Selective increases of bifidobacteria in gut microflora improve high-fat-diet-induced diabetes in mice through a mechanism associated with endotoxaemia

Obesity is associated with macrophage accumulation in adipose tissue

Weisberg, S. P., McCann, D., Desai, M., Rosenbaum, M., Leibel, R. L., & Ferrante, A. W. (2003) · Journal of Clinical Investigation · doi:10.1172/jci200319246 · Cited by 10,041

Human gut microbes associated with obesity

Ley, R. E., Turnbaugh, P. J., Klein, S., & Gordon, J. I. (2006) · Nature · doi:10.1038/4441022a · Cited by 8,785

The gut microbiota as an environmental factor that regulates fat storage

Bäckhed, F., Ding, H., Wang, T., Hooper, L. V., Koh, G. Y., Nagy, A., Semenkovich, C. F., & Gordon, J. I. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0407076101 · Cited by 6,245

Obesity alters gut microbial ecology

Ley, R. E., Bäckhed, F., Turnbaugh, P., Lozupone, C. A., Knight, R. D., & Gordon, J. I. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0504978102 · Cited by 6,176

Host-Bacterial Mutualism in the Human Intestine

Bäckhed, F., Ley, R. E., Sonnenburg, J. L., Peterson, D. A., & Gordon, J. I. (2005) · Science · doi:10.1126/science.1104816 · Cited by 5,277

Inflammation, stress, and diabetes

Wellen, K. E., & Hotamisligil, G. S. (2005) · Journal of Clinical Investigation · doi:10.1172/jci25102 · Cited by 4,143

Mechanisms underlying the resistance to diet-induced obesity in germ-free mice

Bäckhed, F., Manchester, J. K., Semenkovich, C. F., & Gordon, J. I. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0605374104 · Cited by 2,615

From Dietary Fiber to Host Physiology: Short-Chain Fatty Acids as Key Bacterial Metabolites

Koh, A., De Vadder, F., Kovatcheva-Datchary, P., & Bäckhed, F. (2016) · Cell · doi:10.1016/j.cell.2016.05.041 · Cited by 7,070

Changes in gut microbiota control metabolic endotoxemia-induced inflammation in high-fat diet-induced obesity and diabetes in mice

Cani, P. D., Bibiloni, R., Knauf, C., Waget, A., Neyrinck, A. M., Delzenne, N. M., & Burcelin, R. (2008) · Diabetes · doi:10.2337/db07-1403 · Cited by 4,819

Host-gut microbiota metabolic interactions

Nicholson, J. K., Holmes, E., Kinross, J., Burcelin, R., Gibson, G., Jia, W., & Pettersson, S. (2012) · Science · doi:10.1126/science.1223813 · Cited by 4,760

Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity

Everard, A., Belzer, C., Geurts, L., Ouwerkerk, J. P., Druart, C., Bindels, L. B., Guiot, Y., Derrien, M., Muccioli, G. G., Delzenne, N. M., et al. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1219451110 · Cited by 4,511

Functional interactions between the gut microbiota and host metabolism

Tremaroli, V., & Bäckhed, F. (2012) · Nature · doi:10.1038/nature11552 · Cited by 4,387

Gut microbiota in health and disease

Sekirov, I., Russell, S. L., Antunes, L. C. M., & Finlay, B. B. (2010) · Physiological Reviews · doi:10.1152/physrev.00045.2009 · Cited by 4,182

Gut Microbiota in Human Adults with Type 2 Diabetes Differs from Non-Diabetic Adults

Larsen, N., Vogensen, F. K., van den Berg, F. W. J., Nielsen, D. S., Andreasen, A. S., Pedersen, B. K., Al-Soud, W. A., Sørensen, S. J., Hansen, L. H., & Jakobsen, M. (2010) · PLoS ONE · doi:10.1371/journal.pone.0009085 · Cited by 2,952

The impact of dietary fiber on gut microbiota in host health and disease

Makki, K., Deehan, E. C., Walter, J., & Bäckhed, F. (2018) · Cell Host & Microbe · doi:10.1016/j.chom.2018.05.012 · Cited by 2,517

