Early life adversity and adult social behavior: focus on arginine vasopressin and oxytocin as potential mediators
Open accessAbstract
Exposure to stress during the early postnatal period (i.e., early life stress, ES) can impact brain physiology and modify individual variability in adult social behavior. Arginine vasopressin (AVP) and oxytocin (OXT) are two centrally released neuropeptides that are involved in shaping essential social behaviors, like aggression, social recognition, and social motivation. AVP and OXT modulate activity in brain regions important for the establishment of social behavior, and may be particularly sensitive to ES. In this review, we discuss whether ES alters the characteristics of the AVP- and OXT- systems in rodents, and whether these changes are associated with later alterations in aggression, social recognition, and social motivation. We have integrated causal studies indicating that (1) ES affects AVP/OXT, and (2) that changing AVP/OXT in affected regions alters social behavior. Although there is encouraging evidence that ES causes AVP- and OXT-system changes, and that these may mediate social behavior, a comprehensive understanding of the exact nature of AVP- and OXT changes and whether they are causal in establishing these behavioral disturbances needs further investigation. As there are indications that ES alters AVP- and OXT characteristics in humans as well, and that these may interact with adult predisposition to psychopathology with social dysfunction, future rodent studies may lay ground for a better understanding of such changes in humans. Ultimately, this may assist in developing therapeutic strategies to target ES effects on social behavior.
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Early life stress significantly impacted the oxytocinergic system in brain regions associated with social behavior, suggesting similar connections in humans.
“Integrating causal animal studies, the researchers found that early life stress significantly impacted the oxytocinergic system in brain regions associated with social behavior and suggested similar connections in humans.”
From The evolved nest, oxytocin functioning, and prosocial development (2023) · cites this paper as Kompier et al. (2019)
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Cites
Oxytocin increases trust in humans
Kosfeld, M., Heinrichs, M., Zak, P. J., Fischbacher, U., & Fehr, E. (2005) · Nature · doi:10.1038/nature03701 · Cited by 3,690 · see citing works
The oxytocin receptor system: structure, function, and regulation
Gimpl, G., & Fahrenholz, F. (2001) · Physiological Reviews · doi:10.1152/physrev.2001.81.2.629 · Cited by 3,089 · see citing works
The social motivation theory of autism
Chevallier, C., Kohls, G., Troiani, V., Brodkin, E. S., & Schultz, R. T. (2012) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2012.02.007 · Cited by 2,072 · see citing works
Edwards, V. J., Holden, G. W., Felitti, V. J., & Anda, R. F. (2003) · American Journal of Psychiatry · doi:10.1176/appi.ajp.160.8.1453 · Cited by 1,832 · see citing works
Oxytocin and vasopressin in the human brain: social neuropeptides for translational medicine
Meyer-Lindenberg, A., Domes, G., Kirsch, P., & Heinrichs, M. (2011) · Nature Reviews Neuroscience · doi:10.1038/nrn3044 · Cited by 1,688 · see citing works
Plotsky, P. M., & Meaney, M. J. (1993) · Molecular Brain Research · doi:10.1016/0169-328x(93)90189-v · Cited by 1,638 · see citing works
Read, J., van Os, J., Morrison, A. P., & Ross, C. A. (2005) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.2005.00634.x · Cited by 1,534 · see citing works
The neurobiological consequences of early stress and childhood maltreatment
Teicher, M. H., Andersen, S. L., Polcari, A., Anderson, C. M., Navalta, C. P., & Kim, D. M. (2003) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(03)00007-1 · Cited by 1,465 · see citing works
Dynamic DNA methylation programs persistent adverse effects of early-life stress
Murgatroyd, C., Patchev, A. V., Wu, Y., Micale, V., Bockmühl, Y., Fischer, D., Holsboer, F., Wotjak, C. T., Almeida, O. F. X., & Spengler, D. (2009) · Nature Neuroscience · doi:10.1038/nn.2436 · Cited by 1,162 · see citing works
Social reward requires coordinated activity of nucleus accumbens oxytocin and serotonin
Dölen, G., Darvishzadeh, A., Huang, K. W., & Malenka, R. C. (2013) · Nature · doi:10.1038/nature12518 · Cited by 1,161 · see citing works
Oxytocin in the Medial Amygdala is Essential for Social Recognition in the Mouse
Ferguson, J. N., Aldag, J. M., Insel, T. R., & Young, L. J. (2001) · The Journal of Neuroscience · doi:10.1523/jneurosci.21-20-08278.2001 · Cited by 1,043 · see citing works
Heim, C., & Binder, E. B. (2012) · Experimental Neurology · doi:10.1016/j.expneurol.2011.10.032 · Cited by 986 · see citing works
Dendritic peptide release and peptide-dependent behaviours
Ludwig, M., & Leng, G. (2006) · Nature Reviews Neuroscience · doi:10.1038/nrn1845 · Cited by 945 · see citing works
Promoting social behavior with oxytocin in high-functioning autism spectrum disorders.
Andari, E., Duhamel, J.-R., Zalla, T., Herbrecht, E., Leboyer, M., & Sirigu, A. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0910249107 · Cited by 941 · see citing works
Oxytocin and the Neural Mechanisms Regulating Social Cognition and Affiliative Behavior
Ross, H. E., & Young, L. J. (2009) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2009.05.004 · Cited by 856 · see citing works
Hein, G., Silani, G., Preuschoff, K., Batson, C. D., & Singer, T. (2010) · Neuron · doi:10.1016/j.neuron.2010.09.003 · Cited by 821 · see citing works
Oxytocin, vasopressin, and human social behavior
Heinrichs, M., von Dawans, B., & Domes, G. (2009) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2009.05.005 · Cited by 799 · see citing works
Blair, J. (2001) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.71.6.727 · Cited by 710 · see citing works
Oxytocin Increases Retention of Social Cognition in Autism
Hollander, E., Bartz, J., Chaplin, W., Phillips, A., Sumner, J., Soorya, L., Anagnostou, E., & Wasserman, S. (2007) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.05.030 · Cited by 693 · see citing works
Stress and the social brain: behavioural effects and neurobiological mechanisms
Sandi, C., & Haller, J. (2015) · Nature reviews. Neuroscience · doi:10.1038/nrn3918 · Cited by 614 · see citing works
Research Review: The neurobiology and genetics of maltreatment and adversity
McCrory, E., De Brito, S. A., & Viding, E. (2010) · Journal of Child Psychology and Psychiatry · doi:10.1111/j.1469-7610.2010.02271.x · Cited by 598 · see citing works
Fries, A. B. W., Ziegler, T. E., Kurian, J. R., Jacoris, S., & Pollak, S. D. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0504767102 · Cited by 570 · see citing works
Morgan, C., & Fisher, H. (2006) · Schizophrenia Bulletin · doi:10.1093/schbul/sbl053 · Cited by 568 · see citing works
(2004) · PubMed · Cited by 567 · see citing works
Bielsky, I. F., Hu, S.-B., Szegda, K. L., Westphal, H., & Young, L. J. (2004) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300360 · Cited by 531 · see citing works
A Novel Mouse Model for Acute and Long-Lasting Consequences of Early Life Stress
Rice, C. J., Sandman, C. A., Lenjavi, M. R., & Baram, T. Z. (2008) · Endocrinology · doi:10.1210/en.2008-0633 · Cited by 521 · see citing works
