Summary of the Second Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel II)

Scott M. Grundy, David W. Bilheimer, Alan Chait, Luther T. Clark, Margo A. Denke, Richard J. Havel, William R. Hazzard, Stephen B. Hulley, Donald B. Hunninghake, Robert A. Kreisberg, Penny M. Kris‐Etherton, James M. McKenney, Michael A. Newman, Ernst J. Schaefer, Burton E. Sobel, Carolyn A. Somelofski, Milton C. Weinstein, H. Bryan Brewer, James I. Cleeman, Karen A. Donato, Nancy D. Ernst, Jeffrey M. Hoeg, Basil M. Rifkind, Jacques Rossouw, Christopher T. Sempos, Joanne M. Gallivan, Maureen N. Harris, Laurie Quint-Adler·1993·JAMA

DOI 10.1001/jama.269.23.3015

Open this paper in CoChat — free account

Abstract

THE SECOND report of the Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel II, or ATP II) presents the National Cholesterol Education Program's updated recommendations for cholesterol management. It is similar to the first in general outline, and the fundamental approach to treatment of high blood cholesterol is comparable. This report continues to identify low-density lipoproteins (LDL) as the primary target of cholesterol-lowering therapy. As in the first report, the second report emphasizes the role of the clinical approach in primary prevention of coronary heart disease (CHD). Dietary therapy remains the first line of treatment of high blood cholesterol, and drug therapy is reserved for patients who are considered to be at high risk for CHD. However, the second report contains new features that distinguish it from the first. These include the following: Increased emphasis on See also pp 3002 and 3009.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

