by 77
The electrically evoked response (EER) of the visual system. II. Effect of adaptation and retinitis pigmentosa.
Potts, A. M., & Inoue, J. (1969) · PubMed · Cited by 75
FLORA™: phase I development of a functional vision assessment for prosthetic vision users
Geruschat, D. R., Flax, M., Tanna, N., Bianchi, M., Fisher, A., Goldschmidt, M., Fisher, L., Dagnelie, G., Deremeik, J., Smith, A., et al. (2015) · Clinical and Experimental Optometry · doi:10.1111/cxo.12242 · Cited by 75
Retinal prosthesis phosphene shape analysis
Nanduri, D., Humayun, M. S., Greenberg, R. J., McMahon, M. J., & Weiland, J. D. (2008) · 2008 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society · doi:10.1109/iembs.2008.4649524 · Cited by 74
Pixium Vision: First Clinical Results and Innovative Developments
Hornig, R., Dapper, M., Joliff, E. L., Hill, R. G., Ishaque, K., Posch, C., Benosman, R. B., Mer, Y. L., Sahel, J., & Picaud, S. A. (2016) · Springer eBooks · doi:10.1007/978-3-319-41876-6_8 · Cited by 73
High-Fidelity Reproduction of Spatiotemporal Visual Signals for Retinal Prosthesis
Jepson, L. H., Hottowy, P., Weiner, G., Dąbrowski, W., Litke, A. M., & Chichilnisky, E. J. (2014) · Neuron · doi:10.1016/j.neuron.2014.04.044 · Cited by 71
Saliency-based image processing for retinal prostheses
Parikh, N., Itti, L., & Weiland, J. D. (2010) · Journal of Neural Engineering · doi:10.1088/1741-2560/7/1/016006 · Cited by 70
Long-term stimulation by active epiretinal implants in normal and RCD1 dogs
Güven, D., Weiland, J. D., Fujii, G. Y., Mech, B. V., Mahadevappa, M., Greenberg, R. J., Roizenblatt, R., Qiu, G., LABREE, L. D., Wang, X., et al. (2005) · Journal of Neural Engineering · doi:10.1088/1741-2560/2/1/009 · Cited by 70
Migration of Retinal Cells through a Perforated Membrane: Implications for a High-Resolution Prosthesis
Palanker, D., Huie, P., Vankov, A., Aramant, R. B., Seiler, M. J., Fishman, H. A., Marmor, M. F., & Blumenkranz, M. S. (2004) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.03-1327 · Cited by 69
Ten-Year Follow-up of a Blind Patient Chronically Implanted with Epiretinal Prosthesis Argus I
Lan, Y., Falabella, P., Christopher, P., Wuyyuru, V., Dorn, J. D., Schor, P., Greenberg, R. J., Weiland, J. D., & Humayun, M. S. (2015) · Ophthalmology · doi:10.1016/j.ophtha.2015.08.008 · Cited by 67
Development of a silicon retinal implant: cortical evoked potentials following focal stimulation of the rabbit retina with light and electricity
Nadig, M. N. (1999) · Clinical Neurophysiology · doi:10.1016/s1388-2457(99)00027-9 · Cited by 66
Consistent phosphenes generated by electrical microstimulation of the visual thalamus. An experimental approach for thalamic visual neuroprostheses
Panetsos, F., Sanchez-Jimenez, A., Cerio, E. D.-D., Diaz-Guemes, I., & Sanchez, F. M. (2011) · Frontiers in Neuroscience · doi:10.3389/fnins.2011.00084 · Cited by 65
The artificial silicon retina in retinitis pigmentosa patients (an American Ophthalmological Association thesis).
Chow, A. Y., Bittner, A. K., & Pardue, M. T. (2010) · PubMed Central · Cited by 60
Organic Electrodes and Communications with Excitable Cells
Harris, A. R., & Wallace, G. G. (2017) · Advanced Functional Materials · doi:10.1002/adfm.201700587 · Cited by 60
The electrically evoked response of the visual system (EER). 3. Further contribution to the origin of the EER.
Potts, A. M., & Inoue, J. (1970) · PubMed · Cited by 59
Simulating prosthetic vision: II. Measuring functional capacity