Lower CSF oxytocin concentrations in women with a history of childhood abuse
Heim, C., Young, L. J., Newport, D. J., Mletzko, T., Miller, A. H., & Nemeroff, C. B. (2009) · Molecular Psychiatry · doi:10.1038/mp.2008.112 · Cited by 518 · see citing works
Neuromodulation by Oxytocin and Vasopressin
Stoop, R. (2012) · Neuron · doi:10.1016/j.neuron.2012.09.025 · Cited by 506 · see citing works
Vasopressin: Behavioral roles of an “original” neuropeptide
Caldwell, H. K., Lee, H.-J., Macbeth, A. H., & Young, W. S. (2008) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2007.10.007 · Cited by 504 · see citing works
The neuroendocrine basis of social recognition
Ferguson, J. N., Young, L. J., & Insel, T. R. (2002) · Frontiers in Neuroendocrinology · doi:10.1006/frne.2002.0229 · Cited by 494 · see citing works
Oxytocin can hinder trust and cooperation in borderline personality disorder
Bartz, J., Simeon, D., Hamilton, H., Kim, S., Crystal, S., Braun, A., Vicens, V., & Hollander, E. (2011) · Social Cognitive and Affective Neuroscience · doi:10.1093/scan/nsq085 · Cited by 452 · see citing works
Childhood origins of antisocial behavior
Farrington, D. P. (2005) · Clinical Psychology & Psychotherapy · doi:10.1002/cpp.448 · Cited by 447 · see citing works
Brain Oxytocin Correlates with Maternal Aggression: link to Anxiety
Bosch, O. J., Meddle, S. L., Beiderbeck, D. I., Douglas, A. J., & Neumann, I. D. (2005) · The Journal of Neuroscience · doi:10.1523/jneurosci.1342-05.2005 · Cited by 439 · see citing works
The Role of m6A/m-RNA Methylation in Stress Response Regulation
Engel, M., Eggert, C., Kaplick, P. M., Eder, M., Röh, S., Tietze, L., Namendorf, C., Arloth, J., Weber, P., Rex-Haffner, M., et al. (2018) · Neuron · doi:10.1016/j.neuron.2018.07.009 · Cited by 411 · see citing works
Lukas, M., Toth, I., Reber, S. O., Slattery, D. A., Veenema, A. H., & Neumann, I. D. (2011) · Neuropsychopharmacology · doi:10.1038/npp.2011.95 · Cited by 403 · see citing works
Oxytocin Makes a Face in Memory Familiar
Rimmele, U., Hediger, K., Heinrichs, M., & Klaver, P. (2009) · The Journal of Neuroscience · doi:10.1523/jneurosci.4260-08.2009 · Cited by 402 · see citing works
Bosch, O. J., & Neumann, I. D. (2012) · Hormones and Behavior · doi:10.1016/j.yhbeh.2011.11.002 · Cited by 400 · see citing works
Cerebrospinal Fluid Vasopressin Levels
Coccaro, E. F., Kavoussi, R. J., Hauger, R. L., Cooper, T. B., & Ferris, C. F. (1998) · Archives of General Psychiatry · doi:10.1001/archpsyc.55.8.708 · Cited by 392 · see citing works
The Resident-intruder Paradigm: A Standardized Test for Aggression, Violence and Social Stress
Koolhaas, J. M., Coppens, C. M., de Boer, S. F., Buwalda, B., Meerlo, P., & Timmermans, P. J. A. (2013) · Journal of Visualized Experiments · doi:10.3791/4367 · Cited by 391 · see citing works
Loup, F., Tribollet, E., Dubois-Dauphin, M., & Dreifuss, J. J. (1991) · Brain Research · doi:10.1016/0006-8993(91)90345-v · Cited by 378 · see citing works
Baskerville, T. A., & Douglas, A. J. (2010) · CNS Neuroscience & Therapeutics · doi:10.1111/j.1755-5949.2010.00154.x · Cited by 377 · see citing works
Developmental consequences of oxytocin
Carter, C. S. (2003) · Physiology & Behavior · doi:10.1016/s0031-9384(03)00151-3 · Cited by 367 · see citing works
Bielsky, I. F., Hu, S.-B., Ren, X., Terwilliger, E. F., & Young, L. J. (2005) · Neuron · doi:10.1016/j.neuron.2005.06.031 · Cited by 367 · see citing works
Oxytocin enhances social recognition by modulating cortical control of early olfactory processing
Oettl, L.-L., Ravi, N., Schneider, M., Scheller, M. F., Schneider, P., Mitre, M., da Silva Gouveia, M., Froemke, R. C., Chao, M. V., Young, W. S., et al. (2016) · Neuron · doi:10.1016/j.neuron.2016.03.033 · Cited by 359 · see citing works
Widom, C. S., & Brzustowicz, L. M. (2006) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.03.039 · Cited by 349 · see citing works
Intranasal oxytocin treatment for social deficits and biomarkers of response in children with autism
Parker, K. J., Oztan, O., Libove, R. A., Sumiyoshi, R. D., Jackson, L. P., Karhson, D. S., Summers, J. E., Hinman, K. E., Motonaga, K. S., Phillips, J. M., et al. (2017) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1705521114 · Cited by 349 · see citing works
Wotjak, C. T., Ganster, J., Kohl, G., Holsboer, F., Landgraf, R., & Engelmann, M. (1998) · Neuroscience · doi:10.1016/s0306-4522(97)00683-0 · Cited by 345 · see citing works
Yatawara, C. J., Einfeld, S. L., Hickie, I. B., Davenport, T. A., & Guastella, A. J. (2016) · Molecular Psychiatry · doi:10.1038/mp.2015.162 · Cited by 344 · see citing works
Landgraf, R., Gerstberger, R., Montkowski, A., Probst, J., Wotjak, C., Holsboer, F., & Engelmann, M. (1995) · The Journal of Neuroscience · doi:10.1523/jneurosci.15-06-04250.1995 · Cited by 341 · see citing works
Central vasopressin and oxytocin release: regulation of complex social behaviours
VEENEMA, A., & NEUMANN, I. (2008) · Progress in Brain Research · doi:10.1016/s0079-6123(08)00422-6 · Cited by 338 · see citing works
Grippo, A. J., Gerena, D., Huang, J., Kumar, N., Shah, M., Ughreja, R., & Sue Carter, C. (2007) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2007.07.004 · Cited by 336 · see citing works
Oxytocin-dependent reopening of a social reward learning critical period with MDMA
Nardou, R., Lewis, E. M., Rothhaas, R., Xu, R., Yang, A., Boyden, E., & Dölen, G. (2019) · Nature · doi:10.1038/s41586-019-1075-9 · Cited by 334 · see citing works
Reduced spontaneous but relatively normal deliberate vicarious representations in psychopathy
Meffert, H., Gazzola, V., den Boer, J. A., Bartels, A. A. J., & Keysers, C. (2013) · Brain · doi:10.1093/brain/awt190 · Cited by 318 · see citing works
Self-citationSex-specific influences of vasopressin on human social communication
Thompson, R. R., George, K., Walton, J. C., Orr, S. P., & Benson, J. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0600406103 · Cited by 312 · see citing works
Lukkes, J. L., Mokin, M. V., Scholl, J. L., & Forster, G. L. (2008) · Hormones and Behavior · doi:10.1016/j.yhbeh.2008.10.014 · Cited by 307 · see citing works
Pedersen, C. A., Gibson, C. M., Rau, S. W., Salimi, K., Smedley, K. L., Casey, R. L., Leserman, J., Jarskog, L. F., & Penn, D. L. (2011) · Schizophrenia Research · doi:10.1016/j.schres.2011.07.027 · Cited by 305 · see citing works
Bandelow, B., Krause, J., Wedekind, D., Broocks, A., Hajak, G., & Rüther, E. (2005) · Psychiatry Research · doi:10.1016/j.psychres.2003.07.008 · Cited by 299 · see citing works
Olazábal, D. E., & Young, L. J. (2006) · Neuroscience · doi:10.1016/j.neuroscience.2006.04.017 · Cited by 289 · see citing works
Albers, H. E. (2012) · Hormones and Behavior · doi:10.1016/j.yhbeh.2011.10.007 · Cited by 288 · see citing works
A circuit from hippocampal CA2 to lateral septum disinhibits social aggression
Leroy, F., Park, J. M., Asok, A., Brann, D. H., Meira, T., Boyle, L. M., Buss, E. W., Kandel, E. R., & Siegelbaum, S. A. (2018) · Nature · doi:10.1038/s41586-018-0772-0 · Cited by 277 · see citing works
Immunohistochemical localization of oxytocin receptors in human brain
Boccia, M. L., Petrusz, P., Suzuki, K., Marson, L., & Pedersen, C. A. (2013) · Neuroscience · doi:10.1016/j.neuroscience.2013.08.048 · Cited by 276 · see citing works
Effects of early life stress on adult male aggression and hypothalamic vasopressin and serotonin.
