Overcoming barriers in photodynamic therapy harnessing nano-formulation strategies

Electric Field Effect in Atomically Thin Carbon Films

Novoselov, K. S., Geim, A. K., Morozov, S. V., Jiang, D., Zhang, Y., Dubonos, S. V., Grigorieva, I. V., & Firsov, A. A. (2004) · Science · doi:10.1126/science.1102896 · Cited by 66,834

Electrochemical Photolysis of Water at a Semiconductor Electrode

FUJISHIMA, A., & HONDA, K. (1972) · Nature · doi:10.1038/238037a0 · Cited by 34,169

C60: Buckminsterfullerene

Kroto, H. W., Heath, J. R., O’Brien, S. C., Curl, R. F., & Smalley, R. E. (1985) · Nature · doi:10.1038/318162a0 · Cited by 16,083

Free radicals and antioxidants in normal physiological functions and human disease

Valko, M., Leibfritz, D., Moncol, J., Cronin, M. T. D., Mazur, M., & Telser, J. (2007) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2006.07.001 · Cited by 14,269

Apoptosis: A Review of Programmed Cell Death

Elmore, S. (2007) · Toxicologic Pathology · doi:10.1080/01926230701320337 · Cited by 13,853

Two‐Dimensional Nanocrystals Produced by Exfoliation of Ti3AlC2

Naguib, M., Kurtoglu, M., Presser, V., Lu, J., Niu, J., Heon, M., Hultman, L., Gogotsi, Y., & Barsoum, M. W. (2011) · Advanced Materials · doi:10.1002/adma.201102306 · Cited by 11,855

Angiogenesis in cancer and other diseases

Carmeliet, P., & Jain, R. K. (2000) · Nature · doi:10.1038/35025220 · Cited by 9,070

Mitochondria and Apoptosis

Green, D. R., & Reed, J. C. (1998) · Science · doi:10.1126/science.281.5381.1309 · Cited by 8,965

Nanocarriers as an emerging platform for cancer therapy

Peer, D., Karp, J. M., Hong, S., Farokhzad, O. C., Margalit, R., & Langer, R. (2007) · Nature Nanotechnology · doi:10.1038/nnano.2007.387 · Cited by 8,710

Two-Dimensional Nanosheets Produced by Liquid Exfoliation of Layered Materials

Coleman, J. N., Lotya, M., O’Neill, A., Bergin, S. D., King, P. J., Khan, U., Young, K., Gaucher, A., De, S., Smith, R. J., et al. (2011) · Science · doi:10.1126/science.1194975 · Cited by 7,242

Autophagy in the Pathogenesis of Disease

Levine, B., & Kroemer, G. (2008) · Cell · doi:10.1016/j.cell.2007.12.018 · Cited by 7,069

Free radicals, metals and antioxidants in oxidative stress-induced cancer

Valko, M., Rhodes, C. J., Moncol, J., Izakovic, M., & Mazur, M. (2006) · Chemico-Biological Interactions · doi:10.1016/j.cbi.2005.12.009 · Cited by 6,680

Autophagy fights disease through cellular self-digestion

Mizushima, N., Levine, B., Cuervo, A. M., & Klionsky, D. J. (2008) · Nature · doi:10.1038/nature06639 · Cited by 6,452

The biochemistry of apoptosis

Hengartner, M. O. (2000) · Nature · doi:10.1038/35037710 · Cited by 5,779

Cancer Cell Imaging and Photothermal Therapy in the Near-Infrared Region by Using Gold Nanorods

Huang, X., El-Sayed, I. H., Qian, W., & El-Sayed, M. A. (2006) · Journal of the American Chemical Society · doi:10.1021/ja057254a · Cited by 5,436

Elements of cancer immunity and the cancer–immune set point

Chen, D. S., & Mellman, I. (2017) · Nature · doi:10.1038/nature21349 · Cited by 5,352

Recent Advances in Ultrathin Two-Dimensional Nanomaterials

Tan, C., Cao, X., Wu, X.-J., He, Q., Yang, J., Zhang, X., Chen, J., Zhao, W., Han, S., Nam, G.-H., et al. (2017) · Chemical Reviews · doi:10.1021/acs.chemrev.6b00558 · Cited by 5,100

The future of immune checkpoint therapy

Sharma, P., & Allison, J. P. (2015) · Science · doi:10.1126/science.aaa8172 · Cited by 4,878

Reactive oxygen species (ROS) homeostasis and redox regulation in cellular signaling

Ray, P. D., Huang, B.-W., & Tsuji, Y. (2012) · Cellular Signalling · doi:10.1016/j.cellsig.2012.01.008 · Cited by 4,373

Noble Metals on the Nanoscale: Optical and Photothermal Properties and Some Applications in Imaging, Sensing, Biology, and Medicine

Jain, P. K., Huang, X., El-Sayed, I. H., & El-Sayed, M. A. (2008) · Accounts of Chemical Research · doi:10.1021/ar7002804 · Cited by 4,215

Innate and adaptive immune cells in the tumor microenvironment

Gajewski, T. F., Schreiber, H., & Fu, Y.-X. (2013) · Nature Immunology · doi:10.1038/ni.2703 · Cited by 4,148

Nanoshell-mediated near-infrared thermal therapy of tumors under magnetic resonance guidance

Hirsch, L. R., Stafford, R. J., Bankson, J. A., Sershen, S. R., Rivera, B., Price, R. E., Hazle, J. D., Halas, N. J., & West, J. L. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2232479100 · Cited by 3,955

Liquid Exfoliation of Layered Materials

Nicolosi, V., Chhowalla, M., Kanatzidis, M. G., Strano, M. S., & Coleman, J. N. (2013) · Science · doi:10.1126/science.1226419 · Cited by 3,796

Development by Self-Digestion

Levine, B., & Klionsky, D. J. (2004) · Developmental Cell · doi:10.1016/s1534-5807(04)00099-1 · Cited by 3,678

Modulation of oxidative stress as an anticancer strategy

Gorrini, C., Harris, I. S., & Mak, T. W. (2013) · Nature Reviews Drug Discovery · doi:10.1038/nrd4002 · Cited by 3,579

Self-eating and self-killing: crosstalk between autophagy and apoptosis

Maiuri, M. C., Zalckvar, E., Kimchi, A., & Kroemer, G. (2007) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2239 · Cited by 3,577

The EPR effect: Unique features of tumor blood vessels for drug delivery, factors involved, and limitations and augmentation of the effect

Fang, J., Nakamura, H., & Maeda, H. (2011) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2010.04.009 · Cited by 3,559

Recent advances in the chemistry of lanthanide-doped upconversion nanocrystals

Wang, F., & Liu, X. (2009) · Chemical Society Reviews · doi:10.1039/b809132n · Cited by 3,004

Nanoparticles in Photodynamic Therapy

Lucky, S. S., Soo, K. C., & Zhang, Y. (2015) · Chemical Reviews · doi:10.1021/cr5004198 · Cited by 2,980

Second window for in vivo imaging

Smith, A. M., Mancini, M. C., & Nie, S. (2009) · Nature Nanotechnology · doi:10.1038/nnano.2009.326 · Cited by 2,848