Changes in gut microbiota control inflammation in obese mice through a mechanism involving GLP-2-driven improvement of gut permeability

Cani, P. D., Possemiers, S., Van de Wiele, T., Guiot, Y., Everard, A., Rottier, O., Geurts, L., Naslain, D., Neyrinck, A., Lambert, D. M., et al. (2009) · Gut · doi:10.1136/gut.2008.165886 · Cited by 2,518

Diet–microbiota interactions as moderators of human metabolism

Sonnenburg, J. L., & Bäckhed, F. (2016) · Nature · doi:10.1038/nature18846 · Cited by 2,257

Short-chain fatty acids in control of body weight and insulin sensitivity

Canfora, E. E., Jocken, J. W., & Blaak, E. E. (2015) · Nature Reviews Endocrinology · doi:10.1038/nrendo.2015.128 · Cited by 2,298

Microbiota-Generated Metabolites Promote Metabolic Benefits via Gut-Brain Neural Circuits

De Vadder, F., Kovatcheva-Datchary, P., Goncalves, D., Vinera, J., Zitoun, C., Duchampt, A., Bäckhed, F., & Mithieux, G. (2014) · Cell · doi:10.1016/j.cell.2013.12.016 · Cited by 2,200

You are what you eat: Diet, health and the gut microbiota

Zmora, N., Suez, J., & Elinav, E. (2019) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/s41575-018-0061-2 · Cited by 1,792

Gut microbiota in cardiovascular health and disease

Tang, W. H. W., Kitai, T., & Hazen, S. L. (2017) · Circulation Research · doi:10.1161/circresaha.117.309715 · Cited by 1,670

The impact of diet and lifestyle on gut microbiota and human health

Conlon, M., & Bird, A. (2014) · Nutrients · doi:10.3390/nu7010017 · Cited by 1,567

Impact of the gut microbiota on inflammation, obesity, and metabolic disease

Boulangé, C. L., Neves, A. L., Chilloux, J., Nicholson, J. K., & Dumas, M.-E. (2016) · Genome Medicine · doi:10.1186/s13073-016-0303-2 · Cited by 1,438

How glycan metabolism shapes the human gut microbiota

Koropatkin, N. M., Cameron, E. A., & Martens, E. C. (2012) · Nature Reviews Microbiology · doi:10.1038/nrmicro2746 · Cited by 1,419

Human colonic microbiota associated with diet, obesity and weight loss

Duncan, S. H., Lobley, G. E., Holtrop, G., Ince, J., Johnstone, A. M., Louis, P., & Flint, H. J. (2008) · International Journal of Obesity · doi:10.1038/ijo.2008.155 · Cited by 1,222

Differential Adaptation of Human Gut Microbiota to Bariatric Surgery–Induced Weight Loss

Furet, J.-P., Kong, L.-C., Tap, J., Poitou, C., Basdevant, A., Bouillot, J.-L., Mariat, D., Corthier, G., Doré, J., Henegar, C., et al. (2010) · Diabetes · doi:10.2337/db10-0253 · Cited by 1,173

A polyphenol-rich cranberry extract protects from diet-induced obesity, insulin resistance and intestinal inflammation in association with increased Akkermansia spp. population in the gut microbiota of mice

Anhê, F. F., Roy, D., Pilon, G., Dudonné, S., Matamoros, S., Varin, T. V., Garofalo, C., Moine, Q., Desjardins, Y., Levy, E., et al. (2015) · Gut · doi:10.1136/gutjnl-2014-307142 · Cited by 1,137

The intestinal microbiota fuelling metabolic inflammation

Tilg, H., Zmora, N., Adolph, T. E., & Elinav, E. (2020) · Nature Reviews Immunology · doi:10.1038/s41577-019-0198-4 · Cited by 1,089

Dietary factors and low-grade inflammation in relation to overweight and obesity

Calder, P. C., Ahluwalia, N., Brouns, F., Buetler, T., Clement, K., Cunningham, K., Esposito, K., Jönsson, L. S., Kolb, H., Lansink, M., et al. (2011) · British Journal of Nutrition · doi:10.1017/s0007114511005460 · Cited by 1,098

