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Ketogenic diets, physical activity and body composition: a review

Ashtary-Larky, Damoon, Bagheri, Reza, Bavi, Hoda, Baker, Julien S., Moro, Tatiana, Mancin, Laura, Paoli, Antonio·2022·British Journal of Nutrition
DOI 10.1017/s0007114521002609PMC PMC9244428
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Abstract

Obesity remains a serious relevant public health concern throughout the world despite related countermeasures being well understood (i.e. mainly physical activity and an adjusted diet). Among different nutritional approaches, there is a growing interest in ketogenic diets (KD) to manipulate body mass (BM) and to enhance fat mass loss. KD reduce the daily amount of carbohydrate intake drastically. This results in increased fatty acid utilisation, leading to an increase in blood ketone bodies (acetoacetate, 3- β -hydroxybutyrate and acetone) and therefore metabolic ketosis. For many years, nutritional intervention studies have focused on reducing dietary fat with little or conflicting positive results over the long term. Moreover, current nutritional guidelines for athletes propose carbohydrate-based diets to augment muscular adaptations. This review discusses the physiological basis of KD and their effects on BM reduction and body composition improvements in sedentary individuals combined with different types of exercise (resistance training or endurance training) in individuals with obesity and athletes. Ultimately, we discuss the strengths and the weaknesses of these nutritional interventions together with precautionary measures that should be observed in both individuals with obesity and athletic populations. A literature search from 1921 to April 2021 using Medline, Google Scholar, PubMed, Web of Science, Scopus and Sportdiscus Databases was used to identify relevant studies. In summary, based on the current evidence, KD are an efficient method to reduce BM and body fat in both individuals with obesity and athletes. However, these positive impacts are mainly because of the appetite suppressive effects of KD, which can decrease daily energy intake. Therefore, KD do not have any superior benefits to non-KD in BM and body fat loss in individuals with obesity and athletic populations in an isoenergetic situation. In sedentary individuals with obesity, it seems that fat-free mass (FFM) changes appear to be as great, if not greater, than decreases following a low-fat diet. In terms of lean mass, it seems that following a KD can cause FFM loss in resistance-trained individuals. In contrast, the FFM-preserving effects of KD are more efficient in endurance-trained compared with resistance-trained individuals.

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Research works printed but not linked: 270

  1. 10.1111/j.1528-1167.2005.00282.x · DOI · Paper page
  2. 10.1093/ajcn/86.2.276 · DOI · Paper page
  3. Freeman, 2006, The ketogenic diet: from molecular mechanisms to clinical effects, Epilepsy Res, 68, 145, 10.1016/j.eplepsyres.2005.10.003 · DOI · Paper page
  4. 10.1007/s00421-005-0127-z · DOI · Paper page
  5. Burke, 2006, Energy and carbohydrate for training and recovery, J Sports Sci, 24, 675, 10.1080/02640410500482602 · DOI · Paper page
  6. 10.1001/jama.293.1.43 · DOI · Paper page
  7. Yamaguchi, 2011, Effect of exercise performed at anaerobic threshold on serum growth hormone and body fat distribution in obese patients with type 2 diabetes, Obes Res Clin Pract, 5, e9, 10.1016/j.orcp.2010.11.001 · DOI
  8. Paoli, 2021, Effects of two months of very low carbohydrate ketogenic diet on body composition, muscle strength, muscle area, and blood parameters in competitive natural body builders, Nutrients, 13, 374, 10.3390/nu13020374 · DOI
  9. Turcotte, 1999, Role of fats in exercise: types and quality, Clin Sports Med, 18, 485, 10.1016/S0278-5919(05)70163-0 · DOI
