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Can impaired working memory functioning be improved by training? A meta-analysis with a special focus on brain injured patients.
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OBJECTIVE: Deficits in working memory (WM) are commonly observed after brain injuries and cause severe impairments in patients' everyday life. It is still under debate if training can enhance or rehabilitate WM in case of malfunction. The current meta-analysis investigates this issue from a clinical point of view. It addresses under which conditions and for which target group WM training may be justifiable. METHOD: Relevant WM training studies were identified by searching electronic literature databases with a comprehensive search term. In total, 103 studies, which added up to 112 independent group comparisons (N = 6,113 participants), were included in the analysis. RESULTS: Overall, WM training caused a moderate and long-lasting improvement in untrained WM tasks. Moreover, improvement of WM functioning led to sustainable better evaluation of everyday life functioning, however, effect sizes were small. Concerning transfer effects on other cognitive domains, long-lasting improvements with small effect sizes were observed in cognitive control and reasoning/intelligence. In contrast, small immediate, but no long-term effects were found for attention and long-term memory. Studies with brain injured patients demonstrated long-lasting improvements in WM functions with moderate to large effect sizes. A main moderator variable of intervention efficacy is the number of training sessions applied. CONCLUSION: WM training produces long-lasting beneficial effects which are strongly pronounced in patients with acquired brain injuries. This finding supports the application of WM training in clinical settings. To determine optimal training conditions, future studies must systematically investigate the characteristics of interventions as they are at present inevitably confounded.
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Løhaugen, G. C. C., Antonsen, I. K., Haberg, A. K., Gramstad, A., Vik, T., Brubakk, A., & Skranes, J. S. (2010) · The Journal of Pediatrics · doi:10.1016/j.jpeds.2010.09.060 · Cited by 131
Bennett, S., Holmes, J., & Buckley, S. (2013) · American Journal on Intellectual and Developmental Disabilities · doi:10.1352/1944-7558-118.3.179 · Cited by 130
Söderqvist, S., Nutley, S. B., Ottersen, J., Grill, K. M., & Klingberg, T. (2012) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2012.00271 · Cited by 127
Jolles, D. D., Grol, M. J., Van Buchem, M. A., Rombouts, S. A. R. B., & Crone, E. A. (2010) · NeuroImage · doi:10.1016/j.neuroimage.2010.04.028 · Cited by 122
Effects of working memory training in young and old adults
von Bastian, C. C., Langer, N., Jäncke, L., & Oberauer, K. (2012) · Memory & Cognition · doi:10.3758/s13421-012-0280-7 · Cited by 120
Influence of neuroticism and conscientiousness on working memory training outcome
Studer-Luethi, B., Jaeggi, S. M., Buschkuehl, M., & Perrig, W. J. (2012) · Personality and Individual Differences · doi:10.1016/j.paid.2012.02.012 · Cited by 117
The effects of working memory resource depletion and training on sensorimotor adaptation
Anguera, J. A., Bernard, J. A., Jaeggi, S. M., Buschkuehl, M., Benson, B. L., Jennett, S., Humfleet, J., Reuter-Lorenz, P. A., Jonides, J., & Seidler, R. D. (2012) · Behavioural Brain Research · doi:10.1016/j.bbr.2011.11.040 · Cited by 115
Working Memory Training Improves Cognitive Function in VLBW Preschoolers
Grunewaldt, K. H., Løhaugen, G. C. C., Austeng, D., Brubakk, A., & Skranes, J. S. (2013) · PEDIATRICS · doi:10.1542/peds.2012-1965 · Cited by 113
Colom, R., Román, F. J., Abad, F. J., Shih, P. C., Privado, J., Froufe, M., Escorial, S., Martínez, K., Burgaleta, M., Quiroga, M. A., et al. (2013) · Intelligence · doi:10.1016/j.intell.2013.09.002 · Cited by 112
Dual n-back training increases the capacity of the focus of attention
Lilienthal, L., Tamez, E., Shelton, J. T., Myerson, J., & Hale, S. (2013) · Psychonomic Bulletin & Review · doi:10.3758/s13423-012-0335-6 · Cited by 112
Can intelligence be increased by training on a task of working memory?