Responses of Gut Microbiota and Glucose and Lipid Metabolism to Prebiotics in Genetic Obese and Diet-Induced Leptin-Resistant Mice

Everard, A., Lazarevic, V., Derrien, M., Girard, M., Muccioli, G. G., Neyrinck, A. M., Possemiers, S., Van Holle, A., François, P., de Vos, W. M., et al. (2011) · Diabetes · doi:10.2337/db11-0227 · Cited by 1,076

Impacts of gut bacteria on human health and diseases

Zhang, Y.-J., Li, S., Gan, R.-Y., Zhou, T., Xu, D.-P., & Li, H.-B. (2015) · International Journal of Molecular Sciences · doi:10.3390/ijms16047493 · Cited by 1,055

Interactions between gut microbiota, host genetics and diet relevant to development of metabolic syndromes in mice

Zhang, C., Zhang, M., Wang, S., Han, R., Cao, Y., Hua, W., Mao, Y., Zhang, X., Pang, X., Wei, C., et al. (2010) · The ISME Journal · doi:10.1038/ismej.2009.112 · Cited by 1,024

The influence of diet on the gut microbiota

Scott, K. P., Gratz, S. W., Sheridan, P. O., Flint, H. J., & Duncan, S. H. (2013) · Pharmacological Research · doi:10.1016/j.phrs.2012.10.020 · Cited by 1,052

The role of the gut microbiota in energy metabolism and metabolic disease

Cani, P., & Delzenne, N. (2009) · Current Pharmaceutical Design · doi:10.2174/138161209788168164 · Cited by 974

Bile Acid Is a Host Factor That Regulates the Composition of the Cecal Microbiota in Rats

Islam, K. B. M. S., Fukiya, S., Hagio, M., Fujii, N., Ishizuka, S., Ooka, T., Ogura, Y., Hayashi, T., & Yokota, A. (2011) · Gastroenterology · doi:10.1053/j.gastro.2011.07.046 · Cited by 918

The role of short-chain fatty acids in the interplay between gut microbiota and diet in cardio-metabolic health

Nogal, A., Valdes, A. M., & Menni, C. (2021) · Gut Microbes · doi:10.1080/19490976.2021.1897212 · Cited by 917

Gut microbiota composition is associated with body weight, weight gain and biochemical parameters in pregnant women

Santacruz, A., Collado, M. C., García-Valdés, L., Segura, M. T., Martín-Lagos, J. A., Anjos, T., Martí-Romero, M., Lopez, R. M., Florido, J., Campoy, C., et al. (2010) · British Journal of Nutrition · doi:10.1017/s0007114510000176 · Cited by 868

Obesity, inflammation, and the gut microbiota

Cox, A. J., West, N. P., & Cripps, A. W. (2015) · The Lancet Diabetes & Endocrinology · doi:10.1016/s2213-8587(14)70134-2 · Cited by 869

Involvement of gut microbiota in the development of low-grade inflammation and type 2 diabetes associated with obesity

Cani, P. D., Osto, M., Geurts, L., & Everard, A. (2012) · Gut Microbes · doi:10.4161/gmic.19625 · Cited by 864

Gut microbiome, obesity, and metabolic dysfunction

Tilg, H., & Kaser, A. (2011) · Journal of Clinical Investigation · doi:10.1172/jci58109 · Cited by 860

The Gut Microbiota and Alzheimer’s Disease

Jiang, C., Li, G., Huang, P., Liu, Z., & Zhao, B. (2017) · Journal of Alzheimer's Disease · doi:10.3233/jad-161141 · Cited by 852

Insight into the prebiotic concept: lessons from an exploratory, double blind intervention study with inulin-type fructans in obese women

Dewulf, E. M., Cani, P. D., Claus, S. P., Fuentes, S., Puylaert, P. G., Neyrinck, A. M., Bindels, L. B., de Vos, W. M., Gibson, G. R., Thissen, J.-P., et al. (2013) · Gut · doi:10.1136/gutjnl-2012-303304 · Cited by 825

