The Hallmarks of Aging

Cites (305)

Items 201–303 of 303

1. Longevity in Mice Is Promoted by Probiotic-Induced Suppression of Colonic Senescence Dependent on Upregulation of Gut Bacterial Polyamine Production
   Matsumoto, Mitsuharu, Kurihara, Shin, Kibe, Ryoko, Ashida, Hisashi, Benno, Yoshimi · 2011 · PLoS ONE
2. Overexpression of the small mitochondrial Hsp22 extends Drosophila life span and increases resistance to oxidative stress
   Morrow, Geneviève, Samson, Mélanie, Michaud, Sébastien, M. Tanguay, Robert · 2004 · The FASEB Journal
3. If Started Early in Life, Metformin Treatment Increases Life Span and Postpones Tumors in Female SHR Mice
   Anisimov, Vladimir N., Berstein, Lev M., Popovich, Irina G., Zabezhinski, Mark A., Egormin, Peter A., Piskunova, Tatiana S., Semenchenko, Anna V., Tyndyk, Margarita L., Yurova, Maria N., Kovalenko, Irina G. et al. · 2011 · Aging
4. Heterochromatin formation promotes longevity and represses ribosomal RNA synthesis
   Larson, Kimberly, Yan, Shian-Jang, Tsurumi, Amy, Liu, Jacqueline, Zhou, Jun, Gaur, Kriti, Guo, Dongdong, Eickbush, Thomas H., Li, Willis X. · 2012 · PLoS Genetics
5. Progerin and telomere dysfunction collaborate to trigger cellular senescence in normal human fibroblasts
   Cao, Kan, Blair, Cecilia D., Faddah, Dina A., Kieckhaefer, Julia E., Olive, Michelle, Erdos, Michael R., Nabel, Elizabeth G., Collins, Francis S. · 2011 · Journal of Clinical Investigation
6. Mitochondrial DNA mutations in disease and aging
   Park, Chan Bae, Larsson, Nils-Göran · 2011 · Journal of Cell Biology
7. Ageing-related chromatin defects through loss of the NURD complex
   Pegoraro, Gianluca, Kubben, Nard, Wickert, Ute, Göhler, Heike, Hoffmann, Katrin, Misteli, Tom · 2009 · Nature Cell Biology
8. Nuclear lamina defects cause ATM-dependent NF-κB activation and link accelerated aging to a systemic inflammatory response
   Osorio, Fernando G., Bárcena, Clea, Soria-Valles, Clara, Ramsay, Andrew J., de Carlos, Félix, Cobo, Juan, Fueyo, Antonio, Freije, José M.P., López-Otín, Carlos · 2012 · Genes & Development
9. Lifespan extension in C. elegans by a molecular chaperone dependent upon insulin‐like signals
   Walker, Glenda A., Lithgow, Gordon J. · 2003 · Aging Cell
10. A farnesyltransferase inhibitor improves disease phenotypes in mice with a Hutchinson-Gilford progeria syndrome mutation
    Yang, S. H. · 2006 · Journal of Clinical Investigation
11. Disruption of telomerase trafficking by TCAB1 mutation causes dyskeratosis congenita
    Zhong, Franklin, Savage, Sharon A., Shkreli, Marina, Giri, Neelam, Jessop, Lea, Myers, Timothy, Chen, Renee, Alter, Blanche P., Artandi, Steven E. · 2011 · Genes & Development
12. SirT1 regulates adipose tissue inflammation
    Gillum, Matthew P., Kotas, Maya E., Erion, Derek M., Kursawe, Romy, Chatterjee, Paula, Nead, Kevin T., Muise, Eric S., Hsiao, Jennifer J., Frederick, David W., Yonemitsu, Shin et al. · 2011 · Diabetes
13. Histone demethylase UTX-1 regulates C. elegans life span by targeting the insulin/IGF-1 signaling pathway
    Jin, Chunyu, Li, Jing, Green, Christopher D., Yu, Xiaoming, Tang, Xia, Han, Dali, Xian, Bo, Wang, Dan, Huang, Xinxin, Cao, Xiongwen et al. · 2011 · Cell Metabolism
14. SIRT3, a pivotal actor in mitochondrial functions: metabolism, cell death and aging
    Albert Giralt, Francesc Villarroya · 2012 · Biochemical Journal
15. Oncogene-induced senescence: the bright and dark side of the response
    Gorgoulis, Vassilis G, Halazonetis, Thanos D · 2010 · Current Opinion in Cell Biology
16. Short Telomeres are Sufficient to Cause the Degenerative Defects Associated with Aging
    Armanios, Mary, Alder, Jonathan K., Parry, Erin M., Karim, Baktiar, Strong, Margaret A., Greider, Carol W. · 2009 · The American Journal of Human Genetics
