Biological applications of magnetic nanoparticles

Self-Assembled Monolayers of Thiolates on Metals as a Form of Nanotechnology

Love, J. C., Estroff, L. A., Kriebel, J. K., Nuzzo, R. G., & Whitesides, G. M. (2005) · Chemical Reviews · doi:10.1021/cr0300789 · Cited by 8,282

Intrinsic peroxidase-like activity of ferromagnetic nanoparticles

Gao, L., Zhuang, J., Nie, L., Zhang, J., Zhang, Y., Gu, N., Wang, T., Feng, J., Yang, D., Perrett, S., et al. (2007) · Nature Nanotechnology · doi:10.1038/nnano.2007.260 · Cited by 7,483

Understanding biophysicochemical interactions at the nano–bio interface

Nel, A. E., Mädler, L., Velegol, D., Xia, T., Hoek, E. M. V., Somasundaran, P., Klaessig, F., Castranova, V., & Thompson, M. (2009) · Nature Materials · doi:10.1038/nmat2442 · Cited by 7,083

Synthesis and surface engineering of iron oxide nanoparticles for biomedical applications

Gupta, A. K., & Gupta, M. (2005) · Biomaterials · doi:10.1016/j.biomaterials.2004.10.012 · Cited by 6,771

Quantum dot bioconjugates for imaging, labelling and sensing

Medintz, I. L., Uyeda, H. T., Goldman, E. R., & Mattoussi, H. (2005) · Nature Materials · doi:10.1038/nmat1390 · Cited by 6,229

Determining the Size and Shape Dependence of Gold Nanoparticle Uptake into Mammalian Cells

Chithrani, B. D., Ghazani, A. A., & Chan, W. C. W. (2006) · Nano Letters · doi:10.1021/nl052396o · Cited by 4,879

Renal clearance of quantum dots

Soo Choi, H., Liu, W., Misra, P., Tanaka, E., Zimmer, J. P., Itty Ipe, B., Bawendi, M. G., & Frangioni, J. V. (2007) · Nature Biotechnology · doi:10.1038/nbt1340 · Cited by 4,476

Ultra-large-scale syntheses of monodisperse nanocrystals

Park, J., An, K., Hwang, Y., Park, J.-G., Noh, H.-J., Kim, J.-Y., Park, J.-H., Hwang, N.-M., & Hyeon, T. (2004) · Nature Materials · doi:10.1038/nmat1251 · Cited by 4,076

Monodisperse MFe2O4 (M = Fe, Co, Mn) Nanoparticles

Sun, S., Zeng, H., Robinson, D. B., Raoux, S., Rice, P. M., Wang, S. X., & Li, G. (2004) · Journal of the American Chemical Society · doi:10.1021/ja0380852 · Cited by 3,441

Probing the Cytotoxicity of Semiconductor Quantum Dots

Derfus, A. M., Chan, W. C. W., & Bhatia, S. N. (2004) · Nano Letters · doi:10.1021/nl0347334 · Cited by 3,391

Understanding the nanoparticle–protein corona using methods to quantify exchange rates and affinities of proteins for nanoparticles

Cedervall, T., Lynch, I., Lindman, S., Berggård, T., Thulin, E., Nilsson, H., Dawson, K. A., & Linse, S. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0608582104 · Cited by 3,281

The effect of particle design on cellular internalization pathways

Gratton, S. E. A., Ropp, P. A., Pohlhaus, P. D., Luft, J. C., Madden, V. J., Napier, M. E., & DeSimone, J. M. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0801763105 · Cited by 2,918

Preparation of aqueous magnetic liquids in alkaline and acidic media

Massart, R. (1981) · IEEE Transactions on Magnetics · doi:10.1109/tmag.1981.1061188 · Cited by 2,817

Magnetic nanoparticles in MR imaging and drug delivery

Sun, C., Lee, J. S. H., & Zhang, M. (2008) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2008.03.018 · Cited by 2,594

Heating magnetic fluid with alternating magnetic field

Rosensweig, R. E. (2002) · Journal of Magnetism and Magnetic Materials · doi:10.1016/s0304-8853(02)00706-0 · Cited by 2,551

Gold Nanoparticles for Biology and Medicine

Giljohann, D. A., Seferos, D. S., Daniel, W. L., Massich, M. D., Patel, P. C., & Mirkin, C. A. (2010) · Angewandte Chemie International Edition · doi:10.1002/anie.200904359 · Cited by 2,356

Synthesis of Highly Crystalline and Monodisperse Maghemite Nanocrystallites without a Size-Selection Process