Chen, S. C., Suaning, G. J., Morley, J. W., & Lovell, N. H. (2009) · Vision Research · doi:10.1016/j.visres.2009.07.003 · Cited by 59
Artificial vision by direct optic nerve electrode (AV-DONE) implantation in a blind patient with retinitis pigmentosa
Sakaguchi, H., Kamei, M., Fujikado, T., Yonezawa, E., Ozawa, M., Cecilia-Gonzalez, C., Ustariz-Gonzalez, O., Quiroz-Mercado, H., & Tano, Y. (2009) · Journal of Artificial Organs · doi:10.1007/s10047-009-0467-2 · Cited by 58
Retinal Prosthetics, Optogenetics, and Chemical Photoswitches
Marc, R. E., Pfeiffer, R. L., & Jones, B. W. (2014) · ACS Chemical Neuroscience · doi:10.1021/cn5001233 · Cited by 56
Safety evaluation of “retina implant alpha IMS”—a prospective clinical trial
Kitiratschky, V. B. D., Štingl, K., Wilhelm, B., Peters, T. M., Besch, D., Sachs, H. G., Gekeler, F., Bartz‐Schmidt, K. U., & Zrenner, E. (2014) · Graefe s Archive for Clinical and Experimental Ophthalmology · doi:10.1007/s00417-014-2797-x · Cited by 55
Activation of retinal ganglion cells following epiretinal electrical stimulation with hexagonally arranged bipolar electrodes
Abramian, M., Lovell, N. H., Morley, J. W., Suaning, G. J., & Dokos, S. (2011) · Journal of Neural Engineering · doi:10.1088/1741-2560/8/3/035004 · Cited by 52
Simulation of artificial vision: IV. Visual information required to achieve simple pointing and manipulation tasks
Fornos, A. P., Sommerhalder, J., Pittard, A., Safran, A. B., & Pelizzone, M. (2008) · Vision Research · doi:10.1016/j.visres.2008.04.027 · Cited by 50
Artificial retina: the multichannel processing of the mammalian retina achieved with a neuromorphic asynchronous light acquisition device
Lorach, H., Benosman, R. B., Marre, O., Ieng, S.-H., Sahel, J., & Picaud, S. A. (2012) · Journal of Neural Engineering · doi:10.1088/1741-2560/9/6/066004 · Cited by 49
Safety and efficacy of subretinal visual implants in humans: methodological aspects
Štingl, K., Bach, M., Bartz‐Schmidt, K. U., Braun, A., Bruckmann, A. R., Gekeler, F., Greppmaier, U., Hörtdörfer, G., Kusnyerik, Á., Peters, T. M., et al. (2012) · Clinical and Experimental Optometry · doi:10.1111/j.1444-0938.2012.00816.x · Cited by 48
Temporal interactions during paired-electrode stimulation in two retinal prosthesis subjects
Horsager, A., Boynton, G. M., Greenberg, R. J., & Fine, I. (2011) · Investigative Opthalmology & Visual Science · doi:10.1167/iovs.10-5282 · Cited by 48
Importance of eye position on spatial localization in blind subjects wearing an Argus II retinal prosthesis
Sabbah, N., Authie, C. N., Sanda, N., Mohand-Said, S., Sahel, J.-A., & Safran, A. B. (2014) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.14-15392 · Cited by 45
The Argus II prosthesis facilitates reaching and grasping tasks: a case series
Kotecha, A., Zhong, J., Stewart, D., & da Cruz, L. (2014) · BMC Ophthalmology · doi:10.1186/1471-2415-14-71 · Cited by 42
Neural responses elicited by electrical stimulation of the retina.
Chen, S., Mahadevappa, M., Roizenblatt, R., Weiland, J. D., & Humayun, M. S. (2006) · Europe PMC (PubMed Central) · Cited by 41
The use of Argus® II retinal prosthesis by blind subjects to achieve localisation and prehension of objects in 3-dimensional space
Luo, Y. H.-L., Zhong, J., & da Cruz, L. (2014) · Graefe s Archive for Clinical and Experimental Ophthalmology · doi:10.1007/s00417-014-2912-z · Cited by 39
Self-citation
Assessment of MRI issues for the Argus II Retinal Prosthesis