Moody, D. E. (2009) · Intelligence · doi:10.1016/j.intell.2009.04.005 · Cited by 104
Åkerlund, E., Esbjörnsson, E., Sunnerhagen, K. S., & Björkdahl, A. (2013) · Brain Injury · doi:10.3109/02699052.2013.830195 · Cited by 103
Potentials and Limits of Plasticity Induced by Working Memory Training in Old-Old Age
Zinke, K., Zeintl, M., Eschen, A., Herzog, C., & Kliegel, M. (2011) · Gerontology · doi:10.1159/000324240 · Cited by 102
Gains in language comprehension relating to working memory training in healthy older adults
Carretti, B., Borella, E., Zavagnin, M., & Béni, R. D. (2012) · International Journal of Geriatric Psychiatry · doi:10.1002/gps.3859 · Cited by 101
Benefits of training visuospatial working memory in young-old and old-old.
Borella, E., Carretti, B., Cantarella, A., Riboldi, F., Zavagnin, M., & De Beni, R. (2014) · Developmental Psychology · doi:10.1037/a0034293 · Cited by 101
Stepankova, H., Lukavsky, J., Buschkuehl, M., Kopecek, M., Ripova, D., & Jaeggi, S. M. (2014) · Developmental Psychology · doi:10.1037/a0034913 · Cited by 101
Working Memory Training in Old Age: An Examination of Transfer and Maintenance Effects
Borella, E., Carretti, B., Zanoni, G., Zavagnin, M., & Béni, R. D. (2013) · Archives of Clinical Neuropsychology · doi:10.1093/arclin/act020 · Cited by 100
Publication Bias in Recent Meta-Analyses
Kiciński, M. (2013) · PLoS ONE · doi:10.1371/journal.pone.0081823 · Cited by 99
Working memory training for patients with acquired brain injury: effects in daily life
Johansson, B., & Tornmalm, M. (2011) · Scandinavian Journal of Occupational Therapy · doi:10.3109/11038128.2011.603352 · Cited by 97
Rehabilitation of verbal working memory after left hemisphere stroke
Vallat‐Azouvi, C., Azouvi, P., Hardisson, H., et al. (2005) · Brain Injury · doi:10.1080/02699050500110595 · Cited by 97
Training working memory: Limits of transfer
Sprenger, A. M., Atkins, S. M., Bolger, D. J., Harbison, J. I., Novick, J. M., Chrabaszcz, J. S., Weems, S. A., Smith, V., Bobb, S., Bunting, M. F., et al. (2013) · Intelligence · doi:10.1016/j.intell.2013.07.013 · Cited by 96
Training of the executive component of working memory: Subcortical areas mediate transfer effects
Dahlin, E., Bäckman, L., Neely, A. S., & Nyberg, L. H. (2009) · Restorative Neurology and Neuroscience · doi:10.3233/rnn-2009-0492 · Cited by 95
Rudebeck, S. R., Bor, D., Ormond, A., O’Reilly, J. X., & Lee, A. C. H. (2012) · PLoS ONE · doi:10.1371/journal.pone.0050431 · Cited by 95
Working memory after severe traumatic brain injury
Vallat‐Azouvi, C., WEBER, T., LEGRAND, L., & Azouvi, P. (2007) · Journal of the International Neuropsychological Society · doi:10.1017/s1355617707070993 · Cited by 91
The impact of auditory working memory training on the fronto-parietal working memory network
Schneiders, J. A., Opitz, B., Tang, H., Deng, Y., Xie, C., Li, H., & Mecklinger, A. (2012) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2012.00173 · Cited by 91
Expectancy effect: Impact of pill administration on cognitive performance in healthy seniors