Hyeon, T., Lee, S. S., Park, J., Chung, Y., & Na, H. B. (2001) · Journal of the American Chemical Society · doi:10.1021/ja016812s · Cited by 2,040

Hyperthermia in combined treatment of cancer

Wust, P., Hildebrandt, B., Sreenivasa, G., Rau, B., Gellermann, J., Riess, H., Felix, R., & Schlag, P. (2002) · The Lancet Oncology · doi:10.1016/s1470-2045(02)00818-5 · Cited by 1,998

Multifunctional Magnetic Nanoparticles: Design, Synthesis, and Biomedical Applications

Gao, J., Gu, H., & Xu, B. (2009) · Accounts of Chemical Research · doi:10.1021/ar9000026 · Cited by 1,907

Design and fabrication of magnetic nanoparticles for targeted drug delivery and imaging

Veiseh, O., Gunn, J. W., & Zhang, M. (2010) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2009.11.002 · Cited by 1,832

Biological applications of gold nanoparticles

Sperling, R. A., Rivera Gil, P., Zhang, F., Zanella, M., & Parak, W. J. (2008) · Chemical Society Reviews · doi:10.1039/b712170a · Cited by 1,799

Magnetic nanoparticle design for medical diagnosis and therapy

Mornet, S., Vasseur, S., Grasset, F., & Duguet, E. (2004) · Journal of Materials Chemistry · doi:10.1039/b402025a · Cited by 1,745

The cellular and molecular basis of hyperthermia

Hildebrandt, B. (2002) · Critical Reviews in Oncology/Hematology · doi:10.1016/s1040-8428(01)00179-2 · Cited by 1,718

Tat peptide-derivatized magnetic nanoparticles allow in vivo tracking and recovery of progenitor cells

Lewin, M., Carlesso, N., Tung, C.-H., Tang, X.-W., Cory, D., Scadden, D. T., & Weissleder, R. (2000) · Nature Biotechnology · doi:10.1038/74464 · Cited by 1,716

Molecular Rulers for Scaling Down Nanostructures

Hatzor, A., & Weiss, P. S. (2001) · Science · doi:10.1126/science.1057553 · Cited by 1,681

Targeted nanoparticle-aptamer bioconjugates for cancer chemotherapy in vivo

Farokhzad, O. C., Cheng, J., Teply, B. A., Sherifi, I., Jon, S., Kantoff, P. W., Richie, J. P., & Langer, R. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0601755103 · Cited by 1,663

Surface modification, functionalization and bioconjugation of colloidal inorganic nanoparticles

Sperling, R. A., & Parak, W. J. (2010) · Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences · doi:10.1098/rsta.2009.0273 · Cited by 1,601

PEGylated nanoparticles for biological and pharmaceutical applications

Otsuka, H., Nagasaki, Y., & Kataoka, K. (2003) · Advanced Drug Delivery Reviews · doi:10.1016/s0169-409x(02)00226-0 · Cited by 1,588

Efficacy and safety of intratumoral thermotherapy using magnetic iron-oxide nanoparticles combined with external beam radiotherapy on patients with recurrent glioblastoma multiforme

Maier-Hauff, K., Ulrich, F., Nestler, D., Niehoff, H., Wust, P., Thiesen, B., Orawa, H., Budach, V., & Jordan, A. (2011) · Journal of Neuro-Oncology · doi:10.1007/s11060-010-0389-0 · Cited by 1,429

Synthesis, Functionalization, and Biomedical Applications of Multifunctional Magnetic Nanoparticles

Hao, R., Xing, R., Xu, Z., Hou, Y., Gao, S., & Sun, S. (2010) · Advanced Materials · doi:10.1002/adma.201000260 · Cited by 1,372

Exchange-coupled magnetic nanoparticles for efficient heat induction

Lee, J.-H., Jang, J.-T., Choi, J.-S., Moon, S. H., Noh, S.-H., Kim, J.-W., Kim, J.-G., Kim, I.-S., Park, K. I., & Cheon, J. (2011) · Nature Nanotechnology · doi:10.1038/nnano.2011.95 · Cited by 1,364

Molecular Imaging

Weissleder, R., & Mahmood, U. (2001) · Radiology · doi:10.1148/radiology.219.2.r01ma19316 · Cited by 1,315

Multifunctional Uniform Nanoparticles Composed of a Magnetite Nanocrystal Core and a Mesoporous Silica Shell for Magnetic Resonance and Fluorescence Imaging and for Drug Delivery

Kim, J., Kim, H. S., Lee, N., Kim, T., Kim, H., Yu, T., Song, I. C., Moon, W. K., & Hyeon, T. (2008) · Angewandte Chemie International Edition · doi:10.1002/anie.200802469 · Cited by 1,220