Weiland, J. D., Faraji, B., Greenberg, R. J., Humayun, M. S., & Shellock, F. G. (2012) · Magnetic Resonance Imaging · doi:10.1016/j.mri.2011.12.005 · Cited by 38
Visual Prosthesis: The Interdisciplinary Dialogue.
Miller, D. (1972) · Archives of Ophthalmology · doi:10.1001/archopht.1972.01000030233025 · Cited by 37
Parylene origami structure for intraocular implantation
Liu, Y., Park, J., Lang, R. J., Emami, A., Pellegrino, S., Humayun, M. S., & Tai, Y. (2013) · International Conference on Solid-State Sensors, Actuators and Microsystems · doi:10.1109/transducers.2013.6627077 · Cited by 28
Electronic Approaches to Restitute Vision in Patients with Neurodegenerative Diseases of the Retina
Štingl, K., & Zrenner, E. (2013) · Ophthalmic Research · doi:10.1159/000354424 · Cited by 27
Preoperative Functional Assessment of Auditory Cortex in Adult Cochlear Implant Users
Roland, P. S., Tobey, E. A., & Devous, M. D. (2001) · The Laryngoscope · doi:10.1097/00005537-200101000-00013 · Cited by 24
Electrically Elicited Visual Evoked Potentials in Argus II Retinal Implant Wearers
Stronks, H. C., Barry, M. P., & Dagnelie, G. (2013) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.13-11594 · Cited by 24
Acuboost™: Enhancing the maximum acuity of the Argus II Retinal Prosthesis System
Sahel, J., Mohand‐Saïd, S., Stanga, P. E., Caspi, A., & Greenberg, R. J. (2013) · Investigative Ophthalmology & Visual Science · Cited by 23
AN INTRAOCULAR CAMERA FOR RETINAL PROSTHESES: RESTORING SIGHT TO THE BLIND
Stiles, N. R. B., McIntosh, B. P., Nasiatka, P. J., HAUER, M. C., Weiland, J. D., Humayun, M. S., & Tanguay, A. R. (2010) · Advanced series in applied physics · doi:10.1142/9789814295789_0020 · Cited by 18
Face Detection using the Argus® II Retinal Prosthesis System
Stanga, P. E., Sahel, J., Mohand‐Saïd, S., da Cruz, L., Caspi, A., Merlini, F., & Greenberg, R. J. (2013) · Investigative Ophthalmology & Visual Science · Cited by 17
Implanted Intraocular Retinal Prosthesis in Six Blind Subjects
Humayun, M. S., Freda, R., Fine, I., Roy, A., FUJII, G. Y., Greenberg, R. J., Little, J., Mech, B. V., Weiland, J. D., & de Juan, E. (2005) · Investigative Ophthalmology & Visual Science · Cited by 17
A fully intraocular 0.0169mm2/pixel 512-channel self-calibrating epiretinal prosthesis in 65nm CMOS
Monge, M., Raj, M., Nazari, M. H., Chang, H.-C., Zhao, Y., Weiland, J. D., Humayun, M. S., Tai, Y., & Emami, A. (2013) · Digest of technical papers/Digest of technical papers - IEEE International Solid-State Circuits Conference · doi:10.1109/isscc.2013.6487742 · Cited by 16
Virtual Wayfinding Using Simulated Prosthetic Vision in Gaze‐locked Viewing
Wang, L., Yang, L., & Dagnelie, G. (2008) · Optometry and Vision Science · doi:10.1097/opx.0b013e31818b9f36 · Cited by 16
Selective activation of ON and OFF retinal ganglion cells to high-frequency electrical stimulation: A computational modeling study
Guo, T., Lovell, N. H., Tsai, D., Twyford, P., Fried, S. I., Morley, J. W., Suaning, G. J., & Dokos, S. (2014) · Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) · doi:10.1109/embc.2014.6945023 · Cited by 16
A Retinal Neuroprosthesis Design Based on Simultaneous Current Injection
Lovell, N. H., Dokos, S., Preston, P., Lehmann, T., Dommel, N., Lin, A., Wong, Y. T., Opie, N. L., Hallum, L. E., Chen, S. C., et al. (2005) · International IEEE-EMBS Special Topic Conference on Microtechnologies in Medicine and Biology (MMB) · doi:10.1109/mmb.2005.1548394 · Cited by 16
Implantation of a newly developed direct optic nerve electrode device for artificial vision in rabbits