  10. 10.1586/14737175.2015.1044982 · DOI
  11. Wylie-Rosett, 2013, Health effects of low-carbohydrate diets: where should new research go?, Curr Diabetes Rep, 13, 271, 10.1007/s11892-012-0357-5 · DOI
  12. 10.1080/10408690091189248 · DOI
  13. 10.2337/diabetes.52.6.1377 · DOI
  14. 10.1186/1743-7075-1-15 · DOI · Paper page
  15. Despres, 1984, The effect of a 20-week endurance training program on adipose-tissue morphology and lipolysis in men and women, Metabolism, 33, 235, 10.1016/0026-0495(84)90043-X · DOI
  16. Churuangsuk, 2019, Impacts of carbohydrate-restricted diets on micronutrient intakes and status: a systematic review, Obes Rev, 20, 1132, 10.1111/obr.12857 · DOI · Paper page
  17. Møller, 2007, Growth hormone effects on protein metabolism, Endocrinol Metab Clin, 36, 89, 10.1016/j.ecl.2006.11.001 · DOI
  18. Stubbs, 1996, Breakfasts high in protein, fat or carbohydrate: effect on within-day appetite and energy balance, Eur J Clin Nutr, 50, 409
  19. Cohen, 2019, A ketogenic diet is acceptable in women with ovarian and endometrial cancer and has no adverse effects on blood lipids: a randomized, controlled trial, Nutr Cancer, 1
  20. Balasse, 1989, Ketone body production and disposal: effects of fasting, diabetes, and exercise, Diabetes/Metab Rev, 5, 247, 10.1002/dmr.5610050304 · DOI · Paper page
  21. Durkalec-Michalski, 2019, Effect of a four-week ketogenic diet on exercise metabolism in CrossFit-trained athletes, J Int Soc Sports Nutr, 16, 16, 10.1186/s12970-019-0284-9 · DOI
  22. 10.1186/1475-2891-10-112 · DOI
  23. Robinson, 1980, Physiological roles of ketone bodies as substrates and signals in mammalian tissues, Physiol Rev, 60, 143, 10.1152/physrev.1980.60.1.143 · DOI · Paper page
  24. 10.1038/sj.ijo.0803075 · DOI
  25. Koulmann, 2000, Use of bioelectrical impedance analysis to estimate body fluid compartments after acute variations of the body hydration level, Med Sci Sports Exerc, 32, 857, 10.1097/00005768-200004000-00020 · DOI
  26. 10.7326/0003-4819-142-6-200503150-00006 · DOI · Paper page
  27. Tinsley, 2016, Fat-Free mass changes during ketogenic diets and the potential role of resistance training, Int J Sport Nutr Exercise Metab, 26, 78, 10.1123/ijsnem.2015-0070 · DOI · Paper page
  28. Nelson, 2008, Lehninger Principles of Biochemistry
  29. 211. Haghighat, N , Ashtary-Larky, D , Bagheri, R , et al. (2020) The effect of 12 weeks of equicaloric high protein diet in regulating appetite and body composition of women with Normal Weight Obesity: a randomized controlled trial. Br J Nutr 1–20. · DOI
  30. Chilibeck, 1997, A comparison of strength and muscle mass increases during resistance training in young women, Eur J Appl Physiol Occup Physiol, 77, 170, 10.1007/s004210050316 · DOI
  31. You, 2011, Adipose tissue endocannabinoid system gene expression: depot differences and effects of diet and exercise, Lipid Health Dis, 10, 194, 10.1186/1476-511X-10-194 · DOI
  32. Paoli, 2019, The influence of meal frequency and timing on health in humans: the role of fasting, Nutrients, 11, 719, 10.3390/nu11040719 · DOI · Paper page
  33. Yang, 1976, Composition of weight lost during short-term weight reduction. Metabolic responses of obese subjects to starvation and low-calorie ketogenic and nonketogenic diets, J Clin Investig, 58, 722, 10.1172/JCI108519 · DOI · Paper page
  34. 10.7717/peerj.6273 · DOI
  35. 10.1177/088307380101600901 · DOI
  36. Miller, 1996, Interrelationships among postprandial satiety, glucose and insulin responses and changes in subsequent food intake, Eur J Clin Nutr, 50, 788
  37. Cipryan, 2018, Effects of a 4-week very low-carbohydrate diet on high-intensity interval training responses, J Sports Sci Med, 17, 259
  38. 10.2337/db12-1208 · DOI
  39. 10.1038/ejcn.2013.90 · DOI · Paper page
  40. 10.1152/ajpendo.1990.259.4.E498 · DOI