17. Global heterochromatin loss: a unifying theory of aging?
    Tsurumi, Amy, Li, Willis · 2012 · Epigenetics
18. Human aging is characterized by focused changes in gene expression and deregulation of alternative splicing
    Harries, Lorna W., Hernandez, Dena, Henley, William, Wood, Andrew R., Holly, Alice C., Bradley‐Smith, Rachel M., Yaghootkar, Hanieh, Dutta, Ambarish, Murray, Anna, Frayling, Timothy M. et al. · 2011 · Aging Cell
19. Emerging models and paradigms for stem cell ageing
    Jones, D. Leanne, Rando, Thomas A. · 2011 · Nature Cell Biology
20. CHIP deficiency decreases longevity, with accelerated aging phenotypes accompanied by altered protein quality control
    Min, Jin-Na, Whaley, Ryan A., Sharpless, Norman E., Lockyer, Pamela, Portbury, Andrea L., Patterson, Cam · 2008 · Molecular and Cellular Biology
21. Hsp72 preserves muscle function and slows progression of severe muscular dystrophy
    Gehrig, Stefan M., van der Poel, Chris, Sayer, Timothy A., Schertzer, Jonathan D., Henstridge, Darren C., Church, Jarrod E., Lamon, Severine, Russell, Aaron P., Davies, Kay E., Febbraio, Mark A. et al. · 2012 · Nature
22. Mitochondrial DNA mutations induce mitochondrial dysfunction, apoptosis and sarcopenia in skeletal muscle of mitochondrial DNA mutator mice
    Hiona, Asimina, Sanz, Alberto, Kujoth, Gregory C., Pamplona, Reinald, Seo, Arnold Y., Hofer, Tim, Someya, Shinichi, Miyakawa, Takuya, Nakayama, Chie, Samhan-Arias, Alejandro K. et al. · 2010 · PLoS ONE
23. Immune surveillance of senescent cells--biological significance in cancer- and non-cancer pathologies
    Hoenicke, L., Zender, L. · 2012 · Carcinogenesis
24. Novel roles for A-type lamins in telomere biology and the DNA damage response pathway
    Gonzalez‐Suarez, Ignacio, Redwood, Abena B, Perkins, Stephanie M, Vermolen, Bart, Lichtensztejin, Daniel, Grotsky, David A, Morgado‐Palacin, Lucia, Gapud, Eric J, Sleckman, Barry P, Sullivan, Teresa et al. · 2009 · The EMBO Journal
25. Increased expression of BubR1 protects against aneuploidy and cancer and extends healthy lifespan
    Baker, Darren J., Dawlaty, Meelad M., Wijshake, Tobias, Jeganathan, Karthik B., Malureanu, Liviu, van Ree, Janine H., Crespo-Diaz, Ruben, Reyes, Santiago, Seaburg, Lauren, Shapiro, Virginia et al. · 2013 · Nature Cell Biology
26. Rapamycin ameliorates age-dependent obesity associated with increased mTOR signaling in hypothalamic POMC neurons
    Yang, Shi-Bing, Tien, An-Chi, Boddupalli, Gayatri, Xu, Allison W., Jan, Yuh Nung, Jan, Lily Yeh · 2012 · Neuron
27. Caloric restriction or catalase inactivation extends yeast chronological lifespan by inducing H 2 O 2 and superoxide dismutase activity
    Mesquita, Ana, Weinberger, Martin, Silva, Alexandra, Sampaio-Marques, Belém, Almeida, Bruno, Leão, Cecília, Costa, Vítor, Rodrigues, Fernando, Burhans, William C., Ludovico, Paula · 2010 · Proceedings of the National Academy of Sciences
28. Heterochronic parabiosis for the study of the effects of aging on stem cells and their niches
    Conboy, Irina M., Rando, Thomas A. · 2012 · Cell Cycle
29. Histone H4 lysine 16 hypoacetylation is associated with defective DNA repair and premature senescence in Zmpste24-deficient mice
    Krishnan, Vaidehi, Chow, Maggie Zi Ying, Wang, Zimei, Zhang, Le, Liu, Baohua, Liu, Xinguang, Zhou, Zhongjun · 2011 · Proceedings of the National Academy of Sciences