OpenAlex · 10.1001/jama.269.23.3015

Cites

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Items 1,201–1,299 of 1,299

Cardiometabolic disease staging predicts effectiveness of weight-loss therapy to prevent type 2 diabetes: pooled results from phase III clinical trials assessing phentermine/topiramate extended release
Guo, F., & Garvey, W. T. (2017) · Diabetes Care · doi:10.2337/dc17-0088 · Cited by 37
Efficacy and Safety of Adding Omega-3 Fatty Acids in Statin-treated Patients with Residual Hypertriglyceridemia: ROMANTIC (Rosuvastatin-OMAcor iN residual hyperTrIglyCeridemia), a Randomized, Double-blind, and Placebo-controlled Trial
Kim, C. H., Han, K. A., Yu, J., Lee, S. H., Jeon, H. K., Kim, S. H., Kim, S. Y., Han, K. H., Won, K., Kim, D.-B., et al. (2018) · Clinical Therapeutics · doi:10.1016/j.clinthera.2017.11.007 · Cited by 36
Phytosterols, red yeast rice, and lifestyle changes instead of statins: a randomized, double-blinded, placebo-controlled trial
Becker, D. J., French, B., Morris, P. B., Silvent, E., & Gordon, R. Y. (2013) · American Heart Journal · doi:10.1016/j.ahj.2013.03.019 · Cited by 37
Cost-effectiveness of a primary care intervention to treat obesity
Tsai, A. G., Wadden, T. A., Volger, S., Sarwer, D. B., Vetter, M., Kumanyika, S., Berkowitz, R. I., Diewald, L. K., Perez, J., Lavenberg, J., et al. (2013) · International Journal of Obesity · doi:10.1038/ijo.2013.94 · Cited by 37
A grape seed procyanidin extract inhibits HDAC activity leading to increased Pparα phosphorylation and target‐gene expression
Downing, L. E., Ferguson, B. S., Rodriguez, K., & Ricketts, M. (2017) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201600347 · Cited by 37
PPARα L162V polymorphism alters the potential of n‐3 fatty acids to increase lipoprotein lipase activity
Rudkowska, I., Caron‐Dorval, D., Verreault, M., Couture, P., Deshaies, Y., Barbier, O., & Vohl, M. (2010) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.200900085 · Cited by 36
Early-onset type 2 diabetes in a Mexican survey: results from the National Health and Nutrition Survey 2006
Jiménez-Corona, A., Rojas, R., Gómez-Pérez, F. J., & Aguilar-Salinas, C. A. (2010) · Salud Pública de México · doi:10.1590/s0036-36342010000700006 · Cited by 36
High Remnant Lipoprotein Predicts Recurrent Cardiovascular Events on Statin Treatment After Acute Coronary Syndrome
Nguyen, S. V., Nakamura, T., & Kugiyama, K. (2014) · Circulation Journal · doi:10.1253/circj.cj-14-0380 · Cited by 34
Effects of GLP-1 receptor agonists on myokine levels and pro-inflammatory cytokines in patients with type 2 diabetes mellitus
Guarnotta, V., Bianco, M. J., Vigneri, E., Panto’, F., Lo Sasso, B., Ciaccio, M., Pizzolanti, G., & Giordano, C. (2021) · Nutrition, Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2021.07.015 · Cited by 36
Metabolic alterations in patients who develop traumatic brain injury (TBI)-induced hypopituitarism
Prodam, F., Gasco, V., Caputo, M., Zavattaro, M., Pagano, L., Marzullo, P., Belcastro, S., Busti, A., Perino, C., Grottoli, S., et al. (2013) · Growth Hormone & IGF Research · doi:10.1016/j.ghir.2013.04.001 · Cited by 35
Characteristics of Inactive Primary Care Patients: Baseline Data from the Activity Counseling Trial
Simons-Morton, D. G., Hogan, P., Dunn, A. L., Pruitt, L., King, A. C., Levine, B. D., & Miller, S. T. (2000) · Preventive Medicine · doi:10.1006/pmed.2000.0733 · Cited by 35
Triglycerides and non-high-density lipoprotein cholesterol and the incidence of cardiovascular disease in an urban Japanese cohort: The Suita study
Okamura, T., Kokubo, Y., Watanabe, M., Higashiyama, A., Ono, Y., Miyamoto, Y., Yoshimasa, Y., & Okayama, A. (2010) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2009.09.012 · Cited by 35
Effects of evolocumab in individuals with type 2 diabetes with and without atherogenic dyslipidemia: an analysis from BANTING and BERSON
Lorenzatti, A. J., Monsalvo, M. L., López, J. A. G., Wang, H., & Rosenson, R. S. (2021) · Cardiovascular Diabetology · doi:10.1186/s12933-021-01287-6 · Cited by 34
Usefulness of plasma glucose and insulin concentrations in identifying patients with insulin resistance
Tuan, C.-Y., Abbasi, F., Lamendola, C., McLaughlin, T., & Reaven, G. (2003) · The American Journal of Cardiology · doi:10.1016/s0002-9149(03)00735-5 · Cited by 34