  41. Johnston, 2017, Use of novel high-protein functional food products as part of a calorie-restricted diet to reduce insulin resistance and increase lean body mass in adults: a randomized controlled trial, Nutrients, 9, 1182, 10.3390/nu9111182 · DOI
  42. 10.1113/jphysiol.2001.012933 · DOI
  43. 10.1001/jama.2018.0245 · DOI · Paper page
  44. Klement, 2013, A pilot case study on the impact of a self-prescribed ketogenic diet on biochemical parameters and running performance in healthy and physically active individuals, Nutr Med, 1
  45. Willi, 1998, The effects of a high-protein, low-fat, ketogenic diet on adolescents with morbid obesity: body composition, blood chemistries, and sleep abnormalities, Pediatrics, 101, 61, 10.1542/peds.101.1.61 · DOI · Paper page
  46. Volek, 2004, Cardiovascular and hormonal aspects of very-low-carbohydrate ketogenic diets, Obes Res, 12, 115S, 10.1038/oby.2004.276 · DOI
  47. Crovetti, 1998, The influence of thermic effect of food on satiety, J Sports Sci, 52, 482
  48. 10.1111/obr.12241 · DOI
  49. 10.1152/ajpendo.1998.274.6.E1067 · DOI
  50. Zinn, 2017, Ketogenic diet benefits body composition and well-being but not performance in a pilot case study of New Zealand endurance athletes, J Int Soc Sports Nutr, 14, 22, 10.1186/s12970-017-0180-0 · DOI
  51. van Loon, 2011, Dietary Protein to Support Muscle Hypertrophy. Sports Nutrition: More Than Just Calories-Triggers for Adaptation
  52. Cardillo, 2006, The effects of a low-carbohydrate v. low-fat diet on adipocytokines in severely obese adults: three-year follow-up of a randomized trial, Eur Rev Med Pharmacol Sci, 10, 99
  53. Czech, 2017, Insulin action and resistance in obesity and type 2 diabetes, Nat Med, 23, 804, 10.1038/nm.4350 · DOI · Paper page
  54. Nehlig, 2004, Brain uptake and metabolism of ketone bodies in animal models, Prostaglandins Leukot Essent Fatty Acid, 70, 265, 10.1016/j.plefa.2003.07.006 · DOI
  55. Benoit, 1965, Changes in body composition during weight reduction in obesity: balance studies comparing effects of fasting and a ketogenic diet, Ann Intern Med, 63, 604, 10.7326/0003-4819-63-4-604 · DOI
  56. 10.1186/1550-2783-9-34 · DOI
  57. Perez-Guisado, 2011, The effect of the Spanish Ketogenic Mediterranean Diet on nonalcoholic fatty liver disease: a pilot study, J Med Food, 14, 677, 10.1089/jmf.2011.0075 · DOI
  58. Girard, 1985, Fatty acid oxidation and ketogenesis during development, Reprod Nutr Dév, 25, 303, 10.1051/rnd:19850221 · DOI
  59. 10.1271/bbb.60341 · DOI
  60. Yeo, 2011, Fat adaptation in well-trained athletes: effects on cell metabolism, Appl Physiol Nutr Metab, 36, 12, 10.1139/H10-089 · DOI · Paper page
  61. 10.1016/S0026-0495(00)90963-6 · DOI
  62. 10.1089/jmf.2016.0072 · DOI
  63. White, 2007, Blood ketones are directly related to fatigue and perceived effort during exercise in overweight adults adhering to low-carbohydrate diets for weight loss: a pilot study, J Am Dietetic Assoc, 107, 1792, 10.1016/j.jada.2007.07.009 · DOI
  64. Vargas, 2018, Efficacy of ketogenic diet on body composition during resistance training in trained men: a randomized controlled trial, J Int Soc Sports Nutr, 15, 31, 10.1186/s12970-018-0236-9 · DOI
  65. 10.1016/j.nutres.2020.02.010 · DOI
  66. Kiens, 1987, Lipoprotein lipase activity and intramuscular triglyceride stores after long-term high-fat and high-carbohydrate diets in physically trained men, Clin Physiol, 7, 1, 10.1111/j.1475-097X.1987.tb00628.x · DOI
  67. Noakes, 2013, The Real Meal Revolution
  68. Ashtary-Larky, 2018, Waist circumference to height ratio: better correlation with fat mass than other anthropometric indices during dietary weight loss in different rates, Int J Endocrinol Metab, 16, 10.5812/ijem.55023 · DOI
  69. 10.1186/1742-4682-4-27 · DOI
  70. Oh, 2020, Low Carbohydrate Diet. StatPearls
  71. 10.1016/j.pediatrneurol.2018.12.012 · DOI
  72. McDonald, 1998, The Ketogenic Diet: a Complete Guide for the Dieter and Practitioner