Upconversion Nanoparticles: Design, Nanochemistry, and Applications in Theranostics

Chen, G., Qiu, H., Prasad, P. N., & Chen, X. (2014) · Chemical Reviews · doi:10.1021/cr400425h · Cited by 2,699

Gold nanoparticles in delivery applications☆

GHOSH, P., HAN, G., DE, M., KIM, C., & ROTELLO, V (2008) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2008.03.016 · Cited by 2,694

Photodynamic therapy and anti-tumour immunity

Castano, A. P., Mroz, P., & Hamblin, M. R. (2006) · Nature Reviews Cancer · doi:10.1038/nrc1894 · Cited by 2,676

Atomic‐Layer Graphene as a Saturable Absorber for Ultrafast Pulsed Lasers

Bao, Q., Zhang, H., Wang, Y., Ni, Z., Yan, Y., Shen, Z. X., Loh, K. P., & Tang, D. Y. (2009) · Advanced Functional Materials · doi:10.1002/adfm.200901007 · Cited by 2,612

The molecular machinery of regulated cell death

Tang, D., Kang, R., Berghe, T. V., Vandenabeele, P., & Kroemer, G. (2019) · Cell Research · doi:10.1038/s41422-019-0164-5 · Cited by 2,549

Upconverting Nanoparticles

Haase, M., & Schäfer, H. (2011) · Angewandte Chemie International Edition · doi:10.1002/anie.201005159 · Cited by 2,503

Upconversion Luminescent Materials: Advances and Applications

Zhou, J., Liu, Q., Feng, W., Sun, Y., & Li, F. (2015) · Chemical Reviews · doi:10.1021/cr400478f · Cited by 2,254

Synthesis of MoS 2 and MoSe 2 Films with Vertically Aligned Layers

Kong, D., Wang, H., Cha, J. J., Pasta, M., Koski, K. J., Yao, J., & Cui, Y. (2013) · Nano Letters · doi:10.1021/nl400258t · Cited by 2,250

Apoptosis, Pyroptosis, and Necrosis: Mechanistic Description of Dead and Dying Eukaryotic Cells

Fink, S. L., & Cookson, B. T. (2005) · Infection and Immunity · doi:10.1128/iai.73.4.1907-1916.2005 · Cited by 2,205

Power dependence of upconversion luminescence in lanthanide and transition-metal-ion systems

Pollnau, M., Gamelin, D. R., Lüthi, S. R., Güdel, H. U., & Hehlen, M. P. (2000) · Physical Review B · doi:10.1103/physrevb.61.3337 · Cited by 2,197

BODIPY dyes in photodynamic therapy

Kamkaew, A., Lim, S. H., Lee, H. B., Kiew, L. V., Chung, L. Y., & Burgess, K. (2013) · Chem. Soc. Rev. · doi:10.1039/c2cs35216h · Cited by 2,104

Two‐Photon Absorption and the Design of Two‐Photon Dyes

Pawlicki, M., Collins, H. A., Denning, R. G., & Anderson, H. L. (2009) · Angewandte Chemie International Edition · doi:10.1002/anie.200805257 · Cited by 2,019

Tumor Angiogenesis

Kerbel, R. S. (2008) · New England Journal of Medicine · doi:10.1056/nejmra0706596 · Cited by 1,948

Crosstalk between cancer and immune cells: role of STAT3 in the tumour microenvironment

Yu, H., Kortylewski, M., & Pardoll, D. (2007) · Nature Reviews Immunology · doi:10.1038/nri1995 · Cited by 1,804

VEGF as a Key Mediator of Angiogenesis in Cancer

Carmeliet, P. (2005) · Oncology · doi:10.1159/000088478 · Cited by 1,768

Large‐Area Vapor‐Phase Growth and Characterization of MoS2 Atomic Layers on a SiO2 Substrate

Zhan, Y., Liu, Z., Najmaei, S., Ajayan, P. M., & Lou, J. (2012) · Small · doi:10.1002/smll.201102654 · Cited by 1,741

Regulated necrosis: the expanding network of non-apoptotic cell death pathways

Berghe, T. V., Linkermann, A., Jouan-Lanhouet, S., Walczak, H., & Vandenabeele, P. (2014) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm3737 · Cited by 1,735

Biomedical Applications of Graphene and Graphene Oxide

Chung, C., Kim, Y.-K., Shin, D., Ryoo, S.-R., Hong, B. H., & Min, D.-H. (2013) · Accounts of Chemical Research · doi:10.1021/ar300159f · Cited by 1,696

Biocompatibility of Gold Nanoparticles and Their Endocytotic Fate Inside the Cellular Compartment: A Microscopic Overview

Shukla, R., Bansal, V., Chaudhary, M., Basu, A., Bhonde, R. R., & Sastry, M. (2005) · Langmuir · doi:10.1021/la0513712 · Cited by 1,687

Overcoming the Achilles' heel of photodynamic therapy

Fan, W., Huang, P., & Chen, X. (2016) · Chemical Society Reviews · doi:10.1039/c6cs00616g · Cited by 1,684

Nano-graphene in biomedicine: theranostic applications

Yang, K., Feng, L., Shi, X., & Liu, Z. (2013) · Chem. Soc. Rev. · doi:10.1039/c2cs35342c · Cited by 1,634

The role of apoptosis in response to photodynamic therapy: what, where, why, and how

Oleinick, N. L., Morris, R. L., & Belichenko, I. (2002) · Photochemical & Photobiological Sciences · doi:10.1039/b108586g · Cited by 1,503

In vivo photodynamic therapy using upconversion nanoparticles as remote-controlled nanotransducers

Idris, N. M., Gnanasammandhan, M. K., Zhang, J., Ho, P. C., Mahendran, R., & Zhang, Y. (2012) · Nature Medicine · doi:10.1038/nm.2933 · Cited by 1,464

Programmed cell death pathways in cancer: a review of apoptosis, autophagy and programmed necrosis

Ouyang, L., Shi, Z., Zhao, S., Wang, F. ‐., Zhou, T. ‐., Liu, B., & Bao, J. ‐. (2012) · Cell Proliferation · doi:10.1111/j.1365-2184.2012.00845.x · Cited by 1,452

Immune surveillance of tumors

Swann, J. B., & Smyth, M. J. (2007) · Journal of Clinical Investigation · doi:10.1172/jci31405 · Cited by 1,447

The current state and future directions of RNAi-based therapeutics

Setten, R. L., Rossi, J. J., & Han, S.-P. (2019) · Nature Reviews Drug Discovery · doi:10.1038/s41573-019-0017-4 · Cited by 1,443

Upconversion nanoparticles in biological labeling, imaging, and therapy

Wang, F., Banerjee, D., Liu, Y., Chen, X., & Liu, X. (2010) · The Analyst · doi:10.1039/c0an00144a · Cited by 1,409

A graphene quantum dot photodynamic therapy agent with high singlet oxygen generation

Ge, J., Lan, M., Zhou, B., Liu, W., Guo, L., Wang, H., Jia, Q., Niu, G., Huang, X., Zhou, H., et al. (2014) · Nature Communications · doi:10.1038/ncomms5596 · Cited by 1,406

Crosstalk between apoptosis.; necrosis and autophagy

Nikoletopoulou, V., Markaki, M., Palikaras, K., & Tavernarakis, N. (2013) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2013.06.001 · Cited by 1,366

Role of Bcl-2 family proteins in a non-apoptotic programmed cell death dependent on autophagy genes

Shimizu, S., Kanaseki, T., Mizushima, N., Mizuta, T., Arakawa-Kobayashi, S., Thompson, C. B., & Tsujimoto, Y. (2004) · Nature Cell Biology · doi:10.1038/ncb1192 · Cited by 1,358

To exploit the tumor microenvironment: Since the EPR effect fails in the clinic, what is the future of nanomedicine?