Oken, B., Flegal, K. E., Zajdel, D. P., Kishiyama, S. S., Haas, M., & Peters, D. (2007) · Journal of Clinical and Experimental Neuropsychology · doi:10.1080/13803390701775428 · Cited by 89
A pilot study of combined working memory and inhibition training for children with AD/HD
Johnstone, S. J., Roodenrys, S., Phillips, E., Watt, A. J., & Mantz, S. (2010) · ADHD Attention Deficit and Hyperactivity Disorders · doi:10.1007/s12402-009-0017-z · Cited by 84
Training Working Memory to Reduce Rumination
Onraedt, T., & Koster, E. H. W. (2014) · PLoS ONE · doi:10.1371/journal.pone.0090632 · Cited by 84
Working memory plasticity modulated by dopamine transporter genotype
Brehmer, Y., Westerberg, H., Bellander, M., Fürth, D., Karlsson, S., & Bäckman, L. (2009) · Neuroscience Letters · doi:10.1016/j.neulet.2009.10.018 · Cited by 80
Is Working Memory Training Effective? A Study in a School Setting
Rode, C., Robson, R., Purviance, A., Geary, D. C., & Mayr, U. (2014) · PLoS ONE · doi:10.1371/journal.pone.0104796 · Cited by 76
Witt, M. (2011) · Advances in Cognitive Psychology · doi:10.2478/v10053-008-0083-3 · Cited by 75
Working Memory Updating Function Training Influenced Brain Activity
Zhao, X., Zhou, R., & Fu, L. (2013) · PLoS ONE · doi:10.1371/journal.pone.0071063 · Cited by 75
Carretti, B., Borella, E., Fostinelli, S., & Zavagnin, M. (2012) · International Psychogeriatrics · doi:10.1017/s1041610212002177 · Cited by 74
An Evaluation of a Working Memory Training Scheme in Older Adults
McAvinue, L. P., Golemme, M., Castorina, M., Tatti, E., Pigni, F. M., Salomone, S., Brennan, S., & Robertson, I. H. (2013) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2013.00020 · Cited by 74
RCT of Working Memory Training in ADHD: Long-Term Near-Transfer Effects
Hovik, K. T., Saunes, B.-K., Aarlien, A. K., & Egeland, J. (2013) · PLoS ONE · doi:10.1371/journal.pone.0080561 · Cited by 74
The structure of head-injured patients' neurobehavioural complaints: A preliminary study
Hinkeldey, N. S., & Corrigan, J. D. (1990) · Brain Injury · doi:10.3109/02699059009026157 · Cited by 73
Henry, L. A., Messer, D. J., & Nash, G. (2014) · Infant and Child Development · doi:10.1002/icd.1816 · Cited by 72
Shiran, A., & Breznitz, Z. (2011) · Journal of Neurolinguistics · doi:10.1016/j.jneuroling.2010.12.001 · Cited by 71
Gibson, B. S., Gondoli, D. M., Johnson, A. C., Steeger, C. M., Dobrzenski, B. A., & Morrissey, R. A. (2011) · Child Neuropsychology · doi:10.1080/09297049.2010.551186 · Cited by 71
Working Memory Training in College Students With ADHD or LD
Gropper, R. J., Gotlieb, H., Kronitz, R., & Tannock, R. (2014) · Journal of Attention Disorders · doi:10.1177/1087054713516490 · Cited by 67
Can interactive working memory training improving learning
Alloway, T. P. (2012) · University of North Florida Digital Commons (University of North Florida) · Cited by 62
Penner, I.-K., Vogt, A., Stöcklin, M., Gschwind, L., Opwis, K., & Calabrese, P. (2012) · Neuropsychological Rehabilitation · doi:10.1080/09602011.2012.686883 · Cited by 60
Cognitive Ability: Does Working Memory Training Enhance Intelligence?