Veenema, A. H., Blume, A., Niederle, D., Buwalda, B., & Neumann, I. D. (2006) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2006.05045.x · Cited by 271 · see citing works
Veenema, A. H. (2009) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2009.03.003 · Cited by 268 · see citing works
Veenema, A. H., Bredewold, R., & Neumann, I. D. (2007) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2007.02.008 · Cited by 263 · see citing works
Blanchard, J. L., Horan, W. P., & Brown, S. A. (2001) · Journal of Abnormal Psychology · doi:10.1037/0021-843x.110.3.363 · Cited by 262 · see citing works
Post-learning intranasal oxytocin modulates human memory for facial identity
Savaskan, E., Ehrhardt, R., Schulz, A., Walter, M., & Schächinger, H. (2008) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2007.12.004 · Cited by 262 · see citing works
Vasopressin receptor blockade in the anterior hypothalamus suppresses aggression in hamsters
Ferris, C. F., & Potegal, M. (1988) · Physiology & Behavior · doi:10.1016/0031-9384(88)90144-8 · Cited by 259 · see citing works
Influence of environmental exposure on human epigenetic regulation
Marsit, C. J. (2015) · Journal of Experimental Biology · doi:10.1242/jeb.106971 · Cited by 252 · see citing works
Ahern, T. H. (2009) · Frontiers in Behavioral Neuroscience · doi:10.3389/neuro.08.017.2009 · Cited by 239 · see citing works
Effects of oxytocin on recollections of maternal care and closeness
Bartz, J. A., Zaki, J., Ochsner, K. N., Bolger, N., Kolevzon, A., Ludwig, N., & Lydon, J. E. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1012669107 · Cited by 235 · see citing works
Baribeau, D. A., & Anagnostou, E. A. (2015) · Frontiers in Neuroscience · doi:10.3389/fnins.2015.00335 · Cited by 229 · see citing works
Engelmann, M., & Landgraf, R. (1994) · Physiology & Behavior · doi:10.1016/0031-9384(94)90022-1 · Cited by 225 · see citing works
Interplay of oxytocin, vasopressin, and sex hormones in the regulation of social recognition
Gabor, C. S., Phan, A., Clipperton-Allen, A. E., Kavaliers, M., & Choleris, E. (2012) · Behavioral Neuroscience · doi:10.1037/a0026464 · Cited by 221 · see citing works
Testosterone facilitates aggression by modulating vasopressin receptors in the hypothalamus
Delville, Y., Mansour, K. M., & Ferris, C. F. (1996) · Physiology & Behavior · doi:10.1016/0031-9384(95)02246-5 · Cited by 218 · see citing works
Oxytocin makes people trusting, not gullible
Mikolajczak, M., Gross, J. J., Lane, A., Corneille, O., de Timary, P., & Luminet, O. (2010) · Psychological Science · doi:10.1177/0956797610377343 · Cited by 216 · see citing works
Low doses of oxytocin facilitate social recognition in rats
Popik, P., Vetulani, J., & van Ree, J. M. (1992) · Psychopharmacology · doi:10.1007/bf02253591 · Cited by 212 · see citing works
Goldman, M. B., Marlow-O’Connor, M., Torres, I. J., & Carter, C. S. (2007) · Schizophrenia Research · doi:10.1016/j.schres.2007.09.019 · Cited by 211 · see citing works
Lukas, M., Toth, I., Veenema, A. H., & Neumann, I. D. (2013) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2012.09.018 · Cited by 211 · see citing works
Sensitivity to Intranasal Oxytocin in Adult Men with Early Parental Separation
Meinlschmidt, G., & Heim, C. C. (2006) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.09.007 · Cited by 210 · see citing works
Skuse, D. H., Lori, A., Cubells, J. F., Lee, I., Conneely, K. N., Puura, K., Lehtimäki, T., Binder, E. B., & Young, L. J. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1302985111 · Cited by 207 · see citing works
Abnormal corticosterone regulation in an immature rat model of continuous chronic stress
Gilles, E. E., Schultz, L., & Baram, T. Z. (1996) · Pediatric Neurology · doi:10.1016/0887-8994(96)00153-1 · Cited by 199 · see citing works
Freeman, S. M., & Young, L. J. (2016) · Journal of Neuroendocrinology · doi:10.1111/jne.12382 · Cited by 196 · see citing works
Early-Life Stress Induces Long-term Morphologic Changes in Primate Brain
Spinelli, S., Chefer, S. I., Suomi, S. J., Higley, J. D., Barr, C. S., & Stein, E. A. (2009) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2009.52 · Cited by 193 · see citing works
Bianchi, M., Fone, K. C. F., Azmi, N., Heidbreder, C. A., Hagan, J. J., & Marsden, C. A. (2006) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2006.05170.x · Cited by 191 · see citing works
Veenema, A. H., & Neumann, I. D. (2009) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2008.10.017 · Cited by 191 · see citing works
The effects of vasopressin on human facial responses related to social communication
Thompson, R. R., Gupta, S., Miller, K., Mills, S. D., & Orr, S. P. (2003) · Psychoneuroendocrinology · doi:10.1016/s0306-4530(02)00133-6 · Cited by 184 · see citing works
Choleris, E., Little, S. R., Mong, J. A., Puram, S. V., Langer, R., & Pfaff, D. W. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0700670104 · Cited by 183 · see citing works
Lukas, M., Bredewold, R., Neumann, I. D., & Veenema, A. H. (2010) · Neuropharmacology · doi:10.1016/j.neuropharm.2009.06.020 · Cited by 183 · see citing works
Unternaehrer, E., Meyer, A. H., Burkhardt, S. C. A., Dempster, E., Staehli, S., Theill, N., Lieb, R., & Meinlschmidt, G. (2015) · Stress · doi:10.3109/10253890.2015.1038992 · Cited by 181 · see citing works
Veenema, A. H., Beiderbeck, D. I., Lukas, M., & Neumann, I. D. (2010) · Hormones and Behavior · doi:10.1016/j.yhbeh.2010.03.006 · Cited by 180 · see citing works
Developmental Perspectives on Oxytocin and Vasopressin
Hammock, E. A. D. (2014) · Neuropsychopharmacology · doi:10.1038/npp.2014.120 · Cited by 177 · see citing works
Reports of the childhood home environment in early-onset dysthymia and episodic major depression.