30. Negative regulation of inflammation by SIRT1
    Xie, Jun, Zhang, Xiaoming, Zhang, Li · 2013 · Pharmacological Research
31. Muscle-derived stem/progenitor cell dysfunction limits healthspan and lifespan in a murine progeria model
    Lavasani, Mitra, Robinson, Andria R., Lu, Aiping, Song, Minjung, Feduska, Joseph M., Ahani, Bahar, Tilstra, Jeremy S., Feldman, Chelsea H., Robbins, Paul D., Niedernhofer, Laura J. et al. · 2012 · Nature Communications
32. Somatic progenitor cell vulnerability to mitochondrial DNA mutagenesis underlies progeroid phenotypes in Polg mutator mice
    Ahlqvist, Kati J., Hämäläinen, Riikka H., Yatsuga, Shuichi, Uutela, Marko, Terzioglu, Mügen, Götz, Alexandra, Forsström, Saara, Salven, Petri, Angers-Loustau, Alexandre, Kopra, Outi H. et al. · 2012 · Cell Metabolism
33. Elevated proteasome capacity extends replicative lifespan in Saccharomyces cerevisiae
    Kruegel, Undine, Robison, Brett, Dange, Thomas, Kahlert, Günther, Delaney, Joe R., Kotireddy, Soumya, Tsuchiya, Mitsuhiro, Tsuchiyama, Scott, Murakami, Christopher J., Schleit, Jennifer et al. · 2011 · PLoS Genetics
34. HSF-1 regulators DDL-1/2 link insulin-like signaling to heat-shock responses and modulation of longevity
    Chiang, Wei-Chung, Ching, Tsui-Ting, Lee, Hee Chul, Mousigian, Carol, Hsu, Ao-Lin · 2012 · Cell
35. Targeted Gene Correction of Laminopathy-Associated LMNA Mutations in Patient-Specific iPSCs
    Guang‐Hui Liu, Keiichiro Suzuki, Jing Tao Qu, Ignacio Sancho-Martinez, Fei Yi, Mo Li, Sachin Kumar, Emmanuel Nivet, Jessica Kim, Rupa Devi Soligalla et al. · 2011 · Cell stem cell
36. Metabolic networks of longevity
    Houtkooper, Riekelt H., Williams, Robert W., Auwerx, Johan · 2010 · Cell
37. Polycomb Repressive Complex 2 and Trithorax modulate Drosophila longevity and stress resistance
    Siebold, Alex P., Banerjee, Rakhee, Tie, Feng, Kiss, Daniel L., Moskowitz, Jacob, Harte, Peter J. · 2010 · Proceedings of the National Academy of Sciences
38. Sirtuins, Aging, and Metabolism
    Leonard Guarente · 2011 · Cold Spring Harbor Symposia on Quantitative Biology
39. Delayed and Accelerated Aging Share Common Longevity Assurance Mechanisms
    Schumacher, Björn, van der Pluijm, Ingrid, Moorhouse, Michael J., Kosteas, Theodore, Robinson, Andria Rasile, Suh, Yousin, Breit, Timo M., van Steeg, Harry, Niedernhofer, Laura J., van IJcken, Wilfred et al. · 2008 · PLoS Genetics
40. Evaluation of Resveratrol, Green Tea Extract, Curcumin, Oxaloacetic Acid, and Medium-Chain Triglyceride Oil on Life Span of Genetically Heterogeneous Mice
    Strong, R., Miller, R. A., Astle, C. M., Baur, J. A., de Cabo, R., Fernandez, E., Guo, W., Javors, M., Kirkland, J. L., Nelson, J. F. et al. · 2013 · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences
41. dFOXO‐independent effects of reduced insulin‐like signaling in Drosophila
    Slack, Cathy, Giannakou, Maria E., Foley, Andrea, Goss, Martin, Partridge, Linda · 2011 · Aging Cell
42. Histone methylation makes its mark on longevity
    Han, Shuo, Brunet, Anne · 2012 · Trends in Cell Biology
43. Review: a meta‐analysis of GWAS and age‐associated diseases
    Jeck, William R., Siebold, Alex P., Sharpless, Norman E. · 2012 · Aging Cell
44. From sirtuin biology to human diseases: an update
    Sebastián, Carlos, Satterstrom, F.Kyle, Haigis, Marcia C., Mostoslavsky, Raul · 2012 · Journal of Biological Chemistry
