The DOI matches its Crossref record; 167 of the 167 references it cites were found in a registry or an index.
Depression: A Decision-Theoretic Analysis
Open accessAbstract
The manifold symptoms of depression are common and often transient features of healthy life that are likely to be adaptive in difficult circumstances. It is when these symptoms enter a seemingly self-propelling spiral that the maladaptive features of a disorder emerge. We examine this malignant transformation from the perspective of the computational neuroscience of decision making, investigating how dysfunction of the brain's mechanisms of evaluation might lie at its heart. We start by considering the behavioral implications of pessimistic evaluations of decision variables. We then provide a selective review of work suggesting how such pessimism might arise via specific failures of the mechanisms of evaluation or state estimation. Finally, we analyze ways that miscalibration between the subject and environment may be self-perpetuating. We employ the formal framework of Bayesian decision theory as a foundation for this study, showing how most of the problems arise from one of its broad algorithmic facets, namely model-based reasoning.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“From a dynamical systems perspective, this corresponds to a pathological attractor state in neural activity (47, 48).”
From Predictive coding and neurocomputational psychiatry: a mechanistic framework for understanding mental disorders (2026) · cites this paper as [47]
Experimental — accuracy not yet measuredThe check wasn’t confident either way, so it gives no verdict — never disputed.
In the citing paper
“Bipolar disorder, marked by oscillations between manic (or hypo-manic) and depressive states, can be conceptualised in predictive coding terms as an instability in how the brain regulates precision across different states (47, 53).”
From Predictive coding and neurocomputational psychiatry: a mechanistic framework for understanding mental disorders (2026) · cites this paper as [47]
Experimental — accuracy not yet measuredIn the citing paper
“Efforts in computational psychiatry have sought to characterize changes in decision-making processes in the context of depression and have revealed dysfunction in the processes underlying model-based decision-making (for review see ref. 55).”
From Paying attention to attention in depression (2019) · cites this paper as [55]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Diagnostic and Statistical Manual of Mental Disorders
American Psychiatric Association (2013) · doi:10.1176/appi.books.9780890425596 · Cited by 116,369
Diagnostic and Statistical Manual of Mental Disorders
Williams, J. B. W., & First, M. B. (2013) · Oxford University Press eBooks · doi:10.1093/acrefore/9780199975839.013.104 · Cited by 109,845
REMEMBERING: A STUDY IN EXPERIMENTAL AND SOCIAL PSYCHOLOGY
Bartlett, F. C., & Burt, C. (1933) · British Journal of Educational Psychology · doi:10.1111/j.2044-8279.1933.tb02913.x · Cited by 7,475
Well-being : the foundations of hedonic psychology
Kahneman, D. J., Diener, E. F., & Schwarz, N. (1999) · Cited by 7,472
From inflammation to sickness and depression: when the immune system subjugates the brain
Dantzer, R., O'Connor, J. C., Freund, G. G., Johnson, R. W., & Kelley, K. W. (2008) · Nature Reviews Neuroscience · doi:10.1038/nrn2297 · Cited by 7,395
(1975) · Medical Entomology and Zoology · Cited by 7,245
Learned helplessness in humans: Critique and reformulation.
Abramson, L. Y., Seligman, M. E., & Teasdale, J. D. (1978) · Journal of Abnormal Psychology · doi:10.1037//0021-843x.87.1.49 · Cited by 7,121
Insel, T., Cuthbert, B., Garvey, M., Heinssen, R., Pine, D. S., Quinn, K., Sanislow, C., & Wang, P. (2010) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2010.09091379 · Cited by 7,067
Nolen-Hoeksema, S., Wisco, B. E., & Lyubomirsky, S. (2008) · Perspectives on Psychological Science · doi:10.1111/j.1745-6924.2008.00088.x · Cited by 5,172
Learning to predict by the methods of temporal differences
Sutton, R. S. (1988) · Machine Learning · doi:10.1007/bf00115009 · Cited by 5,148
Unrealistic optimism about future life events
Weinstein, N. D. (1980) · Journal of Personality and Social Psychology · doi:10.1037/0022-3514.39.5.806 · Cited by 4,999
Emotion regulation: affective, cognitive, and social consequences.
Gross, J. J. (2002) · Psychophysiology · doi:10.1017/s0048577201393198 · Cited by 4,890 · cited 1×
“Antecedent ER strategies (Gross 2002) are said to improve emotions by altering the situation or the interpretation of the emotional material one is exposed to before the emotion itself is experienced.”
BackgroundResponses to depression and their effects on the duration of depressive episodes
Nolen-Hoeksema, S. (1991) · Journal of Abnormal Psychology · doi:10.1037/0021-843x.100.4.569 · Cited by 4,529
What is the role of dopamine in reward: hedonic impact, reward learning, or incentive salience?
Berridge, K. C., & Robinson, T. E. (1998) · Brain Research Reviews · doi:10.1016/s0165-0173(98)00019-8 · Cited by 4,127
Rumination reconsidered: a psychometric analysis.
Treynor, W., Gonzalez, R., & Nolen-Hoeksema, S. (2003) · Cognitive Therapy and Research · doi:10.1023/a:1023910315561 · Cited by 3,808
Cognitive Therapy and the Emotional Disorders
Ince, L. P. (1977) · American Journal of Psychotherapy · doi:10.1176/appi.psychotherapy.1977.31.4.633 · Cited by 2,889
Advances in Neural Information Processing Systems 20
Bonilla, E. V., Chai, K. M. A., & Williams, C. K. I. (2008) · neural information processing systems · Cited by 2,701
Daw, N. D., Niv, Y., & Dayan, P. (2005) · Nature Neuroscience · doi:10.1038/nn1560 · Cited by 2,533
Self-citationEpidemiologic study of sleep disturbances and psychiatric disorders. An opportunity for prevention?