Akkermansia muciniphila inversely correlates with the onset of inflammation, altered adipose tissue metabolism and metabolic disorders during obesity in mice

Schneeberger, M., Everard, A., Gómez-Valadés, A. G., Matamoros, S., Ramírez, S., Delzenne, N. M., Gomis, R., Claret, M., & Cani, P. D. (2015) · Scientific Reports · doi:10.1038/srep16643 · Cited by 798

Impact of Omega-3 Fatty Acids on the Gut Microbiota

Costantini, L., Molinari, R., Farinon, B., & Merendino, N. (2017) · International Journal of Molecular Sciences · doi:10.3390/ijms18122645 · Cited by 741

The endocannabinoid system links gut microbiota to adipogenesis

Muccioli, G. G., Naslain, D., Bäckhed, F., Reigstad, C. S., Lambert, D. M., Delzenne, N. M., & Cani, P. D. (2010) · Molecular Systems Biology · doi:10.1038/msb.2010.46 · Cited by 691

Insights into the role of the microbiome in obesity and type 2 diabetes

Hartstra, A. V., Bouter, K. E. C., Bäckhed, F., & Nieuwdorp, M. (2015) · Diabetes Care · doi:10.2337/dc14-0769 · Cited by 641

Resistant Starches Types 2 and 4 Have Differential Effects on the Composition of the Fecal Microbiota in Human Subjects

Martínez, I., Kim, J., Duffy, P. R., Schlegel, V. L., & Walter, J. (2010) · PLoS ONE · doi:10.1371/journal.pone.0015046 · Cited by 645

Short chain fatty acids prevent high-fat-diet-induced obesity in mice by regulating g protein-coupled receptors and gut microbiota

Lu, Y., Fan, C., Li, P., Lu, Y., Chang, X., & Qi, K. (2016) · Scientific Reports · doi:10.1038/srep37589 · Cited by 638

Impact of diet and individual variation on intestinal microbiota composition and fermentation products in obese men

Salonen, A., Lahti, L., Salojärvi, J., Holtrop, G., Korpela, K., Duncan, S. H., Date, P., Farquharson, F., Johnstone, A. M., Lobley, G. E., et al. (2014) · The ISME Journal · doi:10.1038/ismej.2014.63 · Cited by 626

Microbiome of prebiotic-treated mice reveals novel targets involved in host response during obesity

Everard, A., Lazarevic, V., Gaïa, N., Johansson, M., Ståhlman, M., Backhed, F., Delzenne, N. M., Schrenzel, J., François, P., & Cani, P. D. (2014) · The ISME Journal · doi:10.1038/ismej.2014.45 · Cited by 598

Structural Changes of Gut Microbiota during Berberine-Mediated Prevention of Obesity and Insulin Resistance in High-Fat Diet-Fed Rats

Zhang, X., Zhao, Y., Zhang, M., Pang, X., Xu, J., Kang, C., Li, M., Zhang, C., Zhang, Z., Zhang, Y., et al. (2012) · PLoS ONE · doi:10.1371/journal.pone.0042529 · Cited by 615

Germ‐free C57BL/6J mice are resistant to high‐fat‐diet‐induced insulin resistance and have altered cholesterol metabolism

Rabot, S., Membrez, M., Bruneau, A., Gérard, P., Harach, T., Moser, M., Raymond, F., Mansourian, R., & Chou, C. J. (2010) · The FASEB Journal · doi:10.1096/fj.10.164921 · Cited by 610

Gut-Microbiota-Brain Axis and Its Effect on Neuropsychiatric Disorders With Suspected Immune Dysregulation

Petra, A. I., Panagiotidou, S., Hatziagelaki, E., Stewart, J. M., Conti, P., & Theoharides, T. C. (2015) · Clinical Therapeutics · doi:10.1016/j.clinthera.2015.04.002 · Cited by 592

The gut microbiota, obesity and insulin resistance

Shen, J., Obin, M. S., & Zhao, L. (2013) · Molecular Aspects of Medicine · doi:10.1016/j.mam.2012.11.001 · Cited by 599