45. Telomere length behaves as biomarker of somatic redundancy rather than biological age
    Boonekamp, Jelle J., Simons, Mirre J. P., Hemerik, Lia, Verhulst, Simon · 2013 · Aging Cell
46. Small-molecule proteostasis regulators for protein conformational diseases
    Calamini, Barbara, Silva, Maria Catarina, Madoux, Franck, Hutt, Darren M, Khanna, Shilpi, Chalfant, Monica A, Saldanha, S Adrian, Hodder, Peter, Tait, Bradley D, Garza, Dan et al. · 2012 · Nature Chemical Biology
47. Mitochondrial aging is accelerated by anti-retroviral therapy through the clonal expansion of mtDNA mutations
    Payne, Brendan A I, Wilson, Ian J, Hateley, Charlotte A, Horvath, Rita, Santibanez-Koref, Mauro, Samuels, David C, Price, D Ashley, Chinnery, Patrick F · 2011 · Nature Genetics
48. Hormesis, cellular stress response and vitagenes as critical determinants in aging and longevity
    Calabrese, Vittorio, Cornelius, Carolin, Cuzzocrea, Salvatore, Iavicoli, Ivo, Rizzarelli, Enrico, Calabrese, Edward J. · 2011 · Molecular Aspects of Medicine
49. Random point mutations with major effects on protein-coding genes are the driving force behind premature aging in mtDNA mutator mice
    Edgar, Daniel, Shabalina, Irina, Camara, Yolanda, Wredenberg, Anna, Calvaruso, Maria Antonietta, Nijtmans, Leo, Nedergaard, Jan, Cannon, Barbara, Larsson, Nils-Göran, Trifunovic, Aleksandra · 2009 · Cell Metabolism
50. Polyamine-rich food decreases age-associated pathology and mortality in aged mice
    Soda, Kuniyasu, Dobashi, Yoh, Kano, Yoshihiko, Tsujinaka, Shingo, Konishi, Fumio · 2009 · Experimental Gerontology
51. Ultra-deep sequencing of mouse mitochondrial DNA: mutational patterns and their origins
    Ameur, Adam, Stewart, James B., Freyer, Christoph, Hagström, Erik, Ingman, Max, Larsson, Nils-Göran, Gyllensten, Ulf · 2011 · PLoS Genetics
52. ω-6 Polyunsaturated fatty acids extend life span through the activation of autophagy
    O'Rourke, Eyleen J., Kuballa, Petric, Xavier, Ramnik, Ruvkun, Gary · 2013 · Genes & Development
53. Decreased Proteasomal Activity Causes Age-Related Phenotypes and Promotes the Development of Metabolic Abnormalities
    Tomaru, Utano, Takahashi, Satomi, Ishizu, Akihiro, Miyatake, Yukiko, Gohda, Aya, Suzuki, Sayuri, Ono, Ayako, Ohara, Jiro, Baba, Tomohisa, Murata, Shigeo et al. · 2012 · The American Journal of Pathology
54. The Free Radical Theory of Aging: Effect of Age on Serum Copper Levels
    Denham Harman · 1965 · Journal of Gerontology
55. The C. elegans microRNA mir-71 acts in neurons to promote germline-mediated longevity through regulation of DAF-16/FOXO
    Boulias, Konstantinos, Horvitz, H. Robert · 2012 · Cell Metabolism
56. Dietary restriction and aging: a unifying perspective
    Piper, Matthew D.W., Partridge, Linda, Raubenheimer, David, Simpson, Stephen J. · 2011 · Cell Metabolism
57. Age-related somatic structural changes in the nuclear genome of human blood cells
    Forsberg, Lars A., Rasi, Chiara, Razzaghian, Hamid R., Pakalapati, Geeta, Waite, Lindsay, Thilbeault, Krista Stanton, Ronowicz, Anna, Wineinger, Nathan E., Tiwari, Hemant K., Boomsma, Dorret et al. · 2012 · The American Journal of Human Genetics
58. Mice deficient in both Mn superoxide dismutase and glutathione peroxidase-1 have increased oxidative damage and a greater incidence of pathology but no reduction in longevity