Ford, D. E. (1989) · JAMA · doi:10.1001/jama.262.11.1479 · Cited by 2,440
Cognition and Depression: Current Status and Future Directions
Gotlib, I. H., & Joormann, J. (2010) · Annual Review of Clinical Psychology · doi:10.1146/annurev.clinpsy.121208.131305 · Cited by 2,420
Bartlett, F. C., & Kintsch, W. (1995) · Cambridge University Press eBooks · doi:10.1017/cbo9780511759185 · Cited by 2,408
Epidemiologic Study of Sleep Disturbances and Psychiatric Disorders: An Opportunity for Prevention?
Ford, D. E. (1989) · JAMA · doi:10.1001/jama.1989.03430110069030 · Cited by 2,252
Cognitive impairment in depression: a systematic review and meta-analysis
Rock, P. L., Roiser, J. P., Riedel, W. J., & Blackwell, A. D. (2014) · Psychological Medicine · doi:10.1017/s0033291713002535 · Cited by 2,161
Cognitive vulnerability to emotional disorders
Mathews, A., & MacLeod, C. (2005) · Annual Review of Clinical Psychology · doi:10.1146/annurev.clinpsy.1.102803.143916 · Cited by 2,100
A framework for mesencephalic dopamine systems based on predictive Hebbian learning
Montague, P., Dayan, P., & Sejnowski, T. (1996) · The Journal of Neuroscience · doi:10.1523/jneurosci.16-05-01936.1996 · Cited by 2,066
Self-citationCognitive Psychology and Emotional Disorders
Williams, J. M. G. (1988) · UWA Profiles and Research Repository (UWA) · Cited by 1,871
Model-based influences on humans’ choices and striatal prediction errors
Daw, N. D., Gershman, S. J., Seymour, B., Dayan, P., & Dolan, R. J. (2011) · Neuron · doi:10.1016/j.neuron.2011.02.027 · Cited by 1,779
Self-citationAutobiographical memory specificity and emotional disorder.
Williams, J. M. G., Barnhofer, T., Crane, C., Herman, D., Raes, F., Watkins, E., & Dalgleish, T. (2007) · Psychological Bulletin · doi:10.1037/0033-2909.133.1.122 · Cited by 1,688
Reconsidering anhedonia in depression: Lessons from translational neuroscience
Treadway, M. T., & Zald, D. H. (2011) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2010.06.006 · Cited by 1,579
"Coherent Arbitrariness": Stable Demand Curves Without Stable Preferences
Dan Ariely, C., Loewenstein, G. F., & Prelec, D. (2003) · The Quarterly Journal of Economics · doi:10.1162/00335530360535153 · Cited by 1,462
Adaptive Coding of Reward Value by Dopamine Neurons
Tobler, P. N., Fiorillo, C. D., & Schultz, W. (2005) · Science · doi:10.1126/science.1105370 · Cited by 1,276
Pizzagalli, D. A., Holmes, A. J., Dillon, D. G., Goetz, E. L., Birk, J. L., Bogdan, R., Dougherty, D. D., Iosifescu, D. V., Rauch, S. L., & Fava, M. (2009) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2008.08081201 · Cited by 1,232
Hippocampal place-cell sequences depict future paths to remembered goals
Pfeiffer, B. E., & Foster, D. J. (2013) · Nature · doi:10.1038/nature12112 · Cited by 1,216
Response styles and the duration of episodes of depressed mood.
Nolen-Hoeksema, S., Morrow, J., & Fredrickson, B. L. (1993) · Journal of Abnormal Psychology · doi:10.1037/0021-843x.102.1.20 · Cited by 1,212
Depression and cortisol responses to psychological stress: A meta-analysis
Burke, H. M., Davis, M. C., Otte, C., & Mohr, D. C. (2005) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2005.02.010 · Cited by 1,194
Tonic dopamine: Opportunity costs and the control of response vigor
Niv, Y., Daw, N. D., Joel, D., & Dayan, P. (2007) · Psychopharmacology · doi:10.1007/s00213-006-0502-4 · Cited by 1,133
Self-citationThe Handbook of emotion elicitation and assessment
(2008) · Choice Reviews Online · doi:10.5860/choice.46-1769 · Cited by 1,128
Cognitive Psychology and Emotional Disorders
Wilhelm, S. A. (1998) · Journal of Behavior Therapy and Experimental Psychiatry · Cited by 1,101
Dopamine neurons modulate neural encoding and expression of depression-related behaviour
Tye, K. M., Mirzabekov, J. J., Warden, M. R., Ferenczi, E. A., Tsai, H.-C., Finkelstein, J., Kim, S.-Y., Adhikari, A., Thompson, K. R., Andalman, A. S., et al. (2013) · Nature · doi:10.1038/nature11740 · Cited by 1,073
Eye tracking of attention in the affective disorders: a meta-analytic review and synthesis
Armstrong, T., & Olatunji, B. O. (2012) · Clinical Psychology Review · doi:10.1016/j.cpr.2012.09.004 · Cited by 1,049 · cited 1×
“…refers to branches that start with a large loss eyes off it less rapidly (Caseras et al. 2007), spend more time examining it (Kellough et al. 2008, Armstrong & Olatunji 2012), show prolonged amygdala activation to it that persists into unrelated tasks (Siegle et al. 2002), and have a prolonged…”
BackgroundNeural ensembles in CA3 transiently encode paths forward of the animal at a decision point
Johnson, A., & Redish, A. D. (2007) · The Journal of Neuroscience · doi:10.1523/jneurosci.3761-07.2007 · Cited by 1,003
Contemporary Animal Learning Theory.