Managing diabetes in patients with chronic liver disease
Khan, R., Foster, G. R., & Chowdhury, T. A. (2012) · Postgraduate Medicine · doi:10.3810/pgm.2012.07.2574 · Cited by 34
Effect of insulin resistance on postprandial elevations of remnant lipoprotein concentrations in postmenopausal women
Kim, H.-S., Abbasi, F., Lamendola, C., McLaughlin, T., & Reaven, G. M. (2001) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/74.5.592 · Cited by 33
Remnant lipoproteinemia predicts cardiovascular events in patients with type 2 diabetes and chronic kidney disease
Nguyen, S. V., Nakamura, T., Uematsu, M., Fujioka, D., Watanabe, K., Watanabe, Y., Obata, J.-E., Nakamura, K., & Kugiyama, K. (2017) · Journal of Cardiology · doi:10.1016/j.jjcc.2016.04.011 · Cited by 33
Risk of coronary events in Japanese patients with both hypercholesterolemia and type 2 diabetes mellitus on low-dose simvastatin therapy: Implication from Japan Lipid Intervention Trial (J-LIT)
Oikawa, S., Kita, T., Mabuchi, H., Matsuzaki, M., Matsuzawa, Y., Nakaya, N., Saito, Y., Sasaki, J., Shimamoto, K., & Itakura, H. (2007) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2006.04.017 · Cited by 33
Design of a trial to evaluate the impact of clinical pharmacists and community health promoters working with African-Americans and Latinos with Diabetes
Gerber, B. S., Rapacki, L., Castillo, A., Tilton, J., Touchette, D. R., Mihailescu, D., Berbaum, M. L., & Sharp, L. K. (2012) · BMC Public Health · doi:10.1186/1471-2458-12-891 · Cited by 33
The cost effectiveness of statin therapies in Spain in 2010, after the introduction of generics and reference prices
Plans-Rubió, P. (2010) · American Journal Cardiovascular Drugs · doi:10.2165/11539150-000000000-00000 · Cited by 31
From isolated GH deficiency to multiple pituitary hormone deficiency: an evolving continuum - a KIMS analysis
Klose, M., Jonsson, B., Abs, R., Popovic, V, Koltowska-Häggström, M., Saller, B., Feldt-Rasmussen, U., & Kourides, I. (2009) · European Journal of Endocrinology · doi:10.1530/eje-09-0328 · Cited by 31
Statin therapy and decreased incidence of positive Candida cultures among patients with type 2 diabetes mellitus undergoing gastrointestinal surgery.
Spanakis, E. K., Kourkoumpetis, T. K., Livanis, G., Peleg, A. Y., & Mylonakis, E. (2010) · Mayo Clinic Proceedings · doi:10.4065/mcp.2010.0447 · Cited by 31
Measuring insulin sensitivity in postmenopausal women covering a range of glucose tolerance: comparison of indices derived from the oral glucose tolerance test with the euglycemic-hyperinsulinemic clamp
Piché, M.-È., Lemieux, S., Corneau, L., Nadeau, A., Bergeron, J., & Weisnagel, S. J. (2007) · Metabolism · doi:10.1016/j.metabol.2007.04.002 · Cited by 31
A randomized clinical trial evaluating a proprietary mixture of Lactobacillus plantarum strains for lowering cholesterol1
Fuentes, M. C., Lajo, T., Carrión, J. M., & Cuñé, J. (2016) · Mediterranean Journal of Nutrition and Metabolism · doi:10.3233/mnm-160065 · Cited by 31
ANN Prediction of Metabolic Syndrome: a Complex Puzzle that will be Completed
Ivanović, D., Kupusinac, A., Stokić, E., Doroslovački, R., & Ivetić, D. (2016) · Journal of Medical Systems · doi:10.1007/s10916-016-0601-7 · Cited by 31
Behavioral health mediators of the link between posttraumatic stress disorder and dyslipidemia
Dennis, P. A., Ulmer, C. S., Calhoun, P. S., Sherwood, A., Watkins, L. L., Dennis, M. F., & Beckham, J. C. (2014) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2014.05.001 · Cited by 31
Insulin resistance possible risk factor for cognitive impairment in fibromialgic patients
Fava, A., Plastino, M., Cristiano, D., Spanò, A., Cristofaro, S., Opipari, C., Chillà, A., Casalinuovo, F., Colica, C., De Bartolo, M., et al. (2013) · Metabolic Brain Disease · doi:10.1007/s11011-013-9421-3 · Cited by 31
Metabolic syndrome in women with previous gestational diabetes
Kaiser, K., Nielsen, M. F., Kallfa, E., Dubietyte, G., & Lauszus, F. F. (2021) · Scientific Reports · doi:10.1038/s41598-021-90832-0 · Cited by 30
Non‐HDL cholesterol vs. Apo B for risk of coronary heart disease in healthy individuals: the EPIC‐Norfolk prospective population study