    Zhang, Y., Ikeno, Y., Qi, W., Chaudhuri, A., Li, Y., Bokov, A., Thorpe, S. R., Baynes, J. W., Epstein, C., Richardson, A. et al. · 2009 · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences
59. The let-7-Imp axis regulates ageing of the Drosophila testis stem-cell niche
    Toledano, Hila, D’Alterio, Cecilia, Czech, Benjamin, Levine, Erel, Jones, D. Leanne · 2012 · Nature
60. Mitochondrial uncoupling and lifespan
    Mookerjee, Shona A., Divakaruni, Ajit S., Jastroch, Martin, Brand, Martin D. · 2010 · Mechanisms of Ageing and Development
61. Regulation of Caenorhabditis elegans lifespan by sir-2.1 transgenes
    Viswanathan, Mohan, Guarente, Leonard · 2011 · Nature
62. Age-associated inflammation inhibits epidermal stem cell function
    Doles, Jason, Storer, Mekayla, Cozzuto, Luca, Roma, Guglielmo, Keyes, William M. · 2012 · Genes & Development
63. Néstor–Guillermo progeria syndrome: A novel premature aging condition with early onset and chronic development caused by BANF1 mutations
    Cabanillas, Rubén, Cadiñanos, Juan, Villameytide, José A.F., Pérez, Mercedes, Longo, Jesús, Richard, José M., Álvarez, Rebeca, Durán, Noelia S., Illán, Rafael, González, Daniel J. et al. · 2011 · American Journal of Medical Genetics Part A
64. Cell-by-cell scanning of whole mitochondrial genomes in aged human heart reveals a significant fraction of myocytes with clonally expanded deletions
    Khrapko, K., Bodyak, N., Thilly, W. G., van Orsouw, N. J., Zhang, X., Coller, H. A., Perls, T. T., Upton, M., Vijg, J., Wei, J. Y. · 1999 · Nucleic Acids Research
65. Nuclear envelope defects cause stem cell dysfunction in premature-aging mice
    Espada, Jesús, Varela, Ignacio, Flores, Ignacio, Ugalde, Alejandro P., Cadiñanos, Juan, Pendás, Alberto M., Stewart, Colin L., Tryggvason, Karl, Blasco, María A., Freije, José M.P. et al. · 2008 · The Journal of Cell Biology
66. A Mouse Model of Accelerated Liver Aging Caused by a Defect in DNA Repair
    Siobhán Q. Gregg, Verónica Gutiérrez, Andria Rasile Robinson, Tyler B. Woodell, Atsunori Nakao, Mark A. Ross, George K. Michalopoulos, Lora Heather Rigatti, Carrie E. Rothermel, Irene Kamileri et al. · 2011 · Hepatology
67. mRNA decay factor AUF1 maintains normal aging, telomere maintenance, and suppression of senescence by activation of telomerase transcription
    Pont, Adam R., Sadri, Navid, Hsiao, Susan J., Smith, Susan, Schneider, Robert J. · 2012 · Molecular Cell
68. Role of shelterin in cancer and aging
    Martínez, Paula, Blasco, Maria A. · 2010 · Aging Cell
69. Genome-environment interactions that modulate aging: powerful targets for drug discovery
    de Magalhães, João Pedro, Wuttke, Daniel, Wood, Shona H., Plank, Michael, Vora, Chintan · 2012 · Pharmacological Reviews
70. Identification of MOAG-4/SERF as a regulator of age-related proteotoxicity
    van Ham, Tjakko J., Holmberg, Mats A., van der Goot, Annemieke T., Teuling, Eva, Garcia-Arencibia, Moises, Kim, Hyun-eui, Du, Deguo, Thijssen, Karen L., Wiersma, Marit, Burggraaff, Rogier et al. · 2010 · Cell
71. Insulin-like growth factor 1 treatment extends longevity in a mouse model of human premature aging by restoring somatotroph axis function
    Mariño, Guillermo, Ugalde, Alejandro P., Fernández, Álvaro F., Osorio, Fernando G., Fueyo, Antonio, Freije, José M. P., López-Otín, Carlos · 2010 · Proceedings of the National Academy of Sciences
72. Next-generation sequencing in aging research: Emerging applications, problems, pitfalls and possible solutions