Abrahamson, D. (1981) · Europe PMC (PubMed Central) · Cited by 945
A meta-analysis of emotional reactivity in major depressive disorder
Bylsma, L. M., Morris, B. H., & Rottenberg, J. (2008) · Clinical Psychology Review · doi:10.1016/j.cpr.2007.10.001 · Cited by 933
Amat, J., Baratta, M. V., Paul, E., Bland, S. T., Watkins, L. R., & Maier, S. F. (2005) · Nature Neuroscience · doi:10.1038/nn1399 · Cited by 931
Contemporary Animal Learning Theory
LoLordo, V. M., & Dickinson, A. (1982) · The American Journal of Psychology · doi:10.2307/1422669 · Cited by 890
Orbitofrontal Cortex as a Cognitive Map of Task Space
Wilson, R. C., Takahashi, Y. K., Schoenbaum, G., & Niv, Y. (2014) · Neuron · doi:10.1016/j.neuron.2013.11.005 · Cited by 885
Siegle, G. J., Steinhauer, S. R., Thase, M. E., Stenger, V. A., & Carter, C. S. (2002) · Biological Psychiatry · doi:10.1016/s0006-3223(02)01314-8 · Cited by 859
Montague, P. R., Dolan, R. J., Friston, K. J., & Dayan, P. (2012) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2011.11.018 · Cited by 809
Self-citationDyna, an Integrated Architecture for Learning, Planning, and Reacting
Sutton, R. S. (1991) · ACM SIGART Bulletin · doi:10.1145/122344.122377 · Cited by 777
Coordination of Actions and Habits in the Medial Prefrontal Cortex of Rats
Killcross, S. (2003) · Cerebral Cortex · doi:10.1093/cercor/13.4.400 · Cited by 748
From reinforcement learning models to psychiatric and neurological disorders
Maia, T. V., & Frank, M. J. (2011) · Nature Neuroscience · doi:10.1038/nn.2723 · Cited by 746
Toward an objective characterization of an anhedonic phenotype: A signal-detection approach
Pizzagalli, D. A., Jahn, A. L., & O’Shea, J. P. (2005) · Biological Psychiatry · doi:10.1016/j.biopsych.2004.11.026 · Cited by 738
Maier, S. F., & Watkins, L. R. (2005) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2005.03.021 · Cited by 737
Self-perpetuating properties of dysphoric rumination.
Lyubomirsky, S., & Nolen-Hoeksema, S. (1993) · Journal of Personality and Social Psychology · doi:10.1037//0022-3514.65.2.339 · Cited by 709
Depression—Clinical, Experimental, and Theoretical Aspects
Strasburger, L. H. (1968) · Psychosomatic Medicine · doi:10.1097/00006842-196811000-00018 · Cited by 595
Joormann, J., & Gotlib, I. H. (2008) · Journal of Abnormal Psychology · doi:10.1037/0021-843x.117.1.182 · Cited by 594
Ehring, T., Tuschen-Caffier, B., Schnülle, J., Fischer, S., & Gross, J. J. (2010) · Emotion · doi:10.1037/a0019010 · Cited by 587 · cited 1×
“…ability to deploy adaptive strategies when they are explicitly instructed; rather, it is the frequency with which patients select these strategies spontaneously when left to themselves that is awry (Ehring et al. 2010, D’Avanzato et al. 2013, Dillon & Pizzagalli 2013, Joormann & Vanderlind 2014).”
BackgroundForbes, E. E., Hariri, A. R., Martin, S. L., Silk, J. S., Moyles, D. L., Fisher, P. M., Brown, S. M., Ryan, N. D., Birmaher, B., Axelson, D. A., et al. (2009) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2008.07081336 · Cited by 582
Decision theory, reinforcement learning, and the brain
Dayan, P., & Daw, N. D. (2008) · Cognitive, Affective, & Behavioral Neuroscience · doi:10.3758/cabn.8.4.429 · Cited by 580
Self-citationWhy Don't We Move Faster? Parkinson's Disease, Movement Vigor, and Implicit Motivation
Mazzoni, P., Hristova, A., & Krakauer, J. W. (2007) · The Journal of Neuroscience · doi:10.1523/jneurosci.0264-07.2007 · Cited by 557
Harmer, C. J., Goodwin, G. M., & Cowen, P. J. (2009) · British Journal of Psychiatry · doi:10.1192/bjp.bp.108.051193 · Cited by 542
Targeted electrode-based modulation of neural circuits for depression.