Danhier, F. (2016) · Journal of Controlled Release · doi:10.1016/j.jconrel.2016.11.015 · Cited by 1,288

Synthesis of Few-Layer Hexagonal Boron Nitride Thin Film by Chemical Vapor Deposition

Shi, Y., Hamsen, C., Jia, X., Kim, K. K., Reina, A., Hofmann, M., Hsu, A., Zhang, K., Li, H., Juang, Z., et al. (2010) · Nano Letters · doi:10.1021/nl1023707 · Cited by 1,231

Regulation of an ATG7 - beclin 1 Program of Autophagic Cell Death by Caspase-8

Yu, L., Alva, A., Su, H., Dutt, P., Freundt, E., Welsh, S., Baehrecke, E. H., & Lenardo, M. J. (2004) · Science · doi:10.1126/science.1096645 · Cited by 1,220

Grapheneviasonication assisted liquid-phase exfoliation

Ciesielski, A., & Samorì, P. (2014) · Chem. Soc. Rev. · doi:10.1039/c3cs60217f · Cited by 1,207

Autophagy and chemotherapy resistance: a promising therapeutic target for cancer treatment

Sui, X., Chen, R., Wang, Z., Huang, Z., Kong, N., Zhang, M., Han, W., Lou, F., Yang, J., Zhang, Q., et al. (2013) · Cell Death & Disease · doi:10.1038/cddis.2013.350 · Cited by 1,204

Mesoporous silica nanoparticles in drug delivery and biomedical applications

Wang, Y., Zhao, Q., Han, N., Bai, L., Li, J., Liu, J., Che, E., Hu, L., Zhang, Q., Jiang, T., et al. (2015) · Nanomedicine: Nanotechnology, Biology and Medicine · doi:10.1016/j.nano.2014.09.014 · Cited by 1,192

Porphyrin and Nonporphyrin Photosensitizers in Oncology: Preclinical and Clinical Advances in Photodynamic Therapy

O’Connor, A. E., Gallagher, W. M., & Byrne, A. T. (2009) · Photochemistry and Photobiology · doi:10.1111/j.1751-1097.2009.00585.x · Cited by 1,191

Innovative Strategies for Hypoxic‐Tumor Photodynamic Therapy

Li, X., Kwon, N., Guo, T., Liu, Z., & Yoon, J. (2018) · Angewandte Chemie International Edition · doi:10.1002/anie.201805138 · Cited by 1,175

Gold nanorod assisted near-infrared plasmonic photothermal therapy (PPTT) of squamous cell carcinoma in mice

Dickerson, E. B., Dreaden, E. C., Huang, X., El-Sayed, I. H., Chu, H., Pushpanketh, S., McDonald, J. F., & El-Sayed, M. A. (2008) · Cancer Letters · doi:10.1016/j.canlet.2008.04.026 · Cited by 1,172

Gold Nanomaterials at Work in Biomedicine

Yang, X., Yang, M., Pang, B., Vara, M., & Xia, Y. (2015) · Chemical Reviews · doi:10.1021/acs.chemrev.5b00193 · Cited by 1,162

The Double-Edged Sword of Autophagy Modulation in Cancer

White, E., & DiPaola, R. S. (2009) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-07-5023 · Cited by 1,138

Broadband graphene polarizer

Bao, Q., Zhang, H., Wang, B., Ni, Z., Lim, C. H. Y. X., Wang, Y., Tang, D. Y., & Loh, K. P. (2011) · Nature Photonics · doi:10.1038/nphoton.2011.102 · Cited by 1,109

Nanodrug Delivery: Is the Enhanced Permeability and Retention Effect Sufficient for Curing Cancer?

Nakamura, Y., Mochida, A., Choyke, P. L., & Kobayashi, H. (2016) · Bioconjugate Chemistry · doi:10.1021/acs.bioconjchem.6b00437 · Cited by 1,101

Cell death by necrosis: towards a molecular definition

Golstein, P., & Kroemer, G. (2007) · Trends in Biochemical Sciences · doi:10.1016/j.tibs.2006.11.001 · Cited by 1,044

Ultrathin Black Phosphorus Nanosheets for Efficient Singlet Oxygen Generation

Wang, H., Yang, X., Shao, W., Chen, S., Xie, J., Zhang, X., Wang, J., & Xie, Y. (2015) · Journal of the American Chemical Society · doi:10.1021/jacs.5b06025 · Cited by 1,041

Black Phosphorus Nanosheet‐Based Drug Delivery System for Synergistic Photodynamic/Photothermal/Chemotherapy of Cancer

Chen, W., Ouyang, J., Liu, H., Chen, M., Zeng, K., Sheng, J., Liu, Z., Han, Y., Wang, L., Li, J., et al. (2017) · Advanced Materials · doi:10.1002/adma.201603864 · Cited by 1,027

From Black Phosphorus to Phosphorene: Basic Solvent Exfoliation, Evolution of Raman Scattering, and Applications to Ultrafast Photonics

Guo, Z., Zhang, H., Lu, S., Wang, Z., Tang, S., Shao, J., Sun, Z., Xie, H., Wang, H., Yu, X., et al. (2015) · Advanced Functional Materials · doi:10.1002/adfm.201502902 · Cited by 1,006

Biodegradable black phosphorus-based nanospheres for in vivo photothermal cancer therapy

Shao, J., Xie, H., Huang, H., Li, Z., Sun, Z., Xu, Y., Xiao, Q., Yu, X.-F., Zhao, Y., Zhang, H., et al. (2016) · Nature Communications · doi:10.1038/ncomms12967 · Cited by 1,006

Improving conventional enhanced permeability and retention (EPR) effects; what is the appropriate target?