  73. 276. Sahagun, E , Bachman, BB , Kinzig, KP , et al. (2021) Sex-specific effects of ketogenic diet after pre-exposure to a high-fat, high-sugar diet in rats. Nutr Metab Cardiovasc Dis 31, 961–971. · DOI
  74. 10.1016/S0026-0495(99)90238-X · DOI · Paper page
  75. 10.1152/ajpendo.00674.2006 · DOI
  76. Kossoff, 2012, Ketogenic diets: new advances for metabolism-based therapies, Curr Opin Neurol, 25, 173, 10.1097/WCO.0b013e3283515e4a · DOI
  77. Dhillon, 2019, Biochemistry, Ketogenesis
  78. Manninen, 2004, Metabolic effects of the very-low-carbohydrate diets: misunderstood” villains” of human metabolism, J Soc Sport Nutr, 1, 1
  79. 10.1016/j.metabol.2010.09.007 · DOI
  80. 10.1093/ajcn/42.2.177 · DOI
  81. 10.1016/j.yebeh.2013.09.032 · DOI
  82. Fujita, 2009, Supraphysiological hyperinsulinaemia is necessary to stimulate skeletal muscle protein anabolism in older adults: evidence of a true age-related insulin resistance of muscle protein metabolism, Diabetologia, 52, 1889, 10.1007/s00125-009-1430-8 · DOI · Paper page
  83. Gyorkos, 2019, Carbohydrate-restricted diet and high-intensity interval training exercise improve cardio-metabolic and inflammatory profiles in metabolic syndrome: a randomized crossover trial, Cureus, 11, e5596
  84. 223. Ashtary Larky, D , Bagheri, R , Abbasnezhad, A , et al. (2020) Effects of gradual weight loss v. rapid weight loss on body composition and resting metabolic rate: a systematic review and meta-analysis. · DOI · Paper page
  85. 10.1038/s41598-019-56166-8 · DOI
  86. Joshi, 2019, The ketogenic diet for obesity and diabetes – enthusiasm outpaces evidence the ketogenic diet for obesity and diabetes: the ketogenic diet for obesity and diabetes, JAMA Internal Med, 179, 1163, 10.1001/jamainternmed.2019.2633 · DOI
  87. Jabekk, 2010, Resistance training in overweight women on a ketogenic diet conserved lean body mass while reducing body fat, Nutr Metab, 7, 17, 10.1186/1743-7075-7-17 · DOI · Paper page
  88. 10.1093/milmed/usz046 · DOI
  89. Fery, 1986, Response of ketone body metabolism to exercise during transition from postabsorptive to fasted state, Am J Physiology-Endocrinology Metab, 250, E495, 10.1152/ajpendo.1986.250.5.E495 · DOI
  90. Cameron-Smith, 2003, A short-term, high-fat diet up-regulates lipid metabolism and gene expression in human skeletal muscle, Am J Clin Nutr, 77, 313, 10.1093/ajcn/77.2.313 · DOI · Paper page
  91. 275. Salvador, AC , Arends, D , Barrington, WT , et al. (2021) Sex-specific genetic architecture in response to American and ketogenic diets. Int J Obes 1–14. · DOI
  92. 68. Levy, RG , Cooper, PN , Giri, P , et al. (2012) Ketogenic diet and other dietary treatments for epilepsy. · DOI · Paper page
  93. 10.1002/ana.20899 · DOI · Paper page
  94. Paoli, 2019, Ketogenic diet and skeletal muscle hypertrophy: a frenemy relationship?, J Hum Kinet, 68, 233, 10.2478/hukin-2019-0071 · DOI
  95. Wilson, 2017, The effects of ketogenic dieting on body composition, strength, power, and hormonal profiles in resistance training males, J Strength Condit Res, 34, 3463, 10.1519/JSC.0000000000001935 · DOI · Paper page
  96. 10.1200/JCO.2016.70.5327 · DOI
  97. 10.1016/j.molmet.2019.11.010 · DOI · Paper page
  98. 10.1016/j.nut.2016.03.003 · DOI
  99. 10.4103/1673-5374.241442 · DOI
  100. 10.1007/978-1-59259-808-3 · DOI
  101. 10.1177/0271678X16669366 · DOI · Paper page
  102. 10.1001/archinte.1920.00100060002001 · DOI
  103. Puglisi, 2019, Dietary Fat and Sports Performance. Nutrition and Enhanced Sports Performance
  104. Acheson, 1993, Influence of autonomic nervous system on nutrient-induced thermogenesis in humans, Nutrition, 9, 373
  105. Urbain, 2017, Impact of a 6-week non-energy-restricted ketogenic diet on physical fitness, body composition and biochemical parameters in healthy adults, Nutr Metab, 14, 17, 10.1186/s12986-017-0175-5 · DOI
  106. 10.3390/sports7010022 · DOI
  107. 110. Gaspari, A Scientific Review of Ketogenic Diet.