Sakaguchi, H., Kamei, M., Nishida, K., Terasawa, Y., Fujikado, T., Ozawa, M., & Nishida, K. (2012) · Journal of Artificial Organs · doi:10.1007/s10047-012-0642-8 · Cited by 14
MRI Brain Scans in Two Patients with the Argus II Retinal Prosthesis
Luo, Y. H.-L., Davagnanam, I., & daCruz, L. (2013) · Ophthalmology · doi:10.1016/j.ophtha.2013.04.021 · Cited by 14
Self-citation
Prosthetic vision in blind human patients: Predicting the percepts of epiretinal stimulation
Nanduri, D. (2015) · University of Southern California Digital Library · doi:10.25549/usctheses-c3-196626 · Cited by 13
High Resolution Photovoltaic Subretinal Prosthesis for Restoration of Sight
Lorach, H., & Palanker, D. (2016) · Springer eBooks · doi:10.1007/978-3-319-41876-6_9 · Cited by 13
First experience with The IRIS retinal implant system
Velikay‐Parel, M., Ivastinović, D., Langmann, G., Hornig, R., GEORGI, T., & Wedrich, A. (2009) · Acta Ophthalmologica · doi:10.1111/j.1755-3768.2009.3115.x · Cited by 12
Prospects and Limitations of Spatial Resolution
Sommerhalder, J., & Fornos, A. P. (2016) · Springer eBooks · doi:10.1007/978-3-319-41876-6_4 · Cited by 11
A Fully Intraocular Approach for a Bi-Directional Retinal Prosthesis
Walter, P. (2016) · Springer eBooks · doi:10.1007/978-3-319-41876-6_12 · Cited by 10
Intraocular Retinal Prosthesis
Jaeger, D., & Jung, R. (2022) · Encyclopedia of Computational Neuroscience · doi:10.1007/978-1-0716-1006-0_300297 · Cited by 10
Optical Coherence Tomography‐Guided Retinal Prosthesis Design: Model of Degenerated Retinal Curvature and Thickness for Patient‐Specific Devices
Opie, N. L., Ayton, L. N., Apollo, N. V., Ganesan, K., Guymer, R. H., & Luu, C. D. (2014) · Artificial Organs · doi:10.1111/aor.12287 · Cited by 9
Embedded device for simultaneous recording and stimulation for retina implant research
Schloesser, M., Cota, O. F., Heil, R., Brusius, J. S., Offenhäusser, A., van Waasen, S., & Schiek, M. (2013) · Proceedings of IEEE Sensors/Proceedings of IEEE Sensors ... · doi:10.1109/icsens.2013.6688173 · Cited by 9
A test method for quantification of stimulus-induced depression effects on perceptual threshold in epiretinal prosthesis
Velikay‐Parel, M., Ivastinović, D., Georgi, T., Richard, G. W., & Hornig, R. (2013) · Acta Ophthalmologica · doi:10.1111/aos.12179 · Cited by 9
Thalamic visual neuroprostheses: Comparison of visual percepts generated by natural stimulation of the eye and electrical stimulation of the thalamus
Panetsos, F., Rodrigo-Diaz, E., Sánchez‐Jiménez, A., & Herrera‐Rincon, C. (2009) · International IEEE/EMBS Conference on Neural Engineering · doi:10.1109/ner.2009.5109233 · Cited by 9
Subjects Blinded By Outer Retinal Dystrophies Are Able To Recognize Shapes Using The Argus II Retinal Prosthesis System
Arsiero, M., da Cruz, L., Merlini, F., Sahel, J., Stanga, P. E., Hafezi, F., & Greenberg, R. J. (2011) · Investigative Ophthalmology & Visual Science · Cited by 9
Efficacy and reliability of long-term implantation of multi-channel microelectrode arrays in the optical nerve sheath of rabbit eyes
Wang, K., Li, X., Li, X., Pei, W., Chen, H., & Dong, J. (2011) · Vision Research · doi:10.1016/j.visres.2011.06.019 · Cited by 8
A fully intraocular 0.0169 mm^2/pixel 512-channel self-calibrating epiretinal prosthesis in 65nm CMOS
Monge, M., Raj, M., Honarvar-Nazari, M., Chang, H.-C., Zhao, Y., Weiland, J., Humayun, M., Tai, Y.-C., & Emami, A. (2013) · CaltechAUTHORS (California Institute of Technology) · Cited by 8