Kobayashi, H., Watanabe, R., & Choyke, P. L. (2014) · Theranostics · doi:10.7150/thno.7193 · Cited by 996

Strong Two-Photon-Induced Fluorescence from Photostable, Biocompatible Nitrogen-Doped Graphene Quantum Dots for Cellular and Deep-Tissue Imaging

Liu, Q., Guo, B., Rao, Z., Zhang, B., & Gong, J. R. (2013) · Nano Letters · doi:10.1021/nl400368v · Cited by 958

In vitro and in vivo two-photon luminescence imaging of single gold nanorods

Wang, H., Huff, T. B., Zweifel, D. A., He, W., Low, P. S., Wei, A., & Cheng, J.-X. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0504892102 · Cited by 950

Perfluorocarbon nanoparticles enhance reactive oxygen levels and tumour growth inhibition in photodynamic therapy

Cheng, Y., Cheng, H., Jiang, C., Qiu, X., Wang, K., Huan, W., Yuan, A., Wu, J., & Hu, Y. (2015) · Nature Communications · doi:10.1038/ncomms9785 · Cited by 941

Two-Photon Luminescence Imaging of Cancer Cells Using Molecularly Targeted Gold Nanorods

Durr, N. J., Larson, T., Smith, D. K., Korgel, B. A., Sokolov, K., & Ben-Yakar, A. (2007) · Nano Letters · doi:10.1021/nl062962v · Cited by 897

Black Phosphorus Nanosheets as a Robust Delivery Platform for Cancer Theranostics

Tao, W., Zhu, X., Yu, X., Zeng, X., Xiao, Q., Zhang, X., Ji, X., Wang, X., Shi, J., Zhang, H., et al. (2017) · Advanced Materials · doi:10.1002/adma.201603276 · Cited by 883

Optimized Metal–Organic-Framework Nanospheres for Drug Delivery: Evaluation of Small-Molecule Encapsulation

Zhuang, J., Kuo, C.-H., Chou, L.-Y., Liu, D.-Y., Weerapana, E., & Tsung, C.-K. (2014) · ACS Nano · doi:10.1021/nn406590q · Cited by 873

Advances in In Vivo Bioluminescence Imaging of Gene Expression

Contag, C. H., & Bachmann, M. H. (2002) · Annual Review of Biomedical Engineering · doi:10.1146/annurev.bioeng.4.111901.093336 · Cited by 870

Near-infrared light induced in vivo photodynamic therapy of cancer based on upconversion nanoparticles

Wang, C., Tao, H., Cheng, L., & Liu, Z. (2011) · Biomaterials · doi:10.1016/j.biomaterials.2011.05.007 · Cited by 824

Universal mechanical exfoliation of large-area 2D crystals

Huang, Y., Pan, Y.-H., Yang, R., Bao, L.-H., Meng, L., Luo, H.-L., Cai, Y.-Q., Liu, G.-D., Zhao, W.-J., Zhou, Z., et al. (2020) · Nature Communications · doi:10.1038/s41467-020-16266-w · Cited by 816

Semiconductor Quantum Dots for Photodynamic Therapy

Samia, A. C. S., Chen, X., & Burda, C. (2003) · Journal of the American Chemical Society · doi:10.1021/ja0386905 · Cited by 813

The transferrin receptor and the targeted delivery of therapeutic agents against cancer

Daniels, T. R., Bernabeu, E., Rodríguez, J. A., Patel, S., Kozman, M., Chiappetta, D. A., Holler, E., Ljubimova, J. Y., Helguera, G., & Penichet, M. L. (2012) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2011.07.016 · Cited by 807

Autophagy as a target for anticancer therapy

Janku, F., McConkey, D. J., Hong, D. S., & Kurzrock, R. (2011) · Nature Reviews Clinical Oncology · doi:10.1038/nrclinonc.2011.71 · Cited by 803

Superoxide is the major reactive oxygen species regulating autophagy

Chen, Y., Azad, M. B., & Gibson, S. B. (2009) · Cell Death & Differentiation · doi:10.1038/cdd.2009.49 · Cited by 796

Mechanisms in photodynamic therapy: part two—cellular signaling, cell metabolism and modes of cell death

Castano, A. P., Demidova, T. N., & Hamblin, M. R. (2005) · Photodiagnosis and Photodynamic Therapy · doi:10.1016/s1572-1000(05)00030-x · Cited by 767

Carbon Nanoparticle-based Fluorescent Bioimaging Probes

Bhunia, S. K., Saha, A., Maity, A. R., Ray, S. C., & Jana, N. R. (2013) · Scientific Reports · doi:10.1038/srep01473 · Cited by 750

Principles for targeting RNA with drug-like small molecules

Warner, K. D., Hajdin, C. E., & Weeks, K. M. (2018) · Nature Reviews Drug Discovery · doi:10.1038/nrd.2018.93 · Cited by 749

Molecular effectors of multiple cell death pathways initiated by photodynamic therapy

Buytaert, E., Dewaele, M., & Agostinis, P. (2007) · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · doi:10.1016/j.bbcan.2007.07.001 · Cited by 746

Nanoscale Metal–Organic Framework for Highly Effective Photodynamic Therapy of Resistant Head and Neck Cancer

Lu, K., He, C., & Lin, W. (2014) · Journal of the American Chemical Society · doi:10.1021/ja508679h · Cited by 745

Dual role of hydrogen peroxide in cancer: Possible relevance to cancer chemoprevention and therapy

López-Lázaro, M. (2007) · Cancer Letters · doi:10.1016/j.canlet.2006.10.029 · Cited by 715

Self‐Assembled Peptide‐ and Protein‐Based Nanomaterials for Antitumor Photodynamic and Photothermal Therapy

Abbas, M., Zou, Q., Li, S., & Yan, X. (2017) · Advanced Materials · doi:10.1002/adma.201605021 · Cited by 711

Chemically Exfoliated MoS2 as Near‐Infrared Photothermal Agents

Chou, S. S., Kaehr, B., Kim, J., Foley, B. M., De, M., Hopkins, P. E., Huang, J., Brinker, C. J., & Dravid, V. P. (2013) · Angewandte Chemie International Edition · doi:10.1002/anie.201209229 · Cited by 692

Surface Modified Ti3C2 MXene Nanosheets for Tumor Targeting Photothermal/Photodynamic/Chemo Synergistic Therapy

Liu, G., Zou, J., Tang, Q., Yang, X., Zhang, Y., Zhang, Q., Huang, W., Chen, P., Shao, J., & Dong, X. (2017) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.7b13421 · Cited by 691

Extraordinary Photoluminescence and Strong Temperature/Angle-Dependent Raman Responses in Few-Layer Phosphorene

Zhang, S., Yang, J., Xu, R., Wang, F., Li, W., Ghufran, M., Zhang, Y.-W., Yu, Z., Zhang, G., Qin, Q., et al. (2014) · ACS Nano · doi:10.1021/nn503893j · Cited by 688

Anti-angiogenesis for cancer revisited: Is there a role for combinations with immunotherapy?