    João Pedro de Magalhães, Caleb E. Finch, Georges E. Janssens · 2009 · Ageing Research Reviews
73. The role of telomeres and telomerase in stem cell aging
    Flores, Ignacio, Blasco, Maria A. · 2010 · FEBS Letters
74. EGF signalling activates the ubiquitin proteasome system to modulate C. elegans lifespan
    Gang Liu, Jason V. Rogers, Coleen T. Murphy, Christopher Rongo · 2011 · The EMBO Journal
75. Epigenetic regulation of aging stem cells
    Pollina, E A, Brunet, A · 2011 · Oncogene
76. The aged microenvironment contributes to the age-related functional defects of CD4 T cells in mice
    Lefebvre, Julie S., Maue, Alexander C., Eaton, Sheri M., Lanthier, Paula A., Tighe, Michael, Haynes, Laura · 2012 · Aging Cell
77. A steroid receptor-microRNA switch regulates life span in response to signals from the gonad
    Shen, Yidong, Wollam, Joshua, Magner, Daniel, Karalay, Oezlem, Antebi, Adam · 2012 · Science
78. Tissue regenerative delays and synthetic lethality in adult mice after combined deletion of Atr and Trp53
    Ruzankina, Yaroslava, Schoppy, David W, Asare, Amma, Clark, Carolyn E, Vonderheide, Robert H, Brown, Eric J · 2009 · Nature Genetics
79. Chromosome-specific accumulation of aneuploidy in the aging mouse brain
    Faggioli, Francesca, Wang, Tao, Vijg, Jan, Montagna, Cristina · 2012 · Human Molecular Genetics
80. Anti‐aging activity of the Ink4/Arf locus
    Matheu, Ander, Maraver, Antonio, Collado, Manuel, Garcia‐Cao, Isabel, Cañamero, Marta, Borras, Consuelo, Flores, Juana M., Klatt, Peter, Viña, Jose, Serrano, Manuel · 2009 · Aging Cell
81. Respiratory uncoupling in skeletal muscle delays death and diminishes age-related disease
    Gates, Allison C., Bernal-Mizrachi, Carlos, Chinault, Sharon L., Feng, Chu, Schneider, Jochen G., Coleman, Trey, Malone, James P., Townsend, R. Reid, Chakravarthy, Manu V., Semenkovich, Clay F. · 2007 · Cell Metabolism
82. FoxO1 is involved in the antineoplastic effect of calorie restriction
    Yamaza, Haruyoshi, Komatsu, Toshimitsu, Wakita, Saori, Kijogi, Carole, Park, Seongjoon, Hayashi, Hiroko, Chiba, Takuya, Mori, Ryoichi, Furuyama, Tatsuo, Mori, Nozomu et al. · 2010 · Aging Cell
83. Roles of SIRT1 in the acute and restorative phases following induction of inflammation
    Zhang, Zhiyong, Lowry, Stephen F., Guarente, Leonard, Haimovich, Beatrice · 2010 · Journal of Biological Chemistry
84. Long-term p110α PI3K inactivation exerts a beneficial effect on metabolism
    Foukas, Lazaros C., Bilanges, Benoit, Bettedi, Lucia, Pearce, Wayne, Ali, Khaled, Sancho, Sara, Withers, Dominic J., Vanhaesebroeck, Bart · 2013 · EMBO Molecular Medicine
85. p53 deletion impairs clearance of chromosomal-instable stem cells in aging telomere-dysfunctional mice
    Begus-Nahrmann, Yvonne, Lechel, André, Obenauf, Anna C, Nalapareddy, Kodandaramireddy, Peit, Elvira, Hoffmann, Eva, Schlaudraff, Falk, Liss, Birgit, Schirmacher, Peter, Kestler, Hans et al. · 2009 · Nature Genetics
86. Direct mutation analysis by high-throughput sequencing: From germline to low-abundant, somatic variants
    Michael C. Gundry, Jan Vijg · 2011 · Mutation research. Fundamental and molecular mechanisms of mutagenesis
87. The biology of aging: 1985–2010 and beyond
    George M. Martin · 2011 · The FASEB Journal
88. Mitochondrial longevity pathways
    Raffaello, Anna, Rizzuto, Rosario · 2011 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