Nanoscale Size Effect of Magnetic Nanocrystals and Their Utilization for Cancer Diagnosis via Magnetic Resonance Imaging

Jun, Y.-W., Huh, Y.-M., Choi, J.-S., Lee, J.-H., Song, H.-T., Kim, S., Yoon, S., Kim, K.-S., Shin, J.-S., Suh, J.-S., et al. (2005) · Journal of the American Chemical Society · doi:10.1021/ja0422155 · Cited by 1,193

NanoGenotoxicology: The DNA damaging potential of engineered nanomaterials

Singh, N., Manshian, B., Jenkins, G. J. S., Griffiths, S. M., Williams, P. M., Maffeis, T. G. G., Wright, C. J., & Doak, S. H. (2009) · Biomaterials · doi:10.1016/j.biomaterials.2009.04.009 · Cited by 1,184

Antibody Targeting of Long-Circulating Lipidic Nanoparticles Does Not Increase Tumor Localization but Does Increase Internalization in Animal Models

Kirpotin, D. B., Drummond, D. C., Shao, Y., Shalaby, M. R., Hong, K., Nielsen, U. B., Marks, J. D., Benz, C. C., & Park, J. W. (2006) · Cancer Research · doi:10.1158/0008-5472.can-05-4199 · Cited by 1,125

Autologous mesenchymal stem cell transplantation in stroke patients

Bang, O. Y., Lee, J. S., Lee, P. H., & Lee, G. (2005) · Annals of Neurology · doi:10.1002/ana.20501 · Cited by 1,102

Cardiac repair with intramyocardial injection of allogeneic mesenchymal stem cells after myocardial infarction

Amado, L. C., Saliaris, A. P., Schuleri, K. H., St. John, M., Xie, J.-S., Cattaneo, S., Durand, D. J., Fitton, T., Kuang, J. Q., Stewart, G., et al. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0504388102 · Cited by 1,073

Hydrophobic Nanocrystals Coated with an Amphiphilic Polymer Shell: A General Route to Water Soluble Nanocrystals

Pellegrino, T., Manna, L., Kudera, S., Liedl, T., Koktysh, D., Rogach, A. L., Keller, S., Rädler, J., Natile, G., & Parak, W. J. (2004) · Nano Letters · doi:10.1021/nl035172j · Cited by 1,067

Superparamagnetic iron oxide: pharmacokinetics and toxicity

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Size-Sorted Anionic Iron Oxide Nanomagnets as Colloidal Mediators for Magnetic Hyperthermia

Fortin, J.-P., Wilhelm, C., Servais, J., Ménager, C., Bacri, J.-C., & Gazeau, F. (2007) · Journal of the American Chemical Society · doi:10.1021/ja067457e · Cited by 1,038

Nanomedicine(s) under the Microscope

Duncan, R., & Gaspar, R. (2011) · Molecular Pharmaceutics · doi:10.1021/mp200394t · Cited by 981

Magnetofection: enhancing and targeting gene delivery by magnetic force in vitro and in vivo

Scherer, F., Anton, M., Schillinger, U., Henke, J., Bergemann, C., Krüger, A., Gänsbacher, B., & Plank, C. (2002) · Gene Therapy · doi:10.1038/sj.gt.3301624 · Cited by 932

Magnetic relaxation switches capable of sensing molecular interactions

Perez, J. M., Josephson, L., O'Loughlin, T., Högemann, D., & Weissleder, R. (2002) · Nature Biotechnology · doi:10.1038/nbt720 · Cited by 889

Magnetic nanoparticles for drug delivery

Dobson, J. (2006) · Drug Development Research · doi:10.1002/ddr.20067 · Cited by 886

High-Efficiency Intracellular Magnetic Labeling with Novel Superparamagnetic-Tat Peptide Conjugates

Josephson, L., Tung, C.-H., Moore, A., & Weissleder, R. (1999) · Bioconjugate Chemistry · doi:10.1021/bc980125h · Cited by 882

Regulation of Dendritic Cell Migration to the Draining Lymph Node

Martín-Fontecha, A., Sebastiani, S., Höpken, U. E., Uguccioni, M., Lipp, M., Lanzavecchia, A., & Sallusto, F. (2003) · The Journal of Experimental Medicine · doi:10.1084/jem.20030448 · Cited by 878

Nanoscaling Laws of Magnetic Nanoparticles and Their Applicabilities in Biomedical Sciences

Jun, Y.-W., Seo, J.-W., & Cheon, J. (2008) · Accounts of Chemical Research · doi:10.1021/ar700121f · Cited by 872

