Cited by 2,016Neurogenesis and neuroplasticity mechanismsDevelopmental Biology and Gene RegulationNeuroscience and Neuropharmacology Research

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Neurons derived from radial glial cells establish radial units in neocortex

Noctor, Stephen C., Flint, Alexander C., Weissman, Tamily A., Dammerman, Ryan S., Kriegstein, Arnold R.·2001·Nature

DOI 10.1038/35055553

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Abstract

The neocortex of the adult brain consists of neurons and glia that are generated by precursor cells of the embryonic ventricular zone. In general, glia are generated after neurons during development, but radial glia are an exception to this rule. Radial glia are generated before neurogenesis and guide neuronal migration. Radial glia are mitotically active throughout neurogenesis, and disappear or become astrocytes when neuronal migration is complete. Although the lineage relationships of cortical neurons and glia have been explored, the clonal relationship of radial glia to other cortical cells remains unknown. It has been suggested that radial glia may be neuronal precursors, but this has not been demonstrated in vivo. We have used a retroviral vector encoding enhanced green fluorescent protein to label precursor cells in vivo and have examined clones 1-3 days later using morphological, immunohistochemical and electrophysiological techniques. Here we show that clones consist of mitotic radial glia and postmitotic neurons, and that neurons migrate along clonally related radial glia. Time-lapse images show that proliferative radial glia generate neurons. Our results support the concept that a lineage relationship between neurons and proliferative radial glia may underlie the radial organization of neocortex.

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Specification of Cerebral Cortical Areas
Rakic, P. (1988) · Science · doi:10.1126/science.3291116 · Cited by 3,127
The columnar organization of the neocortex
Mountcastle, V. B. (1997) · Brain · doi:10.1093/brain/120.4.701 · Cited by 2,314
Mode of cell migration to the superficial layers of fetal monkey neocortex
Rakic, P. (1972) · Journal of Comparative Neurology · doi:10.1002/cne.901450105 · Cited by 2,170
Neurogenesis in the Dentate Gyrus of the Adult Tree Shrew Is Regulated by Psychosocial Stress and NMDA Receptor Activation
Gould, E., McEwen, B. S., Tanapat, P., Galea, L. A. M., & Fuchs, E. (1997) · The Journal of Neuroscience · doi:10.1523/jneurosci.17-07-02492.1997 · Cited by 1,496
Interneuron Migration from Basal Forebrain to Neocortex: Dependence on Dlx Genes
Anderson, S. A., Eisenstat, D. D., Shi, L., & Rubenstein, J. L. R. (1997) · Science · doi:10.1126/science.278.5337.474 · Cited by 1,462
Isolation of radial glial cells by fluorescent-activated cell sorting reveals a neuronal lineage
Malatesta, P., Hartfuss, E., & Götz, M. (2000) · Development · doi:10.1242/dev.127.24.5253 · Cited by 1,157
Whole cell recording from neurons in slices of reptilian and mammalian cerebral cortex
Blanton, M. G., Turco, J. J. L., & Kriegstein, A. R. (1989) · Journal of Neuroscience Methods · doi:10.1016/0165-0270(89)90131-3 · Cited by 945
Self-citation
Identification of major cell classes in the developing mammalian nervous system
Hockfield, S. J., & McKay, R. D. G. (1985) · Journal of Neuroscience · doi:10.1523/jneurosci.05-12-03310.1985 · Cited by 792
Radial Glial Identity Is Promoted by Notch1 Signaling in the Murine Forebrain
Gaiano, N., Nye, J. S., & Fishell, G. (2000) · Neuron · doi:10.1016/s0896-6273(00)81172-1 · Cited by 727
Embryonic vertebrate central nervous system: Revised terminology
Angevine, J. B., Bodian, D., Coulombre, A. J., Edds, M. V., Hamburger, V., Jacobson, M., Lyser, K. M., Prestige, M. C., Sidman, R. L., Varon, S. S., et al. (1970) · The Anatomical Record · doi:10.1002/ar.1091660214 · Cited by 727