  108. Brinkworth, 2009, Effects of a low carbohydrate weight loss diet on exercise capacity and tolerance in obese subjects, Obesity, 17, 1916, 10.1038/oby.2009.134 · DOI · Paper page
  109. 10.1016/j.cct.2016.12.021 · DOI
  110. 10.1089/jmf.2010.0137 · DOI
  111. Yancy, 2004, A low-carbohydrate, ketogenic diet v. a low-fat diet to treat obesity and hyperlipidemia: a randomized, controlled trial, Ann Intern Med, 140, 769, 10.7326/0003-4819-140-10-200405180-00006 · DOI · Paper page
  112. Lu, 2018, Effects of low-fat compared with high-fat diet on cardiometabolic indicators in people with overweight and obesity without overt metabolic disturbance: a systematic review and meta-analysis of randomised controlled trials, Br J Nutr, 119, 96, 10.1017/S0007114517002902 · DOI · Paper page
  113. Wilder, 1921, The effects of ketonemia on the course of epilepsy, Mayo Clin Proc, 2, 307
  114. 10.1016/j.neurobiolaging.2019.09.015 · DOI
  115. Børsheim, 2004, Effect of carbohydrate intake on net muscle protein synthesis during recovery from resistance exercise, J Appl Physiol, 96, 674, 10.1152/japplphysiol.00333.2003 · DOI
  116. 10.1016/S0140-6736(69)90164-0 · DOI
  117. 10.1089/met.2011.0104 · DOI · Paper page
  118. 10.1016/S1474-4422(08)70092-9 · DOI · Paper page
  119. 10.3390/nu7115475 · DOI · Paper page
  120. Volek, 2002, Body composition and hormonal responses to a carbohydrate-restricted diet, Metab Clin Exp, 51, 864, 10.1053/meta.2002.32037 · DOI
  121. 10.1016/j.physbeh.2012.02.003 · DOI
  122. 10.1016/j.cmet.2016.07.010 · DOI · Paper page
  123. Ashtary-Larky, 2021, Effects of resistance training combined with a ketogenic diet on body cfomposition: a systematic review and meta-analysis, Crit Rev Food Sci Nutr, 1
  124. Jeukendrup, 2018, Sport Nutrition
  125. 10.1079/BJN19830066 · DOI
  126. 10.1159/000176515 · DOI
  127. Rhyu, 2014, The effect of weight loss by ketogenic diet on the body composition, performance-related physical fitness factors and cytokines of Taekwondo athletes, J Exerc Rehab, 10, 326, 10.12965/jer.140160 · DOI
  128. Going, 1993, Detection of small changes in body composition by dual-energy x-ray absorptiometry, Am J Clin Nutr, 57, 845, 10.1093/ajcn/57.6.845 · DOI
  129. 10.1016/j.biochi.2015.10.024 · DOI · Paper page
  130. 202. Widiatmaja, DM , Prabowo, GI & Rejeki, PS (2021) A Long-Term Ketogenic Diet Decreases Serum Insulin-Like Growth Factor-1 Levels in Mice. J Hunan Univ Nat Sci 48. · DOI
  131. Burke, 2011, Carbohydrates for training and competition, J Sport Sci, 29, S17, 10.1080/02640414.2011.585473 · DOI · Paper page
  132. 10.1152/japplphysiol.00126.2016 · DOI
  133. Gomez-Arbelaez, 2018, Resting metabolic rate of obese patients under very low calorie ketogenic diet, Nutr Metab, 15, 18, 10.1186/s12986-018-0249-z · DOI
  134. 10.1152/ajpendo.00268.2005 · DOI · Paper page
  135. 10.1249/JES.0000000000000053 · DOI
  136. Bielohuby, 2011, Lack of dietary carbohydrates induces hepatic growth hormone (GH) resistance in rats, Endocrinology, 152, 1948, 10.1210/en.2010-1423 · DOI
  137. 10.3390/sports7020040 · DOI
  138. 10.1016/S0749-0720(15)30102-X · DOI · Paper page
  139. Rui, 2011, Energy metabolism in the liver, Compr Physiol, 4, 177
  140. Goedecke, 1999, Metabolic adaptations to a high-fat diet in endurance cyclists, Metabolism, 48, 1509, 10.1016/S0026-0495(99)90238-X · DOI · Paper page