Inter-electrode Discriminability Correlates With Spatial Visual Performance In ArgusTM II Subjects
Lauritzen, T. Z., Nanduri, D., Weiland, J., Dorn, J. D., McClure, K., & Greenberg, R. J. (2011) · Investigative Ophthalmology & Visual Science · Cited by 7
Neural networks for braille reading by the blind include visual cortex
Sadato, N., Yonekura, Y., Ishii, Y., Deiber, M., Ibanez, V., & Hallett, M. (1996) · NeuroImage · doi:10.1016/s1053-8119(96)80342-9 · Cited by 7
Delivery of Information and Power to the Implant, Integration of the Electrode Array with the Retina, and Safety of Chronic Stimulation
Loudin, J., Butterwick, A. F., Huie, P., & Palanker, D. (2011) · Springer eBooks · doi:10.1007/978-1-4419-0754-7_7 · Cited by 5
Visual Perception in Blind Subjects with Microelectronic Retinal Prosthesis
Yanai, D., Weiland, J. D., Mahadevappa, M., FUJII, G. Y., de Juan, E., Greenberg, R. J., Williamson, R. C., Cimmarusti, V., & Humayun, M. S. (2003) · Investigative Ophthalmology & Visual Science · Cited by 5
Edge-preserving image decomposition based on saliency map
Feng, C., Dai, S., Zhao, Y., & Liu, S. (2014) · International Congress on Image and Signal Processing (CISP) · doi:10.1109/cisp.2014.7003769 · Cited by 5
Activation of ganglion cell axons following epiretinal electrical stimulation with hexagonal electrodes
Abramian, M., Dokos, S., Morley, J. W., & Lovell, N. H. (2010) · Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) · doi:10.1109/iembs.2010.5626002 · Cited by 5
Design considerations for high-density fully intraocular epiretinal prostheses
Monge, M., & Emami, A. (2014) · IEEE Biomedical Circuits and Systems Conference (BioCAS) · doi:10.1109/biocas.2014.6981703 · Cited by 4
Charge recovery during concurrent stimulation for a vision prosthesis
Addi, M. M., Dokos, S., Preston, P., Dommel, N., Wong, Y. T., & Lovell, N. H. (2008) · Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) · doi:10.1109/iembs.2008.4649527 · Cited by 4
Modeling the Effect of Fixational Eye Movements in Natural Scenes
Olmedo-Payá, A., Martínez-Álvarez, A., Cuenca-Asensi, S., Vicente, J. M. F., & Fernández, E. (2013) · Lecture notes in computer science · doi:10.1007/978-3-642-38637-4_34 · Cited by 3
The scleral buckling procedure.
Friedman, M. W. (1958) · PubMed · Cited by 3
Introduction to Visual Prostheses -- Webvision: The Organization of the Retina and Visual System
Kolb, H., Fernández, E., & Nelson, R. (1995) · Cited by 3
Intraocular camera for retinal prostheses: refractive and diffractive lens systems
Hauer, M. C. (. (2012) · doi:10.25549/usctheses-m1971 · Cited by 3
Simulation of visual prosthesis in virtual space
Terasawa, Y., Fujikado, T., & Yagi, T. (2001) · International Journal of Applied Electromagnetics and Mechanics · doi:10.3233/jae-2002-484 · Cited by 2
Thresholds for Direct and Indirect Activation of Ganglion Cells With an Epiretinal Electrode: Effect of Stimulus Duration and Electrode Size
Jensen, R. J., Ziv, O. R., & Rizzo, J. F. (2003) · Investigative Ophthalmology & Visual Science · Cited by 2
Cross-modal plasticity: Lessons from the visual system
Ptito, M. (2010) · Journal of Vision · doi:10.1167/6.13.11 · Cited by 2
In vivo performance of photovoltaic subretinal prosthesis
Mandel, Y., Goetz, G., Lavinsky, D., Huie, P., Mathieson, K., Wang, L., Kamins, T. I., Manivanh, R. V., Harris, J. S., & Palanker, D. (2013) · Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE · doi:10.1117/12.2001750 · Cited by 2