Ramjiawan, R. R., Griffioen, A. W., & Duda, D. G. (2017) · Angiogenesis · doi:10.1007/s10456-017-9552-y · Cited by 672

Prospects and Challenges of Graphene in Biomedical Applications

Bitounis, D., Ali‐Boucetta, H., Hong, B. H., Min, D., & Kostarelos, K. (2013) · Advanced Materials · doi:10.1002/adma.201203700 · Cited by 671

Autophagy and multidrug resistance in cancer

Li, Y.-J., Lei, Y.-H., Yao, N., Wang, C.-R., Hu, N., Ye, W.-C., Zhang, D.-M., & Chen, Z.-S. (2017) · Chinese Journal of Cancer · doi:10.1186/s40880-017-0219-2 · Cited by 665

Preparation of 2D material dispersions and their applications

Cai, X., Luo, Y., Liu, B., & Cheng, H.-M. (2018) · Chemical Society Reviews · doi:10.1039/c8cs00254a · Cited by 665

Wet-chemical synthesis and applications of non-layer structured two-dimensional nanomaterials

Tan, C., & Zhang, H. (2015) · Nature Communications · doi:10.1038/ncomms8873 · Cited by 651

Toxicity Assessments of Multisized Gold and Silver Nanoparticles in Zebrafish Embryos

Bar‐Ilan, O., Albrecht, R. M., Fako, V. E., & Furgeson, D. Y. (2009) · Small · doi:10.1002/smll.200801716 · Cited by 648

Ligand-Targeted Drug Delivery

Srinivasarao, M., & Low, P. S. (2017) · Chemical Reviews · doi:10.1021/acs.chemrev.7b00013 · Cited by 605

Photosensitized oxidation of membrane lipids: reaction pathways, cytotoxic effects, and cytoprotective mechanisms

Girotti, A. W. (2001) · Journal of Photochemistry and Photobiology B: Biology · doi:10.1016/s1011-1344(01)00207-x · Cited by 574

Photodynamic Therapy: Past, Present and Future

Chilakamarthi, U., & Giribabu, L. (2017) · The Chemical Record · doi:10.1002/tcr.201600121 · Cited by 574

Photo-oxidation of proteins

Pattison, D. I., Rahmanto, A. S., & Davies, M. J. (2012) · Photochemical & Photobiological Sciences · doi:10.1039/c1pp05164d · Cited by 573

UV-Emitting Upconversion-Based TiO2 Photosensitizing Nanoplatform: Near-Infrared Light Mediated in Vivo Photodynamic Therapy via Mitochondria-Involved Apoptosis Pathway

Hou, Z., Zhang, Y., Deng, K., Chen, Y., Li, X., Deng, X., Cheng, Z., Lian, H., Li, C., & Lin, J. (2015) · ACS Nano · doi:10.1021/nn506107c · Cited by 570

BIOLUMINESCENCE

Wilson, T., & Hastings, J. W. (1998) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.14.1.197 · Cited by 570

2D Nanomaterials for Cancer Theranostic Applications

Cheng, L., Wang, X., Gong, F., Liu, T., & Liu, Z. (2020) · Advanced Materials · doi:10.1002/adma.201902333 · Cited by 569

Two-photon excitation nanoparticles for photodynamic therapy

Shen, Y., Shuhendler, A. J., Ye, D., Xu, J.-J., & Chen, H.-Y. (2016) · Chemical Society Reviews · doi:10.1039/c6cs00442c · Cited by 568

A Smart Photosensitizer–Manganese Dioxide Nanosystem for Enhanced Photodynamic Therapy by Reducing Glutathione Levels in Cancer Cells

Fan, H., Yan, G., Zhao, Z., Hu, X., Zhang, W., Liu, H., Fu, X., Fu, T., Zhang, X., & Tan, W. (2016) · Angewandte Chemie International Edition · doi:10.1002/anie.201510748 · Cited by 567

Near‐Infrared‐Light‐Activatable Nanomaterial‐Mediated Phototheranostic Nanomedicines: An Emerging Paradigm for Cancer Treatment

Vankayala, R., & Hwang, K. C. (2018) · Advanced Materials · doi:10.1002/adma.201706320 · Cited by 557

Chemistry and biochemistry of lipid peroxidation products

Guéraud, F., Atalay, M., Bresgen, N., Cipak, A., Eckl, P. M., Huc, L., Jouanin, I., Siems, W., & Uchida, K. (2010) · Free Radical Research · doi:10.3109/10715762.2010.498477 · Cited by 552

Two-Photon Photodynamic Therapy

BHAWALKAR, J. D., KUMAR, N. D., ZHAO, C.-F., & PRASAD, P. N. (1997) · Journal of Clinical Laser Medicine & Surgery · doi:10.1089/clm.1997.15.201 · Cited by 543

Graphene mode locked, wavelength-tunable, dissipative soliton fiber laser

Zhang, H., Tang, D., Knize, R. J., Zhao, L., Bao, Q., & Loh, K. P. (2010) · Applied Physics Letters · doi:10.1063/1.3367743 · Cited by 535

Mechanical Isolation of Highly Stable Antimonene under Ambient Conditions

Ares, P., Aguilar‐Galindo, F., Rodríguez‐San‐Miguel, D., Aldave, D. A., Díaz‐Tendero, S., Alcamí, M., Martín, F., Gómez‐Herrero, J., & Zamora, F. (2016) · Advanced Materials · doi:10.1002/adma.201602128 · Cited by 526

Structural basis for the spectral difference in luciferase bioluminescence

Nakatsu, T., Ichiyama, S., Hiratake, J., Saldanha, A., Kobashi, N., Sakata, K., & Kato, H. (2006) · Nature · doi:10.1038/nature04542 · Cited by 517

Marriage of Scintillator and Semiconductor for Synchronous Radiotherapy and Deep Photodynamic Therapy with Diminished Oxygen Dependence

Zhang, C., Zhao, K., Bu, W., Ni, D., Liu, Y., Feng, J., & Shi, J. (2015) · Angewandte Chemie International Edition · doi:10.1002/anie.201408472 · Cited by 516

Liposomes for photodynamic therapy

Derycke, A. (2004) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2003.07.014 · Cited by 512

Planer nano-graphenes from camphor by CVD

Somani, P. R., Somani, S. P., & Umeno, M. (2006) · Chemical Physics Letters · doi:10.1016/j.cplett.2006.06.081 · Cited by 504

Phosphorene: Synthesis, Scale-Up, and Quantitative Optical Spectroscopy

Woomer, A. H., Farnsworth, T. W., Hu, J., Wells, R. A., Donley, C. L., & Warren, S. C. (2015) · ACS Nano · doi:10.1021/acsnano.5b02599 · Cited by 498

In Vivo Targeted Deep-Tissue Photodynamic Therapy Based on Near-Infrared Light Triggered Upconversion Nanoconstruct

Cui, S., Yin, D., Chen, Y., Di, Y., Chen, H., Ma, Y., Achilefu, S., & Gu, Y. (2013) · ACS Nano · doi:10.1021/nn304872n · Cited by 497

Recent progress on semiconducting polymer nanoparticles for molecular imaging and cancer phototherapy

Li, J., Rao, J., & Pu, K. (2018) · Biomaterials · doi:10.1016/j.biomaterials.2017.11.025 · Cited by 469

In Vitro and In Vivo Uncaging and Bioluminescence Imaging by Using Photocaged Upconversion Nanoparticles

Yang, Y., Shao, Q., Deng, R., Wang, C., Teng, X., Cheng, K., Cheng, Z., Huang, L., Liu, Z., Liu, X., et al. (2012) · Angewandte Chemie International Edition · doi:10.1002/anie.201107919 · Cited by 467

Lipid-based systemic delivery of siRNA

Tseng, Y.-C., Mozumdar, S., & Huang, L. (2009) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2009.03.003 · Cited by 463