Understanding the role of gut microbiome–host metabolic signal disruption in health and disease

Holmes, E., Li, J. V., Athanasiou, T., Ashrafian, H., & Nicholson, J. K. (2011) · Trends in Microbiology · doi:10.1016/j.tim.2011.05.006 · Cited by 541

A high-fat diet is associated with endotoxemia that originates from the gut

Pendyala, S., Walker, J. M., & Holt, P. R. (2012) · Gastroenterology · doi:10.1053/j.gastro.2012.01.034 · Cited by 546

Gut microbiota, obesity and diabetes

Patterson, E., Ryan, P. M., Cryan, J. F., Dinan, T. G., Ross, R. P., Fitzgerald, G. F., & Stanton, C. (2016) · Postgraduate Medical Journal · doi:10.1136/postgradmedj-2015-133285 · Cited by 552

Dysregulated Microbial Fermentation of Soluble Fiber Induces Cholestatic Liver Cancer

Singh, V., Yeoh, B. S., Chassaing, B., Xiao, X., Saha, P., Aguilera Olvera, R., Lapek, J. D., Zhang, L., Wang, W.-B., Hao, S., et al. (2018) · Cell · doi:10.1016/j.cell.2018.09.004 · Cited by 532

Gut microbiota and metabolic syndrome

Festi, D., Schiumerini, R., Eusebi, L. H., Marasco, G., Taddia, M., & Colecchia, A. (2014) · World Journal of Gastroenterology · doi:10.3748/wjg.v20.i43.16079 · Cited by 534

Diet, Gut Microbiota, and Obesity: Links with Host Genetics and Epigenetics and Potential Applications

Cuevas-Sierra, A., Ramos-Lopez, O., Riezu-Boj, J. I., Milagro, F. I., & Martinez, J. A. (2019) · Advances in Nutrition · doi:10.1093/advances/nmy078 · Cited by 523

Effect of Probiotics on Blood Pressure: A Systematic Review and Meta-Analysis of Randomized, Controlled Trials

Khalesi, S., Sun, J., Buys, N., & Jayasinghe, R. (2014) · Hypertension · doi:10.1161/hypertensionaha.114.03469 · Cited by 516

Can probiotics modulate human disease by impacting intestinal barrier function?

Bron, P. A., Kleerebezem, M., Brummer, R.-J., Cani, P. D., Mercenier, A., MacDonald, T. T., Garcia-Ródenas, C. L., & Wells, J. M. (2017) · British Journal Of Nutrition · doi:10.1017/s0007114516004037 · Cited by 499

Chronic sleep disruption alters gut microbiota, induces systemic and adipose tissue inflammation and insulin resistance in mice

Poroyko, V. A., Carreras, A., Khalyfa, A., Khalyfa, A. A., Leone, V., Peris, E., Almendros, I., Gileles-Hillel, A., Qiao, Z., Hubert, N., et al. (2016) · Scientific Reports · doi:10.1038/srep35405 · Cited by 480

Prebiotic Effects of Wheat Arabinoxylan Related to the Increase in Bifidobacteria, Roseburia and Bacteroides/Prevotella in Diet-Induced Obese Mice

Neyrinck, A. M., Possemiers, S., Druart, C., Van de Wiele, T., De Backer, F., Cani, P. D., Larondelle, Y., & Delzenne, N. M. (2011) · PLoS ONE · doi:10.1371/journal.pone.0020944 · Cited by 465

Structural modulation of gut microbiota in life-long calorie-restricted mice

Zhang, C., Li, S., Yang, L., Huang, P., Li, W., Wang, S., Zhao, G., Zhang, M., Pang, X., Yan, Z., et al. (2013) · Nature Communications · doi:10.1038/ncomms3163 · Cited by 461

Absence of intestinal microbiota does not protect mice from diet-induced obesity

Fleissner, C. K., Huebel, N., Abd El-Bary, M. M., Loh, G., Klaus, S., & Blaut, M. (2010) · British Journal of Nutrition · doi:10.1017/s0007114510001303 · Cited by 436