Sondermeijer, B. M., Rana, J. S., Arsenault, B. J., Shah, P. K., Kastelein, J. J. P., Wareham, N. J., Boekholdt, S. M., & Khaw, K. (2013) · European Journal of Clinical Investigation · doi:10.1111/eci.12129 · Cited by 30
Body morphology differentially predicts coronary calcium
Allison, M. A., & Michael Wright, C. (2004) · International Journal of Obesity · doi:10.1038/sj.ijo.0802571 · Cited by 30
Malondialdehyde-modified low-density lipoprotein is a predictor of cardiac events in patients with stable angina on lipid-lowering therapy after percutaneous coronary intervention using drug-eluting stent
Ito, T., Fujita, H., Tani, T., & Ohte, N. (2015) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2015.01.026 · Cited by 30
Efficacy of colesevelam on lowering glycemia and lipids
Aggarwal, S., Loomba, R. S., & Arora, R. R. (2012) · Journal of Cardiovascular Pharmacology · doi:10.1097/fjc.0b013e31823a109f · Cited by 30
Association of Metabolically Healthy and Unhealthy Obesity Phenotypes with Oxidative Stress Parameters and Telomere Length in Healthy Young Adult Men. Analysis of the MAGNETIC Study
Lejawa, M., Osadnik, K., Osadnik, T., & Pawlas, N. (2021) · Antioxidants · doi:10.3390/antiox10010093 · Cited by 30
Fenofibrate reduces lipoprotein associated phospholipase A2 mass and oxidative lipids in hypertriglyceridemic subjects with the metabolic syndrome
Rosenson, R. S. (2008) · American Heart Journal · doi:10.1016/j.ahj.2007.12.012 · Cited by 30
Dynamic behavior of metabolic syndrome progression: a comprehensive systematic review on recent discoveries
Bagheri, P., Khalili, D., Seif, M., & Rezaianzadeh, A. (2021) · BMC Endocrine Disorders · doi:10.1186/s12902-021-00716-7 · Cited by 30
Major depressive disorder with anger attacks and subcortical MRI white matter hyperintensities
Iosifescu, D. V., Renshaw, P. F., Dougherty, D. D., Lyoo, I. K., Lee, H. K., Fraguas, R., Cassano, P., Nierenberg, A. A., & Fava, M. (2007) · Journal of Nervous & Mental Disease · doi:10.1097/01.nmd.0000253820.69362.87 · Cited by 29
Effects of personality on self‐rated health in a 1‐year randomized controlled trial of chronic illness self‐management
Jerant, A., Chapman, B., Duberstein, P., & Franks, P. (2010) · British Journal of Health Psychology · doi:10.1348/135910709x464353 · Cited by 29
Metabolic syndrome and endothelial fibrinolytic capacity in obese adults
Van Guilder, G. P., Hoetzer, G. L., Greiner, J. J., Stauffer, B. L., & DeSouza, C. A. (2008) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00564.2007 · Cited by 29
Impact of Metabolic Syndrome among Patients with and without Diabetes Mellitus on Long-Term Outcomes after Percutaneous Coronary Intervention
KASAI, T., MIYAUCHI, K., KURATA, T., OKAZAKI, S., KAJIMOTO, K., KUBOTA, N., & DAIDA, H. (2008) · Hypertension Research · doi:10.1291/hypres.31.235 · Cited by 28
Patterns of Cardiometabolic Health as Midlife Women Transition to Menopause: A Prospective Multiethnic Study
Ward, E., Gold, E. B., Johnson, W. O., Ding, F., Chang, P.-Y., Song, P., El Khoudary, S. R., Karvonen-Gutierrez, C., Ylitalo, K. R., & Lee, J. S. (2019) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2018-00941 · Cited by 29
Cardiovascular Risk Factors in Patients with Addison's Disease: A Comparative Study of South African and Swedish Patients
Ross, I. L., Bergthorsdottir, R., Levitt, N., Dave, J. A., Schatz, D., Marais, D., & Johannsson, G. (2014) · PLoS ONE · doi:10.1371/journal.pone.0090768 · Cited by 29
Prescription Omega-3-Acid Ethyl Esters for the Treatment of Very High Triglycerides
Sadovsky, R., & Kris-Etherton, P. (2009) · Postgraduate Medicine · doi:10.3810/pgm.2009.07.2020 · Cited by 28
Self-citation
Optimizing LDL-C Lowering With Statins
McKenney, J. M. (2004) · American Journal of Therapeutics · doi:10.1097/00045391-200401000-00011 · Cited by 27
Self-citation
Short-term changes in lipoprotein subclasses and C-reactive protein levels of hypertriglyceridemic adults on low-carbohydrate and low-fat diets
Stoernell, C. K., Tangney, C. C., & Rockway, S. W. (2008) · Nutrition Research · doi:10.1016/j.nutres.2008.03.013 · Cited by 27
Physical performance measures in screening for reduced lean body mass in adult females with obesity