Lizardi, H., Klein, D. N., Ouimette, P. C., Riso, L. P., Anderson, R. L., & Donaldson, S. K. (1995) · Journal of Abnormal Psychology · doi:10.1037//0021-843x.104.1.132 · Cited by 174 · see citing works
Smearman, E. L., Almli, L. M., Conneely, K. N., Brody, G. H., Sales, J. M., Bradley, B., Ressler, K. J., & Smith, A. K. (2016) · Child Development · doi:10.1111/cdev.12493 · Cited by 173 · see citing works
Vasopressin and serotonin interactions in the control of agonistic behavior
Ferris, C. F., & Delville, Y. (1994) · Psychoneuroendocrinology · doi:10.1016/0306-4530(94)90043-4 · Cited by 172 · see citing works
Cerebrospinal fluid oxytocin, life history of aggression, and personality disorder
Lee, R., Ferris, C. F., de Kar, L. D. V., & Coccaro, E. F. (2009) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2009.06.002 · Cited by 172 · see citing works
Simeon, D., Bartz, J. A., Hamilton, H., Crystal, S., Braun, A. R., Ketay, S., & Hollander, E. (2011) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2011.03.013 · Cited by 167 · see citing works
Landgraf, R., Frank, E., Aldag, J. M., Neumann, I. D., Sharer, C. A., Ren, X., Terwilliger, E. F., Niwa, M., Wigger, A., & Young, L. J. (2003) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.2003.02750.x · Cited by 164 · see citing works
Bester‐Meredith, J. K., & Marler, C. A. (2001) · Hormones and Behavior · doi:10.1006/hbeh.2001.1666 · Cited by 163 · see citing works
Veenema, A. H. (2011) · Hormones and Behavior · doi:10.1016/j.yhbeh.2011.12.002 · Cited by 157 · see citing works
Freeman, S. M., Walum, H., Inoue, K., Smith, A. L., Goodman, M. M., Bales, K. L., & Young, L. J. (2014) · Neuroscience · doi:10.1016/j.neuroscience.2014.04.055 · Cited by 153 · see citing works
Everts, H. G. J., & Koolhaas, J. M. (1999) · Behavioural Brain Research · doi:10.1016/s0166-4328(98)00004-7 · Cited by 148 · see citing works
Emotion recognition and oxytocin in patients with schizophrenia
Averbeck, B. B., Bobin, T., Evans, S., & Shergill, S. S. (2011) · Psychological Medicine · doi:10.1017/s0033291711001413 · Cited by 144 · see citing works
Developmental experiences and the oxytocin receptor system
Bales, K. L., & Perkeybile, A. M. (2012) · Hormones and Behavior · doi:10.1016/j.yhbeh.2011.12.013 · Cited by 142 · see citing works
Beiderbeck, D. I., Neumann, I. D., & Veenema, A. H. (2007) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2007.05974.x · Cited by 142 · see citing works
Kelly, A. M., & Goodson, J. L. (2014) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2014.04.005 · Cited by 141 · see citing works
Neurobiology of aggression and violence in schizophrenia.
Soyka, M. (2011) · Schizophrenia bulletin · doi:10.1093/schbul/sbr103 · Cited by 139 · see citing works
Reports of the childhood home environment in early-onset dysthymia and episodic major depression.
Lizardi, H., Klein, D. N., Ouimette, P. C., et al. (1995) · Journal of Abnormal Psychology · doi:10.1037/0021-843x.104.1.132 · Cited by 136 · see citing works
Giovenardi, M., Padoin, M. J., Cadore, L. P., & Lucion, A. B. (1998) · Physiology & Behavior · doi:10.1016/s0031-9384(97)00434-4 · Cited by 135 · see citing works
Medial amygdala and aggressive behavior: Interaction between testosterone and vasopressin
Koolhaas, J. M., Brink, T. H. C. V. D., Roozendaal, B., & Boorsma, F. (1990) · Aggressive Behavior · doi:10.1002/1098-2337(1990)16:3/4 · Cited by 134 · see citing works
Bosch, O. J., Pförtsch, J., Beiderbeck, D. I., Landgraf, R., & Neumann, I. D. (2010) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.2010.01984.x · Cited by 130 · see citing works
Mikolajczak, M., Pinon, N., Lane, A., de Timary, P., & Luminet, O. (2010) · Biological Psychology · doi:10.1016/j.biopsycho.2010.05.010 · Cited by 129 · see citing works
Bosch, O. J., Krömer, S. A., Brunton, P. J., & Neumann, I. D. (2004) · Neuroscience · doi:10.1016/j.neuroscience.2003.11.028 · Cited by 129 · see citing works
Veenema, A. H., Bredewold, R., & De Vries, G. J. (2012) · Hormones and Behavior · doi:10.1016/j.yhbeh.2011.10.002 · Cited by 129 · see citing works
Vasopressin, oxytocin and neurophysins in the human brain and spinal cord
Jenkins, J. S., Ang, V. T. Y., Hawthorn, J., Rossor, M. N., & Iversen, L. L. (1984) · Brain Research · doi:10.1016/0006-8993(84)90656-5 · Cited by 126 · see citing works
Oxytocin mediates entrainment of sensory stimuli to social cues of opposing valence
Choe, H. K., Reed, M. D., Benavidez, N., Montgomery, D., Soares, N., Yim, Y. S., & Choi, G. B. (2015) · Neuron · doi:10.1016/j.neuron.2015.06.022 · Cited by 124 · see citing works
Lukas, M., Bredewold, R., Landgraf, R., Neumann, I. D., & Veenema, A. H. (2011) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2010.11.007 · Cited by 122 · see citing works
Reppert, S. M., & Uhl, G. R. (1987) · Endocrinology · doi:10.1210/endo-120-6-2483 · Cited by 118 · see citing works
(1981) · PubMed · Cited by 117 · see citing works
Sex-dependent regulation of social reward by oxytocin: an inverted U hypothesis
Borland, J. M., Rilling, J. K., Frantz, K. J., & Albers, H. E. (2019) · Neuropsychopharmacology · doi:10.1038/s41386-018-0129-2 · Cited by 116 · see citing works
Barrett, C. E., Arambula, S. E., & Young, L. J. (2015) · Translational Psychiatry · doi:10.1038/tp.2015.73 · Cited by 115 · see citing works
Popik, P., & van Ree, J. M. (1991) · European Neuropsychopharmacology · doi:10.1016/0924-977x(91)90010-r · Cited by 114 · see citing works
Plasma oxytocin levels in female fibromyalgia syndrome patients
Anderberg, U. M., & Uvnäs‐Moberg, K. (2000) · Zeitschrift für Rheumatologie · doi:10.1007/s003930070045 · Cited by 111 · see citing works
Orally active vasopressin V1a receptor antagonist, SRX251, selectively blocks aggressive behavior
Ferris, C. F., Lu, S., Messenger, T. L., Guillon, C. D., Heindel, N. D., Miller, M., KOPPEL, G. A., Bruns, F., & Simon, N. G. (2006) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2006.01.001 · Cited by 111 · see citing works
Oxytocin Inhibits Aggression in Female Syrian Hamsters
Harmon, A. C., Huhman, K. L., Moore, T. O., & Albers, H. E. (2002) · Journal of Neuroendocrinology · doi:10.1046/j.1365-2826.2002.00863.x · Cited by 108 · see citing works
Wang, X., Labermaier, C., Holsboer, F., Wurst, W., Deussing, J. M., Müller, M. B., & Schmidt, M. V. (2012) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2012.08148.x · Cited by 108 · see citing works
Induction of FOS Immunoreactivity in Oxytocin Neurons after Sexual Activity in Female Rats
Flanagan‐Cato, L. M., Pfaus, J. G., Pfaff, D. W., & McEwen, B. S. (2008) · Neuroendocrinology · doi:10.1159/000126562 · Cited by 103 · see citing works
Altstein, M., & Gainer, H. (1988) · Journal of Neuroscience · doi:10.1523/jneurosci.08-11-03967.1988 · Cited by 102 · see citing works
Overview of cellular electrophysiological actions of vasopressin
Raggenbass, M. (2008) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2007.11.074 · Cited by 102 · see citing works
Gouin, J.-P., Zhou, Q. Q., Booij, L., Boivin, M., Côté, S. M., Hébert, M., Ouellet‐Morin, I., Moshe Szyf, A., Tremblay, R. E., Turecki, G., et al. (2017) · Scientific Reports · doi:10.1038/s41598-017-07950-x · Cited by 102 · see citing works
Sabihi, S., Dong, S. M., Durosko, N. E., & Leuner, B. (2014) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2014.00258 · Cited by 101 · see citing works
Rincón‐Cortés, M., & Sullivan, R. M. (2016) · Translational Psychiatry · doi:10.1038/tp.2016.205 · Cited by 101 · see citing works
Murakami, G., Hunter, R. G., Fontaine, C., Ribeiro, A., & Pfaff, D. (2011) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2011.07761.x · Cited by 99 · see citing works
Lateral septal vasopressin in rats: role in social and object recognition?