Small-molecule kinase inhibitors: an analysis of FDA-approved drugs

Wu, P., Nielsen, T. E., & Clausen, M. H. (2016) · Drug Discovery Today · doi:10.1016/j.drudis.2015.07.008 · Cited by 457

Upconversion Nanoparticles for Photodynamic Therapy and Other Cancer Therapeutics

Wang, C., Cheng, L., & Liu, Z. (2013) · Theranostics · doi:10.7150/thno.5284 · Cited by 456

Nanoscale metal−organic frameworks for combined photodynamic & radiation therapy in cancer treatment

Liu, J., Yang, Y., Zhu, W., Yi, X., Dong, Z., Xu, X., Chen, M., Yang, K., Lu, G., Jiang, L., et al. (2016) · Biomaterials · doi:10.1016/j.biomaterials.2016.04.034 · Cited by 447

Graphene quantum dots as autophagy-inducing photodynamic agents

Markovic, Z. M., Ristic, B. Z., Arsikin, K. M., Klisic, D. G., Harhaji-Trajkovic, L. M., Todorovic-Markovic, B. M., Kepic, D. P., Kravic-Stevovic, T. K., Jovanovic, S. P., Milenkovic, M. M., et al. (2012) · Biomaterials · doi:10.1016/j.biomaterials.2012.06.060 · Cited by 441

Photodynamic Therapy: Current Status and Future Directions

Benov, L. (2015) · Medical Principles and Practice · doi:10.1159/000362416 · Cited by 421

Semiconducting Polymer Nanomaterials as Near-Infrared Photoactivatable Protherapeutics for Cancer

Li, J., & Pu, K. (2020) · Accounts of Chemical Research · doi:10.1021/acs.accounts.9b00569 · Cited by 412

Induction of cytotoxicity by photoexcited TiO2 particles.

Cai, R., Kubota, Y., Shuin, T., Sakai, H., Hashimoto, K., & Fujishima, A. (1992) · PubMed · Cited by 410

Breaking the depth dependency of phototherapy with Cerenkov radiation and low-radiance-responsive nanophotosensitizers

Kotagiri, N., Sudlow, G. P., Akers, W. J., & Achilefu, S. (2015) · Nature Nanotechnology · doi:10.1038/nnano.2015.17 · Cited by 404

Reactive species formed on proteins exposed to singlet oxygen

Davies, M. J. (2004) · Photochemical & Photobiological Sciences · doi:10.1039/b307576c · Cited by 400

Photothermal cancer immunotherapy by erythrocyte membrane-coated black phosphorus formulation

Liang, X., Ye, X., Wang, C., Xing, C., Miao, Q., Xie, Z., Chen, X., Zhang, X., Zhang, H., & Mei, L. (2019) · Journal of Controlled Release · doi:10.1016/j.jconrel.2019.01.027 · Cited by 386

Nanoscintillator-Mediated X-ray Inducible Photodynamic Therapy for In Vivo Cancer Treatment

Chen, H., Wang, G. D., Chuang, Y.-J., Zhen, Z., Chen, X., Biddinger, P., Hao, Z., Liu, F., Shen, B., Pan, Z., et al. (2015) · Nano Letters · doi:10.1021/nl504044p · Cited by 381

Intracellular signaling mechanisms in photodynamic therapy

Almeida, R. D., Manadas, B. J., Carvalho, A. P., & Duarte, C. B. (2004) · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · doi:10.1016/j.bbcan.2004.05.003 · Cited by 379

Cell Membrane Coated Semiconducting Polymer Nanoparticles for Enhanced Multimodal Cancer Phototheranostics

Li, J., Zhen, X., Lyu, Y., Jiang, Y., Huang, J., & Pu, K. (2018) · ACS Nano · doi:10.1021/acsnano.8b04066 · Cited by 377

Catalase-Integrated Hyaluronic Acid as Nanocarriers for Enhanced Photodynamic Therapy in Solid Tumor

Phua, S. Z. F., Yang, G., Lim, W. Q., Verma, A., Chen, H., Thanabalu, T., & Zhao, Y. (2019) · ACS Nano · doi:10.1021/acsnano.9b01087 · Cited by 375

Designing Multi‐Branched Gold Nanoechinus for NIR Light Activated Dual Modal Photodynamic and Photothermal Therapy in the Second Biological Window

Vijayaraghavan, P., Liu, C., Vankayala, R., Chiang, C., & Hwang, K. C. (2014) · Advanced Materials · doi:10.1002/adma.201400703 · Cited by 372

Optical tuning of exciton and trion emissions in monolayer phosphorene

Yang, J., Xu, R., Pei, J., Myint, Y. W., Wang, F., Wang, Z., Zhang, S., Yu, Z., & Lu, Y. (2015) · Light: Science & Applications · doi:10.1038/lsa.2015.85 · Cited by 363

Light‐Triggered In Situ Gelation to Enable Robust Photodynamic‐Immunotherapy by Repeated Stimulations

Meng, Z., Zhou, X., Xu, J., Han, X., Dong, Z., Wang, H., Zhang, Y., She, J., Xu, L., Wang, C., et al. (2019) · Advanced Materials · doi:10.1002/adma.201900927 · Cited by 362

Biotechnological applications of bioluminescence and chemiluminescence

RODA, A. (2004) · Trends in Biotechnology · doi:10.1016/j.tibtech.2004.03.011 · Cited by 357

Assembly of Aptamer Switch Probes and Photosensitizer on Gold Nanorods for Targeted Photothermal and Photodynamic Cancer Therapy

Wang, J., Zhu, G., You, M., Song, E., Shukoor, M. I., Zhang, K., Altman, M. B., Chen, Y., Zhu, Z., Huang, C. Z., et al. (2012) · ACS Nano · doi:10.1021/nn300694v · Cited by 357

Black phosphorus quantum dots: synthesis, properties, functionalized modification and applications

Gui, R., Jin, H., Wang, Z., & Li, J. (2018) · Chemical Society Reviews · doi:10.1039/c8cs00387d · Cited by 356

Imaging‐Guided pH‐Sensitive Photodynamic Therapy Using Charge Reversible Upconversion Nanoparticles under Near‐Infrared Light

Wang, C., Cheng, L., Liu, Y., Wang, X., Ma, X., Deng, Z., Li, Y., & Liu, Z. (2013) · Advanced Functional Materials · doi:10.1002/adfm.201202992 · Cited by 355

Scintillating Nanoparticles as Energy Mediators for Enhanced Photodynamic Therapy

Kamkaew, A., Chen, F., Zhan, Y., Majewski, R. L., & Cai, W. (2016) · ACS Nano · doi:10.1021/acsnano.6b01401 · Cited by 355

Recent Progresses in Phototherapy‐Synergized Cancer Immunotherapy

Ng, C. W., Li, J., & Pu, K. (2018) · Advanced Functional Materials · doi:10.1002/adfm.201804688 · Cited by 349

Type I photodynamic therapy by organic–inorganic hybrid materials: From strategies to applications

Wang, Y.-Y., Liu, Y.-C., Sun, H., & Guo, D.-S. (2019) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2019.05.016 · Cited by 344