Mayberg, H. S. (2009) · Journal of Clinical Investigation · doi:10.1172/jci38454 · Cited by 542
Cognitive Mechanisms of Treatment in Depression
Roiser, J. P., Elliott, R., & Sahakian, B. J. (2012) · Neuropsychopharmacology · doi:10.1038/npp.2011.183 · Cited by 535
Fales, C. L., Barch, D. M., Rundle, M. M., Mintun, M. A., Snyder, A. Z., Cohen, J. D., Mathews, J., & Sheline, Y. I. (2008) · Biological Psychiatry · doi:10.1016/j.biopsych.2007.06.012 · Cited by 517
A unified framework for addiction: Vulnerabilities in the decision process
Redish, A. D., Jensen, S., & Johnson, A. (2008) · Behavioral and Brain Sciences · doi:10.1017/s0140525x0800472x · Cited by 501
Subliminal processing of emotional information in anxiety and depression.
Mogg, K., Bradley, B. P., Williams, R. M., & Mathews, A. (1993) · Journal of Abnormal Psychology · doi:10.1037//0021-843x.102.2.304 · Cited by 498
Subliminal processing of emotional information in anxiety and depression.
Mogg, K., Bradley, B. P., Williams, R., & Mathews, A. (1993) · Journal of Abnormal Psychology · doi:10.1037/0021-843x.102.2.304 · Cited by 497
Neural Responses to Monetary Incentives in Major Depression
Knutson, B., Bhanji, J. P., Cooney, R. E., Atlas, L. Y., & Gotlib, I. H. (2008) · Biological Psychiatry · doi:10.1016/j.biopsych.2007.07.023 · Cited by 496
Cohen, J. D., Braver, T. S., & O´Reilly, R. (1996) · Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences · doi:10.1098/rstb.1996.0138 · Cited by 487
Expected value and prediction error abnormalities in depression and schizophrenia
Gradin, V. B., Kumar, P., Waiter, G., Ahearn, T., Stickle, C., Milders, M., Reid, I., Hall, J., & Steele, J. D. (2011) · Brain · doi:10.1093/brain/awr059 · Cited by 485
Mapping anhedonia onto reinforcement learning: a behavioural meta-analysis
Huys, Q. J., Pizzagalli, D. A., Bogdan, R., & Dayan, P. (2013) · Biology of Mood & Anxiety Disorders · doi:10.1186/2045-5380-3-12 · Cited by 480
Self-citationSelf-perpetuating properties of dysphoric rumination.
Lyubomirsky, S., & Nolen–Hoeksema, S. (1993) · Journal of Personality and Social Psychology · doi:10.1037/0022-3514.65.2.339 · Cited by 480
Borkovec, T. D., & Roemer, L. (1995) · Journal of Behavior Therapy and Experimental Psychiatry · doi:10.1016/0005-7916(94)00064-s · Cited by 469
Serotonin and dopamine: unifying affective, activational, and decision functions.
Cools, R., Nakamura, K., & Daw, N. D. (2011) · Neuropsychopharmacology · doi:10.1038/npp.2010.121 · Cited by 464
Self-citationOpponency revisited: competition and cooperation between dopamine and serotonin
Boureau, Y.-L., & Dayan, P. (2011) · Neuropsychopharmacology · doi:10.1038/npp.2010.151 · Cited by 456
Self-citationHuys, Q. J. M., Eshel, N., O'Nions, E., Sheridan, L., Dayan, P., & Roiser, J. P. (2012) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1002410 · Cited by 439
Self-citationA meta-analysis of neurofunctional imaging studies of emotion and cognition in major depression
Diener, C., Kuehner, C., Brusniak, W., Ubl, B., Wessa, M., & Flor, H. (2012) · NeuroImage · doi:10.1016/j.neuroimage.2012.04.005 · Cited by 428
Fu, C. H. Y., Steiner, H., & Costafreda, S. G. (2013) · Neurobiology of Disease · doi:10.1016/j.nbd.2012.05.008 · Cited by 399
The misbehavior of value and the discipline of the will
Dayan, P., Niv, Y., Seymour, B., & Daw, N. D. (2006) · Neural Networks · doi:10.1016/j.neunet.2006.03.002 · Cited by 398
Self-citationEmotion Regulation in Depression
Joormann, J., & Vanderlind, W. M. (2014) · Clinical Psychological Science · doi:10.1177/2167702614536163 · Cited by 390
Abnormal temporal difference reward-learning signals in major depression
Kumar, P., Waiter, G., Ahearn, T., Milders, M., Reid, I., & Steele, J. D. (2008) · Brain · doi:10.1093/brain/awn136 · Cited by 374
Zhang, W.-N., Chang, S.-H., Guo, L.-Y., Zhang, K.-L., & Wang, J. (2013) · Journal of Affective Disorders · doi:10.1016/j.jad.2013.06.039 · Cited by 355
Handbook of Emotion Elicitation and Assessment
(2007) · doi:10.1093/oso/9780195169157.001.0001 · Cited by 348
Speed/accuracy trade-off between the habitual and the goal-directed processes
Keramati, M., Dezfouli, A., & Piray, P. (2011) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1002055 · Cited by 346
Tremblay, L. K., Naranjo, C. A., Graham, S. J., Herrmann, N., Mayberg, H. S., Hevenor, S., & Busto, U. E. (2005) · Archives of General Psychiatry · doi:10.1001/archpsyc.62.11.1228 · Cited by 340
Affective Cognition and its Disruption in Mood Disorders
Elliott, R., Zahn, R., Deakin, J. F. W., & Anderson, I. M. (2011) · Neuropsychopharmacology · doi:10.1038/npp.2010.77 · Cited by 330
fMRI of alterations in reward selection, anticipation, and feedback in major depressive disorder
Smoski, M. J., Felder, J., Bizzell, J., Green, S. R., Ernst, M., Lynch, T. R., & Dichter, G. S. (2009) · Journal of Affective Disorders · doi:10.1016/j.jad.2009.01.034 · Cited by 328
Alloy, L. B., Abramson, L. Y., Whitehouse, W. G., Hogan, M. E., Tashman, N. A., Steinberg, D. L., Rose, D. T., & Donovan, P. (1999) · Behaviour Research and Therapy · doi:10.1016/s0005-7967(98)00157-0 · Cited by 327
The Psychobiology of the Depressive Disorders: Implications for the Effects of Stress
Dünner, D. L. (1980) · American Journal of Psychiatry · doi:10.1176/ajp.137.8.1005-a · Cited by 317
Individual differences in trait rumination and the neural systems supporting cognitive reappraisal
RAY, R. D., OCHSNER, K. N., COOPER, J. C., ROBERTSON, E. R., GABRIELI, J. D. E., & GROSS, J. J. (2005) · Cognitive, Affective, & Behavioral Neuroscience · doi:10.3758/cabn.5.2.156 · Cited by 316
Time course of selective attention in clinically depressed young adults: An eye tracking study
Kellough, J. L., Beevers, C. G., Ellis, A. J., & Wells, T. T. (2008) · Behaviour Research and Therapy · doi:10.1016/j.brat.2008.07.004 · Cited by 314
Reward‐related decision‐making in pediatric major depressive disorder: an fMRI study
Forbes, E. E., Christopher May, J., Siegle, G. J., Ladouceur, C. D., Ryan, N. D., Carter, C. S., Birmaher, B., Axelson, D. A., & Dahl, R. E. (2006) · Journal of Child Psychology and Psychiatry · doi:10.1111/j.1469-7610.2006.01673.x · Cited by 299 · cited 1×
“This is expected to be present even in the absence of learning (Forbes et al. 2006, 2009; Knutson et al. 2008; Pizzagalli et al. 2009; Smoski et al. 2009; Robinson et al. 2012).”
BackgroundAttentional bias in dysphoria: The role of inhibitory processes
Joormann, J. (2004) · Cognition & Emotion · doi:10.1080/02699930244000480 · Cited by 298
MURPHY, F. C., MICHAEL, A., ROBBINS, T. W., & SAHAKIAN, B. J. (2003) · Psychological Medicine · doi:10.1017/s0033291702007018 · Cited by 298
The relationship between rumination, avoidance and depression in a non-clinical sample.
Moulds, M. L., Kandris, E., Starr, S., & Wong, A. C. M. (2007) · Behaviour Research and Therapy · doi:10.1016/j.brat.2006.03.003 · Cited by 289
Elliott, R., Sahakian, B. J., Herrod, J. J., Robbins, T. W., & Paykel, E. S. (1997) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp.63.1.74 · Cited by 285
Decreased motivation during chronic pain requires long-term depression in the nucleus accumbens
Schwartz, N., Temkin, P., Jurado, S., Lim, B. K., Heifets, B. D., Polepalli, J. S., & Malenka, R. C. (2014) · Science · doi:10.1126/science.1253994 · Cited by 278
Are emotions frightening? An extension of the fear of fear construct
Williams, K. E., Chambless, D. L., & Ahrens, A. (1997) · Behaviour Research and Therapy · doi:10.1016/s0005-7967(96)00098-8 · Cited by 275
Crockett, M. J., Clark, L., & Robbins, T. W. (2009) · The Journal of Neuroscience · doi:10.1523/jneurosci.2513-09.2009 · Cited by 271
Lamers, F., de Jonge, P., Nolen, W. A., Smit, J. H., Zitman, F. G., Beekman, A. T. F., & Penninx, B. W. J. H. (2010) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.09m05398blu · Cited by 264
Serotonin, inhibition, and negative mood
Dayan, P., & Huys, Q. J. M. (2008) · PLoS Computational Biology · doi:10.1371/journal.pcbi.0040004 · Cited by 263
Self-citationLocalized microstimulation of primate pregenual cingulate cortex induces negative decision-making
Amemori, K.-I., & Graybiel, A. M. (2012) · Nature Neuroscience · doi:10.1038/nn.3088 · Cited by 262
Blunted response to feedback information in depressive illness
Steele, J. D., Kumar, P., & Ebmeier, K. P. (2007) · Brain · doi:10.1093/brain/awm150 · Cited by 261
Causal attributions and perinatal depression.
Cutrona, C. E. (1983) · Journal of Abnormal Psychology · doi:10.1037/0021-843x.92.2.161 · Cited by 258
Striatal dysfunction during reversal learning in unmedicated schizophrenia patients
Schlagenhauf, F., Huys, Q. J. M., Deserno, L., Rapp, M. A., Beck, A., Heinze, H.-J., Dolan, R., & Heinz, A. (2014) · NeuroImage · doi:10.1016/j.neuroimage.2013.11.034 · Cited by 253
Self-citationJoormann, J. (2006) · Cognitive Therapy and Research · doi:10.1007/s10608-006-9035-8 · Cited by 247
An investigation of the relationship between positive affect regulation and depression
Werner-Seidler, A., Banks, R., Dunn, B. D., & Moulds, M. L. (2013) · Behaviour Research and Therapy · doi:10.1016/j.brat.2012.11.001 · Cited by 241
D’Avanzato, C., Joormann, J., Siemer, M., & Gotlib, I. H. (2013) · Cognitive Therapy and Research · doi:10.1007/s10608-013-9537-0 · Cited by 239
Behavioral control, the medial prefrontal cortex, and resilience
Maier, S. F., Amat, J., Baratta, M. V., Paul, E. D., & Watkins, L. R. (2006) · Dialogues in Clinical Neuroscience · doi:10.31887/dcns.2006.8.4/smaier · Cited by 238
Robinson, O. J., Cools, R., Carlisi, C. O., Sahakian, B. J., & Drevets, W. C. (2012) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2011.11010137 · Cited by 232
Taste and smell perception in depression.
Amsterdam, J., Settle, R., Doty, R. L., Abelman, E., & Winokur, A. (1987) · Biological Psychiatry · doi:10.1016/0006-3223(87)90108-9 · Cited by 231
Neural basis of abnormal response to negative feedback in unmedicated mood disorders
Taylor Tavares, J. V., Clark, L., Furey, M. L., Williams, G. B., Sahakian, B. J., & Drevets, W. C. (2008) · NeuroImage · doi:10.1016/j.neuroimage.2008.05.049 · Cited by 229
Tremblay, L. K., Naranjo, C. A., Cardenas, L., Herrmann, N., & Busto, U. E. (2002) · Archives of General Psychiatry · doi:10.1001/archpsyc.59.5.409 · Cited by 229
Contributions of the ventromedial prefrontal cortex to goal-directed action selection
O’Doherty, J. P. (2011) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2011.06290.x · Cited by 225
Retrospective revaluation in sequential decision making: a tale of two systems
Gershman, S. J., Markman, A. B., & Otto, A. R. (2014) · Journal of Experimental Psychology General · doi:10.1037/a0030844 · Cited by 217
Measuring hedonic capacity in depression: A psychometric analysis of three anhedonia scales
Leventhal, A. M., Chasson, G. S., Tapia, E., Miller, E. K., & Pettit, J. W. (2006) · Journal of Clinical Psychology · doi:10.1002/jclp.20327 · Cited by 211
Joormann, J., Levens, S. M., & Gotlib, I. H. (2011) · Psychological Science · doi:10.1177/0956797611415539 · Cited by 209
Williams, A. D., Blackwell, S. E., Mackenzie, A., Holmes, E. A., & Andrews, G. (2013) · Journal of Consulting and Clinical Psychology · doi:10.1037/a0033247 · Cited by 206
Interaction between emotional state and learning underlies mood instability
Eldar, E., & Niv, Y. (2015) · Nature Communications · doi:10.1038/ncomms7149 · Cited by 205
Erickson, K., Drevets, W. C., Clark, L., Cannon, D. M., Bain, E. E., Zarate, C. A., Charney, D. S., & Sahakian, B. J. (2005) · American Journal of Psychiatry · doi:10.1176/appi.ajp.162.11.2171 · Cited by 203
What and where: A Bayesian inference theory of attention
Chikkerur, S. S., Serre, T., Tan, C., & Poggio, T. (2010) · Vision Research · doi:10.1016/j.visres.2010.05.013 · Cited by 202
Depression: A Psychobiological Synthesis
Willner, P. (1985) · Medical Entomology and Zoology · Cited by 199
Blackwell, S. E., & Holmes, E. A. (2010) · Applied Cognitive Psychology · doi:10.1002/acp.1680 · Cited by 196
The algorithmic anatomy of model-based evaluation
Daw, N. D., & Dayan, P. (2014) · Philosophical Transactions of the Royal Society B: Biological Sciences · doi:10.1098/rstb.2013.0478 · Cited by 195
Self-citationChase, H., Frank, M., Michael, A., Bullmore, E., Sahakian, B., & Robbins, T. (2009) · Psychological Medicine · doi:10.1017/s0033291709990468 · Cited by 194
Biases in visual orienting to negative and positive scenes in dysphoria: an eye movement study.
Caseras, X., Garner, M., Bradley, B. P., & Mogg, K. (2007) · Journal of Abnormal Psychology · doi:10.1037/0021-843x.116.3.491 · Cited by 189
Lautenbacher, S., Hemmeter-Spernal, J., Schreiber, W., & Krieg, J.-C. (1999) · Psychosomatic Medicine · doi:10.1097/00006842-199911000-00015 · Cited by 186
Berlin, I., Givry-Steiner, L., Lecrubier, Y., & Puech, A. (1998) · European Psychiatry · doi:10.1016/s0924-9338(98)80048-5 · Cited by 178
Unipolar depression does not moderate responses to the Sweet Taste Test
Dichter, G. S., Smoski, M. J., Kampov-Polevoy, A. B., Gallop, R., & Garbutt, J. C. (2010) · Depression and Anxiety · doi:10.1002/da.20690 · Cited by 175
Clinical and psychometric correlates of dopamine D2 binding in depression
SHAH, P. J., OGILVIE, A. D., GOODWIN, G. M., & EBMEIER, K. P. (1997) · Psychological Medicine · doi:10.1017/s0033291797005382 · Cited by 170
Neuroreceptor imaging in depression
Savitz, J. B., & Drevets, W. C. (2012) · Neurobiology of Disease · doi:10.1016/j.nbd.2012.06.001 · Cited by 165
Sloan (1997) · doi:10.1016/s0165-0327(97)00097-9 · Cited by 163
Interpretation revealed in the blink of an eye: Depressive bias in the resolution of ambiguity.
Lawson, C., MacLeod, C., & Hammond, G. (2002) · Journal of Abnormal Psychology · doi:10.1037//0021-843x.111.2.321 · Cited by 157
Interpretation revealed in the blink of an eye: depressive bias in the resolution of ambiguity
Lawson, C., MacLeod, C., & Hammond, G. (2002) · Journal of Abnormal Psychology · doi:10.1037/0021-843x.111.2.321 · Cited by 157
Psychostimulants for depression
Candy, B., Jones, L., Williams, R., Tookman, A., & King, M. (2008) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd006722.pub2 · Cited by 156
A Bayesian formulation of behavioral control
Huys, Q. J. M., & Dayan, P. (2009) · Cognition · doi:10.1016/j.cognition.2009.01.008 · Cited by 150
Self-citationNegative Interpretation Bias in Individuals with Depressive Symptoms
Hindash, A. C., & Amir, N. (2011) · Cognitive Therapy and Research · doi:10.1007/s10608-011-9397-4 · Cited by 132
Dynamics of attentional selection under conflict: Toward a rational Bayesian account.
Yu, A. J., Dayan, P., & Cohen, J. D. (2009) · Journal of Experimental Psychology Human Perception & Performance · doi:10.1037/a0013553 · Cited by 131
Self-citationHaeffel, G. J., Abramson, L. Y., Brazy, P. C., Shah, J. Y., Teachman, B. A., & Nosek, B. A. (2006) · Behaviour Research and Therapy · doi:10.1016/j.brat.2006.09.003 · Cited by 130
Remijnse, P. L., Nielen, M. M. A., van Balkom, A. J. L. M., Hendriks, G.-J., Hoogendijk, W. J., Uylings, H. B. M., & Veltman, D. J. (2009) · Psychological Medicine · doi:10.1017/s0033291708005072 · Cited by 127
Negative Cognitive Biases Predict Subsequent Depression
Rude, S. S., Valdez, C. R., Odom, S., & Ebrahimi, A. (2003) · Cognitive Therapy and Research · doi:10.1023/a:1025472413805 · Cited by 126
Clepce, M., Gossler, A., Reich, K., Kornhuber, J., & Thuerauf, N. (2010) · Neuroscience Letters · doi:10.1016/j.neulet.2010.01.027 · Cited by 116
Dombrovski, A. Y., Cyranowski, J. M., Mulsant, B. H., Houck, P. R., Buysse, D. J., Andreescu, C., Thase, M. E., Mallinger, A. G., & Frank, E. (2008) · Depression and Anxiety · doi:10.1002/da.20467 · Cited by 116
Rumination in Clinical Depression: A Type of Emotional Suppression?
Liverant, G. I., Kamholz, B. W., Sloan, D. M., & Brown, T. A. (2010) · Cognitive Therapy and Research · doi:10.1007/s10608-010-9304-4 · Cited by 112
Holmes, A. J., & Pizzagalli, D. A. (2007) · Emotion · doi:10.1037/1528-3542.7.1.68 · Cited by 110
How to set the switches on this thing
Dayan, P. (2012) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2012.05.011 · Cited by 107
Self-citationPain perception in depression: relationships to symptomatology and naloxone-sensitive mechanisms.
Lautenbacher, S., Roscher, S., Strian, D., Fassbender, K., Krumrey, K., & Krieg, J. C. (1994) · Psychosomatic Medicine · doi:10.1097/00006842-199407000-00010 · Cited by 104
The role of learning-related dopamine signals in addiction vulnerability
Huys, Q. J. M., Tobler, P. N., Hasler, G., & Flagel, S. B. (2014) · Progress in brain research · doi:10.1016/b978-0-444-63425-2.00003-9 · Cited by 92
Self-citationDillon, D. G., & Pizzagalli, D. A. (2013) · Psychiatry Research: Neuroimaging · doi:10.1016/j.pscychresns.2013.01.001 · Cited by 91
Unconscious memory bias in depression: Perceptual and conceptual processes.
Watkins, P. C., Martin, C. K., & Stern, L. D. (2000) · Journal of Abnormal Psychology · doi:10.1037/0021-843x.109.2.282 · Cited by 85
Huys, Q. J. M., Guitart‐Masip, M., Dolan, R. J., & Dayan, P. (2015) · Clinical Psychological Science · doi:10.1177/2167702614562040 · Cited by 85
Self-citationDiagnosing Major Depressive Disorder VIII: Are Some Symptoms Better Than Others?