Everts, H. G. J., & Koolhaas, J. M. (1997) · Brain Research · doi:10.1016/s0006-8993(97)00269-2 · Cited by 98 · see citing works
Desbonnet, L., Garrett, L., Daly, E., McDermott, K. W. G., & Dinan, T. G. (2008) · International Journal of Developmental Neuroscience · doi:10.1016/j.ijdevneu.2008.02.004 · Cited by 97 · see citing works
Effect of photoperiod on vasopressin-induced aggression in Syrian hamsters
Caldwell, H. K., & Albers, H. E. (2004) · Hormones and Behavior · doi:10.1016/j.yhbeh.2004.04.006 · Cited by 97 · see citing works
AVP V selective antagonist SSR149415 blocks aggressive behaviors in hamsters
Blanchard, R. J., Griebel, G., Farrokhi, C. B., Markham, C. M., YANG, M., & Blanchard, D. C. (2004) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2004.10.024 · Cited by 94 · see citing works
Pincus, D. (2010) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2010.00134 · Cited by 91 · see citing works
Leng, G., Pineda, R., Sabatier, N., & Ludwig, M. (2015) · Journal of Endocrinology · doi:10.1530/joe-15-0087 · Cited by 85 · see citing works
Sex differences in the regulation of offensive aggression and dominance by arginine-vasopressin
Terranova, J. I., Ferris, C. F., & Albers, H. E. (2017) · Frontiers in Endocrinology · doi:10.3389/fendo.2017.00308 · Cited by 85 · see citing works
Cao, Y., Wu, R., Tai, F., Zhang, X., Yu, P., An, X., Qiao, X., & Hao, P. (2013) · Hormones and Behavior · doi:10.1016/j.yhbeh.2013.11.005 · Cited by 82 · see citing works
Hernández, V. S., Hernández, O. R., de la Mora, M. P., Gómora, M. J., Fuxé, K., Eiden, L. E., & Zhang, L. (2016) · Frontiers in Neural Circuits · doi:10.3389/fncir.2016.00092 · Cited by 80 · see citing works
Thibonnier, M., Graves, M. K., Wagner, M., Auzan, C., Clauser, É., & Willard, H. F. (1996) · Genomics · doi:10.1006/geno.1996.0055 · Cited by 80 · see citing works
A neural network underlying individual differences in emotion and aggression in male golden hamsters
David, J. T., Cervantes, M., Trosky, K. A., Salinas, J. A., & Delville, Y. (2004) · Neuroscience · doi:10.1016/j.neuroscience.2004.04.031 · Cited by 79 · see citing works
Aleyasin, H., Flanigan, M. E., & Russo, S. J. (2018) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2018.02.013 · Cited by 79 · see citing works
Role of V1a vasopressin receptors in the control of aggression in Syrian hamsters
Elliott Albers, H., Dean, A., Karom, M. C., Smith, D., & Huhman, K. L. (2006) · Brain Research · doi:10.1016/j.brainres.2005.12.081 · Cited by 78 · see citing works
Kohl, C., Wang, X.-D., Grosse, J., Fournier, C., Harbich, D., Westerholz, S., Li, J.-T., Bacq, A., Sippel, C., Hausch, F., et al. (2015) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2015.02.016 · Cited by 76 · see citing works
Early rearing history influences oxytocin receptor epigenetic regulation in rhesus macaques
Baker, M., Lindell, S. G., Driscoll, C. A., Zhou, Z., Yuan, Q., Schwandt, M. L., Miller-Crews, I., Simpson, E. A., Paukner, A., Ferrari, P. F., et al. (2017) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1706206114 · Cited by 74 · see citing works
Oxytocin and vasopressin: Social neuropeptides with complex neuromodulatory functions
Benarroch, E. E. (2013) · Neurology · doi:10.1212/wnl.0b013e31828cfb15 · Cited by 74 · see citing works
Ontogeny of hypothalamic vasopressin, oxytocin and somatostatin gene expression
Almazán, G., Lefebvre, D. L., & Zingg, H. H. (1989) · Developmental Brain Research · doi:10.1016/0165-3806(89)90008-4 · Cited by 72 · see citing works
Dumais, K. M., Alonso, A. G., Immormino, M. A., Bredewold, R., & Veenema, A. H. (2015) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2015.11.007 · Cited by 72 · see citing works
Oxytocin reduces neural activity in the pain circuitry when seeing pain in others
Bos, P. A., Montoya, E. R., Hermans, E. J., Keysers, C., & van Honk, J. (2015) · NeuroImage · doi:10.1016/j.neuroimage.2015.03.049 · Cited by 72 · see citing works
Self-citationEarly life stress disrupts peripubertal development of aggression in male mice
Tsuda, M. C., Yamaguchi, N., & Ogawa, S. (2011) · NeuroReport · doi:10.1097/wnr.0b013e328344495a · Cited by 72 · see citing works
Altered oxytocin and vasopressin levels in autistic children in Central Saudi Arabia
AL-Ayadhi, L. Y. (2005) · Neurosciences · doi:10.17712/1658-3183.1311 · Cited by 71 · see citing works
Vasopressin Localization and Putative Functions in the Brain
Buijs, R. M. (1987) · Springer eBooks · doi:10.1007/978-1-4615-8129-1_2 · Cited by 70 · see citing works
Laurent-Huck, F. M., Hindelang, C., Klein, M. J., Stoeckel, M. E., & Félix, J. M. (1989) · Developmental Brain Research · doi:10.1016/0165-3806(89)90152-1 · Cited by 69 · see citing works
Managing irritability and aggression in autism spectrum disorders in children and adolescents
Robb, A. S. (2010) · Developmental Disabilities Research Reviews · doi:10.1002/ddrr.118 · Cited by 68 · see citing works
Tabbaa, M., Lei, K., Liu, Y., & Wang, Z. (2016) · Neuroscience · doi:10.1016/j.neuroscience.2016.12.011 · Cited by 68 · see citing works
Activation of Supraoptic Oxytocin Neurons by Secretin Facilitates Social Recognition
Takayanagi, Y., Yoshida, M., Takashima, A., Takanami, K., Yoshida, S., Nishimori, K., Nishijima, I., Sakamoto, H., Yamagata, T., & Onaka, T. (2015) · Biological Psychiatry · doi:10.1016/j.biopsych.2015.11.021 · Cited by 66 · see citing works
Rigney, N., Whylings, J., Mieda, M., de Vries, G. J., & Petrulis, A. (2019) · eNeuro · doi:10.1523/eneuro.0415-18.2019 · Cited by 63 · see citing works
