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Cited by 406

The DOI matches its Crossref record; 279 of the 279 references it cites were found in a registry or an index.

Cell Migration

Open access
Trepat, Xavier, Chen, Zaozao, Jacobson, Ken·2012·Comprehensive Physiology
DOI 10.1002/cphy.c110012
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Abstract

Cell migration is fundamental to establishing and maintaining the proper organization of multicellular organisms. Morphogenesis can be viewed as a consequence, in part, of cell locomotion, from large‐scale migrations of epithelial sheets during gastrulation, to the movement of individual cells during development of the nervous system. In an adult organism, cell migration is essential for proper immune response, wound repair, and tissue homeostasis, while aberrant cell migration is found in various pathologies. Indeed, as our knowledge of migration increases, we can look forward to, for example, abating the spread of highly malignant cancer cells, retarding the invasion of white cells in the inflammatory process, or enhancing the healing of wounds. This article is organized in two main sections. The first section is devoted to the single‐cell migrating in isolation such as occurs when leukocytes migrate during the immune response or when fibroblasts squeeze through connective tissue. The second section is devoted to cells collectively migrating as part of multicellular clusters or sheets. This second type of migration is prevalent in development, wound healing, and in some forms of cancer metastasis.© 2012 American Physiological Society.Compr Physiol 2:2369‐2392, 2012.

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Metadata

Authors
Trepat, X., Chen, Z., & Jacobson, K.
Venue
Comprehensive Physiology
Publisher
Wiley
Published
2012-10
Volume
2
Issue
4
Pages
2369-2392
ISSN
2040-4603 (ISSN-L)
DOI
10.1002/cphy.c110012
OpenAlex
W4211202579
Cited by
406
References
279
Type
other
Language
en
Open access
green

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