El Ghoch, M., Rossi, A. P., Calugi, S., Rubele, S., Soave, F., Zamboni, M., Chignola, E., Mazzali, G., Bazzani, P. V., & Dalle Grave, R. (2018) · Nutrition, Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2018.06.008 · Cited by 26
A Web-Based Intervention for Health Professionals and Patients to Decrease Cardiovascular Risk Attributable to Physical Inactivity: Development Process
Sassen, B., Kok, G., Mesters, I., Crutzen, R., Cremers, A., & Vanhees, L. (2012) · JMIR Research Protocols · doi:10.2196/resprot.1804 · Cited by 26
LDL-cholesterol and insulin are independently associated with body mass index in adult cystic fibrosis patients
Coderre, L., Fadainia, C., Belson, L., Belisle, V., Ziai, S., Maillhot, G., Berthiaume, Y., & Rabasa-Lhoret, R. (2012) · Journal of Cystic Fibrosis · doi:10.1016/j.jcf.2012.03.006 · Cited by 26
The Mediterranean and CHO diets decrease VCAM-1 and E-selectin expression induced by modified low-density lipoprotein in HUVECs
Bellido, C., López-Miranda, J., Pérez-Martínez, P., Paz, E., Marín, C., Gómez, P., Moreno, J. A., Moreno, R., & Pérez-Jiménez, F. (2006) · Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2005.09.007 · Cited by 25
Basic psychological need frustration and health: Prospective associations with sleep quality and cholesterol
Uysal, A., Aykutoglu, B., & Ascigil, E. (2020) · Motivation and Emotion · doi:10.1007/s11031-019-09806-5 · Cited by 25
Metabolic Syndrome and the Risk of Suicide: A Community-Based Integrated Screening Samples Cohort Study
Chang, J.-C., Yen, A. M.-F., Lee, C.-S., Chen, S. L.-S., Chiu, S. Y.-H., Fann, J. C.-Y., & Chen, H.-H. (2013) · Psychosomatic Medicine · doi:10.1097/psy.0000000000000014 · Cited by 25
Effect of varying quantities of lean beef as part of a Mediterranean-style dietary pattern on lipids and lipoproteins: a randomized crossover controlled feeding trial.
Fleming, J. A., Kris-Etherton, P. M., Petersen, K. S., & Baer, D. J. (2021) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/nqaa375 · Cited by 25
The Relationship between Non-HDL Cholesterol and Other Lipid Parameters in Japanese Subjects
Sugimoto, K., Isobe, K., Kawakami, Y., & Yamada, N. (2005) · Journal of Atherosclerosis and Thrombosis · doi:10.5551/jat.12.107 · Cited by 25
Water-based aerobic training successfully improves lipid profile of dyslipidemic women: a randomized controlled trial
Costa, R. R., Pilla, C., Buttelli, A. C. K., Barreto, M. F., Vieiro, P. A., Alberton, C. L., Bracht, C. G., & Kruel, L. F. M. (2018) · Research Quarterly for Exercise and Sport · doi:10.1080/02701367.2018.1441485 · Cited by 25
Lipoprotein particle profiles compared with standard lipids in association with coronary artery calcification in the general Japanese population
Hisamatsu, T., Fujiyoshi, A., Miura, K., Ohkubo, T., Kadota, A., Kadowaki, S., Kadowaki, T., Yamamoto, T., Miyagawa, N., Zaid, M., et al. (2014) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2014.07.019 · Cited by 24
Fructose content of low calorie diets: effect on cardiometabolic risk factors in obese women with polycystic ovarian syndrome: a randomized controlled trial
Johnson, L. K., Holven, K. B., Nordstrand, N., Mellembakken, J. R., Tanbo, T., & Hjelmesæth, J. (2015) · Endocrine Connections · doi:10.1530/ec-15-0047 · Cited by 24
Lowering LDL cholesterol in adults: a prospective, community-based practice initiative
Coodley, G. O., Jorgensen, M., Kirschenbaum, J., Sparks, C., Zeigler, L., & Albertson, B. D. (2008) · The American Journal of Medicine · doi:10.1016/j.amjmed.2008.02.031 · Cited by 23
Risk Charts Illustrating the 10-year Risk of Stroke among Residents of Japanese Rural Communities: The JMS Cohort Study
Ishikawa, S., Matsumoto, M., Kayaba, K., Gotoh, T., Nago, N., Tsutsumi, A., & Kajii, E. (2009) · Journal of Epidemiology · doi:10.2188/jea.je20080092 · Cited by 23
Impaired handgrip exercise-induced brachial artery flow-mediated dilation in young obese males
Slattery, D. J., Stuckless, T. J. R., King, T. J., & Pyke, K. E. (2016) · Applied Physiology, Nutrition, and Metabolism · doi:10.1139/apnm-2015-0459 · Cited by 22
Diagnostic accuracy of the different hormonal tests used for the diagnosis of autonomous cortisol secretion
Araujo-Castro, M., García Cano, A., Jiménez Mendiguchía, L., Escobar-Morreale, H. F., & Valderrábano, P. (2021) · Scientific Reports · doi:10.1038/s41598-021-00011-4 · Cited by 24