The role of the gut microbiota in nonalcoholic fatty liver disease

Abu-Shanab, A., & Quigley, E. M. M. (2010) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/nrgastro.2010.172 · Cited by 457

Role of the intestinal microbiome in health and disease: from correlation to causation

de Vos, W. M., & de Vos, E. A. (2012) · Nutrition Reviews · doi:10.1111/j.1753-4887.2012.00505.x · Cited by 440

Dietary supplementation with inulin-propionate ester or inulin improves insulin sensitivity in adults with overweight and obesity with distinct effects on the gut microbiota, plasma metabolome and systemic inflammatory responses: A randomised cross-over trial

Chambers, E. S., Byrne, C. S., Morrison, D. J., Murphy, K. G., Preston, T., Tedford, C., Garcia-Perez, I., Fountana, S., Serrano-Contreras, J. I., Holmes, E., et al. (2019) · Gut · doi:10.1136/gutjnl-2019-318424 · Cited by 443

Role of the Microbiome in Energy Regulation and Metabolism

Nieuwdorp, M., Gilijamse, P. W., Pai, N., & Kaplan, L. M. (2014) · Gastroenterology · doi:10.1053/j.gastro.2014.02.008 · Cited by 421

Aging Gut Microbiota at the Cross-Road between Nutrition, Physical Frailty, and Sarcopenia: Is There a Gut–Muscle Axis?

Ticinesi, A., Lauretani, F., Milani, C., Nouvenne, A., Tana, C., Del Rio, D., Maggio, M., Ventura, M., & Meschi, T. (2017) · Nutrients · doi:10.3390/nu9121303 · Cited by 401

Gut Microbiota Contribute to Age-Related Changes in Skeletal Muscle Size, Composition, and Function: Biological Basis for a Gut-Muscle Axis

Grosicki, G. J., Fielding, R. A., & Lustgarten, M. S. (2018) · Calcified Tissue International · doi:10.1007/s00223-017-0345-5 · Cited by 388

Effect of mother’s weight on infant’s microbiota acquisition, composition, and activity during early infancy: a prospective follow-up study initiated in early pregnancy

Collado, M. C., Isolauri, E., Laitinen, K., & Salminen, S. (2010) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.2010.29877 · Cited by 381

Gut microbiota, enteroendocrine functions and metabolism

Cani, P. D., Everard, A., & Duparc, T. (2013) · Current Opinion in Pharmacology · doi:10.1016/j.coph.2013.09.008 · Cited by 378

Changes in intestinal microbiota composition and metabolism coincide with increased intestinal permeability in young adults under prolonged physiological stress

Karl, J. P., Margolis, L. M., Madslien, E. H., Murphy, N. E., Castellani, J. W., Gundersen, Y., Hoke, A. V., Levangie, M. W., Kumar, R., Chakraborty, N., et al. (2017) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00066.2017 · Cited by 373

Interplay between obesity and associated metabolic disorders: New insights into the gut microbiota

Cani, P. D., & Delzenne, N. M. (2009) · Current Opinion in Pharmacology · doi:10.1016/j.coph.2009.06.016 · Cited by 377

Effects of resveratrol on gut microbiota and fat storage in a mouse model with high-fat-induced obesity

Qiao, Y., Sun, J., Xia, S., Tang, X., Shi, Y., & Le, G. (2014) · Food & Function · doi:10.1039/c3fo60630a · Cited by 367

Dysbiosis of Gut Microbiota [DOGMA]—A novel theory for the development of Polycystic Ovarian Syndrome

Tremellen, K., & Pearce, K. (2012) · Medical Hypotheses · doi:10.1016/j.mehy.2012.04.016 · Cited by 359

Gut Microbiome Dysbiosis and Immunometabolism: New Frontiers for Treatment of Metabolic Diseases

Belizário, J. E., Faintuch, J., & Garay-Malpartida, M. (2018) · Mediators of Inflammation · doi:10.1155/2018/2037838 · Cited by 341