Generation of reactive oxygen species induced by gold nanoparticles under x-ray and UV Irradiations

Misawa, M., & Takahashi, J. (2011) · Nanomedicine: Nanotechnology, Biology and Medicine · doi:10.1016/j.nano.2011.01.014 · Cited by 342

Polymeric micelles to deliver photosensitizers for photodynamic therapy

VANNOSTRUM, C. (2004) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2003.07.013 · Cited by 342

A Semiconducting Polymer Nano‐prodrug for Hypoxia‐Activated Photodynamic Cancer Therapy

Cui, D., Huang, J., Zhen, X., Li, J., Jiang, Y., & Pu, K. (2019) · Angewandte Chemie International Edition · doi:10.1002/anie.201814730 · Cited by 340

Photodynamic therapy in dentistry: a literature review

Gursoy, H., Ozcakir-Tomruk, C., Tanalp, J., & Yılmaz, S. (2013) · Clinical Oral Investigations · doi:10.1007/s00784-012-0845-7 · Cited by 335

Oxygenic Hybrid Semiconducting Nanoparticles for Enhanced Photodynamic Therapy

Zhu, H., Li, J., Qi, X., Chen, P., & Pu, K. (2018) · Nano Letters · doi:10.1021/acs.nanolett.7b04759 · Cited by 333

A Hypoxia‐Responsive Albumin‐Based Nanosystem for Deep Tumor Penetration and Excellent Therapeutic Efficacy

Yang, G., Phua, S. Z. F., Lim, W. Q., Zhang, R., Feng, L., Liu, G., Wu, H., Bindra, A. K., Jana, D., Liu, Z., et al. (2019) · Advanced Materials · doi:10.1002/adma.201901513 · Cited by 333

Enhanced Photodynamic Therapy by Reduced Levels of Intracellular Glutathione Obtained By Employing a Nano‐MOF with CuII as the Active Center

Zhang, W., Lu, J., Gao, X., Li, P., Zhang, W., Ma, Y., Wang, H., & Tang, B. (2018) · Angewandte Chemie International Edition · doi:10.1002/anie.201710800 · Cited by 328

Release of cytochrome c and activation of pro-caspase-9 following lysosomal photodamage involves bid cleavage

Reiners Jr, J. J., Caruso, J. A., Mathieu, P., Chelladurai, B., Yin, X.-M., & Kessel, D. (2002) · Cell Death & Differentiation · doi:10.1038/sj.cdd.4401048 · Cited by 326

Recent Progress in Near Infrared Light Triggered Photodynamic Therapy

Deng, K., Li, C., Huang, S., Xing, B., Jin, D., Zeng, Q., Hou, Z., & Lin, J. (2017) · Small · doi:10.1002/smll.201702299 · Cited by 324

Recent Advances in Tumor Microenvironment Hydrogen Peroxide-Responsive Materials for Cancer Photodynamic Therapy

Yang, N., Xiao, W., Song, X., Wang, W., & Dong, X. (2020) · Nano-Micro Letters · doi:10.1007/s40820-019-0347-0 · Cited by 324

Imatinib Mesylate Is a Potent Inhibitor of the ABCG2 (BCRP) Transporter and Reverses Resistance to Topotecan and SN-38 in Vitro

Houghton, P. J., Germain, G. S., Harwood, F. C., Schuetz, J. D., Stewart, C. F., Buchdunger, E., & Traxler, P. (2004) · Cancer Research · doi:10.1158/0008-5472.can-03-3344 · Cited by 323

Mechanisms of Resistance to Photodynamic Therapy

Casas, A., Di Venosa, G., Hasan, T., & Batlle, A. (2011) · Current Medicinal Chemistry · doi:10.2174/092986711795843272 · Cited by 322

Influence of Photodynamic Therapy on Expression of Vascular Endothelial Growth Factor (VEGF), VEGF Receptor 3, and Pigment Epithelium–Derived Factor

Schmidt-Erfurth, U., Schlo¨tzer-Schrehard, U., Cursiefen, C., Michels, S., Beckendorf, A., & Naumann, G. O. H. (2003) · Investigative Opthalmology & Visual Science · doi:10.1167/iovs.02-1115 · Cited by 317

Manipulating tumor hypoxia toward enhanced photodynamic therapy (PDT)

Dang, J., He, H., Chen, D., & Yin, L. (2017) · Biomaterials Science · doi:10.1039/c7bm00392g · Cited by 317

Titanium-Based Nanoscale Metal–Organic Framework for Type I Photodynamic Therapy

Lan, G., Ni, K., Veroneau, S. S., Feng, X., Nash, G. T., Luo, T., Xu, Z., & Lin, W. (2019) · Journal of the American Chemical Society · doi:10.1021/jacs.8b13804 · Cited by 317

O2-generating MnO2 nanoparticles for enhanced photodynamic therapy of bladder cancer by ameliorating hypoxia

Lin, T., Zhao, X., Zhao, S., Yu, H., Cao, W., Chen, W., Wei, H., & Guo, H. (2018) · Theranostics · doi:10.7150/thno.22465 · Cited by 304

Organic Semiconducting Pro‐nanostimulants for Near‐Infrared Photoactivatable Cancer Immunotherapy

Li, J., Cui, D., Huang, J., He, S., Yang, Z., Zhang, Y., Luo, Y., & Pu, K. (2019) · Angewandte Chemie International Edition · doi:10.1002/anie.201906288 · Cited by 304

Vascular Effects of Photodynamic Therapy

FINGAR, V. H. (1996) · Journal of Clinical Laser Medicine & Surgery · doi:10.1089/clm.1996.14.323 · Cited by 302

Molecular and nanoengineering approaches towards activatable cancer immunotherapy

Zhang, C., & Pu, K. (2020) · Chemical Society Reviews · doi:10.1039/c9cs00773c · Cited by 302

Luminescent, Oxygen‐Supplying, Hemoglobin‐Linked Conjugated Polymer Nanoparticles for Photodynamic Therapy

Jiang, L., Bai, H., Liu, L., Lv, F., Ren, X., & Wang, S. (2019) · Angewandte Chemie International Edition · doi:10.1002/anie.201905884 · Cited by 288

A High-Performance Nanobio Photocatalyst for Targeted Brain Cancer Therapy

Rozhkova, E. A., Ulasov, I., Lai, B., Dimitrijevic, N. M., Lesniak, M. S., & Rajh, T. (2009) · Nano Letters · doi:10.1021/nl901610f · Cited by 284

Nanomaterials for Photo-Based Diagnostic and Therapeutic Applications

Menon, J. U., Jadeja, P., Tambe, P., Vu, K., Yuan, B., & Nguyen, K. T. (2013) · Theranostics · doi:10.7150/thno.5327 · Cited by 284

Active targeting of gold nanoparticles as cancer therapeutics

Goddard, Z. R., Marín, M. J., Russell, D. A., & Searcey, M. (2020) · Chemical Society Reviews · doi:10.1039/d0cs01121e · Cited by 282

Mesoporous silica materials: From physico-chemical properties to enhanced dissolution of poorly water-soluble drugs