  141. Ma, 2018, An 8-week ketogenic diet alternated interleukin-6, ketolytic and lipolytic gene expression, and enhanced exercise capacity in mice, Nutrients, 10, 1696, 10.3390/nu10111696 · DOI
  142. 10.1080/07315724.2004.10719381 · DOI · Paper page
  143. Perez-Guisado, 2008, Spanish Ketogenic Mediterranean Diet: a healthy cardiovascular diet for weight loss, Nutr J, 7, 30, 10.1186/1475-2891-7-30 · DOI
  144. Ashtary-Larky, 2018, Relationship between the body fat percentage and anthropometric measurements in athletes compared with non-athletes, Zahedan J Res Med Sci, 20, e10422, 10.5812/zjrms.10422 · DOI
  145. Ahola-Erkkilä, 2010, Ketogenic diet slows down mitochondrial myopathy progression in mice, Hum Mol Gen, 19, 1974, 10.1093/hmg/ddq076 · DOI
  146. 10.1016/j.clnu.2011.09.012 · DOI
  147. Urbain, 2017, Impact of a 6-week non-energy-restricted ketogenic diet on physical fitness, body composition and biochemical parameters in healthy adults, Nutr Metab, 14, 17, 10.1186/s12986-017-0175-5 · DOI
  148. 10.1111/j.1528-1167.2011.02981.x · DOI · Paper page
  149. 10.1016/j.cmet.2013.12.008 · DOI · Paper page
  150. 10.1186/1743-7075-3-7 · DOI
  151. 10.1016/j.clnu.2009.08.015 · DOI
  152. 10.3390/ijerph110202092 · DOI · Paper page
  153. 10.1186/1550-2783-1-2-21 · DOI
  154. 10.3945/ajcn.2009.27834 · DOI · Paper page
  155. 10.1016/S0195-6663(95)80005-0 · DOI
  156. 10.1161/JAHA.116.005066 · DOI
  157. 10.1152/ajpendo.00397.2012 · DOI · Paper page
  158. D’Andrea-Meira, 2019, Ketogenic diet and epilepsy: what we know so far, Front Neurosci, 13, 5, 10.3389/fnins.2019.00005 · DOI · Paper page
  159. 10.1016/S0002-9149(01)01586-7 · DOI
  160. 10.1007/s12603-020-1431-3 · DOI
  161. 10.1093/ajcn/24.3.290 · DOI
  162. Schrauwen, 2000, Increase in fat oxidation on a high-fat diet is accompanied by an increase in triglyceride-derived fatty acid oxidation, Diabetes, 49, 640, 10.2337/diabetes.49.4.640 · DOI
  163. 10.1007/s00421-015-3175-z · DOI
  164. 10.3945/ajcn.111.025270 · DOI
  165. 10.1038/s41591-019-0643-8 · DOI · Paper page
  166. 10.1159/000176222 · DOI
  167. Johnson, 1971, Fitness, fatness, and post-exercise ketosis, Lancet, 297, 566, 10.1016/S0140-6736(71)91164-0 · DOI
  168. Gu, 2013, Beneficial effects of an 8-week, very low carbohydrate diet intervention on obese subjects, Evid base Compl Alternative Med, 2013, 760804
  169. 10.1519/00124278-200702000-00037 · DOI
  170. 10.1002/ana.20899 · DOI · Paper page
  171. Muscogiuri, 2019, The management of very low-calorie ketogenic diet in obesity outpatient clinic: a practical guide, J Transl Med, 17, 356, 10.1186/s12967-019-2104-z · DOI · Paper page
  172. Paoli, 2010, Ketogenic diet and phytoextracts Comparison of the efficacy of Mediterranean, zone and tisanoreica diet on some health risk factors, Agro Food Ind Hi-Tech, 21, 24
  173. Masood, 2019, Ketogenic Diet. StatPearls
  174. Sawyer, 2013, Effects of a short-term carbohydrate-restricted diet on strength and power performance, J Strength Cond Res, 27, 2255, 10.1519/JSC.0b013e31827da314 · DOI
  175. 10.1155/2018/5157645 · DOI
  176. 10.5114/biolsport.2020.98448 · DOI
  177. 10.1016/j.ebiom.2019.08.032 · DOI · Paper page