Flagged first, then by citations

7 of the 189 references couldn’t be matched to a known paper.

Research works printed but not linked: 5

Brindley, 1964, The number of information channels needed for efficient reading, J. Physiol., 44
Dagnelie, 2014, (16:30) Electrically elicited ERGs and VEPs in Argus II recipients: a window into signal processing in the degenerated RP retina, Doc. Ophthalmol., 1, 34
Foerster, 1929, Beiträge zur Pathophysiologie der Sehbahn und der Sehsphäre, J. Psychol. Neurol., 463
Milam, 1998, Histopathology of the human retina in retinitis pigmentosa, Prog. Retin. Eye Res., 17, 175
OECD, 2012. Magnetic resonance imaging (MRI) exams, total 2012/2. oecd-ilibrary.org. http://dx.doi.org/10.1787/mri-exam-total-table-2012-2-en. · DOI

Sorted by citations

Molecular genetics and emerging therapies for retinitis pigmentosa: Basic research and clinical perspectives
Dias, M. F., Joo, K., Kemp, J. A., Fialho, S. L., Silva‐Cunha, A., Woo, S. J., & Kwon, Y. J. (2017) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2017.10.004 · Cited by 437
Retinal stimulation strategies to restore vision: fundamentals and systems
Yue, L., Weiland, J. D., Roska, B., & Humayun, M. S. (2016) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2016.05.002 · Cited by 272
Photovoltaic Restoration of Central Vision in Atrophic Age-Related Macular Degeneration
Palanker, D., Le Mer, Y., Mohand-Said, S., Muqit, M., & Sahel, J. A. (2020) · Ophthalmology · doi:10.1016/j.ophtha.2020.02.024 · Cited by 227
Stemming retinal regeneration with pluripotent stem cells
Jin, Z., Gao, M.-L., Deng, W.-L., Wu, K., Sugita, S., Mandai, M., & Takahashi, M. (2018) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2018.11.003 · Cited by 221
Advances in retinal prosthesis systems
Bloch, E., Luo, Y., & da Cruz, L. (2019) · Therapeutic Advances in Ophthalmology · doi:10.1177/2515841418817501 · Cited by 201

See all 355

Authors: Luo, Y. H.-L., & da Cruz, L.
Affiliations: Moorfields Eye Hospital NHS Foundation Trust (GB)
ORCID: Luo, Yvonne Hsu-Lin
Venue: Progress in Retinal and Eye Research
Publisher: Elsevier BV
Published: 2016-01
Volume: 50
Pages: 89-107
ISSN: 1350-9462 (ISSN-L)
DOI: 10.1016/j.preteyeres.2015.09.003
OpenAlex: W1778783464
Cited by: 351
References: 189
Citations by year: 2026: 21 · 2025: 36 · 2024: 32 · 2023: 36 · 2022: 38 · 2021: 43 · 2020: 37 · 2019: 36 · 2018: 33 · 2017: 24 · 2016: 14
FWCI: 2.82
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Progress in Retinal and Eye Research (publishedVersion)
PubMed (publishedVersion)
Topics: Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neural Engineering
Health Sciences › Medicine › Ophthalmology › Retinal Development and Disorders
Life Sciences › Neuroscience › Cognitive Neuroscience › Tactile and Sensory Interactions
Keywords: Argus II, retinal prosthesis, retinitis pigmentosa, photoreceptor degeneration, vision loss, visual prosthesis, orientation and mobility, visual function outcomes, device safety, animal studies, clinical trials
MeSH terms: Animals, Blindness, Electrodes, Implanted, Electric Stimulation Therapy, Humans, Prosthesis Design, Retinal Diseases, Visual Acuity, Visual Perception, Visual Prosthesis, Implantable Neurostimulators

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

The Argus® II Retinal Prosthesis System

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks