The amygdala, reward and emotion

Murray, Elisabeth A.

doi:10.1016/j.tics.2007.08.013

Cited by 679Memory and Neural MechanismsNeural and Behavioral Psychology StudiesNeurotransmitter Receptor Influence on Behavior

The amygdala, reward and emotion

Murray, Elisabeth A.·2007·Trends in Cognitive Sciences

DOI 10.1016/j.tics.2007.08.013

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Abstract

Recent research provides new insights into amygdala contributions to positive emotion and reward. Studies of neuronal activity in the monkey amygdala and of autonomic responses mediated by the monkey amygdala show that, contrary to a widely held view, the amygdala is just as important for processing positive reward and reinforcement as it is for negative. In addition, neuropsychological studies reveal that the amygdala is essential for only a fraction of what might be considered 'stimulus-reward processing', and that the neural substrates for emotion and reward are partially nonoverlapping. Finally, evidence suggests that two systems within the amygdala, operating in parallel, enable reward-predicting cues to influence behavior; one mediates a general, arousing effect of reward and the other links the sensory properties of reward to emotion.

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Other neural pathways and brain structures, e.g., the amygdala and limbic regions, have been shown to be involved in processing of rewards and socio-emotional stimuli.
“Besides the cortical and subcortical systems responsible for attentional and cognitive processes, other neural pathways and brains structures, e.g., the amygdala and limbic regions, have been shown to be involved in processing of rewards and socio-emotional stimuli (Murray, 2007).”
From Is autonomic nervous system function atypical in Attention Deficit Hyperactivity Disorder (ADHD)? A systematic review of the evidence (2020) · cites this paper as Murray, 2007
Emotion plays a role in decision-making.
“It is widely acknowledged that emotion plays a role in decision-making, drawing on evidence from numerous behavioral studies using emotional stimuli as well as physiological, neuroimaging, and lesion studies.”
From Thinking like a trader selectively reduces individuals' loss aversion (2009) · cites this paper as [12]

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“Amygdala function in positive affect The idea that the amygdala functions primarily in negative affect remains firmly entrenched, as evidenced by theories treating the amygdala as a ‘protection device’ that prevents animals from engaging in potentially harmful behaviors [16] or as a ‘fear module’ [ 17 ].”
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Authors: Murray, E. A.
Affiliations: National Institutes of Health (US)
Corresponding author: Murray, Elisabeth A.
ORCID: Murray, Elisabeth A.
Venue: Trends in Cognitive Sciences
Publisher: Elsevier BV
Published: 2007-11
Volume: 11
Issue: 11
Pages: 489-497
ISSN: 1364-6613 (ISSN-L)
DOI: 10.1016/j.tics.2007.08.013
OpenAlex: W2148301354
Cited by: 679
References: 87
Citations by year: 2026: 17 · 2025: 21 · 2024: 33 · 2023: 41 · 2022: 36 · 2021: 38 · 2020: 34 · 2019: 24 · 2018: 35 · 2017: 40 · 2016: 38 · 2015: 46 · 2014: 51 · 2013: 47 · 2012: 55
FWCI: 1.79
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Trends in Cognitive Sciences (publishedVersion)
PubMed (publishedVersion)
Topics: Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
Keywords: amygdala, reward processing, positive emotions, reinforcement, neural substrates of emotion, arousal, neuropsychology of emotion
MeSH terms: Affect, Amygdala, Animals, Haplorhini, Cognition, Emotions, Humans, Reward, Rats

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