  178. Draznin, 2012, Effect of dietary macronutrient composition on AMPK and SIRT1 expression and activity in human skeletal muscle, Hormone Metab Res, 44, 650, 10.1055/s-0032-1312656 · DOI
  179. 10.1037/0278-6133.4.1.1 · DOI
  180. Manninen, 2006, Very-low-carbohydrate diets and preservation of muscle mass, Nutr Metab, 3, 1, 10.1186/1743-7075-3-9 · DOI
  181. 10.1152/jappl.1997.82.6.1882 · DOI
  182. 10.1152/jappl.2000.88.2.386 · DOI · Paper page
  183. 10.23937/2469-5718/1510054 · DOI
  184. Dostal, 2019, Effects of a 12-week very-low carbohydrate high-fat diet on maximal aerobic capacity, high-intensity intermittent exercise, and cardiac autonomic regulation: non-randomized parallel-group study, Front Physiol, 10, 912, 10.3389/fphys.2019.00912 · DOI
  185. 10.1016/S0197-0186(00)00102-9 · DOI
  186. Greenhaff, 2008, Disassociation between the effects of amino acids and insulin on signaling, ubiquitin ligases, and protein turnover in human muscle, Am J Physiol-Endocrinol Metab, 295, E595, 10.1152/ajpendo.90411.2008 · DOI · Paper page
  187. 10.1016/j.jsams.2018.12.015 · DOI · Paper page
  188. Kang, 2020, Ergogenic properties of ketogenic diets in normal-weight individuals: a systematic review, J Am Coll Nutr, 39, 665, 10.1080/07315724.2020.1725686 · DOI
  189. Pozefsky, 1976, Effects of brief starvation on muscle amino acid metabolism in nonobese man, J Clin Investig, 57, 444, 10.1172/JCI108295 · DOI
  190. Dopler Nelson, 2010, Genetic phenotypes predict weight loss success: The right diet does matter, 50th Cardiovasc Dis Epidemiol Prev Nutr, Phys Activity Metab, 79
  191. Fraser, 2000, Reduction in serum leptin and IGF-1 but preserved T-lymphocyte numbers and activation after a ketogenic diet in rheumatoid arthritis patients, Clin Exp Rheumatol, 18, 209
  192. Boyd, 1974, Lactate inhibition of lipolysis in exercising man, Metabolism, 23, 531, 10.1016/0026-0495(74)90081-X · DOI
  193. Koeslag, 1980, Post-exercise ketosis, J Physiol, 301, 79, 10.1113/jphysiol.1980.sp013190 · DOI
  194. Paoli, 2010, Ketogenic diet and phytoextracts, Sci Advisory Board, 21, 24
  195. Puchalska, 2017, Multi-dimensional roles of ketone bodies in fuel metabolism, signaling, and therapeutics, Cell Metab, 25, 262, 10.1016/j.cmet.2016.12.022 · DOI · Paper page
  196. Tipton, 2001, Timing of amino acid-carbohydrate ingestion alters anabolic response of muscle to resistance exercise, Am J Physiol-Endocrinol Metab, 10.1152/ajpendo.2001.281.2.E197 · DOI · Paper page
  197. 10.1093/med/9780190497996.001.0001 · DOI
  198. 10.3390/nu11051156 · DOI
  199. 10.1152/ajpendo.00305.2020 · DOI
  200. 10.1017/S0007114513000548 · DOI · Paper page

200 of 270 shown

Cited by

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Metadata

Authors
Ashtary-Larky, D., Bagheri, R., Bavi, H., Baker, J. S., Moro, T., Mancin, L., & Paoli, A.
ORCID
Moro, Tatiana
Venue
British Journal of Nutrition
Publisher
Cambridge University Press (CUP)
Published
2021-07-12
Volume
127
Issue
12
Pages
1898-1920
ISSN
  • 0007-1145
  • 1475-2662
DOI
10.1017/s0007114521002609
PMC
PMC9244428
Cited by
100
References
111
Language
en
Licence
creativecommons.org/licenses/by/4.0/ (unspecified)

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

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Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.