89. Effects of aging and methionine restriction applied at old age on ROS generation and oxidative damage in rat liver mitochondria
    Sanchez-Roman, Inés, Gómez, Alexia, Pérez, Irene, Sanchez, Carlota, Suarez, Henar, Naudí, Alba, Jové, Mariona, Lopez-Torres, Mónica, Pamplona, Reinald, Barja, Gustavo · 2012 · Biogerontology
90. Gut microbiota as a candidate for lifespan extension: an ecological/evolutionary perspective targeted on living organisms as metaorganisms
    Ottaviani, E., Ventura, N., Mandrioli, M., Candela, M., Franchini, A., Franceschi, C. · 2011 · Biogerontology
91. Whole Genome Sequences of a Male and Female Supercentenarian, Ages Greater than 114 Years
    Paola Sebastiani, Alberto Riva, Monty A Montano, Phillip Pham, Ali Torkamani, Eugene Scherba, Gary Benson, Jacqueline N. Milton, Clinton T. Baldwin, Stacy L. Andersen et al. · 2012 · Frontiers in Genetics
92. Increased uncoupling protein (UCP) activity in Drosophila insulin-producing neurons attenuates insulin signaling and extends lifespan
    Fridell, Yih-Woei C., Hoh, Melissa, Kréneisz, Orsolya, Hosier, Suzanne, Chang, Chengyi, Scantling, Dane, Mulkey, Daniel K., Helfand, Stephen L. · 2009 · Aging
93. Aging of the Genome
    Vijg, Jan · 2007
94. Nuclear envelope alterations generate an aging-like epigenetic pattern in mice deficient in Zmpste24 metalloprotease
    Osorio, Fernando G., Varela, Ignacio, Lara, Ester, Puente, Xose S., Espada, Jesús, Santoro, Raffaella, Freije, José M. P., Fraga, Mario F., López‐Otín, Carlos · 2010 · Aging Cell
95. Rapamycin-Induced Glucose Intolerance: Hunger or Starvation Diabetes
    Blagosklonny, Mikhail V · 2011 · Cell Cycle
96. Age-related gene-specific changes of A-to-I mRNA editing in the human brain
    Nicholas, A., de Magalhaes, J.P., Kraytsberg, Y., Richfield, E.K., Levanon, E.Y., Khrapko, K. · 2010 · Mechanisms of Ageing and Development
97. Endocrine regulation of heat shock protein mRNA levels in long-lived dwarf mice
    Swindell, William R., Masternak, Michal M., Kopchick, John J., Conover, Cheryl A., Bartke, Andrzej, Miller, Richard A. · 2009 · Mechanisms of Ageing and Development
98. Reprogramming aging and progeria
    Freije, José MP, López-Otín, Carlos · 2012 · Current Opinion in Cell Biology
99. Meta-analysis of gene expression in the mouse liver reveals biomarkers associated with inflammation increased early during aging
    Lee, Janice S., Ward, William O., Ren, Hongzu, Vallanat, Beena, Darlington, Gretchen J., Han, Eun-Soo, Laguna, Juan C., DeFord, James H., Papaconstantinou, John, Selman, Colin et al. · 2012 · Mechanisms of Ageing and Development
100. Alternate-day fasting reverses the age-associated hypertrophy phenotype in rat heart by influencing the ERK and PI3K signaling pathways
     Castello, Laura, Maina, Marco, Testa, Gabriella, Cavallini, Gabriella, Biasi, Fiorella, Donati, Alessio, Leonarduzzi, Gabriella, Bergamini, Ettore, Poli, Giuseppe, Chiarpotto, Elena · 2011 · Mechanisms of Ageing and Development
101. Micromanaging aging with miRNAs: new messages from the nuclear envelope
     Ugalde, Alejandro P., Español, Yaiza, López-Otín, Carlos · 2011 · Nucleus
102. Genes Against Aging
     Richard A. Miller · 2012 · The Journals of Gerontology Series A
103. Mouse models to decipher the PI3K signaling network in human cancer
     Renner, Oliver, Carnero, Amancio · 2009 · Current Molecular Medicine