Show all 30 references

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Self-citation
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Stiles, J., & Jernigan, T. L. (2010) · Neuropsychology Review · doi:10.1007/s11065-010-9148-4 · Cited by 2,009
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Rakic, P. (2009) · Nature reviews. Neuroscience · doi:10.1038/nrn2719 · Cited by 1,565
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Song, H., Stevens, C. F., & Gage, F. H. (2002) · Nature · doi:10.1038/417039a · Cited by 1,452
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Development and Evolution of the Human Neocortex
Lui, J. H., Hansen, D. V., & Kriegstein, A. R. (2011) · Cell · doi:10.1016/j.cell.2011.06.030 · Cited by 1,342
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Englund, C., Fink, A., Lau, C., Pham, D., Daza, R. A. M., Bulfone, A., Kowalczyk, T., & Hevner, R. F. (2005) · The Journal of Neuroscience · doi:10.1523/jneurosci.2899-04.2005 · Cited by 1,261
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Kempermann, G., Song, H., & Gage, F. H. (2015) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a018812 · Cited by 1,072
Microglia Regulate the Number of Neural Precursor Cells in the Developing Cerebral Cortex
Cunningham, C. L., Martínez-Cerdeño, V., & Noctor, S. C. (2013) · The Journal of Neuroscience · doi:10.1523/jneurosci.3441-12.2013 · Cited by 976
Self-citation
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Mirzadeh, Z., Merkle, F. T., Soriano-Navarro, M., Garcia-Verdugo, J. M., & Alvarez-Buylla, A. (2008) · Cell stem cell · doi:10.1016/j.stem.2008.07.004 · Cited by 1,015
Origin of oligodendrocytes in the subventricular zone of the adult brain
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Self-citation
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RODRIGUEZ, E., BLAZQUEZ, J., PASTOR, F., PELAEZ, B., PENA, P., PERUZZO, B., & AMAT, P. (2005) · International review of cytology · doi:10.1016/s0074-7696(05)47003-5 · Cited by 475
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Ooto, S., Akagi, T., Kageyama, R., Akita, J., Mandai, M., Honda, Y., & Takahashi, M. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0402129101 · Cited by 454
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Fausett, B. V., & Goldman, D. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.0332-06.2006 · Cited by 435
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Cadwell, C. R., Bhaduri, A., Mostajo-Radji, M. A., Keefe, M. G., & Nowakowski, T. J. (2019) · Neuron · doi:10.1016/j.neuron.2019.07.009 · Cited by 408
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Mori, T., Tanaka, K., Buffo, A., Wurst, W., Kühn, R., & Götz, M. (2006) · Glia · doi:10.1002/glia.20350 · Cited by 398
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Marin, O., Valiente, M., Ge, X., & Tsai, L.-H. (2010) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a001834 · Cited by 417
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Lodato, S., & Arlotta, P. (2015) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev-cellbio-100814-125353 · Cited by 389
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Kolk, S. M., & Rakic, P. (2022) · Neuropsychopharmacology · doi:10.1038/s41386-021-01137-9 · Cited by 378
“Through close interplay between cell-autonomous events and local as well as external cues, neurons generated close to the ventricle start migrating in radial columns [45, 46, 50, 51].”
Background
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Leone, D. P., Srinivasan, K., Chen, B., Alcamo, E., & McConnell, S. K. (2008) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2008.05.006 · Cited by 382
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Lukaszewicz, A., Savatier, P., Cortay, V., Giroud, P., Huissoud, C., Berland, M., Kennedy, H., & Dehay, C. (2005) · Neuron · doi:10.1016/j.neuron.2005.06.032 · Cited by 315
Oligodendrocyte development and the onset of myelination in the human fetal brain
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Self-citation
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Preferential electrical coupling regulates neocortical lineage-dependent microcircuit assembly
Yu, Y.-C., He, S., Chen, S., Fu, Y., Brown, K. N., Yao, X.-H., Ma, J., Gao, K. P., Sosinsky, G. E., Huang, K., et al. (2012) · Nature · doi:10.1038/nature10958 · Cited by 219
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Cell transplantation therapies for spinal cord injury focusing on induced pluripotent stem cells
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Self-citation
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Wu, S.-X., Goebbels, S., Nakamura, K., Nakamura, K., Kometani, K., Minato, N., Kaneko, T., Nave, K.-A., & Tamamaki, N. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0508560102 · Cited by 198
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Emerging roles of neural stem cells in cerebral cortex development and evolution
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González, M., Cabrera‐Socorro, A., Pérez‐García, C. G., Fraser, J. D., López, F. J., Alonso, R., & Meyer, G. (2007) · Journal of Comparative Neurology · doi:10.1002/cne.21419 · Cited by 167
Regulation of Protein Tyrosine Kinase Signaling by Substrate Degradation during Brain Development
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Martini, F. J., Valiente, M., López Bendito, G., Szabó, G., Moya, F., Valdeolmillos, M., & Marín, O. (2009) · Development · doi:10.1242/dev.025502 · Cited by 147
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Lineage-specific laminar organization of cortical GABAergic interneurons
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Authors: Noctor, S. C., Flint, A. C., Weissman, T. A., Dammerman, R. S., & Kriegstein, A. R.
Affiliations: Columbia University Irving Medical Center (US)
Columbia University (US)
Corresponding author: Kriegstein, Arnold R.
ORCID: Noctor, Stephen C.
Flint, Alexander C.
Weissman, Tamily A.
Kriegstein, Arnold R.
Venue: Nature
Publisher: Springer Science and Business Media LLC
Published: 2001-02
Volume: 409
Issue: 6821
Pages: 714-720
ISSN: 0028-0836 (ISSN-L)
1476-4687
DOI: 10.1038/35055553
OpenAlex: W1503727145
Cited by: 2,016
References: 30
Citations by year: 2026: 41 · 2025: 44 · 2024: 42 · 2023: 64 · 2022: 56 · 2021: 68 · 2020: 108 · 2019: 89 · 2018: 57 · 2017: 75 · 2016: 71 · 2015: 91 · 2014: 90 · 2013: 98 · 2012: 103
FWCI: 21.58
Type: journal article
Language: en
Open access: closed
Licence: www.springer.com/tdm (tdm)
Locations: Nature (publishedVersion)
PubMed (publishedVersion)
RePEc: Research Papers in Economics (submittedVersion)
Topics: Life Sciences › Neuroscience › Developmental Neuroscience › Neurogenesis and neuroplasticity mechanisms
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Developmental Biology and Gene Regulation
Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
Keywords: radial glia, neocortex, neuronal migration, neuronal lineage, clonal analysis, neurogenesis, retroviral labeling, time-lapse imaging
MeSH terms: Animals, Antigens, Differentiation, Cell Differentiation, Cell Movement, Clone Cells, Luminescent Proteins, Mitosis, Neuroglia, Neurons, Rats, Sprague-Dawley, Microscopy, Video, Neocortex, Green Fluorescent Proteins, Rats

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Neurons derived from radial glial cells establish radial units in neocortex

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