Murgatroyd, C., Peña, C. J., Podda, G., Nestler, E. J., & Nephew, B. C. (2015) · Neuropeptides · doi:10.1016/j.npep.2015.05.002 · Cited by 61 · see citing works
Hypothalamic vasopressin system regulation by maternal separation: Its impact on anxiety in rats
Zhang, L., Hernández, V. S., Liu, B., Medina‐Pizarro, M., Nava-Kopp, A. T., Irles, C., & Morales, M. A. (2012) · Neuroscience · doi:10.1016/j.neuroscience.2012.03.046 · Cited by 60 · see citing works
Clipperton‐Allen, A. E., Lee, A. W., Reyes, A., Devidze, N., Phan, A., Pfaff, D. W., & Choleris, E. (2011) · Physiology & Behavior · doi:10.1016/j.physbeh.2011.10.025 · Cited by 58 · see citing works
Neurohypophyseal peptides in the developing rat fetus
Sinding, C., ROBINSON, A. G., SEIF, S. M., & Schmid, P. G. (1980) · Brain Research · doi:10.1016/0006-8993(80)90875-6 · Cited by 58 · see citing works
Duque‐Wilckens, N., Steinman, M. Q., Laredo, S. A., Hao, R., Perkeybile, A. M., Bales, K. L., & Trainor, B. C. (2016) · Neuropharmacology · doi:10.1016/j.neuropharm.2016.07.018 · Cited by 52 · see citing works
Ophir, A. G., Zheng, D.-J., Eans, S. O., & Phelps, S. M. (2009) · Behavioral Neuroscience · doi:10.1037/a0016663 · Cited by 45 · see citing works
Early life stress-induced alterations in rat brain structures measured with high resolution MRI
Sarabdjitsingh, R. A., Loi, M., Joëls, M., Dijkhuizen, R. M., & van der Toorn, A. (2017) · PLoS ONE · doi:10.1371/journal.pone.0185061 · Cited by 41 · see citing works
The hypothalamic magnocellular neurosecretory system in developing rats
Lipari, E. F., Lipari, D., Gerbino, A., Liberto, D. D., Bellafiore, M., Catalano, M., & Valentino, B. (2009) · European Journal of Histochemistry · doi:10.4081/1626 · Cited by 40 · see citing works
Bosch, O. J., Sartori, S. B., Singewald, N., & Neumann, I. D. (2007) · Stress · doi:10.1080/10253890701223197 · Cited by 34 · see citing works
Effects of nucleus accumbens oxytocin and its antagonist on social approach behavior
Yu, C. J., Zhang, S. W., & Tai, F. (2016) · Behavioural Pharmacology · doi:10.1097/fbp.0000000000000212 · Cited by 33 · see citing works
Wei, B., Tai, F., Liu, X., Ma, L., Yang, X., Jia, R., & Zhang, X. (2013) · Physiology & Behavior · doi:10.1016/j.physbeh.2013.02.005 · Cited by 33 · see citing works
Yu, P., Zhang, H., Li, X., He, F., & Tai, F. (2015) · Hormones and Behavior · doi:10.1016/j.yhbeh.2015.05.006 · Cited by 25 · see citing works
Fujiwara, T., Sanada, M., Kofuji, T., & Akagawa, K. (2016) · Journal of Neurochemistry · doi:10.1111/jnc.13634 · Cited by 25 · see citing works
Bloch, B., Guitteny, A. F., Chouham, S., Mougin, C., Roget, A., & T�oule, R. (1990) · Cellular and Molecular Neurobiology · doi:10.1007/bf00733638 · Cited by 20 · see citing works
The role of m6A-RNA methylation in stress response regulationPreprint
Engel, M., Röh, S., Eggert, C., Kaplick, P. M., Tietze, L., Arloth, J., Weber, P., Rex-Haffner, M., Jakovcevski, M., Uhr, M., et al. (2017) · bioRxiv · doi:10.1101/200402 · Cited by 20 · see citing works
Wang, L., Zhang, W., Wu, R., Kong, L., Feng, W., Cao, Y., Tai, F., & Zhang, X. (2014) · Developmental Psychobiology · doi:10.1002/dev.21202 · Cited by 19 · see citing works
Social interaction test: a sensitive method for examining autism-related behavioral deficits
Ikeda, K., Sato, A., Mizuguchi, M., & Ikeda, K. (2013) · Protocol Exchange · doi:10.1038/protex.2013.046 · Cited by 18 · see citing works
Quantitative changes in neurohypophyseal peptides in the developing brain
Sinding, C., Czernichow, P., SEIF, S. M., & ROBINSON, A. G. (1980) · Peptides · doi:10.1016/0196-9781(80)90102-3 · Cited by 17 · see citing works
Alcántara‐Alonso, V., Amaya, M. I., Matamoros‐Trejo, G., & de Gortari, P. (2017) · Neuropeptides · doi:10.1016/j.npep.2017.01.006 · Cited by 16 · see citing works
Social Recognition Task in the Rat
Lemaire, M. (2003) · Current Protocols in Pharmacology · doi:10.1002/0471141755.ph0530s20 · Cited by 15 · see citing works
SOCIAL BIOLOGY OF RODENTS: TRENDS, CHALLENGES, AND FUTURE DIRECTIONS
Lacey, E. A., & Solomon, N. G. (2003) · Journal of Mammalogy · doi:10.1644/ble-016 · Cited by 11 · see citing works
Wolf, G., Kiessig, R., & Landgraf, R. (2009) · Experimental and Clinical Endocrinology & Diabetes · doi:10.1055/s-0029-1210337 · Cited by 11 · see citing works
Methods in behavioral pharmacology: measurement of aggression
Kemble, E. D., Blanchard, D. C., & Blanchard, R. J. (1993) · Techniques in the behavioral and neural sciences · doi:10.1016/b978-0-444-81444-9.50026-2 · Cited by 6 · see citing works
Heuser, I., Bissette, G., Dettling, M., Schweiger, U., Gotthardt, U., Schmider, J., Lammers, C.-H., Nemeroff, C. B., & Holsboer, F. (1998) · Depression and Anxiety · doi:10.1002/(sici)1520-6394(1998)8:2
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Ellis, B. J., Horn, A. J., Carter, C. S., van IJzendoorn, M. H., & Bakermans‐Kranenburg, M. J. (2021) · Clinical Psychology Review · doi:10.1016/j.cpr.2021.101985 · Cited by 103 · see citing works
Coordination of social behaviors by the bed nucleus of the stria terminalis
Flanigan, M. E., & Kash, T. L. (2022) · European Journal of Neuroscience · doi:10.1111/ejn.14991 · Cited by 71 · see citing works
Sex, love and oxytocin: Two metaphors and a molecule
Carter, C. S. (2022) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2022.104948 · Cited by 70 · see citing works
The oxytocin system and early‐life experience‐dependent plastic changes
Onaka, T., & Takayanagi, Y. (2021) · Journal of Neuroendocrinology · doi:10.1111/jne.13049 · Cited by 60 · see citing works
Oxytocin and love: myths, metaphors and mysteries.
