Intestinal microbiota metabolism of l-carnitine, a nutrient in red meat, promotes atherosclerosis

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1. Carnitine metabolism to trimethylamine by an unusual Rieske-type oxygenase from human microbiota
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2. The gut microbial metabolite trimethylamine N-oxide aggravates GVHD by inducing M1 macrophage polarization in mice
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3. Trimethylamine and Trimethylamine N-Oxide, a Flavin-Containing Monooxygenase 3 (FMO3)-Mediated Host-Microbiome Metabolic Axis Implicated in Health and Disease
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4. Small metabolites, possible big changes: A microbiota-centered view of non-alcoholic fatty liver disease
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6. Structural variation in the gut microbiome associates with host health
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7. Serum Trimethylamine-N-Oxide Is Strongly Related to Renal Function and Predicts Outcome in Chronic Kidney Disease
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8. Intestinal Microbiota-Dependent Phosphatidylcholine Metabolites, Diastolic Dysfunction, and Adverse Clinical Outcomes in Chronic Systolic Heart Failure
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9. Flavin containing monooxygenase 3 exerts broad effects on glucose and lipid metabolism and atherosclerosis
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10. Measurement of trimethylamine-N-oxide by stable isotope dilution liquid chromatography tandem mass spectrometry
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11. l-Carnitine in omnivorous diets induces an atherogenic gut microbial pathway in humans
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12. Association of Dietary Patterns With Risk of Colorectal Cancer Subtypes Classified by <i>Fusobacterium nucleatum</i> in Tumor Tissue
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13. HMGB1: A Common Biomarker and Potential Target for TBI, Neuroinflammation, Epilepsy, and Cognitive Dysfunction
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14. Gut reactions: Breaking down xenobiotic–microbiome interactions
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15. Analysis of Gut Microbiota in Coronary Artery Disease Patients: a Possible Link between Gut Microbiota and Coronary Artery Disease
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16. Seasonal Variation in Human Gut Microbiome Composition
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17. Host Genetics and Gut Microbiome: Challenges and Perspectives
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18. Transforming berberine into its intestine-absorbable form by the gut microbiota
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19. Influences of diet and the gut microbiome on epigenetic modulation in cancer and other diseases
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20. Trimethylamine‐<i>N</i>‐oxide promotes brain aging and cognitive impairment in mice
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21. Microbiota Depletion Impairs Thermogenesis of Brown Adipose Tissue and Browning of White Adipose Tissue
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22. Trimethylamine-N-Oxide Instigates NLRP3 Inflammasome Activation and Endothelial Dysfunction
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23. The gut–kidney axis
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24. Trimethylamine N-oxide promotes atherosclerosis via CD36-dependent MAPK/JNK pathway
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25. Prediabetes and Cardiovascular Disease
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26. Trimethylamine-N-Oxide Promotes Vascular Calcification Through Activation of NLRP3 (Nucleotide-Binding Domain, Leucine-Rich-Containing Family, Pyrin Domain-Containing-3) Inflammasome and NF-κB (Nuclear Factor κB) Signals
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27. The TMAO-Producing Enzyme Flavin-Containing Monooxygenase 3 Regulates Obesity and the Beiging of White Adipose Tissue
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28. Food, immunity, and the microbiome
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29. Microbiota succession throughout life from the cradle to the grave
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30. Plant Protein and Animal Proteins: Do They Differentially Affect Cardiovascular Disease Risk?