Metabolic effects of polycystic ovary syndrome in adolescents
Han, Y., Kim, H. S., Lee, H.-J., Oh, J.-Y., & Sung, Y.-A. (2015) · Annals of Pediatric Endocrinology & Metabolism · doi:10.6065/apem.2015.20.3.136 · Cited by 22
Moderate Consumption of Red Meat, Compared to Soy or Non-Soy Legume, Has No Adverse Effect on Cardio-Metabolic Factors in Patients with Type 2 Diabetes
Hassanzadeh-Rostami, Z., Hemmatdar, Z., Pishdad, G. R., & Faghih, S. (2021) · Experimental and Clinical Endocrinology & Diabetes · doi:10.1055/a-0929-6287 · Cited by 22
Relationship between retinal vascular caliber and coronary artery disease in patients with non-alcoholic fatty liver disease (NAFLD)
Josef, P., Ali, I., Ariel, P., Alon, M., & Nimer, A. (2013) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph10083409 · Cited by 22
Association between reduced daily steps and sarcopenic obesity in treatment-seeking adults with obesity
Kreidieh, D., Itani, L., El Masri, D., Tannir, H., & El Ghoch, M. (2020) · Frontiers in Endocrinology · doi:10.3389/fendo.2020.00022 · Cited by 21
Trait Antagonism and the Progression of Arterial Thickening: Women With Antagonistic Traits Have Similar Carotid Arterial Thickness as Men
Sutin, A. R., Scuteri, A., Lakatta, E. G., Tarasov, K. V., Ferrucci, L., Costa, P. T., Schlessinger, D., Uda, M., & Terracciano, A. (2010) · Hypertension · doi:10.1161/hypertensionaha.110.155317 · Cited by 21
Comparison of atorvastatin versus fenofibrate in reaching lipid targets and influencing biomarkers of endothelial damage in patients with familial combined hyperlipidemia
Arca, M., Montali, A., Pigna, G., Antonini, R., Antonini, T. M., Luigi, P., Fraioli, A., Mastrantoni, M., Maddaloni, M., & Letizia, C. (2007) · Metabolism · doi:10.1016/j.metabol.2007.06.021 · Cited by 21
Psychological well-being and restorative biological processes: HDL-C in older English adults
Soo, J., Kubzansky, L. D., Chen, Y., Zevon, E. S., & Boehm, J. K. (2018) · Social Science & Medicine · doi:10.1016/j.socscimed.2018.05.025 · Cited by 21
Adrenal morphology and associated comorbidities in congenital adrenal hyperplasia
El‐Maouche, D., Hannah‐Shmouni, F., Mallappa, A., Hargreaves, C. J., Avila, N. A., & Merke, D. P. (2019) · Clinical Endocrinology · doi:10.1111/cen.13996 · Cited by 20
Plasma lipid, lipoprotein and apolipoprotein levels in a random population sample of 2875 Hong Kong Chinese adults and their implications (NCEP ATP-III, 2001 guidelines) on cardiovascular risk assessment.
Pang, R. W. C., Tam, S., Janus, E. D., Siu, S. T. S., Ma, O. C. K., Lam, T. H., & Lam, K. S. L. (2006) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2005.05.013 · Cited by 20
Refocusing On Use of Cholesteryl Ester Transfer Protein Inhibitors
Kastelein, J. J. P. (2007) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2007.08.013 · Cited by 20
Effects of insulin on left ventricular function during dynamic exercise in overweight and obese subjects
Sasso, F. C., Carbonara, O., Nasti, R., Marfella, R., Esposito, K., Rambaldi, P., Mansi, L., Salvatore, T., Torella, R., & Cozzolino, D. (2005) · European Heart Journal · doi:10.1093/eurheartj/ehi271 · Cited by 20
Prevalence of Metabolic Syndrome Risk Factors Among Young Adult Asian Indians
Shah, T., Jonnalagadda, S. S., Kicklighter, J. R., Diwan, S., & Hopkins, B. L. (2005) · Journal of Immigrant Health · doi:10.1007/s10903-005-2645-5 · Cited by 19
Predictive Value of Lipoprotein Indices for Residual Risk of Acute Myocardial Infarction and Sudden Death in Men With Low-Density Lipoprotein Cholesterol Levels <120 mg/dl
Tanaka, F., Makita, S., Onoda, T., Tanno, K., Ohsawa, M., Itai, K., Sakata, K., Omama, S.-I., Yoshida, Y., Ogasawara, K., et al. (2013) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2013.05.049 · Cited by 19
Medical Correlates of Chronic Multisymptom Illness in Gulf War Veterans
Blanchard, M., Molina-Vicenty, H. D., Stein, P. K., Li, X., Karlinsky, J., Alpern, R., Reda, D. J., & Toomey, R. (2019) · The American Journal of Medicine · doi:10.1016/j.amjmed.2018.11.045 · Cited by 19
Effects of an internet-based lifestyle intervention on cardio-metabolic risks and stress in Korean workers with metabolic syndrome: A controlled trial