Effects of probiotics on nonalcoholic fatty liver disease: A meta-analysis

Ma, Y.-Y. (2013) · World Journal of Gastroenterology · doi:10.3748/wjg.v19.i40.6911 · Cited by 352

A Mixture of trans-Galactooligosaccharides Reduces Markers of Metabolic Syndrome and Modulates the Fecal Microbiota and Immune Function of Overweight Adults

Vulevic, J., Juric, A., Tzortzis, G., & Gibson, G. R. (2013) · The Journal of Nutrition · doi:10.3945/jn.112.166132 · Cited by 349

Probiotic Bifidobacterium strains and galactooligosaccharides improve intestinal barrier function in obese adults but show no synergism when used together as synbiotics

Krumbeck, J. A., Rasmussen, H. E., Hutkins, R. W., Clarke, J., Shawron, K., Keshavarzian, A., & Walter, J. (2018) · Microbiome · doi:10.1186/s40168-018-0494-4 · Cited by 342

'Gut health': a new objective in medicine?

Bischoff, S. C. (2011) · BMC Medicine · doi:10.1186/1741-7015-9-24 · Cited by 338

Role of Leptin in Inflammation and Vice Versa

Pérez-Pérez, A., Sánchez-Jiménez, F., Vilariño-García, T., & Sánchez-Margalet, V. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21165887 · Cited by 330

Gut–liver axis, nutrition, and non-alcoholic fatty liver disease

Kirpich, I. A., Marsano, L. S., & McClain, C. J. (2015) · Clinical Biochemistry · doi:10.1016/j.clinbiochem.2015.06.023 · Cited by 327

Antiobesity and lipid-lowering effects of Bifidobacterium spp. in high fat diet-induced obese rats

An, H. M., Park, S. Y., Lee, D. K., Kim, J. R., Cha, M. K., Lee, S. W., Lim, H. T., Kim, K. J., & Ha, N. J. (2011) · Lipids in Health and Disease · doi:10.1186/1476-511x-10-116 · Cited by 320

Gut Microbiota, Intestinal Permeability, Obesity‐Induced Inflammation, and Liver Injury

Frazier, T. H., DiBaise, J. K., & McClain, C. J. (2011) · Journal of Parenteral and Enteral Nutrition · doi:10.1177/0148607111413772 · Cited by 306

Do nutrient-gut-microbiota interactions play a role in human obesity, insulin resistance and type 2 diabetes?

Diamant, M., Blaak, E. E., & de Vos, W. M. (2011) · Obesity Reviews · doi:10.1111/j.1467-789x.2010.00797.x · Cited by 308

Metabolic benefits of dietary prebiotics in human subjects: a systematic review of randomised controlled trials

Kellow, N. J., Coughlan, M. T., & Reid, C. M. (2014) · British Journal of Nutrition · doi:10.1017/s0007114513003607 · Cited by 307

Prediabetes and Cardiovascular Disease

Brannick, B., & Dagogo-Jack, S. (2018) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/j.ecl.2017.10.001 · Cited by 293

The Intestinal Microbiota in Metabolic Disease

Woting, A., & Blaut, M. (2016) · Nutrients · doi:10.3390/nu8040202 · Cited by 284

Fermented foods, microbiota, and mental health: ancient practice meets nutritional psychiatry

Selhub, E. M., Logan, A. C., & Bested, A. C. (2014) · Journal of Physiological Anthropology · doi:10.1186/1880-6805-33-2 · Cited by 280

Gender-dependent consequences of chronic olanzapine in the rat: effects on body weight, inflammatory, metabolic and microbiota parameters

Davey, K. J., O’Mahony, S. M., Schellekens, H., O’Sullivan, O., Bienenstock, J., Cotter, P. D., Dinan, T. G., & Cryan, J. F. (2012) · Psychopharmacology · doi:10.1007/s00213-011-2555-2 · Cited by 275

Role of the gut-brain axis in energy and glucose metabolism

Wachsmuth, H. R., Weninger, S. N., & Duca, F. A. (2022) · Experimental & Molecular Medicine · doi:10.1038/s12276-021-00677-w · Cited by 269