Size- and Shape-Controlled Magnetic (Cr, Mn, Fe, Co, Ni) Oxide Nanocrystals via a Simple and General Approach

Jana, N. R., Chen, Y., & Peng, X. (2004) · Chemistry of Materials · doi:10.1021/cm049221k · Cited by 870

Translating Stem and Progenitor Cell Biology to the Clinic: Barriers and Opportunities

Weissman, I. L. (2000) · Science · doi:10.1126/science.287.5457.1442 · Cited by 852

Magnetic resonance tracking of dendritic cells in melanoma patients for monitoring of cellular therapy

de Vries, I. J. M., Lesterhuis, W. J., Barentsz, J. O., Verdijk, P., van Krieken, J. H., Boerman, O. C., Oyen, W. J. G., Bonenkamp, J. J., Boezeman, J. B., Adema, G. J., et al. (2005) · Nature Biotechnology · doi:10.1038/nbt1154 · Cited by 821

Biomedical Nanomagnetics: A Spin Through Possibilities in Imaging, Diagnostics, and Therapy

Krishnan, K. M. (2010) · IEEE Transactions on Magnetics · doi:10.1109/tmag.2010.2046907 · Cited by 819

Clinical hyperthermia of prostate cancer using magnetic nanoparticles: Presentation of a new interstitial technique

Johannsen, M., Gneveckow, U., Eckelt, L., Feussner, A., WaldÖFner, N., Scholz, R., Deger, S., Wust, P., Loening, S. A., & Jordan, A. (2005) · International Journal of Hyperthermia · doi:10.1080/02656730500158360 · Cited by 798

Detailed Identification of Plasma Proteins Adsorbed on Copolymer Nanoparticles

Cedervall, T., Lynch, I., Foy, M., Berggård, T., Donnelly, S. C., Cagney, G., Linse, S., & Dawson, K. A. (2007) · Angewandte Chemie International Edition · doi:10.1002/anie.200700465 · Cited by 777

Targeted pharmaceutical nanocarriers for cancer therapy and imaging

Torchilin, V. P. (2007) · The AAPS Journal · doi:10.1208/aapsj0902015 · Cited by 762

Magnetic nanoparticles for gene and drug delivery

Dobson (2008) · International Journal of Nanomedicine · doi:10.2147/ijn.s1608 · Cited by 755

Design considerations for tumour-targeted nanoparticles

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A New Nonhydrolytic Single-Precursor Approach to Surfactant-Capped Nanocrystals of Transition Metal Oxides

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Precise engineering of targeted nanoparticles by using self-assembled biointegrated block copolymers

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Biofunctional magnetic nanoparticles for protein separation and pathogen detection

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In Vivo Magnetic Resonance Imaging of Mesenchymal Stem Cells in Myocardial Infarction

Kraitchman, D. L., Heldman, A. W., Atalar, E., Amado, L. C., Martin, B. J., Pittenger, M. F., Hare, J. M., & Bulte, J. W. M. (2003) · Circulation · doi:10.1161/01.cir.0000070931.62772.4e · Cited by 710

Monitoring of implanted stem cell migration in vivo : A highly resolved in vivo magnetic resonance imaging investigation of experimental stroke in rat

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Cellular toxicity of inorganic nanoparticles: Common aspects and guidelines for improved nanotoxicity evaluation

Soenen, S. J., Rivera-Gil, P., Montenegro, J.-M., Parak, W. J., De Smedt, S. C., & Braeckmans, K. (2011) · Nano Today · doi:10.1016/j.nantod.2011.08.001 · Cited by 699

Inductive heating of ferrimagnetic particles and magnetic fluids: Physical evaluation of their potential for hyperthermia

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Mesenchymal stem cell injection after myocardial infarction improves myocardial compliance

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Controlled PEGylation of Monodisperse Fe3O4 Nanoparticles for Reduced Non‐Specific Uptake by Macrophage Cells

Xie, J., Xu, C., Kohler, N., Hou, Y., & Sun, S. (2007) · Advanced Materials · doi:10.1002/adma.200701975 · Cited by 686

Intracellular uptake of anionic superparamagnetic nanoparticles as a function of their surface coating

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The use of gold nanoparticles in diagnostics and detection

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Detailed Identification of Plasma Proteins Adsorbed on Copolymer Nanoparticles

Cedervall, T., Lynch, I., Foy, M., Berggård, T., Donnelly, S. C., Cagney, G., Linse, S., & Dawson, K. A. (2007) · Angewandte Chemie · doi:10.1002/ange.200700465 · Cited by 655