McGlinchey, J. B., Zimmerman, M., Young, D., & Chelminski, I. (2006) · Journal of Nervous & Mental Disease · doi:10.1097/01.nmd.0000240222.75201.aa · Cited by 77
Performance feedback deficit in geriatric depression
Steffens, D. C., Wagner, H. R., Levy, R. M., Horn, K. A., & Krishnan, K. (2001) · Biological Psychiatry · doi:10.1016/s0006-3223(01)01165-9 · Cited by 70
Depression. A Psychobiological Synthesis
Lipper, S. (1986) · American Journal of Psychotherapy · doi:10.1176/appi.psychotherapy.1986.40.3.469 · Cited by 70
López‐Solà, M., Pujol, J., Hernández‐Ribas, R., Harrison, B. J., Contreras‐Rodríguez, O., Soriano‐Mas, C., Deus, J., Ortiz, H., Menchón, J. M., Vallejo, J., et al. (2010) · Neuropsychopharmacology · doi:10.1038/npp.2010.108 · Cited by 69
Mitchell, A. J., McGlinchey, J. B., Young, D., Chelminski, I., & Zimmerman, M. A. (2008) · Psychological Medicine · doi:10.1017/s0033291708004674 · Cited by 67
Depression and Implicit Memory: Understanding Mood Congruent Memory Bias
Barry, E. S., Naus, M. J., & Rehm, L. P. (2004) · Cognitive Therapy and Research · doi:10.1023/b:cotr.0000031808.00502.2e · Cited by 66
Iacoviello, B. M., Alloy, L. B., Abramson, L. Y., & Choi, J. Y. (2010) · Journal of Abnormal Psychology · doi:10.1037/a0020114 · Cited by 64
Computational psychiatry (vol 16, pg 72, 2012)
Montague, P. R., Dolan, R. J., Friston, K. J., & Dayan, P. (2012) · UCL Discovery (University College London) · Cited by 64
Self-citationOptimism as a Prior Belief about the Probability of Future Reward
Stankevicius, A., Huys, Q. J. M., Kalra, A., & Seriès, P. (2014) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1003605 · Cited by 62
Self-citationA rational analysis of the effects of memory biases on serial reproduction
Xu, J., & Griffiths, T. L. (2009) · Cognitive Psychology · doi:10.1016/j.cogpsych.2009.09.002 · Cited by 56
Implicit interpretation biases affect emotional vulnerability: A training study
Tran, T. B., Siemer, M., & Joormann, J. (2011) · Cognition & Emotion · doi:10.1080/02699931.2010.532393 · Cited by 42
Learned helplessness and generalization
Lieder, F., Goodman, N. D., & Huys, Q. J. M. (2013) · eScholarship (California Digital Library) · doi:10.5167/uzh-91430 · Cited by 24
Self-citationReinforcers and control : towards a computational aetiology of depression
Huys, Q. J. M. (2007) · UCL Discovery (University College London) · Cited by 16
Self-citationMetareasoning for Monte Carlo Tree Search
Hay, N., & Russell, S. (2011) · UC Berkeley · Cited by 12
Haeffel, G. J. (2010) · Cognitive Therapy and Research · doi:10.1007/s10608-010-9298-y · Cited by 11
A metacognitive model and therapy for generalized anxiety disorder
Wells, A. (1999) · Clinical Psychology & Psychotherapy · doi:10.1002/(sici)1099-0879(199905)6:2
Research works printed but not linked: 5
- 10.1037/0021-843X.87.1.49 · DOI · Paper page
- Candy M, 2008, Cochrane Database Syst. Rev., 2008, CD006722
- Lewinsohn P, 1979, The Psychobiology of Depressive Disorders: Implications for the Effects of Stress, 291
- Marr D, 1982, Vision
- World Health Organ, 1990, The ICD-10 Classification of Mental and Behavioural Disorders: Clinical Descriptions and Diagnostic Guidelines
Cited by
Sorted by citations
Computational psychiatry as a bridge from neuroscience to clinical applications
Huys, Q. J. M., Maia, T. V., & Frank, M. J. (2016) · Nature Neuroscience · doi:10.1038/nn.4238 · Cited by 1,002
Self-citationNeuroscience of apathy and anhedonia: a transdiagnostic approach
Husain, M., & Roiser, J. P. (2018) · Nature reviews. Neuroscience · doi:10.1038/s41583-018-0029-9 · Cited by 682
A distributional code for value in dopamine-based reinforcement learning
Dabney, W., Kurth-Nelson, Z. L., Uchida, N., Starkweather, C. K., Hassabis, D., Munos, R., & Botvinick, M. (2020) · Nature · doi:10.1038/s41586-019-1924-6 · Cited by 462
LeDoux, J. E., & Daw, N. D. (2018) · Nature reviews. Neuroscience · doi:10.1038/nrn.2018.22 · Cited by 405
Self-citationMood as representation of momentum
Eldar, E., Rutledge, R. B., Dolan, R. J., & Niv, Y. (2016) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2015.07.010 · Cited by 383
Metadata
- Authors
- Huys, Q. J. M., Daw, N. D., & Dayan, P.
- Affiliations
- University of Zurich (CH)
- New York University (US)
- Gatsby Computational Neuroscience Unit (GB)
- Venue
- Annual Review of Neuroscience
- Publisher
- Annual Reviews
- Published
- 2015-07-08
- Volume
- 38
- Issue
- 1
- Pages
- 1-23
- ISSN
- 0147-006X (ISSN-L)
- 1545-4126
- OpenAlex
- W2164531443
- Cited by
- 221
- References
- 165
- Citations by year
- 2026: 18 · 2025: 16 · 2024: 24 · 2023: 35 · 2022: 28 · 2021: 20 · 2020: 22 · 2019: 15 · 2018: 14 · 2017: 14 · 2016: 8 · 2015: 7
- FWCI
- 1.43
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Annual Review of Neuroscience (publishedVersion)
- PubMed (publishedVersion)
- UCL Discovery (University College London) (submittedVersion)
- MPG.PuRe (Max Planck Society) (submittedVersion)
- Zurich Open Repository and Archive (University of Zurich) (submittedVersion)
- Funders
- Wellcome Trust (091593)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Social Sciences › Decision Sciences › General Decision Sciences › Decision-Making and Behavioral Economics
- Keywords
- depression, decision-making, Bayesian decision theory, model-based reasoning, pessimism, state estimation, computational psychiatry, adaptive behavior
- MeSH terms
- Bayes Theorem, Decision Making, Decision Theory, Depression, Humans
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review