Conway, A. R. A., & Getz, S. J. (2010) · Current Biology · doi:10.1016/j.cub.2010.03.001 · Cited by 48
Bellander, M., Brehmer, Y., Westerberg, H., Karlsson, S., Fürth, D., Bergman, O., Eriksson, E., & Bäckman, L. (2011) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2011.03.021 · Cited by 48
Gibson, B. S., Kronenberger, W. G., Gondoli, D. M., Johnson, A. C., Morrissey, R. A., & Steeger, C. M. (2012) · Journal of Applied Research in Memory and Cognition · doi:10.1016/j.jarmac.2012.06.005 · Cited by 44
Goverover, Y., Arango‐Lasprilla, J. C., Hillary, F. G., Chiaravalloti, N. D., & DeLuca, J. (2009) · American Journal of Occupational Therapy · doi:10.5014/ajot.63.5.543 · Cited by 37
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Zimmermann, N., Netto, T. M., Amodeo, M. T., Ska, B., & Fonseca, R. P. (2014) · Neurorehabilitation · doi:10.3233/nre-141104 · Cited by 23
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Self-citation
Flagged first, then by citations
Research works printed but not linked: 4
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Cited by
Sorted by citations
Melby-Lervåg, M., Redick, T. S., & Hulme, C. (2016) · Perspectives on Psychological Science · doi:10.1177/1745691616635612 · Cited by 983
“For example, whether an active control group uses a nonadaptive training regime or a different, adaptive activity may have effects (Weicker et al., 2016).”
Wise interventions: Psychological remedies for social and personal problems.
Walton, G. M., & Wilson, T. D. (2018) · Psychological Review · doi:10.1037/rev0000115 · Cited by 617
Working memory training revisited: A multi-level meta-analysis of n-back training studies
Soveri, A., Antfolk, J., Karlsson, L., Salo, B., & Laine, M. (2017) · Psychonomic Bulletin & Review · doi:10.3758/s13423-016-1217-0 · Cited by 371
“…to cognitive control (Melby-Lervåg & Hulme, 2013; Weicker et al., 2016) and attention (Weicker et al., 2016), but no transfer to long-term memory (Weicker et al., 2016), arithmetic skills (Melby-Lervåg & Hulme, 2013; Ta bl e 1 Su m m ar y of th e re su lts fr om pr ev io us m et aan al ys es in…”
BackgroundMethodResultInfluentialWorking memory training involves learning new skills
Gathercole, S. E., Dunning, D. L., Holmes, J., & Norris, D. (2019) · Journal of Memory and Language · doi:10.1016/j.jml.2018.10.003 · Cited by 225
Working memory training in typically developing children: A meta-analysis of the available evidence.
Sala, G., & Gobet, F. (2017) · Developmental Psychology · doi:10.1037/dev0000265 · Cited by 216
Metadata
- Authors
- Weicker, J., Villringer, A., & Thöne-Otto, A.
- Affiliations
- Max Planck Society (DE)
- Leipzig University (DE)
- Venue
- Neuropsychology
- Published
- 2016
- Volume
- 30
- Issue
- 2
- Pages
- 190-212
- ISSN
- 0894-4105 (ISSN-L)
- 1931-1559
- OpenAlex
- W1618038909
- Semantic Scholar
- 1016f832cb994fa36bd96a515015eb5bacbd71e9
- Cited by
- 147
- References
- 164
- Citations by year
- 2026: 2 · 2025: 10 · 2024: 8 · 2023: 6 · 2022: 10 · 2021: 17 · 2020: 16 · 2019: 27 · 2018: 20 · 2017: 21 · 2016: 9
- FWCI
- 25.60
- Type
- journal article
- Language
- en
- Open access
- green
- ul.qucosa.de
- Licence
- cc-by-nc-nd
- Locations
- Neuropsychology (publishedVersion)
- PubMed (publishedVersion)
- MPG.PuRe (Max Planck Society) (submittedVersion)
- Qucosa (Saxon State and University Library Dresden) (submittedVersion, cc-by-nc-nd)
- Funders
- German Max Planck Society
- Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Cognitive Abilities and Testing
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Cognitive Functions and Memory
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Keywords
- working memory training, working memory, brain injury, acquired brain injury, cognitive rehabilitation, transfer effects, cognitive control, attention, long-term memory, training sessions
- MeSH terms
- Attention, Brain Injuries, Humans, Intelligence, Learning, Memory, Short-Term, Thinking, Memory, Long-Term
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