Maleki, A., Kettiger, H., Schoubben, A., Rosenholm, J. M., Ambrogi, V., & Hamidi, M. (2017) · Journal of Controlled Release · doi:10.1016/j.jconrel.2017.07.047 · Cited by 281

Application of Near-Infrared Dyes for Tumor Imaging, Photothermal, and Photodynamic Therapies

Yuan, A., Wu, J., Tang, X., Zhao, L., Xu, F., & Hu, Y. (2013) · Journal of Pharmaceutical Sciences · doi:10.1002/jps.23356 · Cited by 280

Photodynamic therapy: A mitochondrial inducer of apoptosis

Kessel, D., & Luo, Y. (1999) · Cell Death & Differentiation · doi:10.1038/sj.cdd.4400446 · Cited by 279

Directing Assembly and Disassembly of 2D MoS2 Nanosheets with DNA for Drug Delivery

Li, B. L., Setyawati, M. I., Chen, L., Xie, J., Ariga, K., Lim, C.-T., Garaj, S., & Leong, D. T. (2017) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.7b02529 · Cited by 279

Activatable Polymer Nanoenzymes for Photodynamic Immunometabolic Cancer Therapy

Zeng, Z., Zhang, C., Li, J., Cui, D., Jiang, Y., & Pu, K. (2021) · Advanced Materials · doi:10.1002/adma.202007247 · Cited by 276

ER stress, autophagy and immunogenic cell death in photodynamic therapy-induced anti-cancer immune responses

Garg, A. D., & Agostinis, P. (2014) · Photochemical & Photobiological Sciences · doi:10.1039/c3pp50333j · Cited by 276

Photodynamic Diagnosis in Urology: State-of-the-Art

Jocham, D., Stepp, H., & Waidelich, R. (2008) · European Urology · doi:10.1016/j.eururo.2007.11.048 · Cited by 263

Automated mass spectrometry imaging of over 2000 proteins from tissue sections at 100-μm spatial resolution

Piehowski, P. D., Zhu, Y., Bramer, L. M., Stratton, K. G., Zhao, R., Orton, D. J., Moore, R. J., Yuan, J., Mitchell, H. D., Gao, Y., et al. (2020) · Nature Communications · doi:10.1038/s41467-019-13858-z · Cited by 263

Exocytosis of nanoparticles from cells: Role in cellular retention and toxicity

Sakhtianchi, R., Minchin, R. F., Lee, K.-B., Alkilany, A. M., Serpooshan, V., & Mahmoudi, M. (2013) · Advances in Colloid and Interface Science · doi:10.1016/j.cis.2013.10.013 · Cited by 262

Nanocomposite‐Based Photodynamic Therapy Strategies for Deep Tumor Treatment

Hu, J., Tang, Y., Elmenoufy, A. H., Xu, H., Cheng, Z., & Yang, X. (2015) · Small · doi:10.1002/smll.201501923 · Cited by 262

Photoactivatable Organic Semiconducting Pro-nanoenzymes

Li, J., Huang, J., Lyu, Y., Huang, J., Jiang, Y., Xie, C., & Pu, K. (2019) · Journal of the American Chemical Society · doi:10.1021/jacs.8b13507 · Cited by 261

Black Phosphorus–Polymer Composites for Pulsed Lasers

Mu, H., Lin, S., Wang, Z., Xiao, S., Li, P., Chen, Y., Zhang, H., Bao, H., Lau, S. P., Pan, C., et al. (2015) · Advanced Optical Materials · doi:10.1002/adom.201500336 · Cited by 260

Tumor cell survival pathways activated by photodynamic therapy: a molecular basis for pharmacological inhibition strategies

Broekgaarden, M., Weijer, R., van Gulik, T. M., Hamblin, M. R., & Heger, M. (2015) · Cancer and Metastasis Reviews · doi:10.1007/s10555-015-9588-7 · Cited by 255

Self‐Supplying O2 through the Catalase‐Like Activity of Gold Nanoclusters for Photodynamic Therapy against Hypoxic Cancer Cells

Liu, C., Wu, T., Liu, C., Chen, K., Chen, Y., Chen, G., & Lin, S. (2017) · Small · doi:10.1002/smll.201700278 · Cited by 254

Gold nanoshells-mediated bimodal photodynamic and photothermal cancer treatment using ultra-low doses of near infra-red light

Vankayala, R., Lin, C.-C., Kalluru, P., Chiang, C.-S., & Hwang, K. C. (2014) · Biomaterials · doi:10.1016/j.biomaterials.2014.03.065 · Cited by 251

X-Ray Induced Photodynamic Therapy: A Combination of Radiotherapy and Photodynamic Therapy

Wang, G. D., Nguyen, H. T., Chen, H., Cox, P. B., Wang, L., Nagata, K., Hao, Z., Wang, A., Li, Z., & Xie, J. (2016) · Theranostics · doi:10.7150/thno.16141 · Cited by 251

Peptide self-assembly for nanomaterials: the old new kid on the block

De Santis, E., & Ryadnov, M. G. (2015) · Chemical Society Reviews · doi:10.1039/c5cs00470e · Cited by 249

Mitochondrial specific photodynamic therapy by rare-earth nanoparticles mediated near-infrared graphene quantum dots

Zhang, D., Wen, L., Huang, R., Wang, H., Hu, X., & Xing, D. (2018) · Biomaterials · doi:10.1016/j.biomaterials.2017.10.034 · Cited by 248

Cancer-Cell-Activated Photodynamic Therapy Assisted by Cu(II)-Based Metal–Organic Framework

Wang, Y., Wu, W., Liu, J., Manghnani, P. N., Hu, F., Ma, D., Teh, C., Wang, B., & Liu, B. (2019) · ACS Nano · doi:10.1021/acsnano.9b01665 · Cited by 248

Smart Nanovesicle-Mediated Immunogenic Cell Death through Tumor Microenvironment Modulation for Effective Photodynamic Immunotherapy

Yang, W., Zhang, F., Deng, H., Lin, L., Wang, S., Kang, F., Yu, G., Lau, J., Tian, R., Zhang, M., et al. (2020) · ACS Nano · doi:10.1021/acsnano.9b07212 · Cited by 248

Capturing variation impact on molecular interactions in the IMEx Consortium mutations data set

The IMEx Consortium Curators, Khadake, J., Meldal, B., Panni, S., Thorneycroft, D., van Roey, K., Abbani, S., Salwinski, L., Pellegrini, M., Iannuccelli, M., et al. (2019) · Nature Communications · doi:10.1038/s41467-018-07709-6 · Cited by 247

Tongue cancer tailored photosensitizers for NIR-II fluorescence imaging guided precise treatment

Yin, B., Qin, Q., Li, Z., Wang, Y., Liu, X., Liu, Y., Huan, S., Zhang, X., & Song, G. (2022) · Nano Today · doi:10.1016/j.nantod.2022.101550 · Cited by 65

Multifunctional Magnetic Nanoparticles for Dynamic Imaging and Therapy

Ko, M. J., Hong, H., Choi, H., Kang, H., & Kim, D. (2022) · Advanced NanoBiomed Research · doi:10.1002/anbr.202200053 · Cited by 29