Carter, C. S. (2022) · Comprehensive Psychoneuroendocrinology · doi:10.1016/j.cpnec.2021.100107 · Cited by 57 · see citing works
Hormones and neuroplasticity: A lifetime of adaptive responses
Been, L. E., Sheppard, P. A. S., Galea, L. A. M., & Glasper, E. R. (2021) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2021.11.029 · Cited by 58 · see citing works
Birth signalling hormones and the developmental consequences of caesarean delivery
Kenkel, W. M. (2020) · Journal of Neuroendocrinology · doi:10.1111/jne.12912 · Cited by 45 · see citing works
Early life stress and brain plasticity: from molecular alterations to aberrant memory and behavior
Lopatina, O. L., Panina, Y. A., Malinovskaya, N. A., & Salmina, A. B. (2020) · Reviews in the Neurosciences · doi:10.1515/revneuro-2020-0077 · Cited by 44 · see citing works
Morel, C., Sánchez, I. M., Cherifi, Y., Chartrel, N., & Heijtz, R. D. (2023) · Neuropharmacology · doi:10.1016/j.neuropharm.2023.109479 · Cited by 42 · see citing works
Sensitive phases in the development of rodent social behavior
Sachser, N., Zimmermann, T. D., Hennessy, M. B., & Kaiser, S. (2020) · Current Opinion in Behavioral Sciences · doi:10.1016/j.cobeha.2020.07.014 · Cited by 40 · see citing works
Marvar, P. J., Andero, R., Hurlemann, R., Lago, T. R., Zelikowsky, M., & Dabrowska, J. (2021) · Journal of Neuroscience · doi:10.1523/jneurosci.1647-20.2020 · Cited by 29 · see citing works
Goncharova, N. D. (2020) · BioEssays · doi:10.1002/bies.202000007 · Cited by 31 · see citing works
Nold, V., Richter, N., Hengerer, B., Kolassa, I., & Allers, K. A. (2020) · European Journal of Neuroscience · doi:10.1111/ejn.14999 · Cited by 26 · see citing works
The evolved nest, oxytocin functioning, and prosocial development
Tarsha, M. S., & Narvaez, D. (2023) · Frontiers in Psychology · doi:10.3389/fpsyg.2023.1113944 · Cited by 25 · see citing works
Love and longevity: A Social Dependency Hypothesis
Horn, A. J., & Carter, C. S. (2021) · Comprehensive Psychoneuroendocrinology · doi:10.1016/j.cpnec.2021.100088 · Cited by 22 · see citing works
Emmons, R., Sadok, T., Rovero, N. G., Belnap, M. A., Henderson, H. J. M., Quan, A., Toro, N. J. D., & Halladay, L. R. (2020) · Journal of Neuroscience Research · doi:10.1002/jnr.24644 · Cited by 19 · see citing works
Jacob, S., Anagnostou, E. A., Hollander, E., Jou, R. J., McNamara, N., Sikich, L., Tobe, R. H., Murphy, D., McCracken, J. T., Ashford, E., et al. (2022) · Molecular Autism · doi:10.1186/s13229-022-00505-6 · Cited by 20 · see citing works
Sailer, L. L., Patel, P. P., Park, A. H., Moon, J., Hanadari-Levy, A., & Ophir, A. G. (2022) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2022.931549 · Cited by 17 · see citing works
Joushi, S., Taherizadeh, Z., Esmaeilpour, K., & Sheibani, V. (2021) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2021.173318 · Cited by 18 · see citing works
Gimsa, U., Brückmann, R., Tuchscherer, A., Tuchscherer, M., & Kanitz, E. (2022) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2022.980350 · Cited by 17 · see citing works
Extrahippocampal Contributions to Social Memory: The Role of Septal Nuclei
Shivakumar, A. B., Mehak, S. F., Jijimon, F., & Gangadharan, G. (2024) · Biological Psychiatry · doi:10.1016/j.biopsych.2024.04.018 · Cited by 17 · see citing works
Alone, in the dark: The extraordinary neuroethology of the solitary blind mole rat
Kashash, Y., Smarsh, G. C., Zilkha, N., Yovel, Y., & Kimchi, T. (2022) · eLife · doi:10.7554/elife.78295 · Cited by 15 · see citing works
Sex differences of oxytocin and vasopressin in social behaviors
Lu, Q., & Hu, S. (2021) · Handbook of clinical neurology · doi:10.1016/b978-0-12-820107-7.00005-7 · Cited by 17 · see citing works
Kashkouli, M., Sadatmahalleh, S. J., Ziaei, S., Kazemnejad, A., Saber, A., Darvishnia, H., & Azarbayjani, K. (2023) · Scientific Reports · doi:10.1038/s41598-022-27223-6 · Cited by 13 · see citing works
Boyle, C. A., Hu, B., Quaintance, K. L., & Lei, S. (2021) · The Journal of Physiology · doi:10.1113/jp281260 · Cited by 13 · see citing works
Müller, S., Sicorello, M., Moser, D., Frach, L., Limberg, A., Gumpp, A. M., Ramo‐Fernández, L., Köhler‐Dauner, F., Fegert, J. M., Waller, C., et al. (2023) · Translational Psychiatry · doi:10.1038/s41398-023-02548-6 · Cited by 12 · see citing works
Ohta, K., Araki, C., Ujihara, H., Iseki, K., Suzuki, S., Otabi, H., Kumei, H., Warita, K., Kusaka, T., & Miki, T. (2023) · Journal of Neurochemistry · doi:10.1111/jnc.16020 · Cited by 12 · see citing works
Ceschim, V. C., Sumarán, P., Borges, A. A., Girardi, C. E. N., & Suchecki, D. (2021) · Hormones and Behavior · doi:10.1016/j.yhbeh.2021.104928 · Cited by 12 · see citing works
Corredor, K., Duran, J. M., Herrera-Isaza, L., Forero, S., Quintanilla, J. P., Gomez, A., Martínez, G. S., & Cárdenas, F. P. (2022) · Frontiers in Physiology · doi:10.3389/fphys.2022.837661 · Cited by 14 · see citing works
Hu, B., Boyle, C. A., & Lei, S. (2021) · Journal of Cellular Physiology · doi:10.1002/jcp.30535 · Cited by 11 · see citing works
Early Life Trauma and Social Processing in HIV: The Role of Neuroendocrine Factors and Inflammation
Rubin, L. H., Bhattacharya, D., Fuchs, J., Matthews, A., Abdellah, S., Veenhuis, R. T., Langenecker, S. A., Weber, K. M., Nazarloo, H. P., Keating, S. M., et al. (2022) · Psychosomatic Medicine · doi:10.1097/psy.0000000000001124 · Cited by 8 · see citing works
Ortega, M. A., Montero, C. G., Fraile‐Μartinez, O., León-Oliva, D. D., Boaru, D. L., Bravo, C., León-Luis, J. A. D., Sáez, M. A., Asúnsolo, Á., Gerechter, I. R., et al. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241210254 · Cited by 8 · see citing works