Omega-3 polyunsaturated fatty acids critically regulate behaviour and gut microbiota development in adolescence and adulthood

Robertson, R. C., Seira Oriach, C., Murphy, K., Moloney, G. M., Cryan, J. F., Dinan, T. G., Paul Ross, R., & Stanton, C. (2017) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2016.07.145 · Cited by 268

Probiotics modulate gut microbiota and improve insulin sensitivity in DIO mice

Bagarolli, R. A., Tobar, N., Oliveira, A. G., Araújo, T. G., Carvalho, B. M., Rocha, G. Z., Vecina, J. F., Calisto, K., Guadagnini, D., Prada, P. O., et al. (2017) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2017.08.006 · Cited by 266

Is butyrate the link between diet, intestinal microbiota and obesity-related metabolic diseases?

Brahe, L. K., Astrup, A., & Larsen, L. H. (2013) · Obesity Reviews · doi:10.1111/obr.12068 · Cited by 264

Xylo-oligosaccharide (XOS) in combination with inulin modulates both the intestinal environment and immune status in healthy subjects, while XOS alone only shows prebiotic properties

Lecerf, J.-M., Dépeint, F., Clerc, E., Dugenet, Y., Niamba, C. N., Rhazi, L., Cayzeele, A., Abdelnour, G., Jaruga, A., Younes, H., et al. (2012) · British Journal of Nutrition · doi:10.1017/s0007114511007252 · Cited by 262

Resistant Starch Improves Insulin Sensitivity in Metabolic Syndrome

Johnston, K. L., Thomas, E. L., Bell, J. D., Frost, G. S., & Robertson, M. D. (2010) · Diabetic Medicine · doi:10.1111/j.1464-5491.2010.02923.x · Cited by 259

Role of resistant starch in improving gut health, adiposity, and insulin resistance

Keenan, M. J., Zhou, J., Hegsted, M., Pelkman, C., Durham, H. A., Coulon, D. B., & Martin, R. J. (2015) · Advances in Nutrition · doi:10.3945/an.114.007419 · Cited by 243

Effect of probiotic fermented milk (kefir) on glycemic control and lipid profile in type 2 diabetic patients: a randomized double-blind placebo-controlled clinical trial.

(2015) · PubMed Central · Cited by 242

Anti-Obesity Effect of Lactobacillus gasseri BNR17 in High-Sucrose Diet-Induced Obese Mice

Kang, J.-H., Yun, S.-I., Park, M.-H., Park, J.-H., Jeong, S.-Y., & Park, H.-O. (2013) · PLoS ONE · doi:10.1371/journal.pone.0054617 · Cited by 230

Gut microbiota and energy balance: role in obesity

Blaut, M. (2015) · Proceedings of The Nutrition Society · doi:10.1017/s0029665114001700 · Cited by 232

The immune system bridges the gut microbiota with systemic energy homeostasis: focus on TLRs, mucosal barrier, and SCFAs

Spiljar, M., Merkler, D., & Trajkovski, M. (2017) · Frontiers in Immunology · doi:10.3389/fimmu.2017.01353 · Cited by 219

The combination of sport and sport-specific diet is associated with characteristics of gut microbiota: an observational study

Jang, L.-G., Choi, G., Kim, S.-W., Kim, B.-Y., Lee, S., & Park, H. (2019) · Journal of the International Society of Sports Nutrition · doi:10.1186/s12970-019-0290-y · Cited by 224

Imbalances in faecal and duodenal Bifidobacterium species composition in active and non-active coeliac disease

Collado, M. C., Donat, E., Ribes-Koninckx, C., Calabuig, M., & Sanz, Y. (2008) · BMC Microbiology · doi:10.1186/1471-2180-8-232 · Cited by 220

Exercise training modifies gut microbiota in normal and diabetic mice

Lambert, J. E., Myslicki, J. P., Bomhof, M. R., Belke, D. D., Shearer, J., & Reimer, R. A. (2015) · Applied Physiology, Nutrition, and Metabolism · doi:10.1139/apnm-2014-0452 · Cited by 214