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31. Gut Microbe-Generated Trimethylamine <i>N</i> -Oxide From Dietary Choline Is Prothrombotic in Subjects
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32. Trimethylamine N-oxide in atherogenesis: impairing endothelial self-repair capacity and enhancing monocyte adhesion
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33. Host-microbial interactions in the metabolism of therapeutic and diet-derived xenobiotics
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34. Microbial impact on cholesterol and bile acid metabolism: current status and future prospects
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35. Plasma Choline Metabolites and Colorectal Cancer Risk in the Women's Health Initiative Observational Study
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36. Linking the Microbiota, Chronic Disease, and the Immune System
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37. Trimethylamine-N-oxide (TMAO)-induced atherosclerosis is associated with bile acid metabolism
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38. Evolution, human-microbe interactions, and life history plasticity
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40. Microbiota-mediated inflammation and antimicrobial defense in the intestine
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41. Effect of egg ingestion on trimethylamine-N-oxide production in humans: a randomized, controlled, dose-response study , , ,
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43. Characterization and Detection of a Widely Distributed Gene Cluster That Predicts Anaerobic Choline Utilization by Human Gut Bacteria
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44. Fecal microbiota transplantation broadening its application beyond intestinal disorders
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45. A Prospective Metagenomic and Metabolomic Analysis of the Impact of Exercise and/or Whey Protein Supplementation on the Gut Microbiome of Sedentary Adults
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47. Betaine and Trimethylamine-N-Oxide as Predictors of Cardiovascular Outcomes Show Different Patterns in Diabetes Mellitus: An Observational Study
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49. Non-caloric artificial sweeteners and the microbiome: findings and challenges
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50. The promise of the gut microbiome as part of individualized treatment strategies
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51. Plasma levels of trimethylamine-N-oxide are confounded by impaired kidney function and poor metabolic control
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52. Elevated Circulating Trimethylamine N-Oxide Levels Contribute to Endothelial Dysfunction in Aged Rats through Vascular Inflammation and Oxidative Stress
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53. Association of changes in red meat consumption with total and cause specific mortality among US women and men: two prospective cohort studies
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54. Microbial-derived metabolites as a risk factor of age-related cognitive decline and dementia
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55. Gut microbiota, diet, and obesity-related disorders: the good, the bad, and the future challenges
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56. Trimethylamine-N-Oxide: A Carnitine-Derived Metabolite That Prolongs the Hypertensive Effect of Angiotensin II in Rats
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57. Diet drives quick changes in the metabolic activity and composition of human gut microbiota in a validated in vitro gut model
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58. A genome-wide systems analysis reveals strong link between colorectal cancer and trimethylamine N-oxide (TMAO), a gut microbial metabolite of dietary meat and fat
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59. Red meat intake and risk of coronary heart disease among US men: prospective cohort study
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60. Microbial Enterotypes, Inferred by the Prevotella-to-Bacteroides Ratio, Remained Stable during a 6-Month Randomized Controlled Diet Intervention with the New Nordic Diet
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61. Deciphering the Chemical Lexicon of Host–Gut Microbiota Interactions
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62. Plasma Concentrations of Trimethylamine-N-oxide Are Directly Associated with Dairy Food Consumption and Low-Grade Inflammation in a German Adult Population
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63. Involvement of a Non-Human Sialic Acid in Human Cancer
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64. Gut Microbial Associations to Plasma Metabolites Linked to Cardiovascular Phenotypes and Risk: A Cross-Sectional Study
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65. The cross talk between microbiota and the immune system: metabolites take center stage
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66. Gut microbiome and kidney disease: a bidirectional relationship
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67. Microbial Transplantation With Human Gut Commensals Containing CutC Is Sufficient to Transmit Enhanced Platelet Reactivity and Thrombosis Potential
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68. L-Carnitine intake and high trimethylamine N-oxide plasma levels correlate with low aortic lesions in ApoE−/− transgenic mice expressing CETP
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69. Enterosalivary nitrate metabolism and the microbiome: Intersection of microbial metabolism, nitric oxide and diet in cardiac and pulmonary vascular health
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70. Suppression of the gut microbiome ameliorates age‐related arterial dysfunction and oxidative stress in mice
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71. A review of potential metabolic etiologies of the observed association between red meat consumption and development of type 2 diabetes mellitus
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72. The influence of the human microbiome and probiotics on cardiovascular health
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73. Metabolomic analysis of prostate cancer risk in a prospective cohort: The alpha‐tocopherol, beta‐carotene cancer prevention (ATBC) study
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74. Gut microbiota metabolites, amino acid metabolites and improvements in insulin sensitivity and glucose metabolism: the POUNDS Lost trial
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75. Advanced chronic kidney disease populations have elevated trimethylamine N-oxide levels associated with increased cardiovascular events
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76. Faecal bacterial and short-chain fatty acids signature in hypercholesterolemia
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77. Gut Microbiota and Ischemic Stroke: The Role of Trimethylamine N-Oxide
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78. Trimethylamine N‐oxide: breathe new life
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79. Characterization of gut microbiota profiles in coronary artery disease patients using data mining analysis of terminal restriction fragment length polymorphism: gut microbiota could be a diagnostic marker of coronary artery disease
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80. Trimethylamine <i>N</i> ‐Oxide and Mortality Risk in Patients With Peripheral Artery Disease
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84. Flavin monooxygenase 3, the host hepatic enzyme in the metaorganismal trimethylamine N‐oxide‐generating pathway, modulates platelet responsiveness and thrombosis risk
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94. TMAO is Associated with Mortality: Impact of Modestly Impaired Renal Function
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95. Gut microbial metabolite TMAO contributes to renal dysfunction in a mouse model of diet-induced obesity
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