Dextran-coated iron oxide nanoparticles: a versatile platform for targeted molecular imaging, molecular diagnostics, and therapy

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Magnetic nanoparticles and targeted drug delivering

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Hyperthermia in oncology

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Surface and Internal Spin Canting in γ-Fe2O3 Nanoparticles

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Chip–NMR biosensor for detection and molecular analysis of cells

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Biofunctionalized magnetic-vortex microdiscs for targeted cancer-cell destruction

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DC-based cancer vaccines

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Cytotoxicity suppression and cellular uptake enhancement of surface modified magnetic nanoparticles

Gupta, A. K., & Gupta, M. (2005) · Biomaterials · doi:10.1016/j.biomaterials.2004.05.022 · Cited by 586

Nanotoxicity of iron oxide nanoparticle internalization in growing neurons

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PET/MRI Dual-Modality Tumor Imaging Using Arginine-Glycine-Aspartic (RGD)–Conjugated Radiolabeled Iron Oxide Nanoparticles

Lee, H.-Y., Li, Z., Chen, K., Hsu, A. R., Xu, C., Xie, J., Sun, S., & Chen, X. (2008) · Journal of Nuclear Medicine · doi:10.2967/jnumed.108.051243 · Cited by 557

Characterization of Biophysical and Metabolic Properties of Cells Labeled with Superparamagnetic Iron Oxide Nanoparticles and Transfection Agent for Cellular MR Imaging

Arbab, A. S., Bashaw, L. A., Miller, B. R., Jordan, E. K., Lewis, B. K., Kalish, H., & Frank, J. A. (2003) · Radiology · doi:10.1148/radiol.2293021215 · Cited by 552

PEGylated Inorganic Nanoparticles

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Using Biofunctional Magnetic Nanoparticles to Capture Vancomycin-Resistant Enterococci and Other Gram-Positive Bacteria at Ultralow Concentration

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Thermotherapy of Prostate Cancer Using Magnetic Nanoparticles: Feasibility, Imaging, and Three-Dimensional Temperature Distribution

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Biodistribution of PEG-modified gold nanoparticles following intratracheal instillation and intravenous injection

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Dextran and albumin derivatised iron oxide nanoparticles: influence on fibroblasts in vitro

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Magnetic techniques for the isolation and purification of proteins and peptides

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Monocrystalline iron oxide nanocompounds (MION): Physicochemical properties

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One‐Pot Reaction to Synthesize Biocompatible Magnetite Nanoparticles

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Synthesis of Uniform Ferrimagnetic Magnetite Nanocubes

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Facile synthesis of superparamagnetic magnetite nanoparticles in liquid polyols

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Untitled work

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A nanoliter-scale nucleic acid processor with parallel architecture

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A Bifunctional Poly(ethylene glycol) Silane Immobilized on Metallic Oxide-Based Nanoparticles for Conjugation with Cell Targeting Agents

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Strongly emissive individual DNA-encapsulated Ag nanoclusters as single-molecule fluorophores

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The effect of thermotherapy using magnetic nanoparticles on rat malignant glioma

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Nitrilotriacetic Acid-Modified Magnetic Nanoparticles as a General Agent to Bind Histidine-Tagged Proteins

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Size and Surface Effects on the MRI Relaxivity of Manganese Ferrite Nanoparticle Contrast Agents

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Targeted delivery of antibiotics using liposomes and nanoparticles: research and applications

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A method for radiation-force localized drug delivery using gas-filled lipospheres

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PEG-Functionalized Magnetic Nanoparticles for Drug Delivery and Magnetic Resonance Imaging Applications

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Targeted Paclitaxel by Conjugation to Iron Oxide and Gold Nanoparticles

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Targeting stents with local delivery of paclitaxel-loaded magnetic nanoparticles using uniform fields

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Modified natural nanoparticles as contrast agents for medical imaging

Cormode, D. P., Jarzyna, P. A., Mulder, W. J. M., & Fayad, Z. A. (2010) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2009.11.005 · Cited by 197

Ultrasensitive Detection of Bacteria Using Core–Shell Nanoparticles and an NMR‐Filter System

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Antibody conjugated magnetic PLGA nanoparticles for diagnosis and treatment of breast cancer

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Temperature-Responsive Magnetite/PEO−PPO−PEO Block Copolymer Nanoparticles for Controlled Drug Targeting Delivery

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Diverse Applications of Nanomedicine

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Tuning the Magnetic Properties of Nanoparticles

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Imaging macrophages with nanoparticles

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Magnetic nanoparticles for environmental and biomedical applications: a review

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Chemical Synthesis and Assembly of Uniformly Sized Iron Oxide Nanoparticles for Medical Applications

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