Henderson, H. J. M., Etem, G., Bjorni, M., Belnap, M. A., Rosellini, B., & Halladay, L. R. (2021) · Behavioural Brain Research · doi:10.1016/j.bbr.2021.113241 · Cited by 7 · see citing works
Lei, S., Hu, B., & Rezagholizadeh, N. (2021) · Neuropharmacology · doi:10.1016/j.neuropharm.2021.108565 · Cited by 6 · see citing works
A Cross-Generational Methylomic Signature of Infant Maltreatment in Newborn Rhesus Macaques
Lardenoije, R., Smulders, M. N. C. A., Morin, E. L., Howell, B., Guzman, D., Meyer, J. S., Ressler, K. J., Sánchez, M., & Klengel, T. (2025) · Biological Psychiatry · doi:10.1016/j.biopsych.2025.02.901 · Cited by 6 · see citing works
Epigenetic Modulation of Vasopressin Expression in Health and Disease
Török, B., Fazekas, C. L., Szabó, A., & Zelena, D. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22179415 · Cited by 6 · see citing works
Lei, S., Boyle, C. A., & Mastrud, M. R. (2022) · eNeuro · doi:10.1523/eneuro.0120-22.2022 · Cited by 6 · see citing works
Olazábal, D. E., Bertoni, B., Grandi, G., Musetti, D., Rey, G., Sandberg, N. Y., Fernández, L., Laporte, G., Medici, F., & Nicolaisen‐Sobesky, E. (2023) · Developmental Psychobiology · doi:10.1002/dev.22400 · Cited by 5 · see citing works
Municchi, D., Mancini, C., Nutarelli, S., Tiberi, M., D’Addario, S. L., Chila, G., Passeri, A., Massa, G., Segni, M. D., Babicola, L., et al. (2025) · Molecular Psychiatry · doi:10.1038/s41380-025-03437-8 · Cited by 4 · see citing works
Gatto, N. M., Thordardottir, E. B., Tómasson, G., Rúnarsdóttir, H., Song, H., Jakobsdóttir, J., Aspelund, T., Valdimarsdóttir, U. A., & Hauksdóttir, A. (2022) · Brain Sciences · doi:10.3390/brainsci12111559 · Cited by 4 · see citing works
The psychedelic-peptide paradox: a hormetic hypothesis
Carter, C. S. (2025) · Comprehensive Psychoneuroendocrinology · doi:10.1016/j.cpnec.2025.100303 · Cited by 4 · see citing works
Schneider-Schmid, U., Morgado, A., Heim, C. C., Klawitter, H., Hellmeyer, L., & Entringer, S. (2025) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2025.107564 · Cited by 4 · see citing works
Lee, M., & Rilling, J. K. (2025) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2025.106457 · Cited by 3 · see citing works
Ren, L., & Tai, F. (2023) · Neuroscience Letters · doi:10.1016/j.neulet.2023.137241 · Cited by 3 · see citing works
Campbell, T. S., & Roth, T. L. (2023) · Elsevier eBooks · doi:10.1016/b978-0-12-821785-6.00013-x · Cited by 3 · see citing works
Budniok, S., Bakermans‐Kranenburg, M. J., Bosmans, G., & van IJzendoorn, M. H. (2025) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2025.106500 · Cited by 2 · see citing works
Stoehr, M. C., Martin, E. M., Babalola, J. T., Xue, J., Kern, M., Li, N. Y., Winters, M. F., Bhagwagar, S., & Smith, C. J. (2026) · Journal of Neuroendocrinology · doi:10.1111/jne.70151 · Cited by 2 · see citing works
Early life stress modulates social behavior via oxytocin and arginine vasopressin in males
Liu, C., Du, Y., Zhao, Y., Wang, X., Shi, Y., Yin, X., Li, Y., & Shi, H. (2025) · European Archives of Psychiatry and Clinical Neuroscience · doi:10.1007/s00406-025-02119-4 · Cited by 1 · see citing works
Early life adversity impairs visually evoked innate defensive behaviors via oxytocin signaling
Tan, H., Su, J., Ma, S., Chen, S., Liu, Q., Yang, X., & Wang, L. (2026) · Communications Biology · doi:10.1038/s42003-026-09738-0 · Cited by 1 · see citing works
de Sá, N. F., Assad, N., Camarini, R., & Suchecki, D. (2026) · Neurobiology of Stress · doi:10.1016/j.ynstr.2026.100800 · Cited by 1 · see citing works
Mascheroni, E., Butti, N., Mambretti, F., Cordolcini, L., Castagna, A., Maucci, V., Citterio, A., Bettinelli, A., & Montirosso, R. (2026) · Frontiers in Psychology · doi:10.3389/fpsyg.2026.1763938 · Cited by 1 · see citing works
The Effect of Birth on Neural Activation in the Rodent Brain
Hoffiz, Y. C. (2022) · Digital Archive @ GSU · doi:10.57709/17328404
Jacob, S., Anagnostou, E. A., Hollander, E., Jou, R. J., McNamara, N., Sikich, L., Tobe, R. H., Murphy, D., McCracken, J., Ashford, E., et al. (2022) · Figshare · doi:10.6084/m9.figshare.20056341
- Authors
- Kompier, N. F., Keysers, C., Gazzola, V., Lucassen, P. J., & Krugers, H. J.
- Affiliations
- Netherlands Institute for Neuroscience (NL)
- University of Amsterdam (NL)
- Corresponding author
- Kompier, Nine F.
- Krugers, Harmen J.
- Venue
- Frontiers in Behavioral Neuroscience
- Publisher
- Frontiers Media SA
- Published
- 2019-07-26
- Volume
- 13
- Pages
- 143-143
- ISSN
- 1662-5153 (ISSN-L)
- PMC
- PMC6676334
- OpenAlex
- W2962706904
- Cited by
- 53
- References
- 181
- Citations by year
- 2026: 4 · 2025: 7 · 2024: 1 · 2023: 9 · 2022: 11 · 2021: 14 · 2020: 7
- FWCI
- 1.24
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Frontiers in Behavioral Neuroscience (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- KNAW Research Portal (The Royal Netherlands Academy of Arts and Sciences) (publishedVersion, other-oa)
- KNAW research portal (Royal Academy of Art and Sciences (KNAW)) (publishedVersion, other-oa)
- Data Archiving and Networked Services (DANS) (submittedVersion, other-oa)
- UvA-DARE (University of Amsterdam) (submittedVersion, cc-by)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
- Funders
- Nederlandse Organisatie voor Wetenschappelijk Onderzoek
- Topics
- Social Sciences › Psychology › Social Psychology › Neuroendocrine regulation and behavior
- Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuropeptides and Animal Physiology
- Keywords
- childhood adversity, early life stress, vasopressin, oxytocin, social behavior, aggression, social recognition, social motivation, neuropeptides, postpartum stress, rodent models, social dysfunction, psychopathology
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