Kim, C.-J., Schlenk, E. A., Kang, S.-W., & Park, J.-B. (2015) · Patient Education and Counseling · doi:10.1016/j.pec.2014.10.013 · Cited by 19
Risk factors for cardiovascular disease among the homeless and in the general population of the city of Porto, Portugal
Oliveira, L. D. P., Pereira, M. L., Azevedo, A., & Lunet, N. (2012) · Cadernos de Saúde Pública · doi:10.1590/s0102-311x2012000800010 · Cited by 18
Effect of raloxifene on serum triglycerides in postmenopausal women: influence of predisposing factors for hypertriglyceridemia.
Mosca, L. (2001) · Clinical Therapeutics · doi:10.1016/s0149-2918(01)80127-2 · Cited by 18
Dietary interventions that lower lipoproteins containing apolipoprotein C-III are more effective in whites than in blacks: results of the OmniHeart trial.
Furtado, J. D., Campos, H., Sumner, A. E., Appel, L. J., Carey, V. J., & Sacks, F. M. (2010) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.2009.28532 · Cited by 18
The role of psychobiological and neuroendocrine mechanisms in appetite regulation and obesity
Paspala, I., Katsiki, N., Kapoukranidou, D., Mikhailidis, D. P., & Tsiligiroglou-Fachantidou, A. (2012) · The Open Cardiovascular Medicine Journal · doi:10.2174/1874192401206010147 · Cited by 18
Associations between sex hormone binding globulin and metabolic syndrome parameters in premenopausal obese women
Akin, F., Bastemir, M., Alkis, E., & Kaptanoglu, B. (2008) · Indian Journal of Medical Sciences · doi:10.4103/0019-5359.44020 · Cited by 18
A suplementação de L-carnitina não promove alterações na taxa metabólica de repouso e na utilização dos substratos energéticos em indivíduos ativos
Coelho, C. D. F., Mota, J. F., Ravagnani, F. C. D. P., & Burini, R. C. (2010) · Arquivos Brasileiros de Endocrinologia & Metabologia · doi:10.1590/s0004-27302010000100007 · Cited by 17
Longitudinal relationship between physical activity and cardiometabolic factors in overweight and obese adults
Choo, J., Elci, O. U., Yang, K., Turk, M. W., Styn, M. A., Sereika, S. M., Music, E., & Burke, L. E. (2010) · European Journal of Applied Physiology · doi:10.1007/s00421-009-1203-6 · Cited by 17
Clinical MRI cutoff points for predicting lacunar stroke may not exist: need for a grading rather than a dichotomizing system
Bang, O. Y., Yeo, S. H., Yoon, J. H., Seok, J. I., Sheen, S. S., Yoon, S. R., Kim, G. M., Chung, C. S., & Lee, K. H. (2007) · Cerebrovascular Diseases · doi:10.1159/000110422 · Cited by 16
Efficacy of high intensity atorvastatin versus moderate intensity atorvastatin for acute coronary syndrome patients with diabetes mellitus
Liu, Z., Xu, Y., Hao, H., Yin, C., Xu, J., Li, J., Wang, Y., & Xu, D. (2016) · International Journal of Cardiology · doi:10.1016/j.ijcard.2016.07.140 · Cited by 16
Obesity in Older Adults – A Growing Problem
Villareal, D. T., & Shah, K. (2009) · Handbook of Clinical Nutrition and Aging · doi:10.1007/978-1-60327-385-5_15 · Cited by 18
Trends in Metabolic Syndrome and Gene Networks in Human and Rodent Models
Kraja, A., Province, M., Huang, P., Jarvis, J., Rice, T., Cheverud, J., & Rao, D. (2008) · Endocrine‚ Metabolic & Immune Disorders-Drug Targets · doi:10.2174/187153008785700145 · Cited by 15
Clinical Use of a Carbohydrate-Restricted Diet to Treat the Dyslipidemia of the Metabolic Syndrome
Hickey, J. T., Hickey, L., Yancy, W. S., Hepburn, J., & Westman, E. C. (2003) · Metabolic Syndrome and Related Disorders · doi:10.1089/154041903322716705 · Cited by 14
Association Between Poverty and Appropriate Statin Prescription for the Treatment of Hyperlipidemia in the United States: An Analysis From the ACC NCDR PINNACLE Registry
Tanguturi, V. K., Kennedy, K. F., Virani, S. S., Maddox, T. M., Armstrong, K., & Wasfy, J. H. (2020) · Cardiovascular Revascularization Medicine · doi:10.1016/j.carrev.2019.12.026 · Cited by 15
The Impact of Pravastatin Therapy on Long-Term Outcome in Patients With Metabolic Syndrome Undergoing Complete Coronary Revascularization
Kasai, T., Miyauchi, K., Kajimoto, K., Kubota, N., Kurata, T., Amano, A., & Daida, H. (2009) · Circulation Journal · doi:10.1253/circj.cj-09-0122 · Cited by 13
Dose-dependent effect of niceritrol on plasma lipoprotein-a
Teramoto, T., Yamada, N., Shimano, H., Oka, Y., Itakura, H., Saito, Y., Morisaki, N., Shirai, K., Ishikawa, T., Tada, N., et al. (1996) · Scandinavian Journal of Clinical and Laboratory Investigation · doi:10.3109/00365519609090588 · Cited by 13
Effectiveness of home pharmaceutical interventions in metabolic syndrome: a randomized controlled trial
Azevedo, M. D. G. B. D., Pedrosa, R. S., Aoqui, C. M., Martins, R. R., & Nagashima Junior, T. (2017) · Brazilian Journal of Pharmaceutical Sciences · doi:10.1590/s2175-97902017000216089 · Cited by 13
Dietary management for dyslipidemia in liver transplant recipients
PINTO, A. S., Postgraduate Program in Surgical Sciences, B., CHEDID, M. F., GUERRA, L. T., CABELEIRA, D. D., KRUEL, C. D. P., Division of Gastrointestinal Surgery and Liver and Pancreas Transplantation, B., & Federal University of Rio Grande do Sul, B. (2016) · ABCD. Arquivos Brasileiros de Cirurgia Digestiva (São Paulo) · doi:10.1590/0102-6720201600040008 · Cited by 12
Comparison of cardiovascular disease risk associated with 3 lipid measures in Japanese adults
Takeuchi, T., Nemoto, K.-I., Takahashi, O., Urayama, K. Y., Deshpande, G. A., & Izumo, H. (2014) · Journal of Clinical Lipidology · doi:10.1016/j.jacl.2014.06.005 · Cited by 12
Dyslipidemia incidence and the trend of lipid parameters changes in women with history of gestational diabetes: a 15-year follow-up study
Minooee, S., Ramezani Tehrani, F., Rahmati, M., Mansournia, M. A., & Azizi, F. (2017) · Endocrine · doi:10.1007/s12020-017-1413-3 · Cited by 12
Statins for Cardiovascular Prevention According to Different Strategies: A Cost Analysis
Ito, M. K., Nanchen, D., Rodondi, N., Paccaud, F., Waeber, G., Vollenweider, P., & Marques-Vidal, P. (2011) · American Journal Cardiovascular Drugs · doi:10.2165/11586760-000000000-00000 · Cited by 11
Novel strategies for managing dyslipidemia: treatment beyond statins
Ling, H., Burns, T. L., & Hilleman, D. E. (2012) · Postgraduate Medicine · doi:10.3810/pgm.2012.11.2612 · Cited by 10
Correlates of Adverse Outcomes in Abdominally Obese Individuals: Findings from the Five-Year Followup of the Population-Based Study of Health in Pomerania
Friedrich, N., Schneider, H. J., John, U., Dörr, M., Baumeister, S. E., Homuth, G., Völker, U., & Wallaschofski, H. (2013) · Journal of Obesity · doi:10.1155/2013/762012 · Cited by 10
Do age and baseline LDL cholesterol levels determine the effect of regular exercise on plasma lipoprotein cholesterol and apolipoprotein B levels?
Angelopoulos, T. J., Sivo, S. A., Kyriazis, G. A., Caplan, J. D., Zoeller, R. F., Lowndes, J., Seip, R. L., & Thompson, P. D. (2007) · European Journal of Applied Physiology · doi:10.1007/s00421-007-0537-1 · Cited by 6
Dietary Complex Carbohydrates and Low Glycemic Index/Load Decrease Levels of Specific Metabolic Syndrome/Cardiovascular Disease Risk Factors
Gastrich, M. D., Lasser, N. L., Wien, M., & Bachmann, G. (2008) · Topics in Clinical Nutrition · doi:10.1097/01.tin.0000312083.76447.8d · Cited by 6
Impact of the statin escape phenomenon on long-term clinical outcomes in patients with acute myocardial infarction: Subgroup analysis of the Nagoya Acute Myocardial Infarction Study (NAMIS)
Ota, T., Ishii, H., Suzuki, S., Shibata, Y., Tatami, Y., Harata, S., Shimbo, Y., Takayama, Y., Tanaka, A., Kawamura, Y., et al. (2015) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2015.07.012 · Cited by 5

Authors: Grundy, S. M., Bilheimer, D. W., Chait, A., Clark, L. T., Denke, M. A., Havel, R. J., Hazzard, W. R., Hulley, S. B., Hunninghake, D. B., Kreisberg, R. A., Kris‐Etherton, P. M., McKenney, J. M., Newman, M. A., Schaefer, E. J., Sobel, B. E., Somelofski, C. A., Weinstein, M. C., Brewer, H. B., Cleeman, J. I., Donato, K. A., Ernst, N. D., Hoeg, J. M., Rifkind, B. M., Rossouw, J., Sempos, C. T., Gallivan, J. M., Harris, M. N., & Quint-Adler, L.
Venue: JAMA
Publisher: American Medical Association (AMA)
Published: 1993-06-16
Volume: 269
Issue: 23
Pages: 3015
ISSN: 0002-9955 (ISSN-L)
0098-7484
DOI: 10.1001/jama.269.23.3015
OpenAlex: W4249825849
Cited by: 27,947
References: 0
FWCI: 282.04
Type: journal article
Language: en
Open access: closed

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.

Summary of the Second Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel II)

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Self-check

Citations

Cited by

Metadata

